基于香豆素并半花菁染料的可视化检测氰化物试纸的制备及应用研究

通过Knoevenagel缩合反应合成了探针分子1,探针分子1的结构用1HNMR进行了表征.通过紫外-可见光谱及荧光光谱研究了探针分子1检测CN-的能力,结果显示,向探针1的二甲基亚砜(DMSO)-H2O(95∶5,V∶V)磷酸缓冲盐溶液体系(PBS,pH=7.4)中加入Na+、Ca2+、Mg2+、F-、Cl-、Br-...     

基于四苯乙烯结构的阳离子荧光探针的设计合成及其应用

我们以四苯乙烯为荧光团,通过McMurry反应、Duff反应和胺醛缩合设计合成一种阳离子的荧光探针,该荧光探针可以在水与二甲亚砜体积比为2︰5的混合溶液中对铝离子做到特异性识别。在不加入离子和加入其它阳离子的情况下,荧光探针的荧光强度很低,而加入铝离子后,荧光强度大幅增强。而且,在其它阳离子对荧光探针对铝离子的荧光响应影响不大。     

基于席夫碱结构的香豆素类荧光探针的合成及性能研究

以3-甲酰基-7-二乙胺基香豆素和2-氨基烟酸为原料,合成了一种席夫碱结构的香豆素类荧光探针,该合成方法简单,收率较高,产物易提纯。研究结果表明,当往探针中加入Cu2+时,探针的荧光强度急剧升高,而加入其他金属离子时,探针的荧光强度变化较小,Cu2+浓度在0~5.0×10-4mol/L范围内,探针的荧光强度随着Cu2+溶度的增大而增强。     

新型酰腙类化合物的合成及阴离子识别研究

设计合成了一种新型的阴离子探针,1-羟基-4-甲基-二苯甲酮对硝基苯酰腙。通过核磁共振谱、质谱和元素分析对其结构进行表征,利用UV-Vis光谱、荧光光谱及1HNMR研究了受体与阴离子如AcO-、H2PO4-、F-、Cl-、Br-和I-的相互作用。结果表明,在不借助任何其他昂贵仪器的情况下,该探针分子在干燥DMSO溶液中能够较好的比色识别F-、H2PO4-和AcO-离子,结合常数表明,该阴离子受体对AcO-具有较高的选择性和荧光响应。最后通过1HNMR滴定进一步研究了1-羟基-4-甲基-二苯甲酮对硝基苯酰腙与阴离子F-的相互作用的本质。     

基于萘酚席夫碱结构的荧光增强型铝离子探针

金属离子Al3+在生命系统中起着非常重要的作用并影响着人类的健康,荧光分子探针由于方法简单、选择性和灵敏度高、现场实时监测、检出限低等优点吸引了更多的研究关注.通过一步缩合反应制备了基于萘酚席夫碱结构的荧光分子探针,该分子探针在DMSO/H2 O溶液中对Al3+具有较好的选择性.加入Al3+后分子探针溶液的荧光强度明显...     

基于萘酰亚胺为发光团的Zn2+荧光探针的合成与研究

设计合成了一种基于萘酰亚胺为发光团的Zn2+荧光探针.相对于其他常见金属离子,该探针对Zn2+具有较好的选择性.探针对Zn2的识别机理为Zn2+的加入导致C=N异构化受阻,荧光增强.探针对Zn2+的线性检出范围为0.3 ～2.0μmol/L,检出限为0.15 μmol/L.     

一种氟离子比色探针的合成及识别研究

设计合成了一种新型的氟离子探针——蒽酮-吲哚化合物。通过核磁共振光谱、质谱、红外光谱和元素分析对其结构进行表征,利用比色及UV-Vis光谱研究了该探针对不同阴离子的识别性能。结果表明,裸眼条件下该探针在DMSO溶液中能够选择性比色识别F-,并采用1HNMR光谱滴定证实了该探针与F-的去质子化作用本质。     

