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On examination of the thumbs of 20 dissected preparations of ligaments and joints, of ten dry skeletons and of a number of living hands, apoposition (from apo = away from) was distinguished as a position in which the first carpometacarpal joint is fully abducted and laterally rotated and in which one or both distal joints of the thumb are flexed. Apoposition is commonly used in writing and it has a specific osteoligamentous basis for its stability: (1) a Y-shaped intermetacarpal ligament is attached by two crura to the base of the second metacarpal bone and by a common stem to the first metacarpal. Together with the palmar and dorsal oblique ligaments it becomes taut at abduction and establishes thereby a fixed center for the circumduction. Stability is enhanced as the circumduction takes place in the radial flat part of the joint away from the center; (2) of the two palmar prominences of the head of the first metacarpal bone the radial is the larger. At 25-30 degrees flexion in the metacarpophalangeal joint the prominence fits into an excavation on the base of the proximal phalanx in a manner which together with the ulnar collateral ligament locks the joint against mutual abduction and lateral rotation, and (3) the radial part of the trochlea of the interphalangeal joint is larger than the ulnar and secures, together with the ulnar collateral ligament, the joint against a radial luxation. Apoposition does not require activity of the thumb muscles; it is brought about by applying an external force to the ulnar side of the thumb and it is checked by ligaments and the shape of the joints.  相似文献   

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Nonmalignant respiratory disease (NMRD) mortality was examined among woodworkers participating in the American Cancer Society's CPS-II cohort study. During the 6-year prospective follow-up there were 97 NMRD death's among 11,541 men reporting employment in wood-related occupations and 1,338 NMRD deaths among 317,424 men reporting no exposure to wood dust or wood-related jobs. Relative risks, adjusted for age and smoking, were calculated using Poisson regression. A small excess of NMRD was observed among woodworkers. However, the relative risk was higher among woodworkers who did not report exposure to wood dust (RR = 1.52, 95% CI = 1.18-1.97) than those who did (RR = 1.27, 95% CI = 0.91-1.77), and no clear trend with duration of exposure was observed. An excess of NMRD was observed among woodworkers reporting exposure to asbestos (RR = 1.59, 95% CI = 0.85-2.96), as well as the small number of woodworkers reporting exposure to formaldehyde (RR = 1.95, 95% CI = 0.63-6.06), but men not reporting exposure to these substances also had an excess risk. Although limited by a short follow-up period and crude indicators of exposure, the strengths of this analysis were the ability to compare woodworkers to a similar, healthy population and to adjust for the effects of smoking. Cohort studies with better exposure information are needed to examine the role of occupational exposures among woodworkers in the etiology of respiratory disease.  相似文献   

4.
对包钢热电厂除氧器除氧效果不好的现象进行认真分析后,总结出一套提高除氧效果的技术方法.  相似文献   

5.
At least one study has questioned the safety of electroconvulsive therapy (ECT) in the very old. In this study, the authors reviewed a 5-year experience with ECT at two university psychiatric services for patients 75 years of age or older. Both outcomes and complications were reviewed. Nineteen of 22 patients (86.3%) were ECT responders. Five patients (22.7%) suffered complications which varied from minor to substantial. ECT was found to be an effective and reasonably safe treatment for depression in the very old.  相似文献   

6.
Signals generated by T cell receptor (TCR) cross-linking (or phorbol 12-myristate-13-acetate + Ca2+ ionophore), glucocorticoids or ionizing radiation all stimulate apoptotic cell death in thymocytes by signals that are initially distinct from each other. However, when these stimuli were administered to thymocyte cultures that were maintained under an atmosphere containing less than 20 ppm oxygen as opposed to one that contained 18.5% molecular oxygen, cell death was inhibited or abrogated, suggesting that the induction of death by all three different stimuli depend on the presence of molecular oxygen. Studies of the effects of the cysteine analog N-acetyl cysteine (NAC) with normal thymocytes demonstrated that this antioxidant inhibited the induction of death by each of the different stimuli in a manner the paralleled anaerobiosis. Furthermore, studies with thymocytes demonstrated that the induction of nur77, a gene shown to be involved in thymocyte apoptosis signaled through the TCR or its surrogates, is not inhibited by NAC or dependent upon molecular oxygen. The possible implications for negative selection of NAC-mediated inhibition of TCR-signaled thymocyte cell death was examined in thymic organ culture. Treatment of these cultures with NAC provided significant protection against staphylococcal enterotoxin B-mediated deletion of V beta 8-expressing thymocytes.  相似文献   

