稀土硝酸盐与希夫碱邻香兰素缩丙氨酸盐及邻菲咯啉三元配合物的合成与表征

合成了稀土硝酸盐与希夫碱邻香兰素缩丙氨酸盐(以KHL表示)及邻菲咯啉的三种固体三元配合物。通过元素分析、差热-热重、红外光谱、紫外光谱及摩尔电导分析等手段,确定配合物的组成为［RE(L)(Phen)(H2O)］NO3,(RE=Y,Nd,Sm)。并对它们的配位方式及某些性质进行了研究。     

Synthesis, Characterization and Antibacterial Properties of Rare Earth (Ce3+, Pr3+, Nd3+, Sm3+, Er3+)Complexes with L-Aspartic Acid and o-Phenanthroline

Five novel ternary complexes of rare earth ions with L-Aspartic acid (Asp) and o-phenanthroline (Phen) were synthesized in ethanol aqueous solution. Their compositions were characterized by elemental analysis, molar conductance, FT-IR, Raman, UV-VIS and TG-DTA. The compositions of the complexes were confirmed to be: RE(Asp)3PhenCl3·3H2O (RE: Ce3 , Pr3 , Nd3 , Sm3 , Er3 ). The antibacterial activity test shows that all these complexes exhibit excellent antibacterial ability against Escherichia coli, Staphylococcus aureus and Candida albicans. The antimicrobial spectrum of the complexes are broad.     

Synthesis, Characterization and Fluorescence Properties of Europium, Terbium Complexes with Biphenyl-4-Carboxylic Acid and o-Phenanthroline

Two series of solid complexes of europium and terbium with biphenyl 4-carboxylic acid and phen were synthesized and characterized in this report. Their elemental analysis, molar conductivities and TG-DTA studies indicate that the complexes have the composition of Eu(phen)L3·1/2H2O, Eu0.5RE0.5(phen)L3·1/2H2O; Tb(phen)L3·H2O and Tb0.5RE0.5(Phen)L3·1/2H2O. (RE=Y3 , La3 and Gd3 ; L=biphenyl 4-carboxylic acid; phen=o-Phenanthroline). The studies of their IR, UV 1H NMR and molar conductivities demonstrate that biphenyl 4-carboylic acid is bounded with RE(Ⅲ) ion. Rare earth ions coordinate with two nitrogen atoms of phen molecules directly in these rare earth complexes. The fluorescence spectra and fluorescence lifetimes of the rare earth complexes show that the fluorescent intensity and lifetime of a series of europium complexes are longer than those of the series of terbium complexes as having the some ligands. There are better fluorescent intensity and lifetime of hetero-nuclear rare earth complexes than homo-nuclear rare earth complexes for europium complexes. The fluorescence emission intensity of Eu3 is raised by inert fluorescent rare earth ions (Y3 , Gd3 and La3 ), but in Tb3 hetero-nuclear rare earth complexes the intensity of Tb3 ions are quenched by the inert fluorescent rare earth ions.     

Synthesis, characterization, and biological properties of nano-rare earth complexes with L-glutamic acid and imidazole

Four nano-rare earth ternary complexes of L-glutamic acid and imidazole RE（Glu）3ImCl3·3H2O （RE=Ce^3＋, Pr^3＋, Sm^3＋, Dy^3＋, Glu= L-glutamic acid, and Im=imidazole） were synthesized. Their composition was characterized with elemental analysis, IR, and molar conductance. The TEM image indicated that the complexes were regular shaped and the length was about 30-60 nm. The antibacterial activity test showed that all these complexes exhibited better antibacterial ability against Escherichia coli, Staphylociccus aureus, and Candida albican （MIC were about 180, 100, and 310 μg/mi, respectively） and could be considered as broad-spectral antimicrobial. Their antitumor activity in vitro against leukemia K562 cells was measured using the MTr method. The results indicate that the four complexes possess strong inhibi- tion effect on leukemia K562 cells. An approximately linear relationship is discovered between the relative inhibition rate and concentration, with the correlation coefficients R〉0.7 and P〈0.05, which is considered statistically significant.     

