Ultrastructural changes in liver damage induced by carbon tetrachloride in spontaneously hypertensive rats and Wistar-Kyoto rats

The establishment of a better local area medical centre containing hospitals and clinics is thought to be a very important issue. The medical information system, which should be accepted by both hospitals and clinics, has been studied using graphic user interface (GUI) and a three dimensional structure. Our system files medical records and blood examination data as well as diagnostic images, which may be the first attempt in the world. It has been favourably evaluated by physicians through clinical evaluation.     

Improving the human-computer interface: a human factors engineering approach

Human factors engineering involves the application of information about human behavior and characteristics in the design and testing of products, systems, and environments. A computing system's interface is developed on the basis of potential users' capabilities and limitations, the users' tasks, and the environment in which those tasks are performed. When human factors engineers work with users, subject-matter experts, and developers to design and test a system, they analyze and document users' tasks and requirements and develop prototype designs. Usability studies are conducted and user errors are analyzed to identify problems and develop recommendations for improving the human-computer interface.     

采空区三维可视化集成系统CAD交互接口研发

utoCAD软件作为目前世界上应用最广泛的工程与研究绘图平台之一,在矿业领域具有重要的应用价值。为完善自主研发的采空区三维建模可视化集成系统的功能,进一步提高其应用价值,在分析AutoCAD通用dxf格式文件的数据储存结构和总结不同图元要素数据存储规律的基础上,开发了采空区三维建模可视化集成系统的CAD数据接口,实现了集成系统对采空区扫描点云模型、空区剖面和三角网格实体模型dxf文件的数据读取以及采空区三维点云模型、空区剖面和三角网格实体模型dxf文件的自动生成。实用结果表明,所开发的软件接口成功地实现了集成系统与AutoCAD的数据对接,从而为矿山开展采空区周边相关开采工程的设计带来极大的方便,也为其他CAD接口技术的研发提供有益借鉴。     

Approaches to antiviral chemotherapy for acute respiratory infections

This paper describes a telemedicine system for diabetic patients management, presenting its architecture, the technical solutions adopted and the methodologies on which it is based. The system, designed to provide decision support in a distributed environment, is composed of two modules, a Patient Unit and a Medical Unit, connected by telecommunication services. We outline how the two modules can interact to perform an effective monitoring and a cooperative control of glucose metabolism. In particular, we detail the data analysis tasks performed by the two units and how the results are exploited to assist patients and physicians in revising and adjusting the therapeutic protocol. We will finally describe the current prototypical implementation of the system that uses HTTP as the communication protocol and HTML pages as the graphical user interface.     

Developing a Web-Based System for Large-Scale Environmental Hydraulics Problems with Application to Oil Spill Modeling

Oil spill models are used for decision making during emergencies, contingency planning, and risk assessment. Many of these oil spill models are desktop based. A typical desktop model system is served by an input and output interface to communicate with the user. In a desktop model system, all components reside in the user’s computer. The development of a Web-based model system (Web-CDOG) for large-scale environmental hydraulics problems with an application to oil spill modeling is presented in this paper. The Web-CDOG provides a number of advantages and features that are not available through a desktop system. It helps users to access the model, improves user-developer communication, gives the user access to distributed data, restricts some user access to data (e.g., direct transfer of data from third party sites to the model system without allowing user access), classifies users with different levels of accessibility, and allows multiple users to access the same data. Other examples where a similar Web-based system could be useful include modeling sediment plumes and deepwater oil well blowouts.     

基于图像特征的嵌入式大包下渣检测方法

通过对现有大包下渣检测系统的分析,提出了一种基于图像特征的嵌入式下渣检测方法,阐述了系统嵌入式架构及具体实现方法.该方法以DSP为下位机系统的核心硬件平台,由FPGA与DSP组成的下位机系统将摄像头采集到的模拟图像转换成数字图像,同时进行平均灰度变化与结构相似度的图像特征提取与分析,再经HPI通信模块将处理后的数据发送...     

