Female presence during postejaculatory interval facilitates penile erection and 22-kHz vocalization in male rats.

During the postejaculatory interval (PEI), male rats exhibit prolonged immobility, 22-kHz vocalization, and penile erections. To test whether females modulate these behaviors, females were removed after the first or second ejaculation or left in the test chamber. Female presence during the PEI delayed exploratory behavior and facilitated vocalization and erection. Female stimulation of vocalization is consistent with the hypothesis that vocalization has a communicative function, not just a thermoregulatory one. The timing of the effect of females on erection suggests that males are sexually arousable well before they resume copulation. Therefore, erection may be better than vocalization as an indicator of the male's sexual refractoriness. The findings also challenge the conventional view that the PEI comprises absolute and relative sexual refractory periods marked, respectively, by the presence and absence of 22-kHz vocalization. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Effects of selective breeding for infant rat ultrasonic vocalization on cardiac responses to isolation.

Heart rates (HR) and autonomic control of heart period (HP) during maternal separation and isolation were measured at postnatal days (P) 10 and 18 in rat pups selectively bred for high, low, and random rates of infant ultrasonic vocalization. P10 pups displayed no significant line differences in HRs, strong tonic basal sympathetic control of HP and little sympathetic reactivity to isolation, and no evidence of tonic baseline or phasic parasympathetic responses to isolation. At P18, during isolation and recovery, Low HRs were significantly higher compared with Random and High pups. High HRs were significantly higher compared with the Random line in the last third of isolation and through recovery. The higher HRs of Low pups during stress were due to greater parasympathetic withdrawal, but greater sympathetic activation could not be ruled out. Higher HRs in High pups were due to increased sympathetic activation. Thus, increases in HR responses in the selected lines are due to different underlying autonomic processes. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Dopaminergic modulation of kappa opioid-mediated ultrasonic vocalization, antinociception, and locomotor activity in the preweanling rat.

The purpose of this study was to determine whether dopamine (DA) systems modulate kappa opioid-mediated ultrasonic vocalizations (USVs), antinociception, and locomotion in young rats. Seventeen-day-old rats were injected with the kappa agonist U-50,488 (0.0-7.5 mg/kg) and saline, the D?-like receptor agonist R(-)-propylnorapomorphine (NPA; 0. 1 or 1.0 mg/kg), the indirect DA agonist cocaine (10 or 20 mg/kg), or the DA antagonist flupenthixol (0.25 or 0.5 mg/kg). USVs and locomotion were measured for 6 min, with antinociception being assessed with a tail-flick test. Kappa receptor stimulation produced analgesia and increased USVs and locomotion. U-50,488-induced analgesia was potentiated by NPA, whereas U-50,488-induced USVs were attenuated by both DA agonists. NPA and flupenthixol depressed U-50,488's locomotor effects. These results show that DA systems interact with kappa opioid systems to modulate USVs, antinociception, and locomotion in preweanling rats. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The psychological refractory period of stopping.

The author examined whether the act of control of stopping is subject to the psychological refractory period (PRP) and whether stopping causes a PRP for the processing of subsequent stimuli. The task was to execute or to stop a rapid finger tapping. PRP interference was predicted for double-stimulation trials, in which 2 signals to tap or stop were presented in rapid succession. The experiments showed that stopping ongoing action is subject to and produces PRP interference similar to starting. Responses to signals to continue an ongoing action do not produce PRP interference. The results suggest that selection or initiation of new responses, but not mere response choice, constituted the processing bottleneck that caused the PRP in the present task. Further results indicate that the inhibition of not-yet-executed actions, in contrast to action termination, does not suffer PRP interference and that response inhibitions and terminations should be distinguished. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Reflex-inhibiting stimuli and the refractory period of the acoustic startle reflex in the rat.

Previous studies show that if acoustic startle stimuli are presented in pairs, then the reaction to the 2nd stimulus (S2) is reduced, with the size of the refractory decrement determined by the interstimulus interval and the relative intensity of the 1st stimulus (S1). If a neutral stimulus (p) is presented just prior to S1, then the reaction to S1 is similarly inhibited, revealing the phenomenon of prestimulus inhibition. In 2 experiments with male albino Holtzman rats (N = 24) it was found that suppression of the reflex to S2 by S1 was unaffected by prestimulus inhibition of S1 (i.e., reflex amplitudes associated with S2 were identical in pS1-S2 series and S1-S2 series). In contrast, a reduction in the intensity of S1 relative to S2 did reduce the effect of S1 on S2. These data indicate that prestimulus inhibition of the reflex to S1 does not result because the preliminary stimulus attenuates the sensory impact of S1. The inhibitory process may be presumed to have a central locus. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Role of the ultrasonic vocalization of the female rat (Rattus norvegicus) in sexual behavior.