RAFT方法合成的共聚物荧光探针及其氟离子检测性能

本文基于分子间质子转移和诱导分子内电荷转移(ICT)机理,合成了以萘酰亚胺为发光基团、苯甲酰为F-检测基团的荧光单体,并采用可逆加成-断裂链转移(RAFT)聚合方法将其与N-异丙基甲基丙烯酰胺(NIPAM)进行共聚,制备了一种可以用于F-检测的共聚物荧光探针poly(NIPAMm-co-Napn)(简称PNap334),并分别在二氯甲烷-二甲基亚砜(9/1,V/V)溶液和固体薄膜中考察了聚合物PNap334对F-的响应。研究发现,聚合物溶液和聚合物膜对F-均有很好的识别作用,聚合物溶液对F-的检测限为1.05μmol/L。     

罗丹明B衍生物荧光探针的合成及其对Fe3 的检测

以罗丹明B与苯胺为原料,经过缩合反应制得一种罗丹明B衍生物的荧光探针F-1[3',6'-二(二乙基氨基)-2-苯基螺[异吲哚-3,9'-氧杂蒽]-1-酮],其结构通过1HNMR、13CNMR、红外光谱和高分辨质谱(HRMS)进行确证。Fe~(3+)加入探针体系后,体系颜色由无色变为紫色,荧光显著增强,而不受其他金属离子(Na~+、K~+、Ca~(2+)、Mg~(2+)、Zn~(2+)、Hg~(2+)、Co~(2+)、Cd~(2+)、Ni~(2+)、Cu~(2+)、Mn~(2+)、Ag+、Pb~(2+)、Cr~(3+)、Fe~(2+))干扰。通过测定探针化合物F-1的离子选择性、离子竞争性、浓度梯度、Job’s曲线和pH对探针分子荧光强度的影响,发现在p H=5～7的环境中,Fe~(3+)浓度在2.0×10~(–6)～1.8×10~(–5) mol/L时,探针F-1对其检测呈较好的线性关系,其具备定性、定量检测生物机体或者环境中痕量Fe~(3+)的潜力。     

钙黄绿素-Fe~(3+)荧光光谱法测定F~-

钙黄绿素与Fe3+发生络合反应,形成钙黄绿素-Fe3+荧光猝体系灭,当加入不同浓度的F-后,F-与Fe3+亲合力更强,将Fe3+从钙黄绿素-Fe3+络合物中夺取,而使钙黄绿素游离出来,荧光得以恢复。在一定范围内,荧光的恢复和F-浓度具有良好的线性关系。     

The synthesis,photophysical properties and fluoride anion recognition of a novel branched organoboron compound

A novel two-branched organoboron compound, N,N-bis(7-dimesitylboryl-9,9-diethyl-9H-fluorene-2-yl)aniline, containing a phenylamino group as a π-electron donor, fluorene groups as π-bridges and dimesitylboryl groups as electron acceptors, was synthesized and its photophysical properties in various solvents as well as its fluoride anion recognition properties were investigated. The synthesised compound exhibited strong fluorescence in all solvents with the fluorescence changing from blue to orange on going from solvents of low polarity to those of high polarity. The compound was able to recognize fluoride anions in high sensitivity owing to strong interactions between boron atoms and fluoride anions.     

Preparation and Characterization of Fluorescence Probe from Assembly Hydroxyapatite Nanocomposite

A new nanocomposite fluorescence probe with thioglycolic acid (TA) functional layers embedded inside the hydroxyapatite nanoribbon spherulites has been synthesized. The fluorescence intensity of the novel probe is about 1.5–3.3-fold increase compared with the probe containing no TA. When used to detect cadmium ion, the most of original assembly nanoribbon spherulites structure in the novel probe is found to have been damaged to new flake structures. The mechanism of determining cadmium ion in alcohol solution has been studied. The present systematic study provides significant information on the effect of assembly nanostructure on the metal-enhanced fluorescence phenomenon.     

A highly selective ratiometric fluorescent sensor for Hg2+ based on 1,8‐naphthalimide

A sulfur probe based on 1,8‐naphthalimide was designed and synthesised, and its sensing behaviour towards a mercury ion was investigated by fluorescence spectroscopy. The probe showed higher selective recognition towards Hg²⁺ than towards other metal ions in methanol solution. Compared with 4‐amino‐substituted naphthalimide derivatives, the probe exhibited different fluorescent characteristics for sensing Hg²⁺. The novel, reaction‐based probe is recommended for selective recognition of Hg²⁺ with significant fluorescence change.     

