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1.
Individuals with alcoholism exhibit poor decision making as reflected by their continued alcohol use despite encountering problems and by low performance in laboratory tasks of decision making. Here, the authors investigated the relative contribution of several distinct processes of executive functions in performance on the Iowa Gambling Task (IGT; A. Bechara, A. R. Damasio, H. Damasio, & S. W. Anderson, 1994) in recently detoxified individuals with alcoholism. Compared to matched healthy participants, individuals with alcoholism showed below-normal scores in the last 20 trials of the IGT as well as on other tasks of executive functions, specifically those assessing the capacity to manipulate information stored in working memory, detect abstract rules, or inhibit prepotent responses. Prepotent response inhibition best predicted performance in the late trials of the IGT, that is, when participants have likely acquired knowledge about the reward/punishment contingencies of the task. These results underline the important role that response inhibition plays in decision making, especially in risky situations, when knowledge of the probability of a given outcome becomes available (i.e. decisions under risk). (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

2.
To assess the working memory system for egocentric distance and place information, delayed matching-to-sample (DMTS) go/no-go tasks were run for each rat. To assess the reference memory system, and to serve as a control for nonmemory deficits, successive discrimination go/no-go tasks were then conducted using the same rats. Rats with hippocampal, but not parietal cortex, lesions were impaired relative to controls in the working memory (DMTS) task for both egocentric distance and place information, although the deficit observed in the working memory task for egocentric distance information by rats with hippocampal lesions was mild. Neither hippocampal nor parietal cortex lesioned rats were impaired relative to controls in the reference memory (successive discrimination) task for either cue. The hippocampus appears to be involved in working memory for egocentric distance and in spatial location information, whereas the parietal cortex is not.  相似文献   

3.
Research has suggested that reduced working memory capacity plays a key role in disinhibited patterns of behavior associated with externalizing psychopathology. In this study, participants (N = 365) completed 2 versions of a go/no-go mixed-incentive learning task that differed in the relative frequency of monetary rewards and punishments for correct and incorrect active-approach responses, respectively. Using separate structural equation models for conventional (hit and false alarm rates) and signal detection theory (signal discriminability and response bias) performance indices, distinct roles for working memory capacity and changes in payoff structure were found. Specifically, results showed that (a) working memory capacity mediated the effects of externalizing psychopathology on false alarms and discriminability of go versus no-go signals; (b) these effects were not moderated by the relative frequency of monetary rewards and punishments; (c) the relative frequency of monetary rewards and punishments moderated the effects of externalizing psychopathology on hits and response bias for go versus no-go responses; and (d) these effects were not mediated by working memory capacity. The findings implicate distinct roles for reduced working memory capacity and poorly modulated active approach and passive avoidance in the link between externalizing psychopathology and behavioral disinhibition. (PsycINFO Database Record (c) 2011 APA, all rights reserved)  相似文献   

4.
This special section includes a set of 5 articles that examine the nature of inter- and intraindividual differences in working memory, using working memory span tasks as the main research tools. These span tasks are different from traditional short-term memory spans (e.g., digit or word span) in that they require participants to maintain some target memory items (e.g., words) while simultaneously performing some other tasks (e.g., reading sentences). In this introduction, a brief discussion of these working memory span tasks and their characteristics is provided first. This is followed by an overview of 2 major theoretic issues that are addressed by the subsequent articles—(a) the factors influencing the inter- and intraindividual differences in working memory performance and (b) the domain generality versus domain specificity of working memory—and also of some important issues that must be kept in mind when readers try to evaluate the claims regarding these 2 theoretical issues. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

5.
Men outperform women on the Iowa Gambling Task (IGT; A. Bechara, H. Damasio, D. Tranel, & A. R. Damasio, 1997). In this study, the authors show that sex differences are not due to differences in general emotional arousal or the abilities to calculate or reverse responses. Imaging studies have shown that, during the IGT, men increase activity in the right dorsolateral prefrontal cortex (PFC) and lateral orbital PFC, whereas women increase activity in the left medial orbital PFC. Deliberation of personal moral (PM) dilemmas also increases activity in medial and lateral dorsal PFC, whereas deliberation of moral impersonal (MI) dilemmas increases activity in lateral dorsal PFC. In the present study, men and women performed the IGT during PM, MI, or control deliberations. Deliberation of only PM dilemmas increased women's IGT performance to the level of men. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