Both male and females rats vocalize ultrasonically during mating. In this article, experiments were done to examine the effects of the female's mating call on rat mating behavior. In the first experiment, females copulated with intact males before and after surgical devocalization. In the second experiment, intact females copulated twice with a male: once when they were able to hear and once when they were temporarily deafened with a medical ear mold. In the third experiment, tape recorded ultrasounds were placed in the presence of devocalized females while they were copulating with intact males. In the control condition, tape hiss was presented. In each experiment, it was observed that the female darted more if communications were disrupted (i.e., female devocalized or male deafened). Playback partially reduced darting to control levels. No other behavior was affected consistently across all experiments. Female calls might facilitate self-regulation of mating behavior, or they might focus the male's attention on her proceptive behaviors. It is also possible that the female calls could alter the stimulus properties of the male's behavior, indirectly affecting her own behavior. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The relationship between attentional blink and psychological refractory period.

This study examined the relationship between attentional blink (AB) and psychological refractory period (PRP) using a conventional AB procedure combined with a requirement of speeded responses to the second target (T2). Experiments 1 and 2 showed that, as with PRP, memory retrieval of targets is not a necessary condition for the occurrence of AB in terms of accuracy and that AB occurred in the speed data. Experiment 3 further indicated that the PRP-like speed data were not due to the first target serving as a warning signal that triggered preparation of responses to T2. Experiment 4 manipulated T2 stimulus intensity to be normal or low. Results showed an underadditive interaction between stimulus intensity and lag position in the speed data, whereas an overadditive interaction was found in the accuracy data, suggesting 2 sources of interference leading to AB: the single-channel bottleneck and resource-limited visual-processing capacity. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Anticipation of rewarding electrical brain stimulation evokes ultrasonic vocalization in rats.

Adult rats emit increased rates of 50-kHz ultrasonic vocalizations (USVs) before receiving social and pharmacological rewards. This study sought to determine whether anticipation of rewarding electrical stimulation of the brain (ESB) would also elicit these vocalizations. In Experiments 1 and 2, rats showed increased 50-kHz USVs before receiving experimenter-delivered ventral tegmental area (VTA) and lateral hypothalamic (LHy) ESB on a fixed time 20-s schedule. In Experiments 3 and 4, rats increased their rate of 50-kHz USVs in response to cues that predicted the opportunity to self-stimulate the VTA or LHy. Interestingly, unexpected termination of either type of ESB evoked 20-kHz, rather than 50-kHz, USVs. In Experiment 5, a cue that predicted daily 1-hr feeding sessions increased 50-kHz USVs, whereas a cue that predicted footshock decreased 50-kHz USVs. These effects could not be explained simply by changes in locomotor activity or general arousal. Together, these findings support the hypothesis that short 50-kHz USVs may selectively index a state of reward anticipation in rats. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The capacity of motor reflex and vocalization thresholds to support avoidance conditioning in the rat.

Unconditioned responses (UCRs) of the rat that predict 1-trial, step-through passive avoidance conditioning were identified. The UCRs examined were spinal motor reflexes (SMRs) and vocalization aftercharges (VADs) generated by tailshock. In Exp 1, SMR and VAD thresholds were determined following systemic administration of saline or morphine sulfate. Exp 2 revealed that the capacity of these tailshocks to support conditioning covaried with the probability that VADs were elicited and were independent of the proportion of SMRs that were generated. This pattern of conditioning was not a consequence of either morphine-induced memory deficits or its induction of state-dependent learning (Exp 3). The results are consistent with the 2-process theories of J. Konorski (1967) and A. R. Wagner and S. E. Brandon (1989) in which the unconditional stimulus is viewed as being composed of separate but interrelated epicritic–sensory and protopathic–emotive attributes. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Reduction of dopamine synaptic activity: Degradation of 50-khz ultrasonic vocalization in rats.

Vocal deficits are prevalent and debilitating in Parkinson's disease. These deficits may be related to the initial pathology of the nigrostriatal dopamine neurons and resulting dopamine depletion, which contributes to dysfunction of fine motor control in multiple functions. Although vocalization in animals and humans may differ in many respects, we evaluated complex (50-kHz) ultrasonic mate calls in 2 rat models of Parkinson's disease, including unilateral infusions of 6-hydroxydopamine to the medial forebrain bundle and peripheral administration of a nonakinesia dose of the dopamine antagonist haloperidol. We examined the effects of these treatments on multiple aspects of the acoustic signal. The number of trill-like (frequency modulated) 50-kHz calls was significantly reduced, and appeared to be replaced by simpler (flat) calls. The bandwidth and maximum intensity of simple and frequency-modulated calls were significantly decreased, but call duration was not. Our findings suggest that the nigrostriatal dopamine pathway is involved to some extent in fine sensorimotor function that includes USV production and complexity. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Serial modules in parallel: The psychological refractory period and perfect time-sharing.