7.
The use or abuse of many preparations, available in the gymnasium or as top-bench drugs, used as nutritive integrators, determines both toxicological and deontological and especially sport medicine problems, because these products are also involved in the antidoping control. Therefore, this article cover the needs for providing a consultation and information manual for all sport operators in the delicate phase of drug-food integration of the athlete, not only to prevent and restrict the doping phenomenon, but also for health-preservation of the athlete.  相似文献   

8.
OBJECTIVE: To evaluate the efficiency of respiratory muscle training programs in pilots. METHODS: Twenty-four male pilots were divided into two groups. The training group (12 pilots) underwent respiratory strengthening training programs besides routine physical exercises. The other 12 pilots in the control group only did routine physical exercises, but the training time was the same in these two groups. Before and after training programs in the two groups, the respiratory muscle functions were examined. RESULTS: 24 pilots in these two groups completed training programs within four weeks. The pilots in the training group got improvement of respiratory muscle functions which was much better than those of the control group. CONCLUSION: It suggests that the strengthening training programs of respiratory muscles can improve and strengthen the respiratory muscle functions in pilots.  相似文献   

9.
The committee "would attempt to produce a scholarly psychologist well grounded in scientific method, theory, knowledge, and critique, as these pertain to the pursuit of a career in either scientific or applied psychology." They believe that "psychology can serve society best by reducing the amount of specialization at the predoctoral level and by training the PhD… . A psychologist so trained will be able to adapt to the changing situation in a dynamic society." Major sections are: Implications for Psychology, Articulation of Nondoctoral and Doctoral Graduate Programs, and Recommendations. The APA Education and Training Board should have an annual article in the "American Psychologist" providing pertinent information on graduate training programs, graduate selection standards, and philosophy of graduate training. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

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Reactive oxygen species (ROS) are probably not only unintended, toxic side-products of oxygen metabolism in mammalian cells, they also have several important physiologic functions including antimicrobial killing, regulation of cellular proliferation and growth, and regulation of vascular tone. ROS are generated within the vessel wall by several mechanisms, including a vascular type of a NAD(P)H oxidase. ROS formation can be stimulated by mechanical stress, environmental factors, the peptide angiotensin II, cytokines, native low-density lipoproteins (LDL), and in the presence of catalytic metal ions. Their ability to modify LDL, react with endothelial-derived nitric oxide subsequently forming peroxynitrite, and amplify the expression of various genes important for leukocyte recruitment within the arterial wall are the basis of the oxidant injury theory of atherosclerosis. In animal studies, antioxidant therapy (probucol, butylated hydroxytoluene, N', N'-diphenylenediamide, vitamin E, superoxide dismutase) have been successfully used to prevent fatty streak formation, and to restore impaired nitric oxide-dependent vasorelaxation. In man, antioxidant therapy (e.g., supplementation with vitamin E) clearly increased the resistance of LDL to oxidative modification. Case-controlled and prospective clinical studies suggest a relation between baseline antioxidant plasma levels and/or antioxidant supplementation and risk of cardiovascular events. In one secondary prevention trial (randomized, blinded, placebo-controlled), vitamin E supplementation reduced significantly the risk for non-fatal myocardial infarctions. Before general recommendations can be made, results of further large-scale trials should be awaited.  相似文献   

