Disaggregating parental depression and family stress in assessing families of children with developmental disabilities: a multisample analysis

Thymic nurse cells are defined in vitro as multicellular complexes of epithelial cells and thymocytes. Although these structures have been implicated in the intrathymic differentiation of thymocytes, little is known about the biology of this cell complex and about the occurrence of the cells in the thymus in situ. Therefore, to clarify the matter, in this review we have presented characteristics of epithelial cells capable of forming complexes with thymocytes, in light of the literature data and the experience of the authors. The structure of cells within the complexes allowed us to distinguish three types of thymic nurse cells. Three-dimensional reconstruction of the thymus and observations employing TEM and SEM demonstrated the presence of distinct types of complexes in various topographic regions of the thymus. Where possible, the functional relevance of the morphological data was analyzed.     

Posttraumatic stress, family functioning, and social support in survivors of childhood leukemia and their mothers and fathers.

Psychological sequelae are examined in 130 former childhood leukemia patients and 155 comparison participants and their parents. The major dependent variables are symptoms of anxiety and posttraumatic stress, family functioning, and social support. Multivariate analyses of covariance indicated significantly more posttraumatic stress symptoms in mothers and fathers of childhood leukemia survivors (p?     

Psychological adjustment of mothers of children and adolescents with sickle cell disease: the role of stress, coping methods, and family functioning

Assessed the psychological adjustment of 78 mothers of children and adolescents (7-17 years of age) with sickle cell disease. Support was provided for a transactional stress and coping model in delineating the processes associated with maternal adjustment. In particular, poor maternal adjustment was associated with use of palliative coping methods and high levels of stress related to daily hassles. Variables of the model accounted for 55% of the variance in maternal psychological distress.     

Parenting stress and social support of mothers who physically abuse their children in Hong Kong

Thirty-seven identified abusive mothers were matched on demographic and socioeconomic parameters with a known nonabusive comparison sample in order to examine the role of parenting stress and maternal social support. The mothers were assessed using a personal (demographic) questionnaire, the Parenting Stress Index (PSI), and the Maternal Support Index (MSSI). Demographic data showed that the two groups were comparable on all variables except abusive mothers had significantly more children (p = .01). Abusive mothers showed significantly more stress on total PSI scores (p = .005), as well as in all three of the subjects: Child Domain (p = .007) Parent Domain (p = .02), and Life Stress (p = .016). Abusive mothers scored lower in all seven items on the MSSI. The difference was significant on the MSSI as a whole (p = .007) and on four subsets: number of people to count on in time of need (p = .02), perceived neighborhood support (p = .04), satisfaction with spousal relationship (p = .01), and degree of community involvement (p = .03). The greatest percentage (74.32%) of correct predictions of child abuse was achieved by combining the number of children, the Life Stress Scale and the MSSI. Implications for future research are discussed.     

Stress appraisal and social support of Chinese mothers of adult children with mental retardation

Thirty Chinese mothers of adult children with moderate to severe mental retardation were interviewed to explore the source and nature of their stress and social support. Results revealed child-related and parent-related stress specific to these mothers. The most common stressors were future planning and behavioral problems of the target offspring. Mothers received tangible, emotional, and informational support mainly from family members and training center staff. Some evidence was also found for the optimal-matching model of stress appraisal and social support. Regardless of the duration of stress, all forms of support were perceived as equally useful for uncontrollable stress, whereas tangible support was regarded as more useful than informational support for controllable stress.     

The intergenerational costs of parental social stressors: academic and social difficulties in early adolescence for children of young mothers

Social stressors embedded in parents' occupational and family roles have been shown to have effects on family interaction and the cognitive and emotional development of young children. Here we consider whether these patterns also hold for children in early adolescence. We study 1,158 10 to 14-year-old children born to the early childbearers among the female respondents of the National Longitudinal Survey of Youth cohort. We find that both poor quality of parental employment and low quality of mothers' relationships with their partners have adverse effects on the cognitive stimulation and maternal warmth children receive; living in informal unions is also associated with poorer parent-child interaction. These family interaction patterns in turn both buffer the effects of stressful family conditions and shape academic and behavior outcomes directly. Some work and family conditions interact in their effects: In particular, single mothering has less adverse effects on cognitive stimulation and behavior problems when mothers are employed in occupations providing higher complexity. The effects of current conditions are diminished but seldom eliminated when we control for possible selection effects by using data from earlier waves to control for earlier levels of child problems. These findings suggest that current parental social stressors continue to have consequences for both academic and behavioral outcomes during early adolescence.     

Family functioning and social support in the adaptation of caregivers of children with sickle cell syndromes

OBJECTIVE: To examine moderating effects of family functioning and social support on the relationship of child-related stressors to caregivers' psychological adaptation in a sample of caregivers of children with a chronic illness. METHOD: Participants were 67 caregivers of children and adolescents with sickle cell syndromes. We conducted MANOVAs and subsequent effect size calculations to determine if family functioning would buffer the effects of caring for difficult-to-manage children with this illness. RESULTS: Findings supported a moderator effect of family functioning on the association of children's externalizing behavioral problems to caregivers' symptoms of hostility. Greater levels of cohesive and adaptive family functioning buffered the potential detrimental effects of caring for children perceived as hard to manage. No significant associations were obtained between measures of caregivers' psychological adaptation and the severity of their children's disease. CONCLUSIONS: We make recommendations for family systems interventions, particularly for caregivers of children with behavior problems.     

