Perception of social interactions in depressed psychiatric patients.

20 21–61 yr old depressed females, 20 depressed Ss in remission, and 20 control Ss were shown videotapes of positive (involving praise), negative (involving criticism), and neutral social interactions. Half of the Ss in each group were instructed to imagine the interactions being directed toward them, and half were instructed to imagine the interactions being directed toward another person. Ss rated each interaction on 11 semantic differential scales. Following a principal components analysis with varimax rotation, analysis of component scores indicated that depressed Ss rated negative interactions lower (i.e., in a more socially undesirable way) than controls only when the interactions were directed toward them. The question of whether or not the perception of negative interactions by depressed persons is distorted is discussed. (8 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Short stature, psychomotor retardation, and unusual facial appearance in two brothers

Described here are clinical, radiological, and morphological studies of two brothers with an apparently previously undescribed mental retardation syndrome.     

Diazepam reinforcement in anxious patients.

The reinforcing effects of diazepam were examined in 4 female patients with generalized anxiety disorder but without histories of drug abuse. Under double-blind conditions, patients were given medication capsules containing either 4 mg diazepam or placebo that they could use "as needed" for anxiety. After a 1-week sampling period for each medication, participants repeatedly chose which medication they preferred over the next 4 weeks. Reinforcing effects of diazepam were demonstrated in 3 participants who showed exclusive diazepam preference. The results suggest procedures whereby drug self-medication behavior may be studied in an outpatient environment. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Conformity and achievement-related characteristics of depressed patients.

Conformity and achievement-related characteristics of 10 hospitalized depressed patients and 11 matched acute schizophrenics were studied in an Asch-type conformity situation, and by the use of self-report inventories. It was found that in the conformity situation, depressed Ss showed a greater tendency to conform to social pressure than did the controls. When conformity and achievement were assessed by the use of self-reports, the results were either nonsignificant or opposite to those found in the conformity situation. The results were compared with recent theory and research dealing with cyclical affective disorders. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Cognitive complaints in elderly depressed and pseudodemented patients.

The cognitive complaints of 11 patients with depressive pseudodementia were compared with those of 22 patients with depression alone. Pseudodemented subjects were defined as depressed inpatients showing reversible cognitive impairment as measured by the Mini-Mental State Examination (MMSE); subjects with depression alone had no such impairment. For each group, cognitive complaints were highly correlated with depressive symptoms and were not related to MMSE scores. The pseudodemented group had significantly higher cognitive complaint scores, complaining more of difficulties with concentration and recent memory. Groups did not differ significantly in complaints of difficulties with remote memory. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Speed in test performance in depressed patients.

Compared the performance of 2 groups of nonschizophrenic, nonorganic, psychiatric patients—25 depressed (mean age 41.4 yrs) and 25 nondepressed (mean age 37.8 yrs) Ss—on several tests, including the Quick Test, the WAIS, and 10 speed tests and measures of ambiguous figure reversal rates. The 2 groups of Ss were matched for general psychopathology, sex, age, and education. No difference in the performance on power-cognitive (i.e., intelligence) tests was found. Depressed patients performed more slowly on psychomotor speed tests, confirming an earlier study comparing depressed patients and normal controls. Findings generally confirm those of the 1st author et al (1972) and those of several earlier studies summarized by W. R. Miller (see record 1975-20082-001). (18 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Attributional style among depressed patients.

Male depressed unipolar patients (n?=?30) were more likely to attribute bad outcomes to internal, stable, and global causes than were nondepressed schizophrenics (n?=?15) and nondepressed medical patients (n?=?61). Also, the depressed patients were more evenhanded in their attributions for good and bad events than the other patients. These results support the existence, in clinical depression, of the depressive attributional style postulated by the reformulated learned helplessness model and indicate that it is not a general characteristic of psychopathology. (31 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Personality and family functioning in families of depressed patients.

In this cross-sectional study, the authors attempted to identify correlates of family functioning in 86 couples with a depressed member during the acute phase of the patient's depression. Demographic variables, psychiatric status, and personality traits of both the patient and spouse were investigated as potential predictors of family functioning. Regression analyses indicated that lower levels of personality pathology in the patient, higher levels of patient conscientiousness, and less psychological distress in the spouse were associated with healthier family functioning. Future research implications and clinical importance of these findings are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Communication and intimacy in the marriages of depressed patients.

