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1.
Proposed mechanisms of action for ascorbic acid (ascorbate, vitamin C) in the prevention and treatment of cancer include enhancement of the immune system, stimulation of collagen formation necessary for "walling off" tumors, inhibition of hyaluronidase which keeps the ground substance around the tumor intact and prevents metastasis, prevention of oncogenic viruses, correction of an ascorbate deficiency often seen in cancer patients, expedition of wound healing after cancer surgery, enhancement of the effect of certain chemotherapy drugs, reduction of the toxicity of other chemotherapeutic agents such as Adriamycin, prevention of free radical damage, and neutralization of carcinogenic substances. Scottish as well as Japanese studies have pointed to the potential benefit of high dose vitamin C for the treatment of "terminal" cancer. Mayo Clinic studies, however, have contradicted the Scottish and Japanese findings, resulting in accusations of methodological flaws from both sides. Numerous epidemiological studies have pointed to the importance of dietary and supplemental ascorbate in the prevention of various types of cancer including bladder, breast, cervical, colorectal, esophageal, lung, pancreatic, prostate, salivary gland, stomach, leukemia, and non-Hodgkin's lymphoma.  相似文献   

2.
主要研究了废锂电池酸浸液杂质除杂原理,采取“两段酸浸—中和除Fe、Al—絮凝除F—深度除杂”非萃取除杂工艺。在除杂过程中,由于酸浸液含高浓度Ni、Co、Mn离子,中和剂的种类和浓度将影响Ni、Co、Mn的损失率。通过工艺控制及中和剂调试,选择10%CaCO3作为除Fe、Al、F中和剂,Fe、Al、Cu、F含量可分别从0.20、9.76、0.58、1.66 g/L降至0.01、0.02、0.01、29.86 mg/L,达到三元前驱体溶液杂质标准要求。此时,Ni、Co、Mn的损失率分别仅为0.96%、0.04%、0.01%,均在接受范围之内。  相似文献   

3.
Computer analyses to identify correlations between thickness of primary superficial spreading malignant melanoma and eighteen variables previously reported to be related to prognosis were performed on a series of malignant melanomas. The variables that showed statistically significant (less than or equal to 0.05) direct relationships to thickness were level (Clark), elevation of lesion, age of patient, least and greatest diameters of lesion, history of bleeding, ulceration, clinical and histologic stage, anatomic location, pedunculation, and satellitosis. The variables that did not correlate with thickness were clinical diagnosis of regional lymphadenopathy, in-transit metastasis, duration of lesion, sex, history of a previous malignant melanoma, and history of a pre-existing lesion at the site of the development of melanoma. Multiple regression analysis of the factors that showed statistically significant correlation with thickness of the primary lesion revealed a subset of six dominant variables that were most predictive of thickness, namely, level, elevation, largest diameter of lesion, ulceration, histologic stage, and age of the patient.  相似文献   

4.
Basety is a French semantic database of exemplars of 21 categories of objects, with a typicality index associated with each exemplar. These 21 semantic categories are animals, trees, weapons, buildings, flowers, fruits, insects, instruments of music, games, toys, vegetables, mammals, furnitures, birds, tools, fish, occupation, containers, sports, vehicles, and clothes. Basety was made up with two groups of 18-to-30 years old French participants, a first group of three subgroups of 100 participants producing exemplars for 7 × 3 categories while a second group of 80 participants evaluating membership of these exemplars. Typicality was computed as the number of occurrences of the exemplar within the set of the five exemplars participants were first producing. Cronbach's coefficient of reliability indicates an internally consistent scale and number of exemplars is correlated with membership ratings: the more the participants of the first group produced exemplars, the more the participants of the second group agreed on the degree of membership of these exemplars. BASETY appears to be a consistant and valid database for French semantic research. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

5.
Many artists have used the symbol of salt in both religious and profane works, yet very few studies have explored the symbolism of salt as used in works of art. In this study, Panofsky's method has been adopted to evaluate works of art through an organic process articulated into three stages: (1) pre-iconographic, (2) iconographic and (3) iconological. The method was used for (a) religious paintings of the Old and New Testaments and (b) mythological and profane themes. Various salt-cellars were also studied. In particular, the paper examines the following themes: Isaac blessing Jacob, the return of Esau, Samuel consecrating David, the Last Supper, the suppers at Emmaus and at the house of Simon, the birth of St. John the Baptist, the Baptism of Constantine, the prodigal son, Bacchus-Apollo, the nuptial banquet of Love and Psyche, the death of the Cavalier of Celano, the king drinks, the landlord's visit, 'Phitopolis faisant servir des mets en or au roi Pithès', certain still life paintings and various salt-cellars including those of Cellini and Giulio Romano. The paper discusses the works of many artists including Raphael, Leonardo and his school (Boltraffio, Giampietrino, d'Oggiono, Solario), Hendricksz, Corenzio, Jean-Baptiste and Philippe de Champaigne, Damaskinos, Tintoretto, Titian, Romanino, Rubens, Bellini, Bloemaert, Veronese, Sustris, Just of Ghent, Jan Van Hemessen, Poussin, Loir, Giotto, Jordaens, Brueghel and Mimmo Paladino with his enchanted mountain. From the data examined it emerged that salt is a primary iconological presence in various works of art.  相似文献   

