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1.
E. N. Frankel W. E. Neff W. K. Rohwedder B. P. S. Khambay R. F. Garwood B. C. L. Weedon 《Lipids》1977,12(12):1055-1061
The gas chromatography-mass spectrometry (GC-MS) method developed in the preceding papers was extended to the analysis of
autoxidation products of methyl linolenate. Four isomeric hydroxy allylic trienes with a conjugated diene system were identified
after reduction of the linolenate hydroperoxides. All eight geometrictrans,cis- andtrans, trans-conjugated diene isomers of these hydroxy allylic compounds were identified and partially separated by GC of the trimethylsilyl
(TMS) ether derivatives. The proportion found of 9- and 16-hydroperoxides was significantly higher (75–81%) than the 12- and
13-hydroperoxides (18–25%). The tendency of the 12- and 13-hydroperoxides to form cyclic peroxides, cyclic peroxidehydroperoxides,
and prostaglandin-like endoperoxides was supported by indirect evidence for the presence of 9,10,12- and 13,15,16-trihydroxyoctadecanoate
in hydrogenated derivatives of the highly oxygenated products. The quantitative GC-MS method was used to determine the relative
contribution of linolenate, linoleate, and oleate in mixtures to the formation of hydroperoxides.
Presented at the AOCS Meeting, New York, May 1977. 相似文献
2.
Summary 1. Kinetic studies showed that concurrent oxidation of preformed hydroperoxides may be expected to take place at all stages
of the autoxidation of methyl linoleate. The rate of oxidation relative to the rate of autoxidation of unoxidized ester is
determined chiefly by the extent of the accumulation of hydroperoxides.
2. Infrared spectral analysis of hydroperoxides oxidized to various degrees indicated thattrans, trans diene conjugation and isolatedtrans double bonds produced in the autoxidation of methyl linoleate are related to the concurrent oxidation of the accumulated
hydroperoxides.
3. The low absorptivity observed for diene conjugation, compared to that which may be expected for the exclusive production
ofcis, trans diene conjugated hydroperoxide isomers during the autoxidation of methyl linoleate is attributed to the concurrent oxidation
of accumulated hydroperoxides.
4. The effect of antioxidants in giving a well-defined induction period in the oxidation of hydroperoxides isolated from autoxidized
methyl linoleate indicated that the oxidation proceeds by a chain reaction.
5. The primary reaction products of the oxidation of hydroperoxides isolated from autoxidized methyl linoleate were found
to be polymers formed in a sequence of reaction involving the diene conjugation.
6. Studies on the autoxidation of methylcis-9,trans-11-linoleate showed thatcis, trans isomerization of the conjugated diene took place with the concurrent production of isolatedtrans double bonds and loss of diene conjugation.
Hormel Institute publication no. 138. Presented before the American Oil Chemists’ Society, Philadelphia, Pa., Oct. 10–12,
1955.
This work was supported by a grant from the Hormel Foundation. 相似文献
3.
The antioxidant effects of ion exchange resins and ethyleneimine polymer on the autoxidation products of methyl linoleate
in a heterogeneous reaction system are discussed. Results from analyses of the various autoxidation products from linoleate
samples with and without the antioxidants showed that the addi-tion of the antioxidants did not change the original autoxidation
mechanism of methyl linoleate. How-ever, the antioxidants did retard the autoxidation in response to their antioxidant activity
and, compared with a linoleate control, changed the yields of some autoxidized products such as an increased amount of conjugated
diene hydroperoxides in linoleate samples with added ion exchange resins. 相似文献
4.
To clarify the sources of undesirable flavors, pure hydroperoxides from autoxidized and photosensitized oxidized fatty esters
were thermally decomposed in the injector port of a gas chromatograph-mass spectrometer system. Major volatile products were
identified from the hydroperoxides of methyl oleate, linoleate and linolenate. Although the hydroperoxides from autoxidized
esters are isomerically different in position and concentration than those from photosensitized oxidized esters, the same
major volatile products were formed but in different relative amounts. Distinguishing volatiles were, however, produced from
each type of hydroperoxide. The 9- and 10-hydroperoxides of photosensitized oxidized methyl oleate were thermally isomerized
in the injector port into a mixture of 8-, 9-, 10- and 11-hydroperoxides similar to that of autoxidized methyl oleate. Under
the same conditions, the hydroperoxides from autoxidized linoleate and linolenate did not undergo significant interconversion
with those from the corresponding photosensitized oxidized esters. The compositions of the major volatile decomposition products
are explained by the classical scheme involving carboncarbon scission on either side of alkoxy radical intermediates. Secondary
reactions of hydroperoxides are also postulated, and the hydroperoxy cyclic peroxides from methyl linoleate (photosensitized
oxidized) and methyl linolenate (both autoxidized and photosensitized oxidized) are suggested as important precursors of volatiles. 相似文献
5.