Marital discord is common among depressed patients. To explain the concurrence of depression and marital discord, it was hypothesized that depressed patients and their spouses have weak relationship-coping abilities, specifically communication, problem solving, and capacity for intimacy. 17 depressed patients and their spouses were compared with 17 control couples on a communication task, an intimacy interview, and self-reports of marital satisfaction. Results indicated that, compared with control Ss, the depressed patients and their spouses (1) reported greater marital dissatisfaction, (2) demonstrated poorer communication and problem-solving ability, and (3) were more likely to have an impaired capacity for establishing and maintaining intimacy. The implications for understanding the development of depression and marital discord are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Short-term outcomes of detected and undetected depressed primary care patients and depressed psychiatric patients

The aims of this study were to determine whether detection of major depression in primary care was associated with improved outcome, and to compare the 4.5 month outcomes of detected and undetected depressed primary care patients and depressed psychiatric patients. Primary care patients with major depression were recruited from the practices of 50 family physicians in Southeastern Michigan using a two-stage selection procedure employing the Center for Epidemiologic Studies-Depression Scale (CES-D) and the Structured Clinical Interview for DSM-III-R (SCID); clinician detection of depression was ascertained by response to a direct query on a rating form. Depressed patients seeking treatment in an outpatient psychiatric setting also received the CES-D and the SCID. Data on patient demographics and clinical characteristics were obtained for both primary care and psychiatric patients. Initial and 4.5 month scores on the Hamilton Depression Rating Scale (HAM-D) were obtained for 34 undetected and 25 detected depressed primary care and 55 depressed psychiatric patients. Improvement in depression over time was assessed by the change in HAM-D scores over the 4.5 months. The three groups did not differ in initial severity. Both psychiatric and undetected primary care patients showed significant improvement at 4.5 months, whereas detected primary care patients did not improve. At 4.5 months there were no differences in mean HAM-D scores between undetected, depressed primary care patients and depressed psychiatric outpatients. This result did not change after controlling for age and severity of depression at initial presentation, nor did it change after exclusion of cases of mild depression to control for a possible "floor effect." However, differences among groups in the stage of depressive episodes may have affected this comparison. These findings suggest that an exclusive focus on increasing detection of depression in primary care patients is unlikely to improve outcomes, and that undetected depression among primary care patients does not necessarily represent poor quality of care. Although depressed psychiatric patients in this study had better outcomes than detected depressed primary care patients, the presence of unmeasured differences among groups in the stage of the depressive episode makes it impossible to determine whether treatment of depression by psychiatrists is superior to that provided by primary care physicians. These findings should stimulate efforts to examine a more comprehensive model for detection and treatment of depression in primary care.     

Negative and positive cognition in depressed and nondepressed chronic-pain patients.

Examined negative and positive automatic thoughts and attributional style in 60 men (aged 21–64 yrs) who were depressed chronic-low-back-pain (CLBP) patients, nondepressed CLBP patients, or healthy controls. Ss completed measures that included the Attribution Style Questionnaire and the Automatic Thoughts Questionnaire (S. D. Hollon and P. C. Kendall; see record 1981-20180-001). Depressed Ss exhibited significantly more negative automatic thoughts than nondepressed Ss and controls. Nondepressed Ss reported significantly more positive automatic thoughts than did depressed Ss and controls. No significant differences were found for attributional style. Different cognitive-behavioral interventions might be considered for depressed and nondepressed CLBP Ss. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Expressed emotion and causal attributions in the spouses of depressed patients.

High levels of expressed emotion are thought to be related to the attributions relatives make about the causes of a patient's illness and problem behaviors. Causal attributions occurring during spontaneous speech in 43 spouses of depressed patients were examined. Consistent with theoretical prediction and with previous research in schizophrenia high critical spouses were more likely than low critical spouses to attribute patients symptoms and negative behaviors to factors that were controllable by and personal to the patients. High critical spouses also made more attributions that implied that they held patients responsible for their difficulties. Although predictive of spouses criticism these attribution dimensions did not predict patient relapse. The results suggest that causal attributions are important for understanding spouses criticism but are of limited predictive validity with respect to depressive relapse. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Psychiatric history and symptom differences in black and white depressed patients.

