Developmental and social influences on young girls' early problem behavior.

A developing body of research suggests that there are few sex differences in the rate and severity of problem behavior in early childhood, but clear sex differences emerge at about 4 years of age. The authors explore 2 hypotheses to further the understanding of emerging sex differences in problem behavior across the first 5 years of life. The first posits that the change in girls' problem behavior from infancy to school entry represents a channeling of early problem behavior into predominantly internalizing problems as a result of socialization. The second hypothesis is that the change in girls' early problem behavior during the preschool period results from the more rapid biological, cognitive, and social–emotional development of girls relative to boys. The authors review research on the influence of parents, teachers, and peers on girls' behavior from infancy to preschool regarding the first hypothesis, whereas they review studies of sex differences in developmental processes to test the second. They find moderate support for both hypotheses and present a comprehensive theory of girls' developmental psychopathology that integrates social and developmental influences. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Social neuroscience: Understanding the pieces fosters understanding the whole and vice versa.

Social science and neuroscience perspectives represent two ends of a continuum of levels of organization studied in psychology. Human behavior as a whole unfolds at social levels of organization, whereas much of the research in psychology has focused on cognitive and biological pieces of this whole. Recent evidence underscores the complementary nature of social, cognitive, and biological levels of analysis and how research integrating these levels can foster more comprehensive theories of the mechanisms underlying complex behavior and the mind. This research underscores the unity of psychology and the importance of retaining multilevel integrative research that spans molar and molecular levels of analysis. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The biology of human parenting: insights from nonhuman primates

Primate and human parenting have often been viewed as completely emancipated from neuroendocrine influences and primarily dependent on experience, social and cognitive processes. A review of recent findings of primate research on the neurobiological regulation of parental responsiveness, the causes of variability in parenting styles, and the determinants of infant abuse suggests that primate parenting is more sensitive to neuroendocrine mechanisms than previously thought. The findings of primate research can have important implications for human research and encourage the investigation of biological influences on human parenting.     

The relationship between social support and physiological processes: A review with emphasis on underlying mechanisms and implications for health.

In this review, the authors examine the evidence linking social support to physiological processes and characterize the potential mechanisms responsible for these covariations. A review of 81 studies revealed that social support was reliably related to beneficial effects on aspects of the cardiovascular, endocrine, and immune systems. An analysis of potential mechanisms underlying these associations revealed that (a) potential health-related behaviors do not appear to be responsible for these associations; (b) stress-buffering effects operate in some studies; (c) familial sources of support may be important; and (d ) emotional support appears to be at least I important dimension of social support. Recommendations and directions for future research include the importance of conceptualizing social support as a multidimensional construct, examination of potential mechanisms across levels of analyses, and attention to the physiological process of interest. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Molecular and cell biological aspects of neuroendocrine tumors of the gastroenteropancreatic system

Neurons and neuroendocrine cells share a variety of common characteristics. Cell and molecular biological studies in recent years have improved our understanding of physiological and pathophysiological processes such as cellular growth, adhesion, and secretion of neuroendocrine cells. Here we review current findings from the area of basic research and from current clinical research relevant to improving the diagnosis and therapy of neuroendocrine tumors of the gastroenteropancreatic system.     

Loneliness, social isolation, and behavioral and biological health indicators in older adults.

Objective: A number of mechanisms have been proposed through which social isolation and loneliness may affect health, including health-related behavioral and biological factors. However, it is unclear to what extent isolation and loneliness are independently associated with these pathways. The objective of the present analysis was to determine the impact of social isolation and loneliness, individually as well as simultaneously, on health-related behavioral and biological factors using data from the English Longitudinal Study of Ageing (ELSA). Method: Data on health behaviors (smoking and physical activity) were analyzed from 8,688 participants and data on blood pressure, cholesterol, and inflammatory markers were analyzed from over 5,000 of these participants who were eligible for a nurse visit and blood sampling. Loneliness was measured using the short form of the Revised UCLA scale and an index of social isolation was computed incorporating marital status; frequency of contact with friends, family, and children; and participation in social activities. Results: Fewer than 2% of participants reported being lonely all the time, while nearly 7% had the highest possible scores on social isolation. Both social isolation and loneliness were associated with a greater risk of being inactive, smoking, as well as reporting multiple health-risk behaviors. Social isolation was also positively associated with blood pressure, C-reactive protein, and fibrinogen levels. Conclusions: Loneliness and social isolation may affect health independently through their effects on health behaviors. In addition, social isolation may also affect health through biological processes associated with the development of cardiovascular disease. (PsycINFO Database Record (c) 2011 APA, all rights reserved)     

Imaging Race.

Researchers have recently begun to use the tools of neuroscience to examine the social psychological responses associated with race. This article serves as a review of the developing literature in this area. It advances the argument that neuroscience studies of race have the potential to shape fundamental assumptions about race, and the interplay between social and biological processes more generally. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Social and cognitive sources of potential inaccuracy in job analysis.

