The effects of familial risk, personality, and expectancies on alcohol use and abuse.

This study tested a structural model of the association between familial risk, personality risk, alcohol expectancies, and alcohol abuse in a sample of 224 young adult offspring of alcoholics and 209 offspring of nonalcoholics. The results provided support for 2 personality-risk pathways, a social deviance proneness and an excitement/pleasure seeking path, that accounted for a significant portion of the association between a familial alcoholism and alcohol abuse. The path from familial alcoholism to social deviance proneness lead directly to alcohol problems. The path from familial alcoholism to excitement/ pleasure seeking was associated with increased drinking, which, in turn, was associated with alcohol problems. Positive alcohol expectancies accounted for part of the association between excitement seeking and alcohol use. The results suggest 2 different biopsychosocial mechanisms that elevate risk for abuse in the offspring of alcoholics. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

ALDH2, ADH1B and alcohol expectancies: Integrating genetic and learning perspectives.

The present study evaluated associations of ALDH2 and ADH1B genotypes with alcohol expectancies and drinking behavior in a sample of Asian American young adults. In addition to assessing global alcohol expectancies, the authors developed a measure of physiological expectancies to evaluate an expectancy phenotype specific to the mechanism by which ALDH2 and ADH1B variations presumably influence drinking behavior. Compared with individuals with the ALDH2*1/*1 genotype, those with the ALDH2*2 allele reported greater negative alcohol expectancies, greater expectancies for physiological effects of alcohol and lower rates of alcohol use. ADH1B was not associated with alcohol expectancies or drinking behavior. Hierarchical models showed that demographic factors, ALDH2 genotype, and expectancy variables explained unique variance in drinking outcomes. Mediation tests showed significant indirect effects of ALDH2 on drinking frequency and peak lifetime consumption through expectancies. These results provide support for influences of genetic factors and alcohol sensitivity on alcohol-related learning and suggest the importance of developing biopsychosocial models of drinking behavior in Asian Americans. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Indications for surgery in patients with minimally symptomatic primary hyperparathyroidism

Although childhood anxiety appears to aggregate in families, transmission could be explained by both genetic and shared environmental factors. Twin studies can be used to disentangle genetic and environmental effects. In this study, a systematically ascertained sample of twins was used to investigate whether anxiety symptoms are heritable. Parent-rated anxiety symptoms could best be explained by an additive genetic model with heritability estimated at 59%. However, when self ratings were analysed (in the adolescent subsample), familial transmission could be accounted for by shared environmental factors only.     

Modeling of alcohol use mediates the effect of family history of alcoholism on adolescent alcohol expectancies.

The relative impact of biological family history of alcoholism and exposure to abusive parental drinking on alcohol effect expectancies of adolescent offspring were investigated in the present study. Exposure to familial models of alcohol abuse and biological family history were both predictive of positive alcohol effect expectancies of adolescent offspring. Degree of exposure to an alcohol-abusing family member mediated the relationship between biological family history of alcoholism and adolescent alcohol outcome expectancies. These results support prior findings of expectancy differences between youths with and without a family background of alcoholism and provide evidence supporting the significance of family modeling influences in the development of adolescents' alcohol expectancies. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Relationship between nicotine and alcohol expectancies and substance dependence.

The relation between nicotine and alcohol expectancies and lifetime nicotine and alcohol dependence was examined. Higher expectancies for nicotine and alcohol were found for nicotine and alcohol-dependent groups, respectively, compared with asymptomatic and nonusing groups. These data extend work showing a positive relation between level of smoking and expectancy by showing that, with level of use controlled statistically, enhanced expectancies are characteristic of persons meeting Diagnostic and Statistical Manual of Mental Disorders (3rd ed., rev.; American Psychiatric Association, 1987) criteria for nicotine dependence. A similar relation was found between alcohol expectancies and alcohol dependence. Implications for understanding the role of cognitive factors in drug dependence are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Alcohol outcome expectancies as socially shared and socialized beliefs.

Alcohol expectancies are important predictors of alcohol involvement in both adolescents and adults, yet little research has examined the social origins and transmission of these beliefs. This paper examined alcohol outcome expectancies collected in a cohort-sequential longitudinal study of 452 families with children followed over seven waves. Children completed interviews every 6 months, and parents completed interviews annually. Eighteen of 27 alcohol expectancies were highly consensual, being endorsed by significantly more than 67% of the mothers and fathers. These consensual expectancies were also highly stable over a 3-year period. Over the same period, children increased their adoption of both the positive and negative consensual alcohol expectancies. Unconditional latent growth modeling showed that piece-wise growth models with a transition at age 12 fit the data best. Both the positive and negative consensual expectancies were adopted at a faster rate between ages 8.5 and 11.5 than between ages 12 and 13.5. For negative expectancies, there was no further growth between ages 12 and 13.5. Taken together, these findings support the conceptualization of alcohol outcome expectancies as socially shared and transmitted beliefs. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Predicting the emergence and persistence of alcohol dependence in young adults: The role of expectancy and other risk factors.