浅析以太网与web技术在铝电解工业控制系统中的应用

阐述了在铝电解工业控制系统中通过采用以太网和web技术进行数据整合的方法,通过节点服务器的架设实现公司内四级网络的物理连通,再使用数据库编程和.NET技术开发应用程序,制作统一的用户界面和综合数据报表,并根据管理人员的需求对数据进行深度挖掘和处理,有效缩短了管理人员获取生产相关数据的时间,为铝电解生产管理人员提供一个便捷、高效、实用的数据分析平台。     

Development of a Virtual Reality Structural Analysis System

This paper discusses the development of virtual structural analysis program (VSAP). This is a virtual environment (VE) based structural analysis system developed through a collaborative effort between the School of Architecture + Design and the Department of Computer Science at Virginia Polytechnic Institute and State Univ. (Virginia Tech). The VSAP was developed by linking a visualization routine using the simple VE library and a structural analysis software, the PC-SAP4. Details of the design of four user interfaces for the VSAP are presented. These user interfaces are: the immersive pen and tablet interface, the desktop interface, the portable immersive interface, and the cave automatic VE immersive interface. Usability studies for each interface were conducted. Results of these studies indicated that the users of VSAP were highly satisfied with the experience. In addition, all the developed interfaces were found to be successful for their specific application.     

精密铜管拉拔智能化配模系统的设计研究

传统的拉拔模具库配模过程存在过度依赖人工操作和经验、信息更新难度大、配模效率低等问题,本文设计和开发了一套面向企业模具库的智能化信息管理系统。此系统运用了先进的 Spring Boot、Vue 和Hibernate 技术框架,用户对 Vue 编写的前端界面进行操作,前端界面嵌入拉拔算法,后端 Spring Boot 架构实现信息接收请求并处理,处理值反馈到前端与用户交互,并通过 Hibernate 技术将模具信息封装、更新完保存到数据库。此外,通过外模和游芯管理模块、配模工作台模块、借模登记表和归还登记表四个主要模块实现以上架构设计。实践证明,该系统的界面友好、运行稳定,能有效提高拉拔模具库管理效率,保证了铜管生产质量。     

Cognitive science and military training.

Discusses how the massive scale and diversity of training needs in the military render it an enterprise that offers extensive opportunity for the application of cognitive science. Training in maintenance, in tactics, and in piloting or control of aircraft present several issues of interest to cognitive scientists. Four recently developed military training systems illustrate the potential for cognitive science to improve military training. These systems include a family of memorization games based on semantic networks; a simulator for steam propulsion plants with a graphic, schematic student interface; a system for training in problems of relative motion that provides explicit representations of spatial concepts and problem-solving procedures; and a method of building a new cognitive skill for air-intercept control based on principles for the development of automaticity. These systems illustrate the importance of making relevant knowledge concrete and explicit, of using problem-solving contexts for instruction in basic principles, and of careful management of information processing during learning. (28 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

基于红外热成像原理的嵌入式下渣检测方法

通过对现有转炉下渣检测系统的分析,提出了一种基于红外热成像原理的嵌入式下渣检测方法,介绍了红外热成像技术原理,阐述了系统嵌入式架构及具体实现方法。该方法通过红外热像仪采集连续钢流图像,结合嵌入式系统技术,利用数字信号处理器(DSP)对采集到的钢流图像数据根据钢水与钢渣在远红外区的热辐射率不同进行特征信号提取与处理,再经DSP的主机并行接口(HPI)将处理后的图像数据发送给ARM处理器,最后采用图形用户接口MiniGUI设计了嵌入式环境下的图形用户界面,实现对转炉出钢过程中钢流状态的实时监控。现场试验表明:该方法成本低,对现有设备改造小,提高了挡渣效果,较好满足了钢水炉外精炼的要求。     

Influence of transducer frequency on Doppler microemboli signals in an in vivo model

The purpose of this study was to apply virtual reality technology to spiral computed tomographic (CT) angiogram images in a rabbit model of atherosclerosis and to correlate the images with histopathologic evaluation of the aorta. Image data were transferred to the virtual endoscope system in a graphics workstation. "Virtualized angioscopy" includes an interactive graphic user interface, which controls the viewpoint, the direction of the observation, and rendering and navigation functions. The virtual angioscopy system demonstrated irregularities of the luminal surface of the ascending aorta and a smooth luminal surface in the descending aorta. These observations were correlated with histopathologic findings. The results of this study indicate that the potential and real benefits of virtualized angioscopy far outweigh several technical limitations.     

