Systemic lupus erythematosus with pulmonary hypertension--normalization of pulmonary artery pressure by long-term administration of beraprost sodium

OBJECTIVE: To determine the predictive value of angina pectoris diagnosed by Rose questionnaire for cardiovascular disease among treated hypertensives. METHODS: The cardiovascular experience of 4093 patients who had no history of cardiovascular disease and had been administered the Rose questionnaire for angina in a worksite treatment program was evaluated. RESULTS: Among 2659 men and 1434 women of similar age (53 versus 54 years), the race distribution was 44 versus 31% whites, 27 versus 41% blacks and 29 versus 28% Hispanics. Overall, the prevalence of angina by Rose questionnaire in women (15%) was twice that in men (7%) in all three races, with Hispanics having the highest (20 versus 10%) prevalence. Those with angina (Rose-plus) and those without (Rose-minus) had similar initial and final blood pressures. In 4.0 years of average follow-up study, the crude incidence rates (per 1000 person-years) of the recorded 120 myocardial infarctions and 35 strokes did not differ significantly between Rose-plus and Rose-minus patients, except for myocardial infarction in Hispanic men (20.5 versus 5.9). When myocardial infarction incidence was adjusted for age within each sex-race subgroup, only Rose-plus Hispanic men had a significantly greater relative risk with Rose-minus as referent (relative risk 3.13, 95% confidence interval 1.31-7.50). Overall, in the Cox proportional hazards regression model, angina by Rose questionnaire was not predictive of myocardial infarction after accounting for other recognized risk factors. CONCLUSIONS: The present data suggest that the Rose questionnaire as a diagnostic tool for angina is not predictive of subsequent clinical events among treated hypertensive patients.     

Comparison of methods to assess coronary heart disease prevalence in South Asians

BACKGROUND: Migrants from the Indian subcontinent (South Asian migrants) in the United Kingdom have high mortality from coronary heart disease (CHD) in comparison to the indigenous population. Few studies have assessed the prevalence of CHD in South Asians, and the applicability of conventional survey methods in this population is not known. In this pilot random population survey of South Asian men and women living in West London, the prevalence of CHD as judged by the Rose questionnaire, past cardiac history, cardiologist and resting electrocardiogram were compared. METHODS: Subjects aged 30-64 years from randomly selected households were invited for a cardiological assessment. A lay person administered the Rose questionnaire and recorded the past cardiac history. A cardiologist also made an independent assessment and a 12-lead electrocardiogram was recorded and analysed according to the Minnesota code. RESULTS: Three hundred and seventy-six individuals (192 men and 184 women) were assessed. The prevalence of angina in men and women, respectively, was 3.1% and 4.9% by the Rose questionnaire; 2.6% and 2.2% by past cardiac history; and 4.2% and 0.5% according to the cardiologist. The prevalence of myocardial infarction in men and women, respectively, was 5.2% and 2.2% by the Rose questionnaire, 3.6% and zero by past cardiac history and 3.6% and 0.5% by the cardiologist. Q/QS codes were present in 1.6% men and 0.5% women and ischaemic codes in 13% men and 14% women. Ischaemic changes were not associated with any cardiac history in 72% of men and 92% of women. For a diagnosis of CHD in men, there was poor agreement between the Rose questionnaire and either the past cardiac history or the cardiologist's assessment, but moderate agreement between the past cardiac history and the cardiologist. Agreement was poor between all three methods for a positive diagnosis of CHD in women. CONCLUSION: Current accepted epidemiological methods for assessing CHD prevalence may be inaccurate in South Asians, especially women. Electrocardiogram abnormalities suggestive of ischaemia are common in South Asians and are usually not associated with evidence of CHD. Thus, their value as indicators of CHD is questionable.     

Use of norm groups to adjust student ratings of instruction: A warning.

D. P. Hoyt et al (1973, 1978) recommend the use of norm groups, controlled for class size and student motivation, to adjust student ratings of instruction and make comparisons among teachers more appropriate. The method that Hoyt employs for generating norm groups relies heavily on the use of volunteer Ss. This study made a student evaluation-of-instruction questionnaire available to 169 teachers over a 2-yr period. 69 instructors volunteered to use the questionnaire. Volunteers were compared with nonvolunteers on a previously collected mandatory student evaluation questionnaire. The hypothesis that volunteer teachers' student ratings were reliably superior to the ratings of nonvolunteer teachers was confirmed. The implications for the generation and use of norm groups are discussed. (23 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Treatment of warts with topical pyruvic acid: with and without added 5-fluorouracil