Although it appears that many assume job analysis information is accurate, there is considerable evidence from other fields to suggest that the types of subjective judgments often involved in job analysis may be subject to systematic sources of inaccuracy. Drawing from the social, cognitive, and industrial-organizational psychology literatures, this review develops a framework that delineates 16 potential sources of inaccuracy in job analysis. This includes such social sources as social influence and self-presentation processes as well as cognitive sources such as limited and biased information processing. For each source of inaccuracy, the relevant literature is first reviewed, its potential operation in the job analysis context is described, and propositions for future research are derived. In addition, the likelihood of these sources of inaccuracy across various job analysis facets are described, concluding with recommendations for research and practice. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

In Genes We Trust: The Biological Component of Psychological Essentialism and Its Relationship to Mechanisms of Motivated Social Cognition.

Three studies analyzed the biological component of psychological essentialism (laypeople's belief that social categories have an underlying nature/natural foundation) as it pertains to mechanisms of motivated social cognition. A new scale assessing the belief in genetic determinism is introduced as a measure of the biological component of essentialism. Results speak to the reliability and validity of the scale and show that essentialist beliefs are associated with basic social-cognitive motives and are also related to processes of stereotyping and prejudice. An experimental study found that rendering essentialist information salient elicits increased levels of prejudice and in-group bias, particularly in persons holding chronic essentialist beliefs. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The emergence of social cognitive neuroscience.

Social cognitive neuroscience is an emerging interdisciplinary field of research that seeks to understand phenomena in terms of interactions between 3 levels of analysis: the social level, which is concerned with the motivational and social factors that influence behavior and experience; the cognitive level, which is concerned with the information-processing mechanisms that give rise to social-level phenomena; and the neural level, which is concerned with the brain mechanisms that instantiate cognitive-level processes. The social cognitive neuroscience approach entails conducting studies and constructing theories that make reference to all 3 levels and contrasts with traditional social psychological and cognitive neuroscientific research that primarily makes reference to 2 levels. The authors present an introduction to and analysis of the field by reviewing current research and providing guidelines and suggested directions for future work. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Levels of analysis and the organization of affect.

This article presents a framework for the organization of affective processes, including the affective traits, moods, and emotions. Section 1 introduces the levels-of-analysis approach, defines the three levels of affect, presents criteria for ordering these levels hierarchically in terms of simple and complex temporally driven processes, and examines the interrelations among the various levels of affect, including an in-depth analysis of affective trait-emotion relationships. Section 2 offers an application of the hierarchical view to research on affect-cognition interactions, including a brief review of affect congruency effects and a discussion of the conceptual and empirical challenges to such research necessitated by consideration of the differences among the levels of affect. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Beyond behaviorism: On the automaticity of higher mental processes.

The first 100 years of experimental psychology were dominated by 2 major schools of thought: behaviorism and cognitive science. Here the authors consider the common philosophical commitment to determinism by both schools, and how the radical behaviorists' thesis of the determined nature of higher mental processes is being pursued today in social cognition research on automaticity. In harmony with "dual process" models in contemporary cognitive science, which equate determined processes with those that are automatic and which require no intervening conscious choice or guidance, as opposed to "controlled" processes which do, the social cognition research on the automaticity of higher mental processes provides compelling evidence for the determinism of those processes. This research has revealed that social interaction, evaluation and judgment, and the operation of internal goal structures can all proceed without the intervention of conscious acts of will and guidance of the process. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Play, aggression, the preschool child, and the family: A review of literature to guide empirically informed play therapy with aggressive preschool children.

Preschool-aged children displaying high levels of aggression repeatedly have been shown to be at significant risk for continued behavior problems and other social and emotional challenges throughout their lifetimes. The present literature review seeks to summarize and integrate findings across the fields of developmental psychology, family studies, child development, and play therapy to inform play therapists' practices with this population. Specifically, findings from research in these fields hold substantial implications for empirically informed ways in which play therapists can include parents within play therapy processes. Affective quality of parent- child interactions emerges as the common theme across all existing literature and is emphasized as a critical focus for play-based therapeutic intervention. Topics for future research by play therapists focusing on this population are suggested. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

A review of sex differences in peer relationship processes: Potential trade-offs for the emotional and behavioral development of girls and boys.

Theory and research on sex differences in adjustment focus largely on parental, societal, and biological influences. However, it also is important to consider how peers contribute to girls' and boys' development. This article provides a critical review of sex differences in several peer relationship processes, including behavioral and social-cognitive styles, stress and coping, and relationship provisions. The authors present a speculative peer-socialization model based on this review in which the implications of these sex differences for girls' and boys' emotional and behavioral development are considered. Central to this model is the idea that sex-linked relationship processes have costs and benefits for girls' and boys' adjustment. Finally, the authors present recent research testing certain model components and propose approaches for testing understudied aspects of the model. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The social impact of majorities and minorities.