6.
The ability to mitigate interference is of central importance to cognition. Previous research has provided conflicting accounts about whether operations that resolve interference are singular in character or form a family of functions. Here, the authors examined the relationship between interference-resolution processes acting on working memory representations versus responses. The authors combined multiple forms of interference into a single paradigm by merging a directed-forgetting task, which induces proactive interference, with a stop-signal task, which taps response inhibition processes. The results demonstrated that proactive interference and response inhibition produced distinct behavioral signatures that did not interact. By contrast, combining two different measures of response inhibition by merging a go/no-go task variant and a stop signal produced overadditive behavioral interference, demonstrating that different forms of response inhibition tap the same processes. However, not all forms of response conflict interacted, suggesting that inhibition-related functions acting on response selection are dissociable from those acting on response inhibition. These results suggest that inhibition-related functions for memory and responses are dissociable. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

7.
In this article, the first explicit, theory-based comparison of 2-choice and go/no-go variants of 3 experimental tasks is presented. Prior research has questioned whether the underlying core-information processing is different for the 2 variants of a task or whether they differ mostly in response demands. The authors examined 4 different diffusion models for the go/no-go variant of each task along with a standard diffusion model for the 2-choice variant (R. Ratcliff, 1978). The 2-choice and the go/no-go models were fit to data from 4 lexical decision experiments, 1 numerosity discrimination experiment, and 1 recognition memory experiment, each with 2-choice and go/no-go variants. The models that assumed an implicit decision criterion for no-go responses produced better fits than models that did not. The best model was one in which only response criteria and the nondecisional components of processing changed between the 2 variants, supporting the view that the core information on which decisions are based is not different between them. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

8.
The effects of word frequency and spelling-to-sound regularity were examined using standard naming, standard lexical-decision, go/no-go naming, and go/no-go lexical-decision tasks. In both the standard and go/no-go naming tasks, tasks requiring phonological coding, a significant Frequency?×?Regularity interaction was observed. That is, the regularity effect was limited to low-frequency words. In the standard and go/no-go lexical-decision tasks, tasks not requiring phonological coding, no Frequency?×?Regularity interaction was observed. These results indicate not only that the Frequency?×?Regularity interaction is a product of phonological coding processes but also that these processes are similar in the standard and go/no-go naming tasks. Results are discussed in terms of the dual-route and the parallel distributed processing frameworks. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

9.
The authors investigated the behavioral aging effects of Japanese macaques in 3-object discrimination learning tasks: learning-set (LS) formation, go/no-go discrimination learning, and multiple discrimination reversals. Aged monkeys showed deteriorated performance in these tasks compared with younger controls. Hypothesis analysis of LS showed that aged monkeys had difficulty learning the lose-shift component of the hypothesis win-stay-lose-shift with respect to object. Deficits in go/no-go successive discrimination were clear in no-go trials only in the first 2 pairs of 5 tasks. Performance of aged monkeys was severely disturbed from a chance to criterion level in discrimination reversals. These results are attributed not only to increased tendency for perseveration but also to difficulty in associating the reward and the object in aged monkeys and may be related to the decline in the functions of the ventral frontal cortex. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

10.
The role of the prelimbic cortex (PL) in rats was investigated with excitotoxic lesions. PL lesions altered the alternation scores in spontaneous and reinforced spatial delayed-alternation tasks. PL lesions induced a delay in conditioning under a temporal go/no-go alternation schedule but not under a continuous food-reinforcement schedule in a runway. PL lesions had no effect on the acquisition of a standard radial-arm-maze task nor on a fixed-goal location task but disrupted the acquisition of a variable-goal location task in a radial-arm maze. The present results indicate that PL lesions replicated most of the behavioral deficits obtained with larger prefrontal lesions. PL lesions disrupted the acquisition of delayed-variable response tasks while leaving unaffected fixed-response tasks. These results are discussed in relation with a working-memory, a response-selection, and an attentional hypothesis. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