Compared 159 black psychiatric patients with 555 white patients on a battery of social, personality, and psychiatric history variables, as well as presenting symptoms. In making these comparisons, race differences in age, social class status, and sex were controlled. Both black and white depressed patients were remarkably similar on presenting symptoms, especially the core symptoms of depression, when the groups were equated or controlled for age and social class differences. However, some differences did emerge on a number of hostility variables. There was a greater tendency toward negativism and the introjection of anger in blacks than in whites. In addition, depressed black males indicated that they were more likely than their white counterparts to strike back, either verbally or physically, when they felt their rights were being violated. There was also a very high incidence of suicide threats or attempts among the black males. (17 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Size of figure drawings of psychotically depressed patients.

The size of human figure drawings of a psychotically depressed group was compared with those of nondepressed controls. The effects of mood change on the drawings of the depressed group following treatment were also examined. Results fail to support a relationship between depression and size of drawing. Changes in mood in patients who improve after treatment for depression are not reflected in subsequent figure drawings. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Sentence perception and distractibility in schizophrenic, manic, and depressed patients.

Previous research with schizophrenics suggested that distraction may have its primary effect on controlled information processing. To explore this hypothesis, 8 schizophrenics, 8 manics, 8 depressives, and 8 normal Ss (all Ss were aged 18–45 yrs) were asked to shadow short stories in both the presence and absence of a competing message and to answer questions afterward about the content of the shadowed message. The shadowing performance of all 3 patient groups was equivalent to that of normal Ss and was not affected by distraction. Shadowing errors of commission indicated that schizophrenics did use semantic and syntactic information to anticipate words in the relevant message, but the schizophrenics also inserted more semantically irrelevant words than any of the other 3 groups. Distraction did interfere with the schizophrenics' ability to recall the content of relevant passages, but not with the performance of the other 3 groups. Data indicate that distraction may have a specific rather than general influence on controlled information processing or that distraction may reduce schizophrenics' overall capacity to handle information in short-term memory. The analysis of shadowing errors suggested that performance on such laboratory tasks may be closely related to the verbal communication problems encountered by many schizophrenic patients, but also that these symptoms may not be a simple function of selective attention difficulties. (30 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Psychotherapy with depressed elderly patients: Research considerations.

There is general agreement that depression is the most common functional psychiatric disorder among the elderly, affecting 7–21% of the population. Since so many of the elderly, especially the depressed elderly, suffer from physical disorders that complicate or contraindicate drug therapy, psychotherapy is potentially a highly desirable treatment modality for many depressed persons in the upper age groups. And yet, elderly people are generally excluded from psychotherapy studies for a variety of methodologial, practical, and ethical reasons. As psychotherapy researchers begin to turn their attention to the treatment of the elderly patient, a number of ethical issues and problems of design and implementation of research with this population must be addressed. The present article explores the issues of patient homogeneity, external validity, internal validity, choosing and implementing specific treatment modalities, therapist experience and attitudes, therapist age, reliability and validity of measures, and problems obtaining follow-up information when studying treatment of depressed elderly patients. (35 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Clinical and CNS effects of oral and I.V. Thyrotropin-releasing hormone in depressed patients

Both oral and intravenous TRH produce systematic alterations in brain function of depressive patients as determined by scalp-recorded computerized cerebral biopotentials (computer EEG). The computer EEG (CEEG) profiles of both formulations are not only very similar to each other, but also resemble the CEEG profiles of psychostimulant compounds (Bio-availability). As in CEEG findings, TSH plasma levels also indicate that oral TRH is indeed an active compound. Although some "antidepressive" effects were observed after both formulations, they were not present in every patient, and it was not always the case after repetitive TRH administration, nor were the effects on depressed mood too impressive. On the other hand, in almost all patients certain behavioral effects of TRH were seen which related to "life instincts" and "life performance". The increase of interest, desire and drive for work, food and sex was one of the most striking findings, particularly after intravenous TRH. This may be responsible for the "antidepressive" effects of TRH in patients in whom depression may be the result of an inhibition of "instinctive" functions.