A novel fabrication method for the mold insert of microlens arrays by hot embossing molding

This paper reports a simple and novel procedure for fabricating the mold insert of microlens arrays. In this paper, an L₉ experimental matrix design based on the Taguchi method is constructed to optimize the replication quality of molded microlens arrays. The results of the statistical analysis indicate that the processing temperature is the principal parameter affecting the sag height of the molded microlens array. The 200 × 200 arrays of molded microlens, with a diameter of 150 μm, a pitch of 200 μm and a sag height of 31.51 μm have been successfully fabricated. The average surface roughness of the Ni mold insert is 6.916 nm. The average surface roughness of the molded microlens array is 4.608 nm. The processing temperature is the most important factor for the radius of curvature of molded microlens. POLYM. ENG. SCI. 46:1797–1803, 2006. © 2006 Society of Plastics Engineers.     

某医疗器械带金属嵌件塑件的注塑模具设计

以某医疗器械带金属嵌件塑件为研究对象,运用注塑成型技术进行注塑模具设计.针对产品的多规格及系列化特点,创新设计了浇注系统,可以根据需求成型不同规格产品.通过分析塑件的结构特征,设计了组合式型芯、哈夫机构、推出机构,实现嵌件刀片的精准定位,完成塑件成型和自动脱模.将立式注塑机工作台,由一个工位改造成两个工位,既能方便地取...     

微流控法可控构建微尺度功能材料

微尺度功能材料的功能取决于材料结构和组分的精确协同匹配,但如何实现微尺度空间上多样化材料结构的精确调控和功能组分的精确协同定位仍是一大挑战。本文综述了微流控法可控构建新型微尺度功能材料的研究新进展,重点介绍了基于微流控制备的微尺度相界面体系中材料结构和组分的精确协同匹配来设计构建具有独特结构和功能的微尺度功能材料的新策略。首先介绍了以液滴状和液流状微尺度相界面体系为模板,分别可控构建具有多样化结构的功能微颗粒和微纤维的进展;然后介绍了以微通道受限空间内微尺度相界面体系为模板、原位可控构建微通道膜和功能微阀的进展。今后研究应关注于微尺度相界面体系的结构扩展创新及其规模化制备技术。     

辅助阴极对电铸微模芯厚度均匀性的影响

用Ansys有限元软件对微透镜阵列模芯电铸过程中的电场线分布进行模拟分析,研究了辅助阴极的尺寸对电流密度分布的影响,预测了电铸模芯厚度均匀性的变化趋势。分析发现,辅助阴极能提高电铸模芯厚度的均匀性,当框形辅助阴极与母板阴极的边长之比为1.5时,模芯表面的电流密度相对偏差由无辅助阴极时的82.8%降低至10.1%。通过电铸实验对模拟结果进行验证。结果表明,所得铸层厚度偏差可降低到18.89%,与模拟分析结果较为一致。电铸成型所得1 mm厚的微透镜阵列模芯厚度均匀,微观形貌与母板一致,可应用于微注塑成型工艺。     

带嵌件的注塑模具温度场数值模拟

冷却分析（模具温度场计算）是注塑成型计算机辅助工程的关键技术之一,在优化模具设计、提高制品质量方面具有重要作用,本研究提出了采用边界元法建立带嵌件的注塑模具温度场数值模拟的方法,并针对嵌件与模具接触面上的边界条件给定的关键问题,采用耦合边界元法对其转化,将嵌件与模具接触面上的边界条件转移到嵌件与塑件制品的接触面上,使得它的计算可以采用解析法替代原来的差分法,有效提高了分析计算的精度。     

A Simple technique for microfluidic heterogeneous catalytic hydrogenation reactor fabrication

A simple process is described for the facile production of microfluidic reactors with ‘built-in’ metallic catalysts. This approach provides considerable reductions in cost and complexity when compared to existing catalytic chip designs. The process involves the sputtering of catalytic metals into the channels of microfluidic reactors prior to device bonding. The utility of such microreactors as environments for heterogenous catalytic hydrogenations was tested and demonstrated by applying them to the on-chip reduction of butyraldehyde to butanol and benzyl alcohol to benzaldehyde. The use of such ‘built-in’ systems as microreactors for specific processes was shown to have considerable potential for both fundamental research and industrial application.     