6.
Various compounds are known to allosterically modulate the binding of ligands to muscarinic receptors. Most of these compounds have another predominant pharmacological action. Identification of the potent representatives should be useful for the development of allosteric modulators that are specific and highly active. For various reasons, a direct comparison of allosteric potencies on the basis of literature data is difficult. Therefore, a series of compounds was compared with regard to the allosteric delay of the dissociation of N-[3H]methylscopolamine from porcine heart M2 receptors under the following assay conditions: "Na,K,Pi buffer", 4 mM Na2HPO4, 1 mM KH2PO4, pH 7.4, 23 degrees C; "Mg,Tris,Cl,Pi buffer', 50 mM Tris-HCl, 3 mM MgHPO4,pH 7.3, 37 degrees C. Generally, the allosteric potency of the compounds was higher in the Na,K,Pi buffer, compared with the Mg,Tris,Cl,Pi buffer. However, the extent of the potency shift differed, ranging from approximately 2-fold for tacrine to approximately 100-fold for gallamine. The concentration retarding radioligand dissociation to half of the control rate (EC50) served as a measure of allosteric potency. Under both assay conditions, alcuronium was the most potent compound (EC50,Na,K,Pi = 4 nM and EC50,Mg,Tris,Cl,Pi = 55 nM), followed by alkane-bisammonium and bispyridinium compounds containing phthalimido moieties. Gallamine showed intermediate potency (EC50 values of 180 nM and 16,000 nM in Na,K,Pi buffer and Mg,Tris,Cl,Pi buffer, respectively). Obidoxime and hexamethonium, both known to antagonize allosteric actions, revealed submaximal efficacy and low potency (EC50,Na,K,Pi of approximately 100,000 nM). The relevance of these results, regarding the identification of lead structures for the development of new allosteric modulators, is discussed.  相似文献   

7.
采用废酸氧化浸出、CaO焙烧浸出渣、废酸氧化浸出焙砂的火法—湿法联合工艺提取铜冶炼阳极炉精炼渣中的铜。详细研究了废酸直接氧化浸出精炼渣时,浸出温度、液固比、时间、通入空气量对Cu、Fe、As等浸出率的影响,以及焙烧温度、时间、浸出渣与CaO质量比(m(slag)/m(CaO))对Cu、Fe、As等浸出率的影响。结果表明:废酸直接氧化浸出时,浸出温度90 ℃、液固比9 mL/g、时间4 h、每升溶液通入空气量200 mL/min条件下,Cu、Fe、As的浸出率分别为85.32%、68.41%、44.97%。浸出渣与CaO混合后,在温度800 ℃、时间4 h、浸出渣与CaO质量比为5.1的条件下进行焙烧,得到的焙砂经过废酸氧化浸出,精炼渣中的Cu、Fe、As的总浸出率分别达98.10%、69.60%、50.48%。   相似文献   

8.
Breeding animal transports between parts of our institute were used assessing effects of age of animals, of breed, of their functional state and of individual specificity of reaction patterns using peripheral venous blood samples. Increased mean values of Hb, Hk, body temperature, total protein, albumin, FT4, T4, FT3, T3, cortisol, adrenaline and decreased ones of body weight, Pa, Fe, noradrenaline were found after transport stress. Comparing age matched groups of DSB and HF breed higher concentrations of total protein, creatinine, lactate, cortisol, FT4, T3 and FT3 and lower ones of albumin, blood urea and Fe could be observed in animals of DSB breed before and after transport. Strong correlations existed on 14 variables within animals before and after transport stress meaning there could be individual specificity of some blood parameters.  相似文献   

9.
《粉末冶金学》2013,56(5):45-63
Abstract

Large volume expansions accompany the formation of binary alloys of beryllium with uranium, thorium, iron, copper, zirconium, titanium, and vanadium, and of uranium with aluminium, during the sintering of the mixed, cold-compacted elemental powders. No expansion was detected during the sintering of binary mixtures of beryllium with aluminium, silicon, and magnesium, or mixtures of uranium with zirconium, molybdenum, iron, nickel, manganese, and chromium.