11.
This study was designed to establish whether phonological working memory skills could be assessed in children below 4 yrs of age. A group of 2- and 3-yr-old children were tested on 3 phonological memory measures (digit span, nonword repetition, and word repetition) and were also given tasks that tapped other cognitive skills. Scores on the 3 phonological memory tasks were closely related. In addition, repetition performance was linked with both vocabulary knowledge and articulation rate. Results indicate that phonological memory skills can be reliably assessed in very young children by using conventional serial span and repetition procedures. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

12.
Eight experiments with 98 college students tested the assertion that the capacity limit of short-term memory span (seven plus/minus two "chunks") is related to a fundamental limit in "working memory" of information processing. Each of 2 converging approaches led to findings that deny this hypothesis. The 1st approach examined performance when Ss determined which digit was missing when 8 different digits appeared sequentially in random order. Although this task requires memory for digits, it does not exhibit the properties of short-term memory span (sensitivity to rhythmic patterning and acoustic/articulatory interference). Thus, there must be a working memory that is distinct from the span memory of an ordered-recall task. The 2nd approach required that Ss perform information-processing tasks during the retention interval of memory span. According to the hypothesis that working memory and memory span are equivalent, interference should occur in this paradigm. There was no such interference provided that an initial rehearsal period for the memory span was allowed prior to the intervening task. (77 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

13.
The ability to temporarily maintain information in order to successfully perform a task is important in many daily activities. However, the ability to quickly and accurately update existing mental representations in distracting situations is also imperative in many of these same circumstances. In the current studies, individuals varying in working memory capacity (WMC) performed different varieties of go/no-go tasks that have been hypothesized to measure inhibitory ability. The results indicated that low-WMC individuals relative to high-WMC individuals showed worse performance specifically in certain conditions of the conditional go/no-go task. Further analyses showed that increasing the temporal lag/number of intervening items between the previous target and the current lure had a deleterious effect on the performance of the low-WMC group only. The results indicate a relationship between WMC and the ability to selectively update, maintain, and retrieve information, especially in interference-rich conditions. (PsycINFO Database Record (c) 2011 APA, all rights reserved)  相似文献   

14.
Proactive interference (PI) may influence the predictive utility of working memory span tasks. Participants in one experiment (N=70) completed Ravens Advanced Progressive Matrices (RAPM) and multiple versions of operation span and probed recall, modified for the type of memoranda (digits or words). Changing memoranda within- or across-trials released PI, but not doing so permitted PI buildup. Scores from PI-build trials, but not PI-release trials, correlated with RAPM and accounted for as much variance in RAPM as unmodified tasks. These results are consistent with controlled attention and inhibition accounts of working memory, and they elucidate a fundamental component of working memory span tasks. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

15.
The current study investigated the effects of cold pressor stress (CPS) on 2 working memory (WM) tasks differing in the demand they put on maintenance and executive processing. For this purpose 72 healthy young men were exposed either to a stress group or a nonstressful control group. Subsequently, WM performance on the O-Span task (Turner & Engle, 1989) and the digit span task was assessed. Salivary cortisol was measured before and 2 times after the treatment as a marker of hypothalamus–pituitary–adrenal (HPA) axis activity. Results revealed a significant performance impairment of the O-Span and the digit span task backward in stressed subjects that correlated negatively with CPS-induced cortisol increases. Digit span forward was neither affected by CPS nor related to the ensuing cortisol increases. These results indicate that acute stress impairs WM performance for tasks requiring executive functions that operate on the stored material but not for WM tasks that only require maintenance. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