A new in situ process in precision casting for mold fabrication

A new in situ process for mold fabrication in precision casting has been developed to decrease processing time and production costs, and produce an environmentally friendly mold, compared with the conventional process. In the new process, the starting powder is fastened by an inorganic binder, whereas the mold in the conventional process takes its form by using an organic binder. The fixing of powders by the inorganic binder is caused by a sol-gel reaction of precursor materials. Therefore, the new mold process is more environmentally friendly and simpler than the conventional process. The inorganic binder system for the in situ process was prepared from a mixture of tetraethyl orthosilicate and poly(dimethyl siloxane) as SiO₂ precursor, and sodium methoxide as Na₂O precursor. The prepared samples show a fracture strength of about 5 MPa, indicating that the in situ process can be applied to the fabrication of molds having high mechanical properties.     

微流控法制备新型微颗粒功能材料研究新进展

微颗粒功能材料在药物传送与控制释放、活性物质封装保护、微反应以及微分离等方面具有极其广泛的应用。相对于传统的微颗粒制备方法,近年来发展起来的微流控技术为可控制备具有不同结构和功能的单分散微颗粒功能材料提供了一个更为优越的技术平台。综述了微流控法制备新型微颗粒功能材料的研究新进展,重点介绍了利用微流控法可控制备具有良好单分散性的球形、非球形、中空型、核-壳型、孔-壳型以及多腔室型功能微颗粒的研究现状。     

Ion dynamics in plasma processing for the fabrication of ultrafine structures

The flux, energy and angular distribution of ions generated from inductively coupled argon plasma were measured, using a gridded retarding field ion analyzer, to investigate the dynamics of ions in the plasma. The ion flux and the ion density at the sheath edge were found to increase with power, but to decrease with pressure. The ion energy was modulated, showing two peaks in the argon plasma, because the ratio of the ion transit time to the rf period was less than or comparable to unity. The peak, mean, minimum, and maximum ion energy decreased with increasing pressure, but were nearly constant as power was varied. The ion angular distributions had a Gaussian distribution peaked at zero angle from surface normal. The full-width-at-half-maximum was increased with increasing both power and pressure. The ion temperature was readily obtained from the ion angular distributions, and the value was in the range of 0.08–0.14 eV, agreeing with typical ion temperature values measured previously in inductively coupled plasmas.     

微流控液滴模板法可控构建功能微颗粒材料

功能微颗粒材料因其微型化和多功能化等优点而在诸多领域具有广泛的应用。微流控技术作为一种崭新的材料制备技术平台,在可控构建功能微颗粒方面展现出了传统制备技术所不具备的独特创造性和优越性。综述了近年来基于微流控液滴模板来可控构建面向化工、医药、储能、环境等领域的多样化功能微颗粒材料的研究新进展。重点介绍了如何基于微流控乳液液滴模板的结构组分设计来理性设计和可控构建多孔结构球形微颗粒、腔室结构球形微颗粒、多样化结构非球形微颗粒等功能微颗粒材料,探讨了基于微颗粒的微观结构和化学组成的耦合来构筑其独特功能特性的设计策略,展望了微流控技术在可控构建新型功能微颗粒材料方面的未来发展趋势。     

Capillary-driven surface-enhanced Raman scattering (SERS)-based microfluidic chip for abrin detection

Herein, we firstly demonstrate the design and the proof-of-concept use of a capillary-driven surface-enhanced Raman scattering (SERS)-based microfluidic chip for abrin detection. The micropillar array substrate was etched and coated with a gold film by microelectromechanical systems (MEMS) process to integrate into a lateral flow test strip. The detection of abrin solutions of various concentrations was performed by the as-prepared microfluidic chip. It was shown that the correlation between the abrin concentration and SERS signal was found to be linear within the range of 0.1 ng/mL to 1 μg/mL with a limit of detection of 0.1 ng/mL. Our microfluidic chip design enhanced the operability of SERS-based immunodiagnostic techniques, significantly reducing the complication and cost of preparation as compared to previous SERS-based works. Meanwhile, this design proved the superiority to conventional lateral flow test strips in respect of both sensitivity and quantitation and showed great potential in the diagnosis and treatment for abrin poisoning as well as on-site screening of abrin-spiked materials.     