When it occurs, expansion is anisotropic, being greatest in the direction of compacting; the degree of anisotropy varies with the constituents and the composition of the alloys. In systems undergoing expansion, the volume expansion/composition graphs exhibit maxima. For a given system the magnitude of the maximum is a function of the shape of compact, the particle size of the powders, and the sintering time and temperature; the composition at which the maximum occurs is sensibly unaffected by these latter variables.

These experimental observations, together with those of other investigators, can be satisfactorily interpreted on the hypothesis that volume expansion is due to the formation of diffusional porosity during sintering.  相似文献   

10.
The prevalence of diabetic ocular complications and the correlation between diabetic retinopathy and systemic factors were examined in 2,300 cases (4,600 eyes) with non-insulin-dependent diabetes mellitus. The prevalence of cataract was 66.7%, of retinopathy 37.0%, of refractive and accommodative change 6.2%, of glaucoma 1.9% (rubeotic glaucoma was 1.0%), of rubeosis iridis 1.5%, of iridocyclitis 0.8%, of extraocular muscle palsy 0.2%, and of ischemic optic neuropathy 0.1%. Duration of diabetes mellitus, HbA1C value, methods of diabetic control, age, diabetic nephropathy, diabetic neuropathy, hypertension, systolic blood pressure, diastolic blood pressure, and arteriosclerosis obliterans were related with diabetic retinopathy. We suggest that the management of diabetic patients needs sufficient attention in the cases with oral administration of medication, insulin therapy, and diabetic nephropathy.  相似文献   

11.
火焰原子吸收光谱法测定合金结构钢中铬、锰   总被引:1,自引:0,他引:1  
利用火焰原子吸收光谱法测定合金结构钢中铬、锰,此方法快速、准确、灵敏度高、精密性好,方法简便,并充分反应了现代仪器的高科技分析手段。合金结构钢使用较为广泛,因此利用原于吸收光谱法测定铬、锰,能迅速有效的达到检测目地的需要。本方法改变了以往化学法操作时间长、步骤多、消耗试剂多的弊病,解决了高氯酸氧化铬对人体的危害及对环境的严重污染。通过对各项做条件试验,优选了最佳仪器测试条件。对干扰元素铁、镍抑制铬的吸收,采用硫酸钠做干扰消除剂,彻底消除了干扰,测定数据稳定可靠。经过对标准样品的测定,重复性好,误差小,回收率达到99~102%,效果令人满意。  相似文献   

12.
在“碳达峰”、“碳中和”的目标背景下,绿色低碳、清洁高效成为资源开采的新要求,也对科学开采这一复杂系统问题的研究提出了新的方向。阐述了矿产资源开采理念的发展演化,综述了近年来国内外在科学开采方面的研究现状,构建了安全、高效、绿色、低碳、经济、科学管理“六位一体”的科学开采体系,丰富了科学开采的内涵和框架。从复杂科学问题的判断标准、科学开采体系的特征两方面进行推断,得出科学开采属于复杂问题,承载科学开采复杂问题的系统是复杂系统。以复杂科学的思路研究科学开采的复杂性,构建科学开采复杂系统模型,从顶层设计、中层连接和底层基础3个层次思考了实现科学开采的新途径,为实现矿产资源的科学开采提供了新的发展方向。  相似文献   

13.
Experimental data on the bulk modulus of elasticity, thermal expansion coefficient, specific heat capacity, specific volume, Grueneisen constant, and atomization energy of the cubic monoxides of Mg, Ca, Sr, Cd, Ba, Eu, Th, U, Pu, Ti, Zr, V, Nb, Ta, Cr, Mn, Fe, Co, and Ni were analyzed. Using six correlation relationships values of unknown properties and adjusted values of known properties at 298 K were calculated.  相似文献   

14.
闫久江  李祥友 《冶金分析》2020,40(12):66-71
针对我国成熟且商业化的便携式激光诱导击穿光谱仪器缺乏,且现有便携设备光谱稳定性和抗干扰性能差的现状,提出并成功开发了一种新型小型化、集成化的便携式激光诱导击穿光谱仪器。采用该仪器成功实现了对24种金属矿石的准确分类和微合金钢样品中Cr、Ni、Si、Cu、Ti、V元素的精准定量分析,其对24种金属矿石的平均分类准确率达到了95.83%,微合金钢中各元素定量分析模型的决定系数R2分别达到了0.993、0.984、0.996、0.990、0.980、0.999,检出限(LOD,质量分数)分别达到了0.0355%、0.0587%、0.0773%、0.0120%、0.0085%和0.0082%,交叉验证的平均相对误差(ARECV)分别达到了5.20%、11.30%、18.18%、9.63%、9.73%、9.17%。结果表明,所开发仪器具备良好的定性、定量分析性能,其为便携式激光诱导击穿光谱仪器的国产化提供了新的解决方案。  相似文献   