Numerous studies have suggested that epilepsy and asthma may be related conditions. There has, however, been little epidemiologic data published to support this association. We conducted a retrospective study to determine whether the prevalence of epilepsy is increased among children with asthma, and the prevalence of asthma is increased among children with epilepsy, in comparison with the general pediatric population. We reviewed the medical records, at a large city hospital, of two groups of pediatric outpatients: (1) 400 consecutive patients with asthma followed regularly at the asthma and allergy clinic; and (2) 201 consecutive patients with idiopathic epilepsy followed regularly at the pediatric neurology clinic. Patients with a history of birth prior to 36 weeks' gestational age were excluded. Among the 400 cases of asthma, there were three patients with idiopathic epilepsy (prevalence of 0.75%). The prevalence of epilepsy was similar in mild (0.79%) and moderate-to-severe (0.73%) asthma. Among the 201 cases of idiopathic epilepsy, there were 12 patients with asthma (prevalence of 5.97%). Similar percentages of epilepsy patients with and without asthma reported generalized tonic-clonic, complex partial, simple partial, and myoclonic seizures as their predominant type. The prevalence values in this study are consistent with the prevalence of epilepsy and asthma in the general pediatric population. Our findings therefore suggest that idiopathic epilepsy and asthma are not etiologically related or mutually predisposing conditions. Small samples, failure to exclude patients born prematurely, and the equation of electroencephalographic (EEG) abnormalities with epilepsy may account for the results of previous studies.     

Surgical repair for supravalvular aortic stenosis: intermediate to long-term follow-up

The prevalence of different malocclusion features was investigated in 396 6-year-old Icelandic children, using the epidemiologic registration method described by Bj?rk et al. in 1964. Girls were ahead of boys with regard to dental stage (P < 0.01). One or more permanent teeth were congenitally missing in 5% of the children. Postnormal occlusion was found in 27% of the boys and in 31% of the girls, and prenormal occlusion was found in 6% and 5%, respectively. Straight terminal plane at the second deciduous molars was found in individuals with either normal or postnormal occlusion. Thus, it can be misleading to use the relation of the terminal planes as a measurement of the sagittal relation between the jaws. The prevalence of hypodontia was much lower than has been reported previously for Icelandic children.     

Ultrastructure of the taste disc in the red-bellied toad Bombina orientalis (Discoglossidae, Salientia)

To establish the prevalence, with 95% confidence limits, of some of the indicators of coronary heart disease in the rural population of Thiruvananthapuram district, Kerala state, India, we did a field survey on a cluster sample with probability proportionate to size (PPS sample) of 500 households from five villages. Altogether the sample consisted of 1253 individuals who were more than 25 years of age, of which 1130 responded (90%). The survey instruments included the Malayalam translation of the Rose questionnaire, a standard 12-lead electrocardiogram with a battery operated portable electrocardiograph machine, blood pressure measurements using a mercury sphygmomanometer, and routine anthropometric measurements. The prevalence rates estimated were: (a) ECG changes suggestive of coronary heart disease, 36/1000 (95% C.L., 18, 55), (b) Rose questionnaire angina, 48/1000 (95% C.L. 35, 62), (c) definitive evidence of coronary heart disease, 14/1000 (95% C.L., 7, 21), (d) possible evidence of coronary heart disease, 74/1000 (95% C.L., 55, 93). Prevalence of major risk factors were, (a) hypertension by the WHO criteria, 179/1000 (95% C.L., 137, 221), (b) smoking, 219/1000 (95% C.L., 151, 287), (c) diabetes, 40/1000 (95% C.L., 17, 63), (d) obesity, 55/1000 (95% C.L., 6, 104). We have found that objective criteria indicate a lower prevalence of coronary heart disease in rural Thiruvananthapuram district when compared to studies from urban centres in India, but the prevalence of angina by Rose questionnaire is greater.     