稀土-苯氧乙酸二元、三元配合物的表征及其对植物铅、镉污染的影响

合成了六种稀土苯氧乙酸的二元、三元配合物,其通式为RE(POA)3、RE(POA)3Phen、RE(POA)2hq(RE=L a、Y;HPOA=苯氧乙酸;Phen=邻菲罗啉;Hhq=8-羟基喹啉)。研究了配合物在不同溶剂中的溶解性及摩尔导电性,用IR、UV、DTA等方法研究配合物的结构特点,并对L a(POA)3对植物铅、镉污染的影响做了初步的探讨。     

双水杨醛1,6-己二胺希夫碱轻稀土配合物的合成和表征

合成并表征了双水杨醛缩 1,6 己二胺希夫碱配体 (C2 0 H2 4 N2 O2 ,以L表示 )与轻稀土Ln3 的 7种新的固体配合物 [LnL2 ](NO3) 3(Ln =La、Ce、Pr、Nd、Sm、Eu、Gd)。利用元素分析、摩尔电导、红外光谱、电子光谱、X射线衍射物相分析、热分析方法进行表征。中心金属离子Ln3 与希夫碱配体中的亚胺氮和酚羟基中的氧发生配位 ,配位数为 8。     

Synthesis, Characterization and Activity of Rare Earth Complexes with Schiff Base From 2,6-Diformylpyridine N-Oxide and 4-Amino-antipyrine

Six new rare earth complexes with Schiff base from 2,6-diformylpyridine N-oxide and 4-amino-antipyrine were synthesized. These complexes with general formula REL(NO3)3(RE = La, Pr, Eu, Tb, Er, Y) were characterized by elemental analysis, IR, UV, molar conductance measurements and antimicrobial activity.     

Synthesis,characterization, biological activities and luminescent properties of lanthanide complexes with [2-thiophenecarboxylic acid, 2-(2-pyridinylmethylene)hydrazide] Schiff bases ligand

A Schiff base L [2-thiophenecarboxylic acid, 2-(2-pyridinylmethylene)hydrazide] with its lanthanide metal complexes was synthesized. These complexes were characterized by elemental analysis, molar conductivity measurements, spectral analysis(NMR, FT-IR, and UV-Vis), luminescence and thermal gravimetric analysis. The Schiff base ligand was a tridentate chelate and coordinates to the central lanthanide ion with 1:2 metal:ligand ratio. The conductivity data showed a 1:1 electrolytic nature with a general formula [LnL_2(NO_3)_2]NO_3. The luminescence emission properties for Sm, Tb, and Eu complexes were observed and showed that the ligand L could absorb and transfer energy to Sm(III), Tb(III) and Eu(III) ions. The complexes possessed a good antibacterial activity against different bacterial strains. In addition, the scavenging activity of the Ln(III) complexes on DPPH was concentration dependant and the complexes were significantly more efficient in quenching DPPH than the free Schiff base ligand.     

Synthesis and Application of Lanthanide Complexes with Schiff Base of Pridoxylidence-Glycine

Ｔｈｅｈａｒｍｆｕｌｎｅｓｓｏｆｈｅａｖｙｍｅｔａｌｅｌｅｍｅｎｔｓｏｎｐｌａｎｔｓｉｓｏｎｅｏｆｔｈｅｓｅｒｉｏｕｓｅｎｖｉｒｏｎｍｅｎｔａｌｐｒｏｂｌｅｍｓｏｆｔｈｅｍｏｄｅｒｎｗｏｒｌｄ .Ｉｎｒｅｃｅｎｔｙｅａｒｓ ,ｔｈｅｓｔｕｄｙｏｎｔｈｅｍｉｓａｌｓｏｏｎｅｏｆｖｅｒｙａｃ ｔｉｖｅｒｅｓｅａｒｃｈｐｒｏｊｅｃｔｓｉｎｐｌａｎｔｐｏｌｌｕｔｉｏｎｅｃｏｌｏｇｙｆｉｅｌｄｓ[1～ 6 ] .ＬａｎｔｈａｎｉｄｅｃｏｍｐｌｅｘｅｓｗｉｔｈｔｈｅＳｃｈｉｆｆｂａｓｅａｒｅａｃｌａｓｓｏｆｃｏｍｐｏｕ…     

Synthesis, Characterization and Luminescent Properties of Complexes of Rare Earth Nitrates with 2,2′:4′,4″:2″,2-Quaterpyridine

The rare earth nitrate complexes with 2,2′:4′,4″:2″,2-quaterpyridine (L) were prepared in ethylacetate. These new complexes with the general formula [RE(NO3)3L]*H2O (RE = La, Pr, Eu, Tb, Er, Y) were characterized by elemental analysis, IR spectra, thermal analysis and molar conductance measurements. The luminescence properties of these complexes were also studied.     