15.
Reports the names of the officers, boards, committees, and representatives of the American Psychological Association (APA). The lists of members presented include the Council of Representatives, the Board of Directors, Policy and Planning Board, Committee on Structure and Function of Council, Standing Boards and Committees, Continuing Committees, and Ad Hoc Committees and Task Forces. In addition, a list of organizations that may be of interest to APA members, the list of the officers of APA divisions, as well as lists of affiliated associations are provided. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

16.
17.
对非洲中南部某镍矿石的工艺矿物学特征进行研究,为合理有效利用该镍矿石提供依据,采用X射线荧光光谱分析、多元素分析、X射线衍射和镜下鉴定等方法,分析了矿石的化学成分、矿物组成、嵌布特征、矿石结构构造以及主要金属矿物磁黄铁矿和镍黄铁矿的嵌布粒度等。研究结果表明:该矿石中镍含量高达3.42%,以镍黄铁矿的形式存在;硫化镍矿嵌布粒度较粗,+150 μm粒级含量为38.20%,+75 μm粒级含量达68.58%,但分布不均匀。该矿石镍品位高且含镍矿物嵌布粒度相对较粗,属于易选矿石类型,白云石、滑石等含镁脉石矿物的存在是影响该镍矿分选的主要因素。  相似文献   

18.
以调查区的严格管控区土壤为研究对象,挑选了酸模、龙葵、月季、金盏菊、万寿菊、油牡丹、凤仙花7种植物进行了大田试验,考察超积累植物对土壤中Cd、Pb富集的影响。结果表明,不同植物体内或同种植物体内各部位重金属的含量存在较大差异;酸模、金盏菊、龙葵、月季地上部分重金属含量明显高于地下部分,说明重金属在这几种植物的茎叶里积累较多。金盏菊、凤仙花、万寿菊、龙葵对Cd的富集较强,有利于修复Cd污染的土壤。除凤仙花外,其他6种植物对Cd的转运系数均大于1,对Cd的转移能力由强到弱的顺序依次为酸模、金盏菊,龙葵、油牡丹、月季、万寿菊。就单株而言,积累生物量从大到小依次是酸模、金盏菊、万寿菊、月季;就每亩而言,积累生物量从大到小依次是金盏菊、酸模、月季、万寿菊。综合植物对重金属的富集系数、植物自身的转运系数、整株生物量以及植物的经济价值等考量,万寿菊、金盏菊、月季在修复土壤重金属污染的同时还可兼顾提升经济效益,酸模作为有效降低Cd、Pb含量的重金属修复植物,可推广应用于碱性耕地的重金属污染修复。综上所述,从植物对重金属的富集系数、植物自身的转运系数、整株生物量以及植物的经济价值等综合考量,万寿菊、金盏菊、月季作为修复土壤重金属污染的同时兼顾提升经济,酸模作为有效降低Cd、Pb含量的重金属修复植物,可推广应用于碱性耕地的重金属污染修复。  相似文献   

19.
80 of 100 psychologists who possessed PhDs and were staff members of colleges or universities were randomly selected from the "American Psychological Association 1958 Directory." In order, the highest rated authors were: Freud, James, Hull, Pavlov, Watson, Boring, Skinner, Thorndike, Woodworth, Tolman, Kohler, Lewin, Darwin, Ebbinghaus, Koffka, and Wundt. Books rated with the largest number of points include: James' "Principles of Psychology"; Hull, "Principles of Behavior"; Pavlov, "Conditioned Reflexes"; Freud, "Interpretation of Dreams"; Boring, "History of Experimental Psychology"; and Watson, "Psychology from the Standpoint of a Behaviorist." From Psyc Abstracts 36:02:2AI92W. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

20.
对去除铁、砷、钙、镁后的硫酸镍溶液,采用钠皂化的P507萃取剂分离铜、锌、钴.考察了皂化率、P507体积分数、平衡pH值、相比、时间、温度以及逆流萃取级数对萃取效果的影响.同时考察了负载有机相反萃过程中硫酸浓度、反萃相比、时间对铜、锌、钴反萃效果的影响.结果表明,当萃取有机相组成为35 % P507+65 %磺化煤油,钠皂化率为65 %,相比(VO/VA)为1:1,平衡pH值为4,25 ℃,萃取时间为5 min,经3级逆流萃取,铜、锌、钴的萃取率分别为96.73 %、99.87 %、94.17 %.对负载有机相经过酸性去离子水(pH=3~4)洗涤后,用1 mol/L硫酸溶液,时间为5 min,反萃相比(VO/VA)为1:1.在此条件下,铜、锌、钴的反萃率分别为99.94 %、99.94 %、99.86 %.   相似文献   

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