Reviews 2 traditional lines of research on social influence processes—research on conformity, which looks at the influence of the majority on a passive minority, and research on innovation, which considers the influence of active minorities on a silent majority. A new theory of social impact is examined that views social influence as resulting from forces operating in a social force field. It proposes that influence by either a majority or a minority will be a multiplicative function of the strength, immediacy, and number of its members. It is suggested that social impact theory offers a general model of social influence processes that integrates previous theoretical formulations and empirical findings and accounts for the reciprocal influence of majorities and minorities. Thus, by viewing social influence as a unitary concept, social impact theory permits comparisons between conformity and innovation and predicts the relative magnitude of their effects. (39 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The social communication model of pain.

Everybody is an expert on pain, by virtue of biological preparedness and personal experience. Unfortunately, this expertise fails large numbers of people, and we must improve our understanding through theoretical and research advances. A vast research-based literature on the nature and management of pain is now available, and there have been dramatic advances in our understanding and management of pain. Nevertheless, there continue to be major problems in the management of severe acute pain and chronic pain. It is argued that a formulation of pain that explicitly focuses upon social factors would more readily address human needs than models that focus upon biophysical and/or psychological factors alone (intrapersonal processes). Although ancient protective biological systems provide for escape and avoidance of pain, evolution of human capacities for cognitive processing and social adaptation necessitate a model of pain incorporating these capabilities (interpersonal processes). The more inclusive and comprehensive social communication model of pain is described and illustrated. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

NMR and CD conformational studies of bradykinin and its agonists and antagonists: application to receptor binding

Most physiological processes are regulated by peptides that perform their functions by interacting with specific receptors on cells. Specific conformations of the peptides are required for correct interactions to take place, and a knowledge of the biologically important conformation is vital for the understanding of biological function. Over the last few years extensive studies using nuclear magnetic resonance and circular dichroism have been carried out on bradykinin (Arg1-Pro2-Pro3-Gly4-Phe5-Ser6-Pro7-Phe8-Arg9) and its antagonists with the objective of developing new drugs to combat severe pathologies associated with its production. In the present review, these techniques for the determination of peptide conformation are reviewed and applied to the study of bradykinin and its antagonists. Modeling of these conformational data in the presence of the B2 receptor or an antibody allows the biologically active conformations to be deduced and these are presented in this review.     

Social comparison and big-fish-little-pond effects on self-concept and other self-belief constructs: Role of generalized and specific others.

Two studies integrate the big-fish-little-pond effect (BFLPE; negative effects of class-average achievement on academic self-concept, ASC), which is based upon educational psychological research, with related social psychological research that is based on social comparison theory. Critical distinctions are the nature of the social comparison processes that are based on generalized-other (class- or school-average) or individual (target comparison classmate) comparisons, and the nature of self-belief constructs that invoke normative (social comparison) or absolute frames of reference. In a large cross-national study (26 countries; 3,851 schools; 103,558 students), school-average ability negatively affected ASC but had little effect on 4 other self-belief constructs that did not invoke social comparison processes. In Study 2 (64 classes; 764 students), 2 sources of social comparison information (class-average achievement and achievement of an individually selected target comparison classmate) each had distinct, substantial negative effects on agency self-beliefs that invoked social comparison processes but not on metacognitive responses that did not invoke these processes. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Urbanization, mental health, and social deviancy: A review of issues and research.

This article reviews the international research literature on the relationship of urbanization, mental health, and social deviancy. Attention is called to the multidisciplinary and multisectoral nature of the topic, and to its associated definitional, conceptual, and methodological issues and challenges. Selected research literature on rural–urban differences in mental health and social deviancy is reviewed. There is little consensus on the causal relationship between urbanization, mental health, and social deviancy, although numerous environmental and social pathogenic processes have been posited and investigated. Data indicate rural and urban milieus can have both pernicious and salutory consequences and that more research is needed to specify critical etiological factors and their relationship to subpopulation characteristics. Suggestions for improving future research efforts are offered, including the use of more complex theoretical models, measurement indices, and data analysis procedures. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Cell cycle regulation in irradiated and nonirradiated cells

Exposure of cells to ionizing radiation induces damage in the DNA. The adverse consequences of such exposures depend on the amount of the DNA damage induced as determined by the absorbed dose, as well as by its form as determined by the linear energy transfer. In addition to physical determinants, biological factors critically affect radiation response. Cells have the ability to sense DNA damage, and to activate repair pathways that efficiently remove such damage and restore the integrity of the DNA. Highly sophisticated mechanisms further enable cells to actively stall growth and division after sensing DNA damage. Such inhibitory processes, termed checkpoints, may optimize repair and minimize the adverse consequences of DNA damage. We review the fundamental principles underlying checkpoints as they have emerged from active research in the last few years and discuss briefly their relevance to the practice of medical and radiation oncology.