Analysis of autoxidized fats by gas chromatography-mass spectrometry: I. Methyl oleate 总被引:1,自引:0,他引:1
E. N. Frankel W. E. Neff W. K. Rohwedder B. P. S. Khambay R. F. Garwood B. C. L. Weedon 《Lipids》1977,12(11):901-907
A structural investigation of autoxidation products of methyl oleate was carried out by gas chromatography-mass spectrometry
(GC-MS) of trimethylsilyl (TMS) ether derivatives. GC-MS using computer plots of selected masses afforded structural assignments
of GC peaks due to incompletely resolved mixtures. This method provided evidence of epoxy and keto esters which are not completely
separated from the main components consisting of the TMS derivatives of the allylic hydroxy esters. Use of an MS-computer
system also showed that the hydroxyoctadecanoate TMS ethers were partially separated by GC. The use of synthetic hydroxyoctadecanoates
for the first time enabled us to demonstrate the quantitative reliability of a GC-MS computer summation approach to analyze
the isomeric composition of oleate hydroperoxides (as the saturated TMS ether derivatives). Consistently higher concentrations
were found of the 8- and 11-hydroperoxides than of the 9- and 10-hydroperoxides. Minor products of autoxidation identified
by GC-MS include allylic enones, isomeric epoxyoctadecanoates, dihydroxyctadecenoates, and dihydroxyoctadecanoates.
Presented at the AOCS Meeting, Chicago, September 1976. 相似文献
6.
The hydroperoxides and secondary products formed from trilinoleoylglycerol autoxidized at 40°C were isolated and characterized
to clarify their contribution to oxidative deterioration of vegetable oils. The products were purified by high performance
liquid chromatography (HPLC) and identified, as intact triacylglycerols, by ultraviolet, infrared,1H NMR and13C NMR analyses, and after derivatization by lipolysis, gas chromatography, and gas chromatography-mass spectrometry. The main,
primary products included mono-,bis- and tris-9-hydroperoxy-trans-10,cit-12-; 9-hydroperoxy-trans-10,trans-12; 13-hydroperoxy-cis-9,trans-11; and 13-hydroperoxy-trans-9,trans-11-linolenoyl glycerols. The structures of the minor secondary products analyzed after derivatization were consistent with
known oxidative degradation products of linoleate hydroperoxides. HPLC analyses showed that thebis- and tris-hydroperoxides were formed from the mono-hydroperoxides during autoxidation at peroxide values above 18 and 28
meq/kg. Studies on the further oxidation of the mono-hydroperoxides support a mechanism for the consucutive formation ofbis- and tris-hydroperoxides from the monohydroperoxides. HPLC analyses showed that no preferential oxidation occurred between
the 1(3)- and 2-triglyceride positions. Hydroperoxides of linoleate triacylglycerols may be important precursors of volatile
compounds contributing to off-flavors of vegetable oils.
Presented at the 79th Annual American Oil Chemists' Society Meeting, Phoenix, Arizona, May 8–12, 1988. 相似文献
7.
Previous studies of secondary oxidation products by high-pressure liquid chromatography (HPLC) of autoxidized methyl oleate,
linoleate and linolenate and photosensitized-oxidized linoleate are extended to photosensitized-oxidized linolenate. Photosensitized-oxidized
linolenate was fractionated by silicic acid chromatography with diethyl ether/hexane mixtures. Selected silicic acid chromatographic
fractions were separated by polar phase HPLC and characterized by thin layer and gas liquid chromatography and by ultraviolet,
infrared, nuclear magnetic resonance and mass spectrometry. Secondary products from the photosensitized oxidation mixtures
(containing 8.2 to 29.0% monohydroperoxides) included keto- and epoxy-dienes (0.4–1.6%), hydroperoxy epidioxides (0.8–4.9%),
hydroperoxy bicyclic monoenes (0.1–0.3%), dihydroperoxides (1.0–5.6%), and hydroperoxy bisepidioxides (0.7–1.6%). Some of
these secondary products are new and unique to photosensitized oxidation. Cyclization of the 10-, 12-, 13- and 15-hydroperoxides
of linolenate would account for their lower relative concentration than that found for the 9- and 16-hydroperoxides. Dihydroperoxides
may be derived from monohydroperoxides by singlet oxygenation or free radical oxidation. The hydroperoxy bis-epidioxides may
be formed by further serial cyclization of the hydroperoxy epidioxides from 10- and 15-monohydroperoxides. Dihydroperoxides,
hydroperoxy epidioxides and hydroperoxy bis-epidioxides are suggested as important flavor precursors in oxidized fats.