Sculpting proteins interactively: continual energy minimization embedded in a graphical modeling system

We describe a new paradigm for modeling proteins in interactive computer graphics systems--continual maintenance of a physically valid representation, combined with direct user control and visualization. This is achieved by a fast algorithm for energy minimization, capable of real-time performance on all atoms of a small protein, plus graphically specified user tugs. The modeling system, called Sculpt, rigidly constrains bond lengths, bond angles, and planar groups (similar to existing interactive modeling programs), while it applies elastic restraints to minimize the potential energy due to torsions, hydrogen bonds, and van der Waals and electrostatic interactions (similar to existing batch minimization programs), and user-specified springs. The graphical interface can show bad and/or favorable contacts, and individual energy terms can be turned on or off to determine their effects and interactions. Sculpt finds a local minimum of the total energy that satisfies all the constraints using an augmented Lagrange-multiplier method; calculation time increases only linearly with the number of atoms because the matrix of constraint gradients is sparse and banded. On a 100-MHz MIPS R4000 processor (Silicon Graphics Indigo), Sculpt achieves 11 updates per second on a 20-residue fragment and 2 updates per second on an 80-residue protein, using all atoms except non-H-bonding hydrogens, and without electrostatic interactions. Applications of Sculpt are described: to reverse the direction of bundle packing in a designed 4-helix bundle protein, to fold up a 2-stranded beta-ribbon into an approximate beta-barrel, and to design the sequence and conformation of a 30-residue peptide that mimics one partner of a protein subunit interaction. Computer models that are both interactive and physically realistic (within the limitations of a given force field) have 2 significant advantages: (1) they make feasible the modeling of very large changes (such as needed for de novo design), and (2) they help the user understand how different energy terms interact to stabilize a given conformation. The Sculpt paradigm combines many of the best features of interactive graphical modeling, energy minimization, and actual physical models, and we propose it as an especially productive way to use current and future increases in computer speed.     

RNA secondary structure as a reusable interface to biological information resources

The dissemination of biological information has become critically dependent on the Internet and World Wide Web (WWW), which enable distributed access to information in a platform independent manner. The mode of interaction between biologists and on-line information resources, however, has been mostly limited to simple interface technologies such has hypertext links, tables and forms. The introduction of platform-independent runtime environments facilitates the development of more sophisticated WWW-based user interfaces. Until recently, most such interfaces have been tightly coupled to the underlying computation engines, and not separated as reusable components. We believe that many subdisciplines of biology have intuitive and familiar graphical representations of knowledge that can serve as multipurpose user interface elements. We call such graphical idioms "domain graphics". In order to illustrate the power of such graphics, we have built a reusable interface based on the standard two dimensional (2D) layout of RNA secondary structure. The interface can be used to represent any pre-computed layout of RNA, and takes as a parameters the sets of actions to be performed as a user interacts with the interface. It can provide to any associated application program information about the base, helix, or subsequence selected by the user. We show the versatility of this interface by using it as a special purpose interface to BLAST, Medline and the RNA MFOLD search/compute engines. These demonstrations are available at: http://www-smi.stanford.edu/projects/helix/pubs/ gene-combis-96/     

Major issues in user interface design for health professional workstations: summary and recommendations

Lack of good user interfaces has been a major impediment to the acceptance and routine use of health-care professional workstations. Health-care providers, and the environment in which they practice, place strenuous demands on the interface. User interfaces must be designed with greater consideration of the requirements, cognitive capabilities, and limitations of the end-user. The challenge of gaining better acceptance and achieving widespread use of clinical information systems will be accentuated as the variety and complexity of multi-media presentation increases. Better understanding of issues related to cognitive processes involved in human-computer interactions is needed in order to design interfaces that are more intuitive and more acceptable to health-care professionals. Critical areas which deserve immediate attention include: improvement of pen-based technology, development of knowledge-based techniques that support contextual presentation, and development of new strategies and metrics to evaluate user interfaces. Only with deliberate attention to the user interface, can we improve the ways in which information technology contributes to the efficiency and effectiveness of health-care providers.     