Residents' experiences of abuse, discrimination and sexual harassment during residency training. McMaster University Residency Training Programs

OBJECTIVE: To assess the prevalence of psychological abuse, physical assault, and discrimination on the basis of gender and sexual orientation, and to examine the prevalence and impact of sexual harassment in residency training programs. DESIGN: Self-administered questionnaire. SETTING: McMaster University, Hamilton, Ont. PARTICIPANTS: Residents in seven residency training programs during the academic year from July 1993 to June 1994. Of 225 residents 186 (82.7%) returned a completed questionnaire, and 50% of the respondents were women. OUTCOME MEASURES: Prevalence of psychological abuse, physical assault and discrimination on the basis of gender and sexual orientation experienced by residents during medical training, prevalence and residents' perceived frequency of sexual harassment. RESULTS: Psychological abuse was reported by 50% of the residents. Some of the respondents reported physical assault, mostly by patients and their family members (14.7% reported assaults by male patients and family members, 9.8% reported assaults by female patients and family members), 5.4% of the female respondents reported assault by male supervising physicians. Discrimination on the basis of gender was reported to be common and was experienced significantly more often by female residents than by male residents (p < 0.01). Ten respondents, all female, reported having experienced discrimination on the basis of their sexual orientation. Most of the respondents experienced sexual harassment, especially in the form of sexist jokes, flirtation and unwanted compliments on their dress or figure. On average, 40% of the respondents, especially women (p < 0.01), reported experiencing offensive body language and receiving sexist teaching material and unwanted compliments on their dress. Significantly more female respondents than male respondents stated that they had reported events of sexual harassment to someone (p < 0.001). The most frequent emotional reactions to sexual harassment were embarassment (reported by 24.0%), anger (by 23.4%) and frustration (20.8%). CONCLUSION: Psychological abuse, discrimination on the basis of gender and sexual harassment are commonly experienced by residents in training programs. A direct, progressive, multidisciplinary approach is needed to label and address these problems.     

Prevalence of Posttraumatic Stress Disorder in Persons With Spinal Cord Injuries: The Mediating Effect of Social Support.

Objectives: To evaluate the prevalence of posttraumatic stress disorder (PTSD) and to identify risk factors of PTSD in persons with spinal cord injury (SCI). Main Outcome Measures: PTSD and social support were assessed by using the Harvard Trauma Questionnaire (R. F. Mollica et al., 1992) and the Crisis Support Scale (S. Joseph, W. Yule, R. Williams, & B. Andrews, 1993). Participants: One hundred sixty-eight persons with SCI, who were an average of 14 years after injury, filled in the questionnaire. Results: The prevalence of PTSD was 7.1%. Risk factors for PTSD included complete injury, being single, and low level of social support. Conclusions: The prevalence of PTSD after SCI is similar to that in the general population. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The spatial analysis of covariates in a study of environmental epidemiology

Kanawha County, West Virginia, includes a deep river valley with a large population living in close proximity to many chemical manufacturing centres. One study of this area combined an epidemiologic survey of children attending Kanawha County schools with the measurement of the concentrations of 15 volatile organic compounds at each of the 75 elementary schools. Results have been reported by Ware et al. This paper further examines the associations of the concentrations of the ten individual volatile organic compounds related to chemical manufacturing processes with observed lower respiratory symptoms, generalizing the model of spatial variability and measurement error proposed by Donnelly et al. and using semi-variograms to assess the validity of model assumptions.     

Confirmatory factor analyses of academic self-concept scales: Reply to Marsh and Yeung (1997).

H. W. Marsh and A. S. Yeung (1997) criticized the conclusion of S. M. Simpson, B. G. Licht, R. K. Wagner, and S. R. Stader (1996) that children differentiate their perceived ability, near-future expectancies, and distant-future expectancies within academic domains. They argued that Simpson et al.'s questionnaire items and confirmatory factor analytic (CFA) approach were problematic and that their conclusion was inconsistent with research on academic self-concept. The authors of the present article argue that this inconsistency is because items on academic self-concept scales are not adequate for answering the questions addressed by Simpson et al., and that Simpson et al.'s conclusion is quite consistent with 2 other important lines of research. Further, the authors argue that the criticisms of Simpson et al.'s items and CFA approach are unfounded and conclude that Marsh and Yeung inadvertently provided further support for Simpson et al.'s conclusion that current academic self-concept theories should be extended. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Validity of two methods for assessing oral health status of populations