The mention of firm names or trade products does not imply that they are endorsed by the US Department of Agriculture over
other firms or similar products not mentioned. 相似文献
8.
The formation of dimers was demonstrated in methyl linoleate hydroperoxides decomposed by bubbling with dry air at 30 C. The
dimer fraction isolated by gel permeation chromatography was further fractionated by successive silicic acid column and high
performance liquid chromatography. Major components were analyzed after derivatizations by gas chromatography-mass spectrometry
with several ionization methods, i.e., electron impact, chemical ionization and field desorption.
After aeration for 90 min, 1.4% of the hydroperoxides were decomposed. However, almost all of the secondary products were
dimers, while polar monomeric and low molecular products were negligible. After aeration for 390 min, both polar monomeric
(5.0%) and low molecular (0.8%) compounds formed, but dimers and polymers (18.1%) were still the major products. These results
show the importance of polymerization in the aerobic breakdown of hydroperoxides.
The dimers isolated from hydroperoxides aerated 90 min could be separated into two fractions according to their polarities.
The dimers identified usually were composed of octadecadienoate and oxygenated octadecenoate moieties crosslinked through
either ether or peroxy linkages across C-9 or C-13 positions. The oxygen-containing functional groups found in the dimers
include hydroperoxy, hydroxy and oxo groups. The polar dimers had two of these groups per molecule, while the less polar dimers
had one. The main constituents of dimers were linked through peroxy bridges and found to be similar to the dimers previously
identified in autoxidized methyl linoleate. These dimers are suggested as important intermediates in linoleate oxidation and
as precursors of flavor deterioration. 相似文献
9.
A previous study of autoxidation products by high pressure liquid chromatography (HPLC) of methyl oleate and linoleate was
extended to methyl linolenate. Autoxidized methyl linolenate was fractionated by HPLC either after reduction to allylic alcohols
on a reverse phase system, or directly on a micro silica column. Isolated oxidation products were characterized by thin layer
and gas liquid chromatography and by ultraviolet, infrared, nuclear magnetic resonance and mass spectrometry. Secondary products
from the autoxidation mixtures (containing 3.5–8.5% monohydroperoxides) included epoxy unsaturated compounds (0.2–0.3%), hydroxy
or hydroperoxy-cyclic peroxides (3.8–7.7%), epoxy-hydroxy dienes (<0.1%), dihydroxy or dihydroperoxides with conjugated diene-triene
and conjugated triene systems (0.9–2.9%). Cyclization of the 12- and 13-hydroperoxides of linolenate would account for their
lower relative concentration than the 9- and 16-hydroperoxides. Dihydroperoxides may be derived from the 9- and 16-linolenate
hydroperoxides. Cyclic peroxides and dihydroperoxides are suggested as important flavor precursors in oxidized fats. 相似文献
10.
E. N. Frankel C. D. Evans D. G. Mcconnell E. P. Jones 《Journal of the American Oil Chemists' Society》1961,38(3):134-137
A liquid partition chromatographic method was developed to isolated and determine hydroperoxides in autoxidized fatty acids
or their methyl esters. By the use of benzene containing 2 to 4% methanol as the mobile solvent, the hydroperoxides were separated
from unoxidized fatty acids or methyl esters and from secondary and polymeric decomposition products. In the analyses of oxidized
fatty acids, diethyl ether was necessary to elute the secondary decomposition products.
Saponification of autoxidized fatty esters destroyed the peroxides as determined iodometrically, but the resulting acids contained
a fraction which was eluted in the same position as hydroperoxide acids. Evidence showed that this fraction is a monomeric
hydroxy fatty acid containing conjugated cis-traux and trans-trans unsaturation.
Fatty ester hydroperoxides were isolated chromatographically in yields and purity comparable to those reported in the literature
by countercurrent distribution. The concentrations of methyl linoleate hydroperoxide determined chromatographically were smaller
than indicated by the peroxide value and diene conjugation of the autoxidized methyl linoleate.