微流控模板法制备功能化非球形微颗粒研究新进展

功能化非球形微颗粒在生物医药、吸附、传感与检测等方面具有非常广泛的应用。相对于其他非球形微颗粒制备方法,近年来兴起的微流控技术,由于对微尺度流体具有超灵敏的操控特性,在制备和精确调控微米级功能材料方面具有很大的优势。通过精确控制流体在微尺度通道内的流动和剪切,微流控技术可以实现多种形态和结构的微尺度流体、乳液和纤维的可控构建,为非球形微颗粒的可控制造提供了优良的模板。同时,通过在制备过程中引入功能性材料,这些非球形微颗粒将具备更多的功能,从而极大地拓展和丰富了其应用范围。本文综述了近年来采用微流控技术制备功能化非球形微颗粒的研究新进展,重点介绍了以微流控技术构建得到的微流体、多相乳液及微纤维为模板可控制备功能化非球形微颗粒的研究现状。     

The fabrication of polymer microfluidic devices using a solid-to-solid interfacial polyaddition

It is hard to permanently seal the microfluidic channels made of thermoset polymers without using conventional adhesives. Here, we reported a polyaddition-based mechanism to solve the problem. The method is based on introducing amine groups onto the surface of one material and epoxy groups on another material and enabling the amine–epoxide polyaddition reaction at their closely contacted solid-to-solid interface to establish a covalent and permanent bonding. It was successfully used to permanently seal polydimethylsiloxane (PDMS) microfluidic channels with glass in a scalable and multifunctional fashion and to seal epoxy (SU-8) microfluidic channels with PDMS. This type of interfacial polyaddition can be easily extended to other materials for microfluidic device fabrication and is expected to find some applications in specialty bonding.     

橡胶的环保再生和可逆的加工制造

扼要介绍了一种在常温下。通过机械-化学加工生产再生胶的新方法。可实现胶料的循环、反复利用。该法能耗少、无污染、效率高和掺用比例高。且再生胶料强度为原混炼胶强度的65％-85％左右。可无需添加硫化剂而直接模压成制品。     

三维复杂微流体纺丝芯片的封装研究

为了拓展微流体芯片的应用领域,以一种具有三层结构的多功能集成微流体纺丝芯片为例,利用去离子水和再生丝素蛋白水溶液,比较了环氧树脂粘合剂、硅胶粘合剂以及压敏胶对聚二甲基硅氧烷(PDMS)和纤维素膜的粘合效果,探讨了等离子处理、封装方式等三维复杂微流体芯片的封装技术,实现了多功能集成微流体纺丝芯片的有效封装,对具有类似结构的三维复杂微流体芯片的封装提供参考。     

LLY-1700液压式双模轮胎定型硫化机的研制

介绍了国产首台LLY－1700液压硫化机。该机是具有国际当代水平的高等级液压硫化机,并批量出口法国米其林轮胎公司,获得好评,该机具有生胎对中性好,合模平行度精度高,运动快速平稳,控制系统先进,设备利用率,直接生产率高的特点,能潜代进口产品,具有较高的市场竞争力。     

智能微流控检测芯片的构建及其Pb2+检测性能

通过将具有Pb²⁺响应性的聚（N-异丙基丙烯酰胺-共聚-苯并-18冠-6丙烯酰胺）智能微凝胶与H型微通道相结合,构建了一种能便捷、灵敏、可视化检测水溶液中Pb²⁺浓度的新型智能Pb²⁺检测微流控芯片。该微流控检测芯片主要由软光刻技术构建,并结合紫外光照聚合在H型微通道中原位构建智能微凝胶。基于该微凝胶的Pb²⁺响应性体积相变和H型微通道中的流体流动,该微流控检测芯片能将Pb²⁺浓度信号有效转换为易于检测读取的、可视化的H型微通道中指示液覆盖的指示柱数目的变化信号。通过光学显微镜便捷观察测量指示液覆盖的指示柱数目的变化,实现了对水溶液中痕量Pb²⁺浓度的超灵敏定量检测。该微流控检测芯片为水环境中的痕量Pb²⁺浓度的便捷、灵敏、可视化检测提供了新策略。