共查询到18条相似文献,搜索用时 187 毫秒
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用人大肠癌细胞株HR-8348对激光光敏剂藻蓝蛋白(Phycocyanin)和蚕砂卟啉(CPD4)作光动力学治疗,MTT法测定结果.在含有藻蓝蛋白100μg/ml,50μg/ml,25μg/ml的1640培养液处理大肠癌细胞,采用波长630nm的铜泵染料激光照射(12J/cm2)后,测定细胞生存率分别为22.1%,37.6K,89.7K,各组间P值均小于0.001.同样方法蚕砂卟啉含有10μg/ml,5μg/ml,2.5μg/ml测得细胞生存率分别为20.1%,25.9%,31.5%。MTT法快速,简便,可用于多种光敏剂的筛检试验. 相似文献
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新型四酰胺基铝酞菁的制备及其在体光动力抗癌活性研究 总被引:3,自引:1,他引:3
为寻求在红光区具有良好光动力治疗(PDT)抗癌活性的新型四取代铝酞菁光敏剂,以4-硝基邻苯二甲酸为原料,用苯酐尿素法合成了四氨基铝酞菁(TAAIPc)、四乙酰胺基铝酞菁(TAcAAIPc)、四丙酰胺基铝酞菁(TPrAAIPc)和四丁酰胺基铝酞菁(TBuAAIPc)。表征了所得产物的结构,测试了其荧光光谱和急性毒性;并在输出波长532nm下测定了其光动力抗癌活性。结果表明,所得的酰胺基取代系列铝酞菁对小鼠无明显毒性。当注射剂量为20mg/kg时,上述四种铝酞菁光敏剂对小鼠S180实体瘤的抑瘤率分别为44.96%,45.87%.45.62%和48.65%,差别不明显。加大剂量至40mg/kg时,抑瘤率依次为39.16%,42.81%,40.56%和51.82%。在此剂量下,四丁酰胺基铝酞菁表现出较高的光动力治疗抗癌活性。 相似文献
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林礼煌 《激光与光电子学进展》1998,35(4):25-26
日本科学技术振兴事业团(原新技术事业团)的山本量子波动规划与日本电信电话(株式会社)的基础研究所,共同开发出极微弱光的检测技术。能够测量平均功率10fw(1fW=10-15W)的光脉冲列和脉冲形状,其时间分辨率为5fs。规划负责人是斯坦福大学教授兼日本电信电话基础研究所特别研究员山本喜久。测定装置如图所示,测定方法是零拍检波法之一。首先,稳定的激光脉冲从图的左侧入射,实验所用的是波长为800nm的钛宝石激光。入射光束由分束器分成两路,一路作为零拍检波的本机振荡光,另一路(图中未画出)射向测定样品,形成信号光。信号光… 相似文献
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亚波长周期结构光栅具有传统光栅所不具有的特殊特性。基于矢量衍射理论-耦合波分析法对矩形亚波长光栅的衍射效率进行了理论计算,针对光通信中的1 550nm波长设计了一种基于SOI衬底的亚波长偏振光栅,分析了光栅周期、光栅深度、占空比和光栅结构的变化对其偏振特性的影响。仿真结果表明,当光栅的周期为960nm,槽深为230nm,占空比为24%时,可使TM模式的透射率大于95%,TE模式的透射率小于5%,且矩形的光栅结构相对于三角形和圆形的光栅结构具有更好的偏振性能,可有效用于光开关、光隔离器、激光器、光探测器等半导体光电子器件。 相似文献
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皮肤对光的反射、透射和吸收规律的初步实验研究 总被引:10,自引:0,他引:10
实验研究表明:(1)人体皮肤对光的反射不仅仅发生在皮肤表面,还发生在皮肤以下的组织层;(3)在400~800nm之间,人体对光的反射比曲线吸收峰与人血对光的透射比曲线的吸收峰相同;(3)在400~800nm之间,皮肤或皮加皮下组织的反射比和透射比曲线具有基本相似的变化趋势。 相似文献
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Infrared silver halide fibers were studied concerning the optical degradation induced by photodarkening. Infrared transmittance decreased notably in the shorter wavelength (near-infrared) region by the exposure to ultraviolet (UV) or visible light below a wavelength of ~600 nm. Black paint was tentatively coated on the unclad fiber for photodarkening protection, but the infrared transmittance of the fiber decreased heavily due to the evanescent wave absorption by the paint. To reduce this absorption loss, a fluorocarbon polymer was coated between the fiber core and the black paint. Consequently, efficient transmission was realized in the infrared region except for the 7-10-μm wavelength range, where the fluorocarbon polymer has a strong absorption band. In the 2-7-μm wavelength range, the fiber that was heated at 100°C in the polymer coating process exhibited higher transmittance than the original uncoated fiber. No optical degradation of the coated fiber was observed, even after irradiation with UV light for a period of 70 h 相似文献
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常规的半导体紫外探测器波长响应范围宽,而紫外光的应用具有较强的波长选择性,如320nm波段的紫外光在医学方面有重要的应用,因此,具有高波长选择性的紫外探测器的研制有重要意义。文章采用GaN基p-i-n探测器结构,通过在p区覆盖银纳米薄膜作为欧姆接触层和波长选择透射层,成功制备了对320nm波段紫外光高选择性探测的紫外探测器,器件性能如下:70nm银层的紫外光透射率峰值超过30%,器件在-5V偏压下的暗电流为10-12 A量级,响应峰值为0.06A/W,响应峰发生在325nm处,光谱响应峰半高宽约30nm。 相似文献
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为了减少和避免激光和微波辐射眼损伤,设计研制了防激光、防微波、激光探测告警为一体的多功能防护镜。该防护镜由特定功能的光学部件和光电子模块组成,包括多功能复合防护镜片、镜架和激光探测报警系统。进行了多功能防护镜复合技术研究和防护性能测试。结果表明,该防护镜在激光波长532nm,1064nm,790nm,840nm的光密度为4.0~7.28;可见光积分透过率为18.7%;微波衰减大于20dB;报警系统在532nm,1064nm和840nm激光波长能提供自动检测和声光报警,报警器的探测灵敏度为10-7/cm2;该防护镜可承受1g质量、300m/s~400m/s速率的钢制球形破片的冲击;防护镜总质量小于200g,该防护镜防护波段宽、对激光和微波的衰减倍率高、防护角大、可见波段透光性好、可分体和组合使用、体积小、重量轻、便于佩戴、适用于个人佩戴防护和光电传感器的防护。在现代光学实验和各种激光与微波作业环境,以及反恐和公共安全中是不可缺少的防护器材。 相似文献