The relationship of alcohol outcome expectancies and other risk factors: demographic, personality, and affectivity, to alcohol dependence status was examined over a 3.5-year interval in 1,007 young adults. Lifetime prevalence of alcohol dependence was 18.1% at baseline. Of persons classified as current alcohol dependent at baseline, 66.9% experienced remission at the 3.5-year follow-up. Of persons classified as remitted alcohol dependent at baseline, 11.3% were current alcohol dependent at the 3.5-year follow-up. At follow-up, 5% of persons with no history of alcohol dependence at baseline met criteria for current alcohol dependence. Male gender, higher extraversion, and lower positive affect scores predicted emergent current alcohol dependence at the 3.5-year interval. Persistent current alcohol dependence was predicted by the expectation of improved social and sexual experiences following alcohol use. The findings suggest that positive expectancies may be an important factor in persistence of alcohol dependence and that their modification may enhance treatment of alcohol dependence in young adults. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

A cross-cultural comparison of alcohol expectancies in Puerto Rico and the United States.

This study compared the alcohol expectancies of 211 (62 men, 149 women) native Puerto Rican and 167 (54 men, 113 women) U.S. college students. Respondents completed a back-translated alcohol expectancy questionnaire. Results were factor analyzed separately by ethnicity. Comparison of factor structures indicated similarities and differences in expectancy structures. Puerto Rican respondents showed a tendency to associate positive aspects of alcohol effects with an expectancy for increased sociability, whereas for U.S. respondents these dimensions appeared to be independent. Puerto Ricans also had expectations of concurrent positive and negative alcohol effects on sexual behavior. A strong relationship between alcohol expectancies and alcohol consumption patterns was observed in both samples. Positive expectancies were better predictors of drinking than negative expectancies. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Parental alcohol involvement and adolescent alcohol expectancies predict alcohol involvement in male adolescents.

Current models of adolescent drinking behavior hypothesize that alcohol expectancies mediate the effects of other proximal and distal risk factors. This longitudinal study tested the hypothesis that the effects of parental alcohol involvement on their children's drinking behavior in mid-adolescence are mediated by the children's alcohol expectancies in early adolescence. A sample of 148 initially 9–11 year old boys and their parents from a high-risk population and a contrast group of community families completed measures of drinking behavior and alcohol expectancies over a 6-year interval. We analyzed data from middle childhood (M age = 10.4 years), early adolescence (M age = 13.5 years), and mid-adolescence (M age = 16.5 years). The sample was restricted only to adolescents who had begun to drink by mid-adolescence. Results from zero-inflated Poisson regression analyses showed that 1) maternal drinking during their children's middle childhood predicted number of drinking days in middle adolescence; 2) negative and positive alcohol expectancies in early adolescence predicted odds of any intoxication in middle adolescence; and 3) paternal alcoholism during their children's middle childhood and adolescents' alcohol expectancies in early adolescence predicted frequency of intoxication in middle adolescence. Contrary to predictions, child alcohol expectancies did not mediate the effects of parental alcohol involvement in this high-risk sample. Different aspects of parental alcohol involvement, along with early adolescent alcohol expectancies, independently predicted adolescent drinking behavior in middle adolescence. Alternative pathways for the influence of maternal and paternal alcohol involvement and implications for expectancy models of adolescent drinking behavior were discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Analysis of item response and differential item functioning of alcohol expectancies in middle school youths.

Drinking behavior in preadolescence is a significant predictor of both short- and long-term negative consequences. This study examined the psychometric properties of 1 known risk factor for drinking in this age group, alcohol expectancies, within an item response theory framework. In a sample of middle school youths (N = 1,273), the authors tested differential item functioning (DIF) in positive and negative alcohol expectancies across grade, gender, and ethnicity. Multiple-indicator multiple-cause model analyses tested differences in alcohol use as a potential explanation for observed DIF across groups. Results showed that most expectancy items did not exhibit DIF. For items where DIF was indicated, differences in alcohol use did not explain differences in item parameters. Positive and negative expectancies also systematically differed in the location parameter. Latent variable scale scores of both positive and negative expectancies were associated with drinking behavior cross-sectionally, while only positive expectancies predicted drinking prospectively. Improving the measurement of alcohol expectancies can help researchers better assess this important risk factor for drinking in this population, particularly the identification of those with either very high positive or very low negative alcohol expectancies. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Elementary School Drinking: The Role of Temperament and Learning.