The authors describe ACT-R/perceptual-motor (ACT-R/PM), an integrated theory of cognition, perception, and action that consists of the ACT-R production system and a set of perceptual-motor modules. Each module (including cognition) is essentially serial, but modules run in parallel with one another. ACT-R/PM can model simple dual tasks such as the psychological refractory period (PRP), including subtle results previously explained with executive process interactive control (EPIC, D. E. Meyer & D. E. Kieras, 1997a). The central difference between the theories is that EPIC's productions can fire in parallel, whereas in ACT-R/PM, they are serial. Results from three PRP-like experiments with more demanding cognitive requirements indicate that cognitive processing for the 2 tasks need not overlap. ACT-R's activation-based retrieval processes are critical in accounting for the timing of these tasks and for explaining the dual-task performance decrement. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Online order control in the psychological refractory period paradigm.

The authors examined the role of online order control in the psychological refractory period (PRP) paradigm. In the first 2 experiments, participants switched between color-letter and letter-color orders so that subtask order was isolated as the only element being switched. The results indicated that order switching impaired the 2 PRP responses and modulated the PRP effect. Importantly, these effects were reduced by advance preparation, demonstrating that order representation was activated before the subtasks themselves. Preparation for subtask order did not reflect preparation for hand order, as shown in Experiment 3. In addition, there was no evidence that subtask order information dissipated between trials. The relevance of the results to theories of the PRP paradigm and task switching is discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Backward response-level crosstalk in the psychological refractory period paradigm.

Bottleneck models of psychological refractory period (PRP) tasks suggest that a Task 1 response should be unaffected by the Task 2 response in the same trial, because selection of the former finishes before selection of the latter begins. Contrary to this conception, the authors found backward response-level crosstalk effects in which Task 2 response force requirements influenced the force-time dynamics of Task 1 responses. Specifically, Task 2 required a hard or soft keypress response. Task 1 responses were harder when the upcoming Task 2 response was to press hard rather than soft, suggesting some activation of Task 2 response parameters before Task 1 processing reached the final ballistic motor output stage. A 3rd experiment using a flankers paradigm showed that this effect did not arise from automatic activation of responses by the stimuli associated with hard and soft responses. This backward response-level crosstalk extends previous findings of backward crosstalk in the PRP paradigm by showing that crosstalk can affect motor output as well as response time and can arise even when the 2 tasks being performed are not semantically related. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Influence of gonadal hormones and sexual behavior on ultrasonic vocalization in rats: I. Treatment of females.

Ultrasonic vocalizations were measured when male Long-Evans rats were placed with ovariectomized females that had experienced various hormonal and behavioral treatment. In Exp I, 18 males were tested with females in each of the following conditions: nonestrous (OVX), estrogen treated (E), estrogen and progesterone treated (EP), and estrogen and progesterone treated and given 2 intromissions from a stud male prior to testing (EPI). Control conditions included clean cage (CL) and cage soiled by an estrous female (SOI). The treatments differed in effect on rate and maintenance of vocalization, in the order of greatest to least: EP, E, EPI, and OVX (equal), SOI, and CL. In tests in which males produced a high rate of vocalization, some males with short intromission latencies shifted from the normal 50-kHz pulse to a 22-kHz pulse. In Exp II, the effect of the female's vocalization and movement on the rate of and latency to vocalization was measured. 21 males were presented with each of the following stimulus conditions: estrous female with red light (EP), estrous female without red light (EP dark), estrous anesthetized female (EP anes), and nonestrous anesthetized female (OVX anes). Effects on vocalization of various treatments were in descending order: EP and EP-dark (equal), EP anes, and OVX anes. Data suggest that the 50-kHz vocalizations constitute a graded response influenced by the female's hormonal and sexual condition. (16 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Influence of gonadal hormones and sexual behavior on ultrasonic vocalization in rats: II. Treatment of males.

