共查询到1条相似文献,搜索用时 0 毫秒
1.
This study examines the effect of diacylglycerol (DAG) oil consisting mainly of 1,3-species on fat oxidation as a possible
mechanism for anti-obesity. We examined the following: (1) the long-term (23-week) effects of a DAG oil diet on the development
of obesity; (2) the effect of a single ingestion of DAG oil on fat oxidation; and, (3) the short-term (2-week) effect of a
DAG oil diet on fat metabolism in rats. Rats fed a DAG oil diet accumulated significantly less body fat compared to rats fed
a triacylglycerol (TAG) oil diet, each oil possesses a similar fatty acid composition. More 14C-CO2 was expired and less 14C-radioactivity was incorporated into visceral fat after administration of a tracer emulsion containing 1,3-[oleoyl-1-14C] diolein compared to [carboxyl-14C] triolein. Indirect calorimetry showed respiratory quotients were significantly lower in the DAG oil diet group than in
the TAG oil diet group. More 14C-CO2 was expired and less 14C-radioactivity was incorporated into visceral fat in the DAG oil diet group than in the TAG oil diet group after a single
intragastric administration of [carboxyl-14C] triolein. These results suggest the following. (1) DAG oil has an inhibitory effect on diet-induced fat accumulation. (2)
1,3-DAG, a major component of DAG oil, is more susceptible to oxidation. (3) A short-term ingestion of DAG oil increases fat
utilization at the whole body level and results in increased oxidation of dietary fat. The stimulated fat oxidation might
be one explanation for the anti-obesity effect of long-term DAG oil ingestion. 相似文献