An NMR assignment module implemented in the Gifa NMR processing program

MOTIVATION: Peptide and protein structures are determined daily using NMR spectroscopy. Assignment of the NMR spectra is an important step within the procedure and is usually the limiting one. Computer-aided assignment tools should be user friendly with open architecture to communicate with other programs involved in the structure determination. RESULTS: Here we present an interactive NMR assignment module which provides numerous graphic tools for the user. The module is composed of a database management system-handling peaks, spins and spin-systems. The assignment information is maintained as a set of interrelated associative arrays, which serve as generic high-level data structures. The module is developed in the macro language embedded in the Gifa NMR processing program (Pons et al. , J. Biomol. NMR, 8 , 445-452, 1996). This provides the user with a consistent interface, a set of sophisticated tools, and an easily extendible and customizable environment. AVAILABILITY: The program is available on request from the authors. The Gifa package can be accessed at: ((http://www.cbs. univ-montp1.fr/GIFA)) CONTACT: Marc-Andre.Delsuc@cbs.univ-montp1.fr     

Complete nucleotide sequence of HTLV-II isolate NRA: comparison of envelope sequence variation of HTLV-II isolates from U.S. blood donors and U.S. and Italian i.v. drug users

Seven cardiac electrophysiology stimulators from four manufacturers (Biotronik, Bloom, Digitimer and Medtronic) in common current use are reviewed. The stimulators differ in the features provided and the design adopted to achieve these features. The number of output channels ranges from one to four, the number of extra-stimuli available ranges from two to six, and these can be delivered as a variety of sequences. Some of the stimulators (Digitimer and Bloom) are modular while others (Biotronik and Medtronic 532 series) are of an integrated design comprising a single physical unit. The design of the Medtronic EP-2 has both integrated and modular characteristics. The features of the stimulators associated with input, output, control and the user interface are specifically reviewed. The features are also compared against the published recommendations of the American Heart Association. In addition, a summary of stimulator user comments from a number of electrophysiology centres is presented. All of the stimulators fulfil, or are close to fulfilling, basic electrophysiological requirements, but some provide more complex facilities such as would be required by specialist centres.     

BioViews: Java-based tools for genomic data visualization

Visualization tools for bioinformatics ideally should provide universal access to the most current data in an interactive and intuitive graphical user interface. Since the introduction of Java, a language designed for distributed programming over the Web, the technology now exists to build a genomic data visualization tool that meets these requirements. Using Java we have developed a prototype genome browser applet (BioViews) that incorporates a three-level graphical view of genomic data: a physical map, an annotated sequence map, and a DNA sequence display. Annotated biological features are displayed on the physical and sequence-based maps, and the different views are interconnected. The applet is linked to several databases and can retrieve features and display hyperlinked textual data on selected features. In addition to browsing genomic data, different types of analyses can be performed interactively and the results of these analyses visualized alongside prior annotations. Our genome browser is built on top of extensible, reusable graphic components specifically designed for bioinformatics. Other groups can (and do) reuse this work in various ways. Genome centers can reuse large parts of the genome browser with minor modifications, bioinformatics groups working on sequence analysis can reuse components to build front ends for analysis programs, and biology laboratories can reuse components to publish results as dynamic Web documents.     

基于TMN的电力通信网络管理的研究

分析了现有网络管理体系结构的特点，确定了TMN网络管理体系在研究中的主导地位，在需求分析的基础上确立了电力通信网络管理系统的设计原则，讨论了基于TNM的电力通信网络管理系统的开发方法和过程，利用面向对象方法设计了电力通信网络中被管对象的模型，提出了一种综合网管系统的方案。完成了结构设计、管理层次设计、应用功能设计。