OBJECTIVE: This investigation assessed two methods for estimating epidemiologic indicators of oral health status among children: (1) a visual-only screening, performed independently by a dental hygienist and a registered nurse; and (2) a parent- or guardian-completed questionnaire. The indicators included dichotomous variables measuring dental caries and treatment needs, presence of sealants, injuries to the anterior teeth, and dental fluorosis. METHODS: Following training and calibration, data were collected over an eight-day period in April 1994 among 632 elementary schoolchildren (aged 5 to 12 years) in Monticello, Georgia. Both screening and questionnaire findings were compared pairwise with results from visual-tactile examinations done by a dentist. Validity, represented by sensitivity, specificity, and predictive values, was assessed for screening results from the dental hygienist, the nurse, and the parent-completed questionnaire. RESULTS: Validity was high for screening for caries and treatment needs (> 90% for sensitivity, specificity, and predictive values in a sample having 30% to 40% prevalence). Less valid data--mainly an effect of false negatives--were obtained for fluorosis, injuries, and presence of sealants. No significant difference in validity was observed between the nurse and the dental hygienist. One-third of respondents to the questionnaire did not know if their children needed fillings (a proxy for untreated decay) or had received sealants; only knowledge of restorations was comparable to results from screening. Intraexaminer reliability for the two screeners ranged from 85 to 100 for percent agreement and 0.70 to 0.93 for kappa scores. CONCLUSIONS: Screening by dental hygienists or nurses can provide valid data for surveillance of dental caries and treatment needs. Training for visual assessment of fluorosis and injuries must be improved to diminish the proportion of false negatives. A parent-completed questionnaire is less effective than visual screening for evaluating oral health status in children.     

Verbal encoding effects on the visual short-term memory of learning disabled and normal readers.

Investigated the hypothesis that reading difficulties of learning disabled children are attributable to deficiencies in verbal encoding. Adopting a probe-type serial memory task, 60 normal and learning disabled readers matched on CA (9 yrs old), IQ, and sex were compared on recall performance after pretraining of named and unnamed stimulus conditions. The named condition for normal readers was superior in terms of recall performance. Consistent with the findings of F. Vellutino et al (1972, 1973, 1975), no difference was found in recall of nonverbal stimuli between normal and learning disabled readers. These data suggest that primary reading deficits in learning disabled children are related to verbal encoding deficiencies (visual–verbal integration) and not to deficiencies of visual memory, as suggested by the perceptual deficit hypothesis. (19 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Effect of home environment tobacco smoke on family health.

Replicated and extended earlier research by P. Cameron et al in 1969 that indicated a greater prevalence of respiratory illness among children subjected to tobacco smoke in the home environment. A random phone sample of 2,626 households in Detroit, Michigan and in Long Beach and Pasadena, California, yielded evidence suggesting that (a) children subjected to tobacco smoke in the home environment have a greater prevalence of acute illness when compared to children in smoke-free environments, (b) adult nonsmokers subjected to tobacco smoke in the home environment may have a greater prevalence of acute illness than adult nonsmokers who reside in a smoke-free environment, and (c) respiratory illness rates may be related to air pollution rates in metropolitan areas. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Prevalence, classification, and severity of epilepsy and epileptic syndromes in children

PURPOSE: To determine the point prevalence of active childhood epilepsy in a defined area and evaluate the usefulness of ILAE classification of seizures, and epilepsies/syndromes with special interest in severe epilepsies. METHODS: By using the latest ILAE International Classification of Epileptic Seizures (ICES, 1981) and Epilepsies and Epileptic Syndromes (ICE, 1989), we determined the age- and sex-specific prevalence rates of epilepsy, type of seizures, epilepsies, and recognizable epileptic syndromes, as well as the proportion of severe cases in each seizure/epilepsy/syndrome category in all children 0-15 years of age from a geographically defined area in Finland. All medical records, neurophysiological recordings and available clinical data were reviewed retrospectively. RESULTS: Point prevalence of active epilepsy on December 12, 1992 was 3.94 per 1,000. According to ICES/ICE, we were able to classify 96% of seizures and 90% of epilepsies and syndromes. Generalized seizure and epilepsy/syndrome types were more prevalent in children 0-6 years of age and partial/localization-related in children 6-15 years of age. Epilepsy was intractable in 17% of all cases and correlated significantly with symptomatic etiology and early onset of epilepsy, as well as with additional neuroimpairments. CONCLUSIONS: A considerable number of cases fell into the nonspecific categories of ICE, which limits the value of present epilepsy/syndrome classification in terms of prognosis, prediction, and indication for special investigations in individual cases. A number of intractable cases was relatively low, indicating good prognosis in many childhood epilepsies, especially when additional neuroimpairments are absent.     

A secular increase in the incidence of juvenile diabetes mellitus

Data from a 1973 survey of diabetes mellitus among schoolchildren in Michigan have been analyzed to derive age-specific incidence and prevalence rates. The annual incidence of new cases of diabetes is approximately 20/100,000 children from age four through age 17, with the highest incidence rates at age nine through age 12. The prevalence rates to be expected, if the most recent incidence rates persist, are approximately 50/100,000 at age five, 150/100,000 at age ten, 270/100,000 at age 15, and 325/100,000 by age 18. The incidence rate of diabetes in Michigan children appears to have doubled between 1959 and 1972. Data from Erie County, New York, suggest that this secular trend has been evident since 1949, and data from Norway suggest that the trend could be noted 50 to 70 years ago.     