This is a laboratory of the Northern Utilization Research and Development Division, Agricultural Research Service, U.S. Department
of Agriculture. 相似文献
11.
Oleic, linoleic and linolenic acids were autoxidized more rapidly than their corresponding methyl esters. Addition of stearic
acid accelerated the rate of autoxidation of methyl linoleate and the decomposition of methyl linoleate hydroperoxides. Therefore,
the higher oxidative rate of FFA’s than their methyl esters could be due to the catalytic effect of the carboxyl groups on
the formation of free radicals by the decomposition of hydroperoxides. Addition of stearic acid also accelerated the oxidative
rate of soybean oil. This result suggests that particular attention should be paid to the FFA content that affects the oxidative
stability of oils. 相似文献
12.
To study the toxicity of low molecular weight (LMW) compounds formed during the autoxidation of oils,14C-labeled primary monomeric compounds (methyl linoleate hydroperoxides) and secondary oxidation products, i.e., polymer and
LMW compounds prepared from autoxidized methyl [U-14C]linoleate hydroperoxides (MLHPO) were orally administered to rats, and their radioactive distributions in tissues and organs
were compared. The polymeric fraction consisted mainly of dimers of MLHPO. For the LMW fraction, 4-hydroxy-2-nonenal, 8-hydroxy
methyl octanoate and 10-formyl methyl-9-decenoate were identified as major constituents by gas chromatography-mass spectrometry
(GC-MS) after chemical reduction and derivatization. When LMW compounds were administered to rats,14CO2 expiration and the excreted radioactivity in urine in 12 hr were significantly higher than those from polymer or MLHPO administration.
Maximum14CO2 expiration appeared 2–4 hr after the dose of LMW compounds. Radioactivity of the upper part of small intestines six hr after
the dose of LMW compounds was higher than the values from administered polymer or MLHPO. The remaining radioactivity in the
digestive contents and feces 12 hr after administration of LMW compounds was much lower than the values observed from administered
polymer or MLHPO. Among internal organs, the liver contained the highest concentration of radioactivities from polymer, MLHPO
and LMW fractions, and an especially higher level of radioactivity was found in liver six hr after the administration of LMW
compounds. Six hours after the dose of LMW compounds, a relatively higher level of radioactivity also was detected in kidney,
brain, heart and lung. These results show that the LMW compounds from MLHPO autoxidation are more easily absorbed in rat tissues
than polymer and MLHPO. 相似文献
13.
Taina I. Hmlinen Susanna Sundberg Marjukka Mkinen Seppo Kaltia Tapio Hase Anu Hopia 《European Journal of Lipid Science and Technology》2001,103(9):588-593
The aim of this study was to investigate whether hydroperoxides are formed in the autoxidation of conjugated linoleic acid (CLA) methyl ester both in the presence and absence of α‐tocopherol. The existence of hydroperoxide protons was confirmed by D2O exchange and by chemoselective reduction of the hydroperoxide groups into hydroxyl groups using NaBH4. These experiments were followed by nuclear magnetic resonance (NMR) spectroscopy. The 13C and 1HNMR spectra of a mixture of 9‐hydroper‐oxy‐10‐trans,12‐cis‐octadecadienoic acid methyl ester (9‐OOH) and 13‐hydroperoxy‐9‐cis, 11‐trans‐octadecadienoic acid methyl ester (13‐OOH), which are formed during the autoxidation of methyl linoleate, were studied in detail to allow the comparison between the two linoleate hydroperoxides and the CLA methyl ester hydroperoxides. The 13CNMR spectra of samples enriched with one of the two linoleate hydroperoxide isomers were assigned using 2D NMR techniques, namely Correlated Spectroscopy (COSY), gradient Heteronuclear Multiple Bond Correlation (gHMBC), and gradient Heteronuclear Single Quantum Correlation (gHSQC). The 13C and 1H NMR experiments performed in this study show that hydroperoxides are formed during the autoxidation of CLA methyl ester both in the presence and absence of α‐tocopherol and that the major isomers of CLA methyl ester hydroperoxides have a conjugated monohydroperoxydiene structure similar to that in linoleate hydroperoxides. 相似文献
14.
Mechanism of lipoxidase reaction. I. Specificity of hydroperoxidation of linoleic acid 总被引:3,自引:0,他引:3
Linoleate hydroperoxides from autoxidation of methyl linoleate and from lipoxidase oxidation of linoleic acid are compared.