Male Long-Evans rats were tested with estrous female rats in a divided cage to determine whether ultrasonic vocalizing varies as a function of recent sexual behavior or hormonal condition. In Exp I, when males were tested after 3 intromissions, a short latency to vocalization and a high rate of 50-kHz pulses occurred. 40% of the males changed their vocalization to 22-kHz pulses. With sexually fatigued males, long vocalization latencies and low vocalization rates were observed, and no males shifted to 22 kHz. Rates were intermediate with control males. In Exp II, a decline in vocalization rate occurred following castration of male rats compared with sham-operated controls. In both experiments the male nosed the screen divider during high-rate ultrasound production, maximizing contact with the female. Darting by females appeared only when ultrasonic pulse rates were high. The abrupt shift from 50- to 22-kHz vocalizing was characteristic of males with short intromission latencies. Data suggest that gradation of vocalization is correlated with the sexual readiness of the male and that vocalization may facilitate female darting behavior. (25 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The psychological refractory period: Evidence for age differences in attentional time-sharing.

Reports 2 psychological refractory period (PRP) experiments in which the stimulus onset asynchrony (SOA) between Task 1 and 2 was 150, 250, 600, and 1,100 msec for both younger and older adults. H. Pashler's (1994) response-selection bottleneck theory predicts that SOA manipulations should not affect Task 1 performance, but that reaction time (RT) for Task 2 should increase as the SOA between the 2 tasks decreases (i.e., the classical PRP effect). In Exp 1, older adults showed a larger PRP effect, although Task 1 RT was affected by SOA, suggesting that Ss were grouping their responses on some trials. That is, Ss were holding their response for Task 1 until they had completed processing Task 2, and then they responded to both tasks almost simultaneously. However, a subset of Ss who showed no evidence of response grouping on Task 1 continued to show a larger PRP effect for older adults on Task 2. In Exp 2, older adults continued to show a larger PRP effect for Task 2, and Task 1 performance was unaffected by SOA. Findings provide evidence that older adults exhibit a decrement in time-sharing at the response-selection stage of processing. Results suggest that attentional time-sharing needs to be added to the list of topics examined in aging research on varieties of attention. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The psychological refractory period effect following callosotomy: Uncoupling of lateralized response codes.

A callosotomy patient was tested in 2 dual-task experiments requiring successive speeded responses to lateralized stimuli. The patient showed a robust psychological refractory period (PRP) effect. Three aspects of the data indicate that, unlike for the control participants, the PRP effect for the split-brain patient should not be attributed to a response selection bottleneck. First, the patient did not show an increase in reaction time (RT) when the 2 tasks required responses from a common output system compared with when different output systems were used. Second, inconsistent stimulus-response mappings for the 2 tasks increased RTs for the control participants but had minimal effect on the performance of the split-brain patient. Third, the consistency manipulation was underadditive with stimulus onset asynchrony but was additive or overadditive for the normal participants. These results suggest that the persistent PRP effect following callosotomy should be attributed to a bottleneck associated with response initiation, a strategy adopted to comply with the task demands, or a combination of these factors. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Social memory of the male laboratory rat.

Used duration of social-investigatory behavior by 36 mature male Long-Evans rats as a measure of individual recognition in 5 experiments to assess social memory. In Exp I, the duration of social investigation during a 2nd exposure to the same juvenile (n?=?12) was directly related to the length of the interexposure interval. In Exp II, Ss were exposed to the same or different juvenile 10 min after an initial 5-min exposure to a novel juvenile; reexposure to the same juvenile elicited significantly less social investigation than an exposure to a different juvenile. Exps III and IV demonstrated that following a 5-min introductory exposure, social memory of the juvenile was relatively brief in comparison with that of mature Ss. Exp V revealed a retroactive interference effect on recently acquired memory for an individual: 12 mature Ss exposed to interpolated social experience engaged in significantly longer investigation of a juvenile than those with no interpolated social experience. The combined results suggest that (1) the rat normally engages in spontaneous learning of individual identity and (2) social memory may be a significant aspect of complex social interactions. (16 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Aging and the psychological refractory period: Task-coordination strategies in young and old adults.

The apparently deleterious effect of aging on dual-task performance is well established, but there is little agreement about the source of this effect. Studies of the psychological refractory period (PRP) indicate that young adults can flexibly control dual-task performance through task-coordination strategies. Thus, the performance of older adults might differ from young adults because older adults use different task-coordination strategies. To test this hypothesis, the executive-process interactive control (EPIC) architecture was applied to quantify the reaction time data from two PRP experiments conducted with young (age 18–26) and older (age 60–70) adults. The results show that participants' ability to coordinate the processing of two tasks did not decline with age. However, dual-task time costs were greater in the older adults. Three sources for this increase were found: generalized slowing, process-specific slowing, and the use of more cautious task-coordination strategies by the older adults. (PsycINFO Database Record (c) 2010 APA, all rights reserved)