妈咪爱联合蒙脱石散治疗小儿腹泻的临床疗效观察

目的:观察妈咪爱联合蒙脱石散治疗小儿腹泻的临床疗效.方法:90例小儿腹泻患儿随机分成观察组和对照组两组各45例,对照组采取常规治疗,观察组在常规治疗的基础上加用妈咪爱联合蒙脱石散治疗,比较两组的疗效.结果:妈咪爱联合蒙脱石散治疗小儿腹泻的总有效率为91.15%,而采用常规治疗的对照组的总有效率为77.8%,观察组总有效率明显高于对照组(P<0.05).且观察组的大便好转时间、止泻时间、退热时间均明显短于对照组(P<0.05).结论:妈咪爱联合蒙脱石散治疗小儿腹泻疗效确切,可以明显改善患儿的临床症状,缩短腹泻治疗的时间,值得临床推广和应用.     

消旋卡多曲治疗婴幼儿腹泻88例疗效观察

目的 观察消旋卡多曲颗粒治疗婴幼儿腹泻的疗效.结果 将88例腹泻患儿随机分为治疗组和对照组.两组均采用常规综合治疗,治疗组在对照组基础上加用消旋卡多曲颗粒口服,比较两组疗效.结果治疗组和对照组总有效率分别为80.0%和55.8%,两组比较有显著性差异(P<0.05).结论 在常规治疗基础上加用消旋卡多曲颗粒治疗婴幼儿腹泻可较快缓解病情,值得临床推广使用.     

无创通气联合支气管肺泡灌洗对COPD合并肺部感染和Ⅱ型呼吸衰竭患者的疗效

目的:探讨无创通气联合支气管肺泡灌洗对COPD合并肺部感染和Ⅱ型呼吸衰竭患者的疗效.方法:50例不需立即有创机械通气治疗的COPD合并肺部感染和Ⅱ型呼吸衰竭患者,随机分为对照组26例和灌洗组24例.对照组行常规治疗及无创正压通气(NIPPV);灌洗组在对照组治疗基础上行支气管肺泡灌洗(BAL).观察两组在治疗前后各项指标变化及疗效.结果:血气分析同组内治疗前后比较差异有统计学意义(P<0.01),两组间比较差异有显著性(P<0.01);第4天灌洗组WBC、中性粒细胞率、CRP水平较对照组明显降低(P<0.01);灌洗组细菌培养阳性率及观察第7天X线示胸片炎性病变吸收率均明显高于对照组(P<0.01);灌洗组有创通气上机率、住院时间明显低于对照组(P<0.05),治愈率明显高于对照组(P<0.05),两组病死率差异无统计学意义(P＞0.05),两组均无严重并发症.结论:对不需立即行持续有创通气治疗的COPD合并肺部感染和Ⅱ型呼吸衰竭患者,无创通气联合BAL治疗较安全,临床疗效确切,值得临床推广应用.     

慢性胃溃疡的治疗

目的:观察中西医结合治疗胃溃疡的临床疗效.方法:将本院200例胃溃疡患者随机分为治疗组及对照组,对照组采用西医疗法,治疗组在对照组基础上加服中药方剂.结果:治疗组的总有效率明显高于对照组;而且远期疗效亦好,复发率亦明显降低,差异有统计学意义(P<0.05);两组均无明显不良反应.结论:中西医治疗胃溃疡疗效优于纯西药治疗,且副作用少,价廉方便,值得推广使用.     

中药配合手法治疗椎动脉型颈椎病50例

目的:观察中药配合手法治疗椎动脉型颈椎病的临床疗效.方法:将80例患者随机分为2组,治疗组50例给予中药配合手法治疗;对照组30例以颈椎牵引治疗.结果:总有效率治疗组为86.0%,对照组为56.7%,2组比较,差异有非常显著性意义(P<0.01).结论:中药配合手法治疗椎动脉型颈椎病疗效优于颈椎牵引治疗.     

中西医结合治疗腹泻型肠易激综合征41例

目的:观察中医药联合双歧杆菌三联活菌胶囊治疗腹泻型肠易激综合征(IBS)的疗效,方法:将43例腹泻型IBS患者随机分为2组,治疗组23例,给予中药柴胡疏肝散配合口服双歧杆菌三联活菌胶囊,每日3次;对照组20例,给予口服双歧杆菌三联活菌胶囊,每日3次.结果:治疗4周后,治疗组总有效率95%,对组照75%,两组有比较差异有统计学意义(P＜0.01).结论:中西医联合应用治疗腹泻型IBS有较好的疗效.     