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The display based on up-conversion of near infrared light is a novel display. To improve the screen luminance and avoid leakage of infrared light, two multilayer interference filters are designed on the screen of the display. One is called the LP filter, having low transmittance for visible light between 400 and 800 nm, and high transmittance for infrared light between 800 and 1000 nm; the other is called the SP filter with opposite characteristics to those of the LP filter. Layer-symmetric films are used to design the filters and the conjugate gradient method is used to optimise the design. The LP and SP filters obtained have good characteristics within the whole wavelength bandwidth between 400 and 1000 nm and the incident angle range 0-20/spl deg/. The manufacturing tolerances on film thickness and refractive index are reasonably large. 相似文献
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为了研究常温状态下石英旋光晶体透射谱线,根据石英旋光晶体透射比的理论分析,采用UV-3101PC分光光度计实际测试,得到了300nm~1500nm波长范围特定厚度石英旋光晶体的连续透射谱线,并对所得谱线与理论结果进行了对比分析。结果表明,400nm以内由于石英晶体吸收比较明显,从而峰值透射比低于50%,由于旋光率随波长变化率很大,谱线周期很小;400nm~800nm之间峰值透射比60%,透射谱线的周期性及峰值个数受晶体厚度影响明显;波长大于1000nm时,由于旋光率随波长变化率很小从而谱线周期很大,并且谱线不规则,与石英材料波长选择吸收有关。 相似文献
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Improvement of the luminous intensity of light-emitting diodes by using highly transparent Ag-indium tin oxide p-type ohmic contacts 总被引:1,自引:0,他引:1
J.-O. Song Dong-Seok Leem Joon Seop Kwak Y. Park S.W. Chae Tae-Yeon Seong 《Photonics Technology Letters, IEEE》2005,17(2):291-293
We have investigated Ag-indium tin oxide (ITO) scheme for obtaining high-quality p-type ohmic contacts for GaN-based light-emitting diodes (LEDs). The Ag(1 nm)-ITO(200 nm) contacts exhibit greatly improved electrical characteristics when annealed at temperatures in the range 400/spl deg/C-600/spl deg/C for 1 min in air, yielding specific contact resistances of /spl sim/10/sup -4/ /spl Omega//spl middot/cm/sup 2/. In addition, the contacts give transmittance of about 96% at 460 nm, which is far better than that of the conventionally used oxidized Ni-Au contacts. It is shown that the luminous intensity of blue LEDs fabricated with the Ag-ITO contacts is about three times higher than that of LEDs with oxidized Ni-Au contacts. This result strongly indicates that the Ag-ITO scheme can serve as a highly promising p-type ohmic contact for the realization of high brightness near ultraviolet LEDs. 相似文献
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Chen W.S. Shei S.C. Chang S.J. Su Y.K. Lai W.C. Kuo C.H. Lin Y.C. Chang C.S. Ko T.K. Hsu Y.P. Shen C.F. 《Electron Devices, IEEE Transactions on》2006,53(1):32-37
Nitride-based flip-chip (FC) light-emitting diodes (LEDs) emitting at 465 nm with Ni transparent ohmic contact layers and Ag reflective mirrors were fabricated. With an incident light wavelength of 465 nm, it was found that transmittance of normalized 300/spl deg/C rapid thermal annealed (RTA) Ni(2.5 nm) was 93% while normalized reflectance of 300/spl deg/C RTA Ni(2.5 nm)/Ag(200 nm) was 92%. It was also found that 300/spl deg/C RTA Ni(2.5 nm) formed good ohmic contact on n/sup +/ short-period-superlattice structure with specific contact resistance of 7.8/spl times/10/sup -4/ /spl Omega//spl middot/cm/sup 2/. With 20-mA current injection, it was found that forward voltage and output power were 3.15 V and 16.2 mW for FC LED with 300/spl deg/C RTA Ni(2.5 nm)/Ag(200 nm). Furthermore, it was found that reliabilities of FC LEDs were good. 相似文献