Drinking in elementary school, despite its low base rate, has been shown to predict alcohol use in middle school (Wilson, Battistich, Syme, & Boyce, 2002), which in turn predicts alcohol abuse or dependence in young adults (Guo, Collins, Hill, & Hawkins, 2000). The authors report 1 of the 1st examinations of the relationship between personality and psychosocial learning risk factors and drinking behavior among elementary school students. Fifth-grade students completed measures of disinhibition, positive and negative alcohol expectancies, and drinking. MIMIC modeling, tests of mediation, and tests of moderation were completed to test these relations. It was found that disinhibition and positive alcohol expectancies were each related to drinking in 5th graders. Disinhibition moderated the relation between positive alcohol expectancies and drinking in some cases. Mediation was not supported. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Searching for an environmental effect of parental alcoholism on offspring alcohol use disorder: A genetically informed study of children of alcoholics.

The children-of-twins design was used to isolate a potentially causal environmental impact of having an alcoholic parent on offspring alcohol use disorder, by an examination of whether the children of alcoholics were at a higher risk for alcohol use disorders than were the children of nonalcoholic parents, even after correlated familial factors were controlled. Participants were 1,224 male and female twins from 836 twin pairs selected from the Australian Twin Registry, 2,334 of the twins' 18-39-year-old offspring, and 983 spouses of the twins. Lifetime histories of Diagnostic and Statistical Manual of Mental Disorders (4th ed.) alcohol use disorders were obtained by structured, psychiatric, telephone interviews conducted individually with each of the family members. Comparisons of the offspring of twins who were discordant for alcoholism indicated that there was no longer a statistically significant difference between the children of alcoholics and the children of nonalcoholics after genetic and family environmental factors correlated with having an alcoholic parent were controlled. The results of this study suggest that the direct causal effect of being exposed to an alcoholic parent on offspring alcohol use disorder is modest at best. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The P300 as an electrophysiological probe of alcohol expectancy.

Language-based measures indicate that alcohol expectancies influence alcohol consumption. To relate these measures to brain actions that precede verbal output, the P300 component of the Event-related potentials (ERPs) was used to detect violations of individually held alcohol expectancies. As predicted, P300 amplitude elicited by negative alcohol expectancy stimuli was positively correlated with endorsement of positive/arousing alcohol expectancies on the language-based measures, such that the higher an individual's positive/arousing expectancies, the larger was the P300 elicited by negative alcohol expectancy stimuli. These results demonstrated concordance between language-based measures of alcohol expectancies and electrophysiological probes of expectancy. While it remains unknown whether these expectancy processes are integral to decision pathways that influence consumption, these findings suggest that such processing can occur very quickly outside of conscious deliberation. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Effects of a drinking event on behavioral skills and condom attitudes in men: Implications for HIV risk from a controlled experiment.

This study experimentally tested the effects of a drinking event on HIV-related behavioral skills and condom attitudes. Sixty unmarried, heterosexual men were assigned to 1 of 3 conditions (sober, placebo, or alcohol). Participants who consumed alcohol demonstrated lower skill to negotiate for condom use relative to sober controls. More negative condom attitudes were expressed by participants with stronger sex-related alcohol expectancies, especially when these expectancies were triggered by subjective intoxication. Hierarchical regression analyses revealed that the experimental factors accounted for variance in behavioral skills and condom attitudes beyond that explained by known predictors of sexual risk. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Integrating biological and behavioral factors in alcohol use risk: The role of ALDH2 status and alcohol expectancies in a sample of Asian Americans.

Prior studies have shown that the ALDH2*2 genetic variant, most common in individuals of Asian descent, is related to heightened sensitivity to alcohol and can serve as a protective factor against alcohol problems. This study explored the effect of this factor on alcohol expectancies. It was hypothesized that (a) individuals with ALDH2*2 alleles would have lower positive expectancies and higher negative expectancies, (b) expectancies would mediate the ALDH2-drinking relation, and (c) ALDH2 status would moderate the expectancy-drinking relation. Data were collected from 171 Asian American university students. Positive expectancy and ALDH2 status were correlated with alcohol use. Mediation and moderation hypotheses were supported only in the female sample. Results were not significant for negative expectancies. These results indicate that ALDH2 status may protect against drinking by lowering positive expectancies and reducing the expectancy-drinking relationship. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Adolescent alcohol expectancies in relation to personal and parental drinking patterns.