强肾片合雷公腾多甙治疗系膜增生性肾小球肾炎的临床观察

目的:观察强肾片合雷公腾多甙治疗系膜增生性肾小球肾炎的临床疗效.方法:将60例患者随机分为治疗组和对照组,对照组予雷公腾多甙口服,治疗组在对照组的基础上加用强肾片.疗程共8周.结果:治疗组治疗后的疾病疗效和证候疗效与对照组比较,差异均有显著性意义(P<0.05).治疗组治疗后的24小时尿蛋白、血肌酐、血尿素氮和血清胱抑素C与本组治疗前比较,差异均有非常显著性意义(P<0.01),与对照组治疗后比较,差异亦均有显著性意义(P<0.05).对照组治疗后各项实验室指标与治疗前比较,差异均有显著性意义(P<0.05).结论:强肾片合雷公腾多甙治疗系膜增生性肾小球肾炎优于单用雷公腾多甙.     

腰椎间盘突出症的中西医治疗技术探析

目的:探讨中西医结合治疗腰椎间盘突出症的临床疗效.方法:选取我院2007年1月至2009年12月确诊为腰椎间盘突出症患者128例.分为两组观察,其中观察组64例(中西医结合治疗组),并选取同期单纯西医治疗病例64例为对照组,对比分析两组的临床疗效.观察8周.结果:观察组临床症状改善及治愈率较对照组高,临床各种症状及愈后恢复情况观察组均好于对照组.观察组总有效率明显高于对照组,两组差异性有统计学意义(P<0.01).结论:中西医结合治疗腰椎间盘突出症可明显改善临床症状,疗效确切,安全可靠,具有较好的临床价值.     

中西医结合治疗类风湿性关节炎的疗效观察

目的:探讨中西医结合方法治疗类风湿性关节炎(RA)的临床疗效.方法:将我院2009年6月至2010年12月间收治的150例类风湿性关节炎患者随机分为对照组(单纯西药治疗:布洛芬缓释胶囊+甲氨蝶呤片)和治疗组(西药治疗基础上联合中药治疗),每组各75例.每组患者均以4周为一个疗程,治疗24周后比较两组疗效.结果:治疗组和对照组有效率分别为89.3%和76.0%,比较差异有统计学意义(P<0.05);治疗组患者在改善主要症状与体征方面优于对照组,差异有统计学意义(P<0.05).结论:中西医结合方法治疗类风湿性关节炎临床效果显著.     

三联疗法治疗复发性生殖器疱疹

目的:评价长程三联疗法治疗频繁复发性生殖器疱疹的疗效.方法:口服阿昔洛韦、肌注干扰素同时微波治疗,治疗组连用3个月,对照组连用10天,进行对照观察,并对所有患者治疗后1年内进行追踪随访.结果:治疗10天两组病人临床疗效比较差异无显著性(P>0.05).治疗后观察1年内复发次数,治疗组明显低于对照组,疗效差异有非常显著性(P<0.01).结论:三联疗法对控制频繁复发性生殖器疱疹的复发率有显著效果     

Voices of fear and anxiety and sadness and depression: The effects of speech rate and loudness on fear and anxiety and sadness and depression.

Two studies investigated the role of expressive vocal behavior (specifically, speech rate and loudness) in fear and anxiety and in sadness and depression. In the 1st study, participants spoke about personally experienced fear and anxiety-arousing and neutral events using 3 different voice styles: fast and loud, normal, and slow and soft. In the 2nd study, participants spoke about personally experienced sad or depressing and neutral events using the same 3 voice styles. In both studies, the participants' highest levels of subjective affective and cardiovascular (CV) arousal occurred when they spoke about the emotional events in a mood-congruent voice style: fast and loud in the case of fear and anxiety, and slow and soft in the case of sadness or depression. Mood-incongruent voice styles canceled the heightened levels of CV arousal normally associated with these negative emotions. The voice-style manipulation had no significant effect on the participants' levels of CV arousal during the neutral discussions. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Synthesis and analysis of mixed chlorinated-fluorinated dibenzo-p-dioxins and dibenzofurans and assessment of formation and occurrence of the fluorinated and chlorinated-fluorinated dibenzo-p-dioxins and dibenzofurans