一种基于氧杂蒽结构的“Turn-Off”型荧光探针研究及对磷酸酯类物质检测

设计了一种基于氧杂蒽结构的"Turn-Off"型荧光探针(P3),在生理pH条件下对磷酸根(Pi)较好的荧光淬灭性能,在与其它竞争性含氧阴离子(硫酸根、硝酸根、碳酸氢根)以及其它常见阴离子(氟离子、氯离子、溴离子等)对该识别的竞争性影响考察中,亦显示了较好的特异性。从荧光滴定法得到荧光探针(P3)与磷酸根(Pi)形成超分子复合物的摩尔比为1∶1,复合物稳定常数K为5.28*103。通过量子化学计算表明磷酸根与!共轭体系产生了较强的相互作用,并导致P3分子平面上翘,在一定程度上破坏了原先的共面型,磷酸根上氧部位的孤对电子与!共轭体系存在着轨道交叠,即p-!共轭作用。可将此探针应用于磷酸酯类物质的检测。     

ANION EXCHANGE EXTRACTION AND ENRICHMENT FROM AQUEOUS SOLUTIONS BY QUARTERNARY AMMONIUM REAGENTS

The problems of solvent extraction and ion-exchange-based quantitative enrichment of anions having high hydration energies in aqueous solutions using water-insoluble quaternary ammonium salts are discussed. A new approach to anion exchange extraction of such anions by water-soluble polymeric quarternary ammonium salts is suggested in conjunction with membrane filtration. The retention of oxo anions of arsenic(V)r phosphorus(V), chromium(VI), selenium(IV) and of the fluoride ion with the permethylated derivative of poly-(ethyleneimine) and the influence of different salts on the retention of the anions have been studied and the possibility of quantitative retention of these anions has been demonstrated. For example, the retention for arsenic(V) was found to be 92% and 89% for fluoride with 2% polymer and a filtration factor of seven. After extraction the oxo anions can be stripped off easily in the cell solution up to 99% by 0.1 M HCl or a 0.15 M solution of sodium salts.     

改性沸石除氟的动态实验研究

为将阴离子型改性沸石应用于实际,通过动态吸附实验,对用改性沸石除氟技术的可行性进行了研究。实验对影响除氟的pH、水力停留时间、溶液中可能共存的阴离子竞争影响、前水的氟浓度的几个主要的因素水平进行了实验分析。得出在原水pH为7.7、水力停留时间为80 min、氟离子浓度为5 mg/L时改性沸石除氟动态平衡吸附量最佳。溶液中的阴离子SO42-对除氟效果影响较大     

Anion exchangers from shale tar

A weakly basic anion exchanger with an exchange capacity of 6.50 mg-equiv/g was prepared based on the polycondensate of shale tar with hexamethylenetetramine. This anion exchanger exhibited high performance characteristics such as relative rate of ion exchange and high mechanical strength; it can be used as an industrial ion exchanger for the preliminary purification of strongly contaminated media in the same areas where the commercial anion exchanger AN-2F is used.     

一种新的氨基硫脲类阴离子受体的合成及其性质研究

合成了一种新的阴离子受体化合物PySN,通过1H NMR对其进行了表征。受体分子结合不同阴离子的紫外-可见光谱和荧光发射光谱变化表明:在非质子性溶剂中,PySN可选择性识别和传感氟离子、醋酸根及磷酸二氢根离子。     

蒸氨废水化学沉淀除氟结晶动力学模型

以质量扩散-表面反应两步结晶理论为基础,推导出氟化钙沉淀结晶动力学模型,以蒸氨废水为研究对象,氯化钙为沉淀剂,采用间歇结晶和在线粒度监测技术测定了氟化钙结晶动力学数据,采用非线性优化技术获得了氟化钙结晶动力学模型参数,并对该模型进行了实验验证,结果表明模型及模型参数效果良好,模型值与实验值平均相对误差为3.37%。氟化钙沉淀结晶过程属于表面反应控制过程,氟化钙存在明显的聚结现象。模型模拟结果表明:钙离子浓度一定时,氟离子初始浓度越高则初始阶段氟离子浓度下降越快,初始氟离子浓度过高或过低,最终均不利获得较低的氟离子浓度;适当提高操作温度可以促进氟离子的净化,但温度过高则不利。