Applicants for Fellow Status: 1959.

Lists the names of 149 members of the APA who are applying for Fellow status, together with the names of the divisions (in italics) through which they are applying. All of these applicants are applying for Fellow status for the first time through the indicated divisions. Not included on this list are persons already Fellows in the APA who may be applying for Fellow status in additional divisions, nor persons whose names have been previously published as applicants. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Applicants for fellow status: 1962.

Names of 123 members of the American Psychological Association who are applying for Fellow status, together with the names of the divisions through which they are applying, are listed. From Psyc Abstracts 36:02:2AJ95A. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Applicants for Fellow Status: 1961.

Lists the names of 112 members of the American Psychological Association who applied for Fellow status in 1961, together with the names of the divisions through which they applied. The article also provides the deadline for filing applications for initial Fellow status. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Dartmouth Medical School bicentennial

To investigate the regulation of cell-to-cell coupling in myocardial ischaemia, the three-dimensional expression of connexin43 (Cx43) during experimental ischaemia was examined using a confocal laser scanning microscope. After induction of myocardial infarction in rats, serial optical sections were obtained from the left ventricular myocardium at various times (3 h to 60 days after ligation). The expression of Cx43 was detected immunohistochemically with FITC-labelled anti-rat Cx43 antibody. Fluorescent dots of Cx43 remained along the intercalated disc and decreased in number around the infarct up to 12 h after ligation. Cx43-expression disappeared completely within 48 h after ligation. After day 4, and especially on days 8 and 15 after ligation, the edges of the cardiomyocytes bordering the infarcted area manifested numerous sarcoplasmic tentacles that reacted positively to anti-desmin antibody. Distinct expression of Cx43 was observed extensively on the tentacles, although no cardiomyocytes remained viable around them. By day 60 after ligation, atypical expression of Cx43 had disappeared. These findings suggest that ischaemia induces temporally abnormal expression of Cx43, which might be responsible for abnormal conduction around the infarct.     

APA Visiting Psychologist Program: 1974-1975.

Notes that the Visiting Psychologist Program has completed its eighth year of operation under the sponsorship of the National Institute of Mental Health. The program is designed to facilitate the dissemination of up-to-date knowledge generated in recent research findings and to provide for the demonstration of innovations in psychological procedures to mental health professionals in service settings by psychologists who are significantly involved in research, training, and delivery of services. Agencies that received initial visits are listed, with their Visiting Psychologists as well. Agencies and Visiting Psychologists involved in return visits are also listed. The Advisory Committee would like to thank all of those who contributed to the success of the program. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

APA Visiting Scientist Program: 1974-1975.

Notes that the American Psychological Association's Visiting Scientist Program has now completed its fifteenth and last year of operation. Support for the program was provided from contributions from the institutions visited. Because the program is not self-supporting and is no longer receiving funds from the American Psychological Foundation or the American Psychological Association, the program terminates this year. The reports of the visits were very favorable, and the Educational Affairs Office would like to express its appreciation to all of those who contributed to the success of this year's program. A list of institutions and visiting psychologists is provided. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Diagnosis and management of the autonomously functioning thyroid nodule: the Walter Reed Army Medical Center experience, 1975-1996

Skeletal muscle atrophy and weakness are thought to be stimulated by tumor necrosis factor alpha (TNF-alpha) in a variety of chronic diseases. However, little is known about the direct effects of TNF-alpha on differentiated skeletal muscle cells or the signaling mechanisms involved. We have tested the effects of TNF-alpha on the mouse-derived C2C12 muscle cell line and on primary cultures from rat skeletal muscle. TNF-alpha treatment of differentiated myotubes stimulated time- and concentration-dependent reductions in total protein content and loss of adult myosin heavy chain (MHCf) content; these changes were evident at low TNF-alpha concentrations (1-3 ng/ml) that did not alter muscle DNA content and were not associated with a decrease in MHCf synthesis. TNF-alpha activated binding of nuclear factor kappaB (NF-kappaB) to its targeted DNA sequence and stimulated degradation of I-kappaBalpha, an NF-kappaB inhibitory protein. TNF-alpha stimulated total ubiquitin conjugation whereas a 26S proteasome inhibitor (MG132 10-40 microM) blocked TNF-alpha activation of NF-kappaB. Catalase 1 kU/ml inhibited NF-kappaB activation by TNF-alpha; exogenous hydrogen peroxide 200 microM activated NF-kappaB and stimulated I-kappaBalpha degradation. These data demonstrate that TNF-alpha directly induces skeletal muscle protein loss, that NF-kappaB is rapidly activated by TNF-alpha in differentiated skeletal muscle cells, and that TNF-alpha/NF-kappaB signaling in skeletal muscle is regulated by endogenous reactive oxygen species.     

Medical ethics teaching. Report of a National Medical School Survey

Medical ethics teaching was surveyed at American medical schools. Of 107 schools that responded, 97 indicated some kind of medical ethics teaching. This included, however, 19 schools where teaching was only by discussion of ethical issues in courses not primarily identified as ethics courses. Fifty-six institutions (up from 17 in 1972) reported that they conducted special conferences, lectures, or seminars on issues in medical ethics. Specific medical ethics electives were offered in 47 schools; some kind of required course existed at six institutions. The number of faculties with major commitments to medical ethics teaching increased approximately 50% (from 19 to 31). Several schools now have departments or interdepartmental teaching programs with formal structure and permanent staff.     

Cancer incidence and mortality in France in 1975-95

The aims of the European Network of Cancer Registries (ENCR) are to improve the quality, comparability and availability of cancer registry data in Europe. This paper on cancer incidence and mortality in France presents the most recent available data, with short-term projections to 1995, and a commentary based, where possible, on epidemiological research carried out in France. Cancer incidence in men in France increased throughout the study period 1975 to 1995, from 92,000 new cases in 1975 to about 135,000 in 1995. This increase was partly due to the ageing of the French population, but incidence rates have also increased, particularly from 1975 to 1985. The trend appears to be levelling off in the 1990s, with an incidence rate in 1995 of about 482 per 100,000 (this and subsequent rates quoted are standardized to the European Standard Population). Among women, the all-cancer incidence rates also increased during the 1970s and 1980s. Although the rate of increase was less pronounced than in men, the trend is continuing in the 1990s. The estimated age standardized rate in 1995 was 309 per 100,000, representing 104,000 new cases. The main components of these changes in the last decade were, for men, increases in large bowel and prostate cancer, which have been partly compensated for by decreases in oral cavity, larynx and stomach cancer. For women the trend was dominated by the continuing increase in breast cancer with increases also in large bowel and lung cancers. Of the numerically important cancers in women, only stomach cancer has shown a clear decline. The situation in 1995 was that breast cancer remained the predominant cancer affecting women in France, accounting for almost one third of all new cases of cancer diagnosed and one fifth of cancer deaths. The next most frequent cancers in women were those of the large bowel. Regrettably, incidence rates of both breast and bowel cancer are increasing in women. For men in France the most frequent cancers in 1995 were those of the prostate, large bowel and lung, all of which increased in incidence since 1975. Although it is estimated that there will be more newly diagnosed cases of prostate cancer than lung cancer in 1995, the latter will cause many more deaths, particularly of young men.