Synthesis, Characterization and Fluorescence of Rare earth Nitrate Complexes with Triaza-crown Ether Derivative

Sinceaza crownethershowsspecialcoordinationpropertiestotransitionmetalandheavymetalions[1,2 ] ,therearemanyreportsofthecomplexesinhost guestchemistry ,molecularrecognition[3 ,4] andionophoreinmembranetransportation[5] ,butthereislittlereportontheirrareearthscomplexesandthefluorescenceaboutthecomplexes[6] ,andthefluorescenceintensityoftheircomplexesarenotverystrong .Weinsetbenzoylgroupintothemacrocycle ,expectingthatitsrareearthscomplexeshavebetterfluorescenceproperties .Inthispaperthesynthesis…     

Synthesis, Characterization of α-Oxopentanedioic Acid-Isonicotinoyl Hydrazone Rare Earth-Complexes and Relaxivity of Gd-complex

Themagneticresonanceimaging (MRI)tech niqueforthemedicineisveryusefultodiagnosepre tumorandbloodvesseldiseaseinheartandbrainandothermalignantpre diseases .Therefore ,specialatten tionhasbeenalsopaidtoMRIcontrastagents ,whichareindispensablediagnosingdrugsforthemagneticresonanceimagingtechnique[1,2 ] .Gadolinium (Ⅲ)complexwithsomepolycarboxylicandpolyaminelig ands ,suchasGd(DTPA)·nH2 O ,waswidelyusedincliniclongago .OurpreviousworkshowsthatsomepolycarboxylicSchiffbasecomplexeswithrareea…     

Synthesis, characterization and properties of some rare earth complexes with 2,6-pyridine dicarboxylic acid and α-Picolinic acid

Five novel ternary complexes were synthesized by the rare earth with 2,6-pyridine dicarboxylic acid andα-picolinic acid.These complexes were characterized by elemental analysis,molar conductivity,FT-IR,UV-Vis,Raman,TG-DTA and XRD.The general formula of the complexes was[RE(DPA)(L α )(H2O)]·2H2O(RE=Pr 3+ ,Nd 3+ ,Sm 3+ ,Eu,Er 3+ ;DPA=2,6-pyridine dicarboxylic acid;L α =α-picolinic acid). The investigation of fluorescence properties of the Eu-complex showed that the Eu(III)ion could be sensitized efficiently by the ligand to some extent.The antibacterial activity test indicated that all the five complexes exhibited antibacterial ability against Escherichia coli and Staphylococcus aureus with broad antimicrobial spectrums.     

Synthesis, Catalysis of Rare Earth Complexes with Aliphatic Noncyclic Polyether-Amino Acid Schiff Base

Coordination chemistry of rare earth with Schiffbase has developed rapidly in the last fewyears ,butthe majority of the complexes studied are derivedfromaromatic Schiff base .So far less papers of rare earthcomplex with aliphatic Schiff base have been rep…     

Anti-diabetic drugs as a cause of hypoglycaemia among acute medical admissions in Hong Kong and Singapore--relationship to the prescribing patterns in diabetic patients

By a reaction of salicylaldehyde (Scl) with the corresponding amino acids and by the next complexation reaction of the formed Schiff bases with Cu2+ ions in an aqueous-alcoholic medium, aqua (N-salicylideneaminoalkanoato)copper(II) complex chelates of the composition Cu(Scl-DL-Asp(2-)) (H2O)2, Ip and Cu(Scl-L-Asn(2-)(H2O), In were prepared. The monodiazole complexes with pyrazole IIp and IIn (as monohydrate) as well as with 3,5-dimethylpyrazole IIIp a IIIn were prepared by replacing the molecule of H2O in the parent aquacomplexes with the diazoles under the same reaction conditions. Using a routine dilution micromethod, the antimicrobial activity of the prepared complexes and free diazoles was tested against Staphylococcus aureus, Escherichia coli and Candida albicans. Only a significant antistaphylococcus activity was found (highest for the complex IIn; MIC = 39 micrograms/cm3). All chelates (Ip,n-IIIp,n) were more effective (MIC = 39-156 micrograms/cm3) than both pyrazole (312 micrograms/cm3)and 3,5-dimethylpyrazole (625 micrograms/cm3) alone. The relationship between the coordination-chemical properties and the biological effects of the complexes studied is discussed.     

