共查询到19条相似文献,搜索用时 218 毫秒
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目的:“药食同源”类食品产业发展前景广阔,为推进产业持续健康发展提出相应的对策与建议。方法:基于整理现有文献、政策法规及公开数据等,探讨“药食同源”的起源及内涵,梳理中药材产业和“药食同源”类食品产业发展现状,指出“药食同源”类食品产业存在的问题。结果:目前,我国“药食同源”类食品产业政策方向明确,国内外关注度持续提高,发展势头强劲,成为增长主力,“药食同源”类中药材进出口强势;但存在研发投入不足、“药食同源”类食品品牌价值低、受国外“药食同源”类食品企业威胁、产业标准化程度低等问题。结论:建议以创新为动力,引领“药食同源”产业发展;树立品牌意识,打造品牌效应;发挥自身优势,开拓国外市场;加强融合发展,促进增值增效。 相似文献
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随着医学的不断发展和人们健康意识的提高,药食同源食品受到越来越多的关注。同一种食材含有多种活性成分,如多酚类、多糖类以及植物纤维等,因此不仅可以在日常饮食中起到保健的作用,也可以运用到药物中达到治疗和防治疾病的效果。本文对药食同源相关概念进行简单阐述,并梳理了多种药食同源食材的研究进展及其在保健品和药品上的应用价值,为“健康中国”战略背景下药食同源食材的研究、生产和应用提供参考。 相似文献
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食药同源理念在我国有上千年的发展历史,现代研究发现从食药同源植物里提取的多糖成分能够影响肠道免疫和肠道微生态组成,从而发挥调控肠道稳态并改善机体病症的作用。随着植物多糖活性研究的深入,食药同源植物多糖的生物活性及其作用机制得到越来越多的关注,根据理论研究利用食药同源植物多糖研发出有益于人体健康的食品及医药产品具有广阔前景。本文基于机体中肠道免疫与肠道菌群的关系,重点分析了食药同源植物多糖可通过保护肠道黏膜、抑制肠道内炎症因子、维持肠道菌群平衡、改善肠道菌群代谢产物,发挥修复肠道黏膜、改善肠道炎症、预防肠道肿瘤等多种作用;论述了食药同源植物多糖研究现状的不足之处;展望了食药同源植物多糖在食品行业、医药行业的应用前景,以期为该类多糖的研究和利用提供参考。 相似文献
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目的:了解长沙某地居民对药食同源中药材认知、态度以及使用情况。方法:使用分层整群随机抽样的方法随机调查长沙某地区居民800名,调查其认知、态度、行为层面共9项问题,分析其对药食同源中药材的知信行现状。结果:长沙某地居民对药食同源中药材知识的熟悉程度相对较低;学习中医饮食调理方法、尝试使用药食同源中药材、主动通过多途径获取相关知识的意愿度较低;较多将药食同源中药材用于慢性病治疗和疾病预防,少部分将其用于美容减肥。结论:要加强药食同源理论建设,完善理论体系,有针对性地进行科普以提升居民的药食同源中药材相关知识水平,从认知层面改变居民态度和使用方式。 相似文献
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“食药同源”文化作为中国传统医药文化的重要组成部分,在国际上具有重要的地位和影响力。根植于中华民族的千年智慧和医学传统,“食药同源”文化将食物和药物视为共同的源泉,推崇“食疗”理念,而“食药同源”产业的兴起则是对这一文化传统的现代演绎和传承。本文回顾中国悠久的“食药同源”文化历史,并探讨其在传统医药领域中的重要地位和影响力。通过综合文献调研和数据可视化分析,系统梳理当前“食药同源”食品产业的现状。最后,总结并展望“食药同源”食品产业面临的挑战以及未来发展趋势,旨在为我国“食药同源”食品研发及产业发展提供思路和借鉴。 相似文献
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Overexpression of P-glycoprotein (P-gp) and multidrug resistance-associate protein 1 (MRP1) is a major mechanism leading to multidrug resistance (MDR) of cancer cells. These transporters expel anti-cancer drugs and greatly impair therapeutic efficacy of chemotherapy. A Chinese herbal plant Yanhusuo (Corydalis yanhusuo W.T. Wang, YHS) is frequently used in functional food and traditional Chinese medicine to improve the efficacy of chemotherapy. The objective of this work was to study effects of glaucine, an alkaloid component of YHS, on P-gp and MRP1 in resistant cancer cells.The resistant cancer cell line, MCF-7/ADR and corresponding parental sensitive cells were employed to determine reversal properties of glaucine. Glaucine inhibits P-gp and MRP1-mediated efflux and activates ATPase activities of the transporters, indicating that it is a substrate and inhibits P-gp and MRP1 competitively. Furthermore, glaucine suppresses expression of ABC transporter genes. It reverses the resistance of MCF-7/ADR to adriamycin and mitoxantrone effectively. 相似文献
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多重耐药(multidrug-resistant,MDR)革兰氏阴性病原菌感染面临无药可用的局面,正日益成为全球性公共卫生危害。畜禽被认为是耐药病原菌的重要携带者,是动物源食品中多重耐药菌传播的源头之一。MDR病原菌可以通过“养殖场-屠宰场-加工厂-市场”这一链条传播给人类,对人类健康造成严重危害。MDR菌株的高流行率以及耐药基因在不同细菌种属之间的传播,使得多重耐药特征在不同细菌间快速扩散。新型耐药基因接合质粒、辅助接合质粒加速了食源性细菌中耐药基因的水平转移,进而加剧MDR病原菌对人类健康的威胁。本文通过综述常见造成动物源食品污染的革兰氏阴性菌的分子流行特征和耐药机制,以期为预防和控制食源性耐药病原菌提供一定理论依据。。 相似文献
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中药发酵技术历史悠久,是中药炮制的一种重要方法。随着全民健康意识的提高,人们将益生菌广泛应用于药食两用中药,利用益生菌发酵中药成为科学研究的热点,通过中药发酵技术开发出的一系列健康产品颇受消费者的青睐,拥有广阔的市场前景。中药经益生菌发酵后具有提高药效、更易人体吸收、降低毒副作用等优势,该文从单一菌种发酵中药和多菌种混合发酵中药两方面对益生菌发酵中药的研究现状进行阐述,并对益生菌发酵药食两用中药开发的相关产品进行综述,为该领域进一步深入研究探索及相关开发提供参考。 相似文献