Dimensions of leadership and leadership style among group intervention specialists.

A questionnaire measuring 26 group leader characteristics investigated by Lieberman, Yalom and Miles (1973) was administered to 204 experienced group leaders distributed geographically throughout the United States. A confirmatory factor analysis of the data revealed no support for the factor structure previously reported by Lieberman et al. Principal-components analysis with varimax rotation was performed, and an eight-factor solution was adopted. The factors pertained to group leader behavior or style (i.e., Cognitive Direction, Affective Direction, Behavioral Direction, and Nonverbal Exercises), leader personal qualities (i.e., Nurturant Attractiveness and Charismatic Expertness), and leader objectives (i.e., Group Functioning and Personal Functioning). (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Lifetime prevalence of "amotivational syndrome" among users and non-users of hashish.

Assessed the lifetime prevalence of amotivational syndrome (AMS) in 237 students at a Central European sports training facility using the criterion for AMS formulated by J. A. Halikas et al (1982). The group was regarded as being highly unlikely to have experienced an AMS. The criterion for AMS was met by 5.9% of the Ss compared to 5.2% of the Ss in the study by Halikas et al who were regular marihuana users. AMS as measured by this criterion was not significantly associated with history of marihuana use. Results cast doubt on the validity of the findings reported by Halikas et al. The AMS hypothesis was not supported. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Age and gender differences in preschool children's identification of the emotions of others: A brief report.

Assessed 113 male and 101 female preschool-age children on the Borke Empathy Scale (1973) to examine gender differences and age differences in Ss' ability to correctly identify the emotions of others. Based on 3 studies by H. Borke (1971, 1973) and R. F. Marcus et al (see record 1979-28401-001), it was hypothesized that (1) there would be a progressive developmental pattern in empathic behavior from the 3rd–5th yr of life and (2) no gender differences would be observed. Significant age and gender differences were observed in Ss' ability to correctly identify others' emotional states associated with happiness, sadness, anger, and fear. A linear progressive improvement was observed between 3 age groups. A significant gender–age interaction revealed that girls were better in correctly identifying others' emotions at age 3 yrs, but by age 5 yrs boys were significantly more correct in their empathic identification of the emotions of others. (French abstract) (PsycINFO Database Record (c) 2011 APA, all rights reserved)     

Underrecognition and undertreatment of asthma in Cape Town primary school children

BACKGROUND: In view of the high local prevalence of asthma, the extent of recognition and appropriate management of childhood asthma was studied in a large suburban area of Cape Town. DESIGN: Cross-sectional study based on random community sample of schools. METHOD: 1,955 parents of sub B pupils from 16 schools completed a questionnaire, followed by: (i) an interview of the parents of 348 symptomatic children; and (ii) bronchial responsiveness testing on 254 children. The final case group consisted of 242 children with reported asthma or multiple asthma symptoms on both questionnaires. Children in whom asthma was acknowledged were compared with those in whom it was not. RESULTS: Overall, any past or current ('ever') asthma was acknowledged by respondents in only 53% of the children, and current asthma in only 37.1%. While most children had received treatment in the previous 12 months, 66.1% of the recognised group were on current treatment (23.2% on daily treatment), compared with 37% of the unrecognised group (3% daily). Salbutamol and theophylline syrups were the most common types of medication, while inhalers and anti-inflammatory medications were underused. Only a minority of parents reported the child ever having used a peak flow meter, or volunteered knowledge of preventive measures. Current treatment, and to a lesser degree recognition of asthma by parents, were more common among children on medical aid and of higher socio-economic status. CONCLUSIONS: These findings suggest that ways need to be found: (i) to increase the use of current asthma treatment guidelines by practitioners; (ii) to provide access to comprehensive care by children not on medical aid; and (iii) to improve education of parents in home management measures such as severity assessment and avoidance of smoking, allergen and dietary triggers.     

Television and aggression: A counterargument.

Cites limitations to the L. D. Eron et al (see record 1973-09034-001) study that suggests that TV violence causes aggression. The Eron et al study dealt with Ss' favorite TV programs and the amount of aggression in them rather than with their actual total amount of exposure to TV violence. (PsycINFO Database Record (c) 2010 APA, all rights reserved)