Syntheses, Crystal Structures and Kinetic Mechanisms of Thermal Decomposition of Rare Earth Complexes with Schiff Base Derived from o-Vanillin and p-Toluidine

Withtheincreasingapplicationofrareearthmet alsinavarietyoffields,rareearthionscontinuallyin trudeintogeneralenvironmentandfurtherintothe bodiesofplants,animalsandhumanbeings.Itis thereforeofsignificancetoinvestigatethephysiological actionandlong termeffectofrareearthiononbiologi calbodies.VariousstudieshaveshownthatSchiff basesderivedfromsalicylaldehydeanditsderivatives haveconsiderablebiologicalimportancepartlybecause suchligandshavemanydonoratoms(N,O)andare analogoustobiologicalenvironmentt…     

Synthesis, fluorescence properties of Eu(Ⅲ) complexes with novel carbazolefunctionalized β-diketone ligand

A novel carbazole functionalized β-diketone, methyl 6-(9-ethylcarbazole-3-yl)-oxoacetyl-2-pyridinecarboxylate (MEP), and its Corresponding Corresponding binary Eu(Ⅲ) complexes Eu(MEP)32H2O and ternary complex Eu(MEP)3Phen with 1,10-Phenanthroline (Phen) were pre-pared. The ligand was characterized based on elemental analysis, FT-IR, and 1H NMR, and the complexes were characterized with elemental analysis, FT-IR and thermogravimetric and differential thermal analysis (TG-DTA). The investigation of fluorescence properties of the com-plexes Eu(MEP)32H2O and Eu(MEP)3Phen showed that the Eu(Ⅲ) ion could be sensitized efficiently by the ligand to some extent, in par-titular, in the ternary system, the secondary ligand Phen acting as a light-harvesting center was involved in the highly efficient energy transfer process, and the emission was stronger than the binary complex. In addition, the introduction of the carbazole moiety enlarged the π-conjugated system of the ligand and enhanced the luminescent intensity of the complexes.     

Adduct formation between alkali metal ions and anionic LV(V)O(2)(-) (L(2-) = tridentate ONS ligands) species: syntheses, structural investigation, and photochemical studies

Syntheses of alkali metal adducts [LVO(2)M(H(2)O)(n)] (1-7) (M = Na(+), K(+), Rb(+), and Cs(+); L = L(1)(-)L(3)) of anionic cis-dioxovanadium(V) species (LVO(2)(-)) of tridentate dithiocarbazate-based Schiff base ligands H(2)L (S-methyl-3-((5-(R-2-hydroxyphenyl))methyl)dithiocarbazate, R = H, L = L(1); R = NO(2), L = L(2); R = Br, L = L(3)) have been reported. The LVO(2)(-) moieties here behave like an analogue of carboxylate group and have displayed interesting variations in their binding pattern with the change in size of the alkali metal ions as revealed in the solid state from the X-ray crystallographic analysis of 1, 3, 6, and 7. The compounds have extended chain structures, forming ion channels, and are stabilized by strong Coulombic and hydrogen-bonded interactions. The number of coordinated water molecules in [LVO(2)M(H(2)O)(n)] decreases as the charge density on the alkali metal ion decreases (n = 3.5 for Na(+) and 1 for K(+) and Rb(+), while, for Cs(+), no coordinated water molecule is present). In solution, compounds 1-7 are stable in water and methanol, while in aprotic solvents of higher donor strengths, viz. CH(3)CN, DMF and DMSO, they undergo photoinduced reduction when exposed to visible light, yielding green solutions from their initial yellow color. The putative product is a mixed-oxidation (mu-oxo)divanadium(IV/V) species as revealed from EPR, electronic spectroscopy, dynamic (1)H NMR, and redox studies.     

Synergistic extraction of rare earths by mixture of HDEHP and HEH/EHP in sulfuric acid medium

The extraction of RE（Ⅲ） （RE=La, Nd, Sm, Gd） in sulfuric acid medium using the mixture of HDEHP（H2B2） and HEH/EHP（H2L2） was investigated. The synergistic enhancement coefficient（R） was calculated for La （1.96）, Nd（3.52）, Sm（5.96）, and Gd（5.71）, respectively, at pH=2.0, and it was seen that the R increased with the increase of aqueous quilibrium pH. The configuration of the extracted complexes was considered to be RE（SOa）xH2x（HB2）3 with HDEHP, RE（SOa）xH2x（HL2）3 with HEH/EHP, and RE（HB2）2（HL2） with their mixture as the extractant with the slope method. The equilibrium constants and stability constants were calculated. A cation exchange mechanism was proposed as well.     

Synthesis, Characterization and Bioactivity of Complexes of Rare Earth with Bis-Schiff Base from Furoylpyrazolone

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