Data indicate an equal amount of methyl 9- and 13-hydroperoxyoctadecadienoate produced by autoxidation of methyl linoleate,
and the exclusive formation of 13-hydroperoxyoctadeca-9,11-dienoic acid from the incubation of lipoxidase with linoleic acid.
As a result of these findings, a specific mechanism for the reaction of lipoxidase with linoleic acid is postulated.
Presented at the AOCS Meeting, Philadelphia, October 1966.
This work was conducted under a Postdoctoral Resident Research Associateship established at the Northern Laboratory by ARS,
USDA, in association with the National Academy of Sciences-National Research Council.
No. Utiliz. Res. Dev. Div., ARS, USDA. 相似文献
15.
T. Chiba K. Fujimoto T. Kaneda S. Kubota Y. Ikegami 《Journal of the American Oil Chemists' Society》1981,58(5):587-590
The structure of free radicals generated in the autoxidation of methyl linoleate (ML) was studied by the spin trapping technique
using deuterated nitrosodurene, (CD3)4C6HNO, as the spin trap. The secondary alkyl radicals were trapped after irradiation of ML with UV light. The formation rate
of secondary alkyl radicals increased upon shortening the wavelength of irradiation light and was closely correlated with
the peroxide value of autoxidized ML when a UV light longer than 250 nm was employed. When hydroperoxides separated from autoxidized
ML were added to ML, the relationship between the formation rate of secondary alkyl radicals and the amounts of added hydroperoxides
was nearly linear. These results suggest that secondary alkyl radicals are generated by proton abstraction of the active radicals,
such as RO and HO, which are produced by the photolysis of hydroperoxides with UV light. The spin trapping technique can be
applied to the study of lipid oxidation and/or photolysis of autoxidized lipid. 相似文献
16.
Henry W. -S. Chan 《Journal of the American Oil Chemists' Society》1977,54(3):100-104
The photo-sensitized oxidation of methyl linolenate and methyl oleate was studied using erythrosine and riboflavin as sensitizers.
The complex mixtures of hydroperoxides obtained were analyzed for the proportion of conjugated products and, after reduction
to the corresponding mixtures of hydroxystearates, for the distribution of positional isomers. By comparing the mixtures with
that obtained from autoxidation, it was shown that the riboflavin reaction involved the “Type 1” mechanism of photosensitized
oxidation which proceded via the formation of diene-radicals and yielded the same positional isomers of hydroperoxides as
autoxidation. Thus, mixtures of the 8, 9, 10, and 11 positional isomers of allylic hydroperoxides were formed from oleate
and the 9, 12, 13, and 16 isomers of conjugated diene-hydroperoxides from linolenate oxidation. The erythrosine reaction,
on the other hand, proceded via the “Type 2”. mechanism which involved singlet oxygen as the oxygenating species. The mixtures
of isomers resulting from oxidation involving singlet oxygen were different from those obtained by autoxidation. Oleate oxidation
gave rise to a mixture of only the 9 and 10 positional isomers while the mixture obtained from oxidation of methyl linolenate
contained non-conjugated hydroperoxide isomers (with the hydroperoxide group at positions 10 and 15) as well as the conjugated—9,
12, 13, and 16—isomers. 相似文献
17.
A. G. Gopala Krishna J. V. Prabhakar 《Journal of the American Oil Chemists' Society》1992,69(2):178-183
The role of water activity on the formation of peroxides and carbonyl compounds during lipid oxidation is important to know
because there could be either beneficial or detrimental effects of water activity on lipid oxidation in stored foods. Therefore,
methyl linoleate was chosen as a model lipid and was autoxidized to 1% at water activity ranging from 0.02 to 0.79 at 37°C.
Oxygen uptake was monitored manometrically. The peroxide and carbonyl contents were determined upon termination of the autoxidation
studies. Methyl linoleate autoxidation was characterized by three phases: i) an initial induction period of no oxygen absorption;
ii) a slow rate of oxygen absorption, up to 0.15% oxidation; and iii) a relatively faster rate of oxygen absorption beyond
0.15% up to 1% oxidation. Water activity had considerable influence during the first phase. There was no induction period
at or below water activity 0.22. The induction period begins at water activity 0.32 and could be extended to a limit with
increase in water activity. Once the induction period was passed water activity had no influence on the rate of oxidation.
However, during the second and third phases water activity becomes important in the stabilization of peroxides/hydroperoxides
and decides the course of secondary reactions that follow peroxide decomposition. Higher water activity values, particularly
water activity 0.67, tended to stabilize peroxides. Water activity had considerable influence on the formation of secondary
products of autoxidation as evidenced by the variation in the type and quantity of carbonyl compounds at different water activity
values. 相似文献
18.