Adulthood functioning: the joint effects of parental alcoholism, gender and childhood socio-economic stress

The popular literature has publicized the adjustment difficulties of adult children of an alcohol-dependent parent (ACOAs); however, empirical studies do not provide consistent support. We examined the impact of parental alcoholism, degree of childhood socio-economic stress and gender on three broad categories of adulthood functioning (psychopathology, socio-economic attainment and marital stability). These effects were investigated with a heterogeneous sample of 400 men and 226 women participating in studies at the University of Michigan Alcohol Research Center. Parental alcoholism and childhood socio-economic stress exerted significant independent effects on most adulthood functioning measures. Men and women differed substantially only on socio-economic attainment measures, and effects of parental alcoholism and childhood economic stress on men and women were generally similar. For marital stability, parental alcoholism and childhood socio-economic stress interacted. These results suggest that researchers who study the impact of family history for alcoholism on psychological functioning should consider other aspects of the family of origin that promote wellbeing. In addition, results of this study point to the need for more research on gender differences, protective factors that promote good adjustment and outcome measures reflecting general life adaptation.     

Occupational stress, social support, and depression.

Developed a model of occupational stress, social support, locus of control, and depression among family physicians. 210 family physicians (average age 48 yrs) were administered measures of occupational stress, social support, locus of control, and depression. The hypothesized model was evaluated using structural equation models (LISREL). Results indicate that occupational stress exerted a direct effect on depression. This relationship was moderated directly by family social and emotional support and indirectly by the influence of locus of control on family social support. Support from peers was not significantly related to depression. Findings suggest that individuals with a strong sense of personal control also possess beneficial support systems in the presence of stressful situations. (58 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The effects of inclusion on the social functioning of students with learning disabilities

The purpose of this study was to provide data on the social functioning (i.e., the degree of peer acceptance, self-concept, loneliness, and social alienation) of students in second, third, and fourth grade who participated in an inclusive classroom for an entire year. The social functioning of students identified as learning disabled (LD; n = 16), low achieving (LA; n = 27), and average/high achieving (AHA; n = 21) was assessed at the beginning and end of the school year. The students with LD were less well liked and more frequently rejected than AHA students. Although students' overall self-worth did not differ by achievement group, the students with LD demonstrated significantly lower academic self-concept scores. The students with LD did not differ on ratings of loneliness, and they demonstrated increases in the number of within-class reciprocal friendships from fall to spring. Discussion focuses on the effects of inclusion on the social functioning of students with LD.     

Victimization, social support, and psychosocial functioning among children of same-sex and opposite-sex couples in the United Kingdom.

To further develop an understanding of psychological and social functioning of children raised by lesbian couples, the authors compared 18 students ages 12-16 raised in families led by female same-sex couples, who were identified from a large school-based survey, with 18 matched students raised by opposite-sex couples and the general student sample. Comparisons were made on factors including victimization, social support, and psychological functioning. Results indicate that those students raised by female same-sex couples did not differ significantly from those raised by opposite-sex couples or the general student sample in terms of reports of victimization, psychological functioning, experience of common adolescent concerns, or prospective use of support outlets provided by family and peers. However, children of same-sex couples reported significantly less likelihood of using school-based support than did children of opposite-sex couples or the general student sample. Findings indicate the need for school administrators, teachers, and psychologists to be knowledgeable of and provide appropriate support and resources for these children. Additional implications for research and application are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Perceived social support, psychological adjustment, and functional ability in youths with physical disabilities.

Objective: To examine the relationship between perceived social support and psychological adjustment and functional ability in youths with physical disabilities. Participants: Thirty-seven youths with neuromuscular disease and 33 with spina bifida. Measures: Demographic and disability-related questions, Child Health Questionnaire, Functional Disability Inventory, and Multidimensional Scale of Perceived Social Support. Results: Social support from family, but not from friends, was significantly associated with better psychological adjustment. Significant interactions emerged between family support and age, as well as between friend support and gross motor functioning, in the prediction of functional ability. Conclusions: Social support appears to play an important role in psychological adjustment and functional ability in this population, and the nature of this role may be moderated, to some extent, by age and gross motor functioning. Future research and clinical implications are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Demographics, family history, premorbid functioning, developmental characteristics, and course of patients with deteriorated affective disorder