16.
Reports an error in "Differential involvement of the dorsal anterior cingulate and prelimbic-infralimbic areas of the rodent prefrontal cortex in spatial working memory" by Michael E. Ragozzino, Spencer Adams and Raymond P. Kesner (Behavioral Neuroscience, 1998[Apr], Vol 112[2], 293-303). Figure 1 (page 295) and Figure 4 (page 299) were printed incorrectly. The corrected figure pages and corresponding captions are provided in the erratum. (The following abstract of the original article appeared in record 1998-01023-003.) The present study examined the effects of quinolinic acid lesions of the dorsal anterior cingulate and prelimbic-infralimbic cortices on spatial working memory and spatial discrimination using go/no-go procedures. All testing occurred in a 12-arm radial maze. In a working memory task, rats were allowed to enter 12 arms for a cereal reward. Three or 4 arms were presented for a 2nd time in a session, which did not result in a reward. In a spatial discrimination task, rats had successive access to 2 different arms. One arm always contained a reward, and the other never contained a reward. Prelimbic-infralimbic lesions impaired spatial working memory but only produced a transient spatial discrimination deficit. Dorsal anterior cingulate lesions did not induce a deficit in either task. These findings suggest that the prelimbic-infralimbic cortices, but not the anterior cingulate cortex, are important in spatial working memory. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

17.
The involvement of monkey (Macaca fuscata) prefrontal cortex (PFC) neurons in motor output decisions was studied by recording single neuron activity during 3 tasks: (a) go-left, go-right, or no-go decisions, (b) operant bar press feeding based on discrimination of food and nonfood, and (c) either delayed matching-to-sample (DMS) or DMS with response delay. Combinations of single neuron responses during the 3 tasks suggested 7 types of PFC neurons that were related to attention, choice, task-unique memory, reward anticipation, laterality, initiation of movement, and suppression of movement. The authors suggest that responses of PFC neurons do not depend on physical properties of the stimuli, but on their behavioral significance. PFC neurons might be important for appropriate behavior in response to external stimuli and internal or motivational factors. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

18.
Previous findings indicate that cholinergic input to the medial prefrontal cortex may modulate mnemonic processes. The present experiment determined whether blockade of muscarinic cholinergic receptors in the rodent anterior cingulate and prelimbic/infralimbic cortices impairs spatial working memory. In a 12-arm radial maze, a working memory for spatial locations task was employed using a continuous recognition go/no-go procedure. Rats were allowed to enter 12 arms for a reinforcement. Of the 12 arm presentations, 3 or 4 arms were presented for a second time in a session that did not contain a reinforcement. The number of trials between the first and second presentations of an arm ranged from 0 to 6 (lags). Infusions of scopolamine (1, 5, and 10 microgram), a muscarinic cholinergic antagonist, into the prelimbic/infralimbic cortices, but not the anterior cingulate cortex, significantly impaired spatial working memory in a lag- and dose-dependent manner. The deficit induced by scopolamine (10 microgram) was attenuated by concomitant intraprelimbic/infralimbic injections of oxotremorine (2 microgram) a muscarinic cholinergic agonist. A separate group of rats was tested on a successive spatial discrimination task. Injections of scopolamine (1, 5, and 10 microgram) into the prelimbic/infralimbic cortices did not impair performance on the spatial discrimination task. These findings suggest that muscarinic transmission in the prelimbic/infralimbic cortices, but not the anterior cingulate cortex, is important for spatial working memory.  相似文献   

19.
Active and passive measures of short-term memory over a large segment of the adult life span were compared. Two hundred twenty-eight volunteers, aged 30 to 99 years, performed the digit span forward and backward task, the Peterson-Peterson task, and a new working memory task in which active manipulation of information is emphasized. Age differences were slight for passive tasks. For the working memory task, significant declines were found between the ages of 60 to 69 and 70+ years. It is suggested that the age differences may be due to a decrease in the flexibility with which processing changes are made. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

20.
Response selection in task shifting was explored using a go/no-go methodology. The no-go signal occurred unpredictably with stimulus onset so that all trials required task preparation but only go trials required response selection. Experiment 1 showed that shift costs were absent after no-go trials, indicating that response processes are crucial for shift costs. In Experiment 2, backward inhibition was absent after no-go trials. Experiments 3 and 4 demonstrated that response selection, rather than execution, causes backward inhibition. All 4 experiments showed effects of preparation time in go trials, suggesting that advance preparation must have also occurred in no-go trials. The authors concluded that inhibition of irrelevant task sets arises only at response selection and that residual shift costs reflect such persisting inhibition. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

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