Methyl linoleate, emulsified in borate buffer with sodium lauryl sulfate, was used to study the pro- or antioxidant effect
of 0-phosphocholine, 0-phosphoethanolamine, 0-phosphoserine, as well as the corresponding nonphosphoryl compounds. Oxygen
uptake was calculated from rate data obtained at 37 C with an oxygen electrode. The results were similar for the corresponding
phosphoryl and nonphosphoryl bases. 0-Phosphocholine and choline had little effect at either pH 7.9 or 10.2. 0-Phosphoethanolamine
and ethanolamine significantly increased oxygen uptake at pH 7.9, but significantly decreased uptake at pH 10.2. 0-Phosphoserine
and serine decreased oxygen uptake at both pH values. The catalytic activities of the bases investigated may be attributed
to their functional groups. The phosphoryl and β-hydroxy groups exhibited no catalytic activity in the autoxidation of methyl
linoleate emulsions at either pH 7.9 or 10.2. The α-carboxyl amino group of 0-phosphoserine and serine decelerated autoxidation
at both pH values. The amino group H3N+ of the primary amine accelerated autoxidation, but the H2N: group and the reverse effect. Since the quaternary amino group (CH3)3N+ did not affect autoxidation at either pH 7.9 or 10.2, we concluded that the presence of the N−H bond may be necessary for
the prooxidant activity of an amine, and that the presence of a pair of free electrons on the nitrogen of an amine is necessary
for its antioxidant activity. Kinetically, the autoxidation of methyl linoleate emulsion without added base was in agreement
with Farmer’s proposed mechanism involving a bimolecular dissociation of hydroperoxides. However, methyl linoleate emulsion
at pH 7.9 and 37 C in the presence of ethanolamine or 0-phosphoethanolamine was autoxidized by a mechanism involving a combined
mono- and bimolecular dissociation of hydroperoxides.
Submitted as partial requirement for a Ph.D. degree in Agricultural Chemistry. Presented in part at the AOCS Meeting, San
Francisco, April 1969. 相似文献
19.
High-molecular weight compounds previously were found to be important secondary products from autoxidation of polyunsaturated
fatty esters. The contribution of dimers to oxidative deterioration was investigated by analyzing their volatile thermal decomposition
products by capillary gas chromatography-mass spectrometry. Dimers were isolated by gel permeation chromatography from autoxidized
linolenate and from the corresponding monohydroperoxides, cyclic peroxides and dihydroperoxides. Major volatile decomposition
products identified from these oxidative dimers were similar to those formed from the corresponding monomeric hydroperoxides.
However, dimers from linolenate hydroperoxides produced more propanal and methyl 9-oxononanoate than the corresponding monomers
but less methyl octanoate and much less or no 2,4-heptadienal and 2,4,7-decatrienal. Significant differences in minor volatile
products also were observed between dimeric and monomeric products of methyl linolenate oxidation compounds. Mechanisms are
suggested for the formation of volatile decomposition products from different dimeric structures. These dimers are believed
to be important sources of volatile compounds contributing to flavor and oxidative deterioration of fats. 相似文献
20.
The effects of oxygen pressure, substrate concentration and solvent on the rate and products of oxidation of methyl linoleate
were studied at 50 C with azobisisobutyronitrile as a radical initiator. The absolute and quantitative numbers for oxygen
uptake, substrate disappearance, and formation of conjugated diene and hydroperoxides were measured. Under the present conditions,
4 conjugated diene hydroperoxides, 13-hydroperoxy-9-cis, 11-trans-(2a), 13-hydroperoxy-9-trans, 11-trans-(3a), 9-hydroperoxy-10-trans, 12-cis-(4a), and 9-hydroperoxy-10-trans, 12-trans-(5a) octadecadienoic acid methyl esters, were formed almost quantitatively. The rate of oxidation decreased with decreasing oxygen
pressure. However, the ratio ofcis,trans totrans,trans hydroperoxides, (2a+4a)/(3a+5a), was independent of oxygen pressure, and this ratio increased with increasing methyl linoleate concentration, as found recently
by Porter. Further, the rate of oxidation and the ratio ofcis,trans/trans,trans hydroperoxides were dependent on solvent and increased with an increase in dielectric constant of solvent. A mechanism of
methyl linoleate oxidation consistent with these results is discussed.
Presented at the 15th Symposium on Oxidation Reactions, Nagoya, October 1981. 相似文献