Increased expectations of positive effects of alcohol have been associated with severity of drinking across a variety of abusing and nonabusing adult populations. Although alcohol expectancies have been examined among high school adolescents, no study has examined expectancies of identified adolescent abusers in treatment. This study investigated whether adolescent alcohol abusers in treatment expect significantly more reinforcement from alcohol than do nonabusing peers and whether expectancies vary as a function of exposure to parental alcohol abuse. The adolescent version of the Alcohol Expectancy Questionnaire (Christiansen, Goldman, & Inn, 1982) was completed by 116 abusing and nonabusing adolescents. Results indicate that adolescent alcohol abusers expect significantly more reinforcement from alcohol than do demographically comparable nonabusing peers. Adolescents with an alcohol-abusing parent reported expecting more cognitive and motor enhancement from drinking than did adolescents without a family history of abuse. Thus, both personal alcohol use and parental alcohol use are related to adolescent alcohol expectancies. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Alcohol expectancies as a mediator of the relationship between injury and readiness to change drinking behavior.

There is a well-established relationship between alcohol expectancies and drinking behavior. The purpose of the present study was to extend the literature by examining the role of alcohol expectancies in determining readiness to change drinking behavior among injured emergency department patients who screened positive for hazardous drinking. Negative expectancies were found to partially mediate the relationships of alcohol-related injuries and injury aversiveness to readiness to change drinking behavior. Results suggest that negative alcohol expectancies are a potential means of increasing patients' readiness to change drinking behavior. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Risk factors for elementary school drinking: Pubertal status, personality, and alcohol expectancies concurrently predict fifth grade alcohol consumption.

Little is known about the correlates and potential causes of very early drinking. The authors proposed this risk theory: (a) pubertal onset is associated with increased levels of positive urgency (the tendency to act rashly when experiencing intensely positive mood), negative urgency (the tendency to act rashly when distressed), and sensation seeking; (b) those traits predict increased endorsement of high-risk alcohol expectancies; (c) the expectancies predict drinker status among fifth graders; and (d) the apparent influence of positive urgency, negative urgency, and sensation seeking on drinker status is mediated by alcohol expectancies. The authors conducted a concurrent test of whether the relationships among these variables were consistent with the theory in a sample of 1,843 fifth grade students. In a well-fitting structural model, their hypotheses were supported. Drinker status among fifth graders is not just a function of context and factors external to children: it is predictable from a combination of pubertal status, personality characteristics, and learned alcohol expectancies. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Perceived exposure to peer and adult drinking as predictors of growth in positive alcohol expectancies during adolescence.

This study investigated the effects of change in exposure to peer and adult drinking on changes in positive alcohol expectancies during adolescence. Covariance and mean structure analysis were used to model change in the predictors and in alcohol expectancies in a sample of southern California schoolchildren followed from Grades 5 to 10 (N?=?3,580). The sample was gender balanced and was predominantly White (51 %) and Hispanic (28%). Exposure to peer drinking and rate of change in exposure to peer and adult drinking were found to predict the rate of change in alcohol expectancies. These effects were particularly strong between Grades 5 and 7, suggesting the need for early intervention aimed to prevent the increase in positive alcohol expectancies. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Alcohol expectancy priming and drinking behavior: The role of compatibility between prime and expectancy content.

According to information-processing models of alcohol use, alcohol expectancies constitute representations in long-term memory that may be activated in the presence of drinking-related cues, thereby influencing alcohol consumption. A fundamental implication of this approach is that primed expectancies should affect drinking only for those individuals who possess the specific expectancies primed. To test this notion, in the present study, participants were initially assessed on 3 distinct domains of positive alcohol expectancies. Approximately 1 week later, they completed an ad libitum drinking study during which only a single expectancy domain (sociability) was primed in the experimental condition. Consistent with predictions, following exposure to sociability primes but not control primes, individuals with stronger expectancies that alcohol would enhance sociability uniquely showed increased placebo consumption of nonalcoholic beer. These results, which demonstrate the moderating role of compatibility between the specific content of primes and that of underlying expectancies, offer new, direct support for memory network-based models of drinking behavior. (PsycINFO Database Record (c) 2010 APA, all rights reserved)