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The spread of antibiotic resistance via meat poses a serious public health concerns. During 2007-2009, a total of 586 retail meat samples (318 pork and 268 chicken meats) were collected from three provinces (Bac Ninh, Ha Noi and Ha Tay) of North Vietnam to determine the prevalence of Salmonella. Isolates were characterized by serotyping and antibiotic susceptibility testing. Approximately 39.6% (n=126) of pork and 42.9% (n=115) of chicken samples were Salmonella-positive, and 14 Salmonella serovars were identified. Anatum (15.8%) was the most common serovar, followed by Infantis (13.3%), Emek (10.4%), Derby and Rissen (9.5%), Typhimurium (9.1%), Reading (7.5%) and London (6.2%). The isolation frequency of serovars Enteritidis, Albany, Hadar, Weltevreden, Newport and Blockey ranged from 1.2%-5.8%. Resistance to at least one antibiotic agent was detected in 78.4% of isolates (n=189) and the most frequent resistance were to tetracycline (58.5%), sulphonamides (58.1%), streptomycin (47.3%), ampicillin (39.8%), chloramphenicol (37.3%), trimethoprim (34.0%) and nalidixic acid (27.8%). No Salmonella isolates were resistant to ceftazidime. Chicken isolates had higher resistance to antibiotic agents than pork isolates (P<0.05). It showed that 159 Salmonella isolates belong to the 14 serovars were multidrug resistant (MDR) and 50 MDR patterns were found. This study indicated that Salmonella serovars isolated from retail meat samples were resistant to multiple antibiotics and this resistance was widespread among different serovars. The widespread resistance may have arisen from misuse or overuse of antibiotics during animal husbandry in North Vietnam. 相似文献
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Human hepatic cancer cells, HepG2, formed spheroids on a poly-L-glutamic acid-coated dish. Doxorubicin (DOX) efflux activity of the cells in spheroid culture was higher than that in monolayer culture due to the higher expression of MDR1 protein of the cells in spheroids compared with those in monolayer. The amount of MDR1 per cell in spheroids was similar to that of hepatic tumor tissue in vivo. Consequently, it was suggested that the drug efflux activity of cells in spheroid culture reflected the activity of hepatic cancer cells. Furthermore, the IC(50) of DOX and epirubicin (EPI) in HepG2 cells, both of which are known to be exported by MDR1, were higher in spheroid compared with monolayer cells, while IC(50) of 5-fluorouracil (5-FU), which is not exported by MDR1 protein, was almost the same in both types of culture. The higher IC(50) of DOX and EPI in HepG2 cells in spheroid culture was associated with a higher efflux activity of the drugs in the spheroid-cultured cells, which appeared to reflect the IC(50) of DOX and EPI in cancer cells in vivo. Therefore, a spheroid culture of hepatic cancer cells seems to provide a promising cell-based in vitro assay system for examining the proper IC(50) values of anticancer agents that would reflect the drug resistance of cancer cells in vivo. In addition, the system would be useful in screening for inhibitors of MDR1 activity, which will help to overcome the multidrug resistance of cancer cells. 相似文献
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葛根为我国传统的药食两用植物,葛根素为其主要药效成分之一。依据中医药理论,葛根具有解表退热、生津止渴的功效。现代药理学研究表明,葛根及葛根素均具有显著的脑保护活性,对阿尔茨海默病、帕金森病及脑卒中等模型动物或细胞产生保护作用,其机制与调节GSK-3β/Nrf2、PI3K/Akt、cAMP/PKA等神经细胞凋亡信号转导通路有关。提示葛根具备开发为抗神经系统疾病保健食品的潜在价值。 相似文献