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《Hydrometallurgy》2007,85(2-4):193-202
The role of oxygen in thiosulphate leaching of gold has been investigated in both pure gold and ore systems. The gold dissolution decreased in the presence of oxygen in the pure gold system. Air or oxygen bubbling caused higher consumption of thiosulphate and leaching passivation. Nitrogen bubbling largely increased gold dissolution and this beneficial effect appeared to be more noticeable at a higher nitrogen flowrate. Nitrogen bubbling stabilised thiosulphate and prevented the passivation of gold. The use of oxygen pre-saturated water had little effect on gold dissolution. The counter current leaching tests showed that both gold passivation and the products due to thiosulphate decomposition affected the gold dissolution. The leaching solutions could be re-used without any impact on gold dissolution under a nitrogen atmosphere.Mineralogy affected the thiosulphate leaching system under different atmospheres. The leaching behaviour of a sulphide ore with only a small amount of sulphides was determined by the leaching behaviour of gold. However, air bubbling gave a higher overall recovery in the leaching of a pyrite concentrate, while nitrogen bubbling only marginally increased the overall gold recovery. Oxygen injection enhanced the dissolution of sulphides, releasing more gold from the sulphide matrices. Nitrogen injection hindered the corrosion process of the sulphides, affecting the overall gold recovery. Nitrogen bubbling decreased the thiosulphate consumption in the leaching of the pyrite concentrate, while air bubbling increased the thiosulphate consumption. It is suggested that high sulphide containing ores should be pre-treated to fully or partially break down the sulphide matrices to liberate gold, followed by gold leaching under a nitrogen atmosphere.  相似文献   

14.
The role of psychology department clinics in the development of the discipline of clinical psychology is discussed, and an ideological and structural framework for enabling such clinics to facilitate the integration of research and practice is provided. The University of Massachusetts Psychological Services Center is described as an example of a clinic operating within this framework. Several examples of clinical scholarship that have evolved in this setting are offered. Some of the key characteristics of a training clinic subscribing to the objective of training clinical psychologists with scientist-professional ideals and capabilities are reviewed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

15.
The role of oxygen free radicals in isoniazid-induced hepatotoxicity   总被引:1,自引:0,他引:1  
This report describes the glycosaminoglycans, collagen and elastin--composition of leiomyosarcoma. Studies were performed on leiomyosarcoma removed during surgery. The material was taken from 7 patients. Rearrangement of extracellular matrix in leiomyosarcoma has been found. There was an increase of total collagen content in comparison to control uterus. In both tissues type I collagen was found to be the predominant one. Both tissues, normal and neoplastic contain all known glycosaminoglycans types. Among them heparan sulphate was found to be the most abundant. A slight decrease in the content of this glycosaminoglycan was observed in leiomyosarcoma. A possible role of these alterations in tumour biology is discussed.  相似文献   

16.
Investigated all links of oxygen homeostasis of patients in early period afterwards surgical stoppage gastro-intestinal bleeding and urgent intravascular volume replacement. Macrodelivery of oxygen (DO2) was reduced in two and more time in comparison with norm predominant in connection with anemia. In spite of the infringement of transport of oxygen through alveolar-capillary membrane (especially in patients with complications and death in early postoperative period), little affected of degree of hemoglobin saturation by oxygen. Despite decrease of erythrocyte zeta-potential, largely expressed in cases of lethal outcome, considerable infringement of passage through microcirculation vessels is fixed was not. The increase of degree of morbidity and anaerobic metabolism in early postoperative period was accompanied of hyperdynamic hemodynamic reaction. The increase of degree of morbidity was accompanied of increase oxygen deficit owing to infringement of oxidoreduction in fabries also.  相似文献   

17.
The spread of brucella infection under modern conditions of cattle breeding were studied with the foci in the Rostov region taken as an example. The main epidemiological features and tendencies of epidemiological importance were established. To find out specific antigen in different environmental objects, the approbation of the enzyme immunoassay test systems was carried out and the possibility of their use at the institutions of the State Sanitary and Epidemiological inspection was shown.  相似文献   

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Examined the relative contributions of admissions interview ratings and various objective measures, such as GPA and test scores, in discriminating among 60 applicants to a clinical psychology program either accepted for admission, placed on an alternate list, or denied admission. Results show that interview ratings, particularly ratings of the applicant's clinical potential, contributed incrementally to group separation when first taking into account the contributions of the objective measures. The need to validate interview evaluations as a basis for selection decisions and to examine utilization of admissions criteria is discussed. (16 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

20.
The number of Hungarian dentists around the second millennium is analysed. Keeping the actual number of student's intake, the number of dentists will decrease significantly between 2002 and 2015. Therefore, the consideration of this possible critical situation is urgent.  相似文献   

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