OBJECTIVE: This exploratory study examined the characteristics of a group of unusual and previously undescribed patients with major affective disorder who not only had been continuously symptomatic for prolonged periods of time but were also so functionally impaired that they required years of continuous care in psychiatric facilities or by family members. METHOD: Twenty-seven inpatients with major mood disorders and 29 inpatients with schizophrenia were recruited from a large state hospital; 27 outpatients with major mood disorders were recruited from an affiliated outpatient facility. The research battery included the Structured Clinical Interview for DSM-III-R--Patient Version, the Premorbid Adjustment Scale, and a semistructured interview designed to assess demographic, family history, developmental, and course information. RESULTS: Inpatients with deteriorated affective disorder differed from outpatients with nondeteriorated affective disorder along several important dimensions, including family history of mental illness, birth-related problems, physical disorders in infancy, premorbid functioning, presence of mixed episodes and rapid cycling, and medication non-compliance between hospitalizations. Inpatients with deteriorated affective disorder differed from inpatients with schizophrenia on the Premorbid Adjustment Scale. Patients with bipolar affective disorder differed from those with unipolar disorder on many of the variables associated with deterioration of functioning. CONCLUSIONS: Birth-related problems, physical disorders in infancy, and poor premorbid adjustment in childhood and adolescence appear to play an important role in deterioration of functioning among patients with unipolar depression. Disruption in treatment because of medication noncompliance and the appearance of mixed episodes and rapid cycling are associated with functional decline in bipolar affective disorder. Several characteristics previously considered specific to deterioration of functioning in schizophrenia, such as a high rate of birth complications and poor premorbid adjustment, appear to be associated with functional deterioration among patients with major depression as well.     

Maternal stress induces synaptic loss and developmental disabilities of offspring

Mild prenatal stress affects the serotonergic system in the hippocampus of rat offspring. Pregnant rats were daily exposed to mild stress treatments (consisting of crowding and saline injection) during days 15 to 21 of pregnancy. Their offspring were assessed by a series of biochemical, histological and behavioral tests. On 35 days after birth, 5-hydroxytryptamine (5-HT) level was decreased by 17% (P < 0.05), whereas 5-hydroxyindolacetic acid (5-HIAA) level was increased by 18% (P < 0.05) in the offspring of prenatally stressed rats. The metabolic rate (5-HIAA/5-HT) was increased by 49% (P < 0.01). Synaptic density in the hippocampus of prenatally stressed offspring was also decreased by 32% (P < 0.0001) on postnatal day 35. There was no significant group difference in the spatial learning acquisition test of the Morris water maze; however, in the reversal task, prenatally stressed 5-week old rats spent more time than control animals searching for the platform of the pool. Escape latency in the cued test showed no significant difference. Together with data in our previous studies, that have shown 5-HT to facilitate synapse formation and maintenance in the central nervous system, synaptic loss is suggested to occur in relation to changes of 5-HT system in the hippocampus of prenatally stressed offspring. This may be associated with reported changes in behavior and learning ability in prenatally stressed offspring.     

Perceived social support from friends and family and psychosocial functioning in bisexual young adult college students.

In this study, the authors investigated the degree to which perceived social support was associated with depression, life satisfaction, and internalized binegativity in a sample of 210 bisexual young adult college students. Two types of social support (general and sexuality specific) and 2 sources of social support (family and friends) were examined. Participants were recruited from the electronic mailing lists of organizations serving lesbian, gay, bisexual, and transgender students on 32 university campuses, and data were gathered via an Internet survey. Results indicated that general social support was most predictive of depression and life satisfaction, whereas sexuality-specific support was most predictive of internalized binegativity. Both family support and friend support contributed to the prediction of each of the outcome variables. Although it was expected that the link between friend support and positive adjustment would be strongest at low levels of family support, none of the interactions between friend and family support was statistically significant. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The role of parental and extrafamilial social support in the psychosocial adjustment of children with a chronically ill father

The relationships among illness stress, perceived support, and child psychosocial adjustment were examined for children living with a chronically ill father. Participants included fathers, mothers, and one child from 53 families in which the father had hemophilia and, in some cases, was HIV seropositive. Objective indicators of severity of illness and subjective measures of the physical and psychological impact of illness were used as sources of children's stress. Results indicated that the impact of illness, but not the severity of illness itself, related to child psychosocial adjustment. Main effects were observed for parental support on child- and parent-reported internalizing problems and stress-buffering effects were obtained for parental support and extrafamilial support on parent-reported internalizing problems. Parental support also demonstrated a stress-buffering effect for child-reported depression. Assessment and intervention implications for behavioral clinicians and researchers are discussed.     

Quality of social support and associated social and psychological functioning in women with rheumatoid arthritis.

Investigated the relationship between health status, social integration, qualitative aspects of social support, and social and psychological functioning in 194 women (aged 21–65 yrs) with rheumatoid arthritis. Ss completed a telephone interview that included measures of these variables. Even after controlling for the influences of current physical limitations and social integration, qualitative dimensions of social support as measured by the Quality of Social Support Scale, a scale developed for this study, explained a significant proportion of the variance in home and family functioning and in depression. This demonstrates the importance of social support to both social and psychological functioning with a chronic, painful, and disabling disease. (PsycINFO Database Record (c) 2010 APA, all rights reserved)