Despite the use of multimodal therapy, higher-grade glioma is still uniformly fatal in the adult population. There is a considerable difference between the length of survival in each given patient, even within the same tumor type and malignancy grade group, suggesting that there are factors that might differentially influence outcome. To identify such factors, 107 patients with anaplastic or malignant glioma were retrospectively investigated. Clinical parameters and paraclinical data on the p53, mdm2, and EGFR genes at the DNA or protein level were evaluated by univariate analysis and Cox proportional hazards regression modeling. Kaplan-Meier survival estimation demonstrated that immunohistochemical positivity for mdm2 protein in patients with anaplastic astrocytoma or with glioblastoma multiforme was associated with a shorter survival time (p = 0.02). P53 gene mutations and immunopositivity for the epidermal growth factor receptor (EGFR) protein were not significantly related to poor prognosis. The Cox proportional hazards model revealed immunohistochemical positivity for p53, mdm2, or for both of them, the presence of postoperative irradiation, and the extent of surgical resection of tumor to be variables significantly associated with prolonged survival. EGFR overexpression, age over 60 years, and Karnofsky performance score below 40 points did not significantly shorten survival time. In conclusion, the present study identified immunohistochemically detected mdm2-protein overexpression as a statistically significant negative prognostic parameter in patients bearing anaplastic or malignant glioma. Association analysis of variables revealed a possible correlation between mdm2 and p53, which is also consistent with the biological interaction mode of both proteins in vivo.     

Sexuality and aging--usual and successful

BACKGROUND: As aging research increasingly reflects an effort to dissociate true time-driven changes from those that can be improved, sexuality in later life remains largely unexplored. Several problems are evident. There is a lack of normative data, a lack of a conceptual framework relating to the biology, psychology, and sociology of sex, and an attitudinal resistance that obscures the entire topic. METHODS: We conducted a three-part instructional series on major topics involved with sexuality and aging. We surveyed our group of attendees (n 158, average age 68 for males, 65 for females) before and after the series. RESULTS: A remarkably robust sex life was evidenced by both the men and the women, even until advanced old age. Yet, a substantially decreased involvement was reported from 10 years earlier. Despite current activities, people of both sexes wished they were participating even more than they currently were. Impotency was identified as the major negative feature for the men; relationship problems were for the women. A questionnaire 6 months after the series reported improved sexual attitudes, but no change in sexual activities from the earlier survey. CONCLUSION: Sexuality is a major quality-of-life issue which persists into old age. Our study showed that the usual sexual practices reported by our group were not considered by them to be ideal. The intervention of this instructional series provided improved sexual attitudes but not performance. Additional studies are encouraged.     

Spondylolysis and spondylolisthesis and sports

Spondylolysis and spondylolisthesis occur predominantly in the lower lumbar spine. Besides congenital defects such as predisposition of spondylolysis the correlation between competitive sports activities and an increased incidence of spondylolysis is proved. In early stages, complete healing can be achieved by conservative treatment (abstinence from sports activities for 3 months, orthesis). Persistence of pain, neurologic symptoms and progression of vertebral slipping are indications for operative treatment (reconstruction of the isthmus, dorso-ventral spondylodesis). The exercise tolerance depends on the extent of instability, progression of vertebral slipping and clinical symptoms. The limits of exercise tolerance vary among the individual athletes and require the decision of the physician. Backstroke swimming, abdominal and back muscle strengthening exercises, and types of sport involving smooth movements are advisable. Sports education in school is possible without restriction in patients with stable spondylolysis and in those with spondylolisthesis without unfavourable concomitant factors.     

Larks and owls and health, wealth, and wisdom

OBJECTIVE: To test the validity of Benjamin Franklin's maxim "early to bed and early to rise makes a man healthy, wealthy, and wise." DESIGN: Cross sectional analysis of sleeping patterns in a nationally representative group of elderly people, and longitudinal investigation of mortality. SETTING: Eight areas in Britain (five in England, two in Scotland, and one in Wales). SUBJECTS: 1229 men and women aged 65 and over who in 1973-4 had taken part in a survey funded by the Department of Health and Social Security and for whom data on sleeping patterns, health, socioeconomic circumstances, and cognitive function had been recorded. MAIN OUTCOME MEASURES: Self reported income, access to a car, standard of accommodation, performance on a test of cognitive function, state of health and mortality during 23 years of follow up. RESULTS: 356 people (29%) were defined as larks (to bed before 11 pm and up before 8 am) and 318 (26%) were defined as owls (to bed at or after 11 pm and up at or after 8 am). There was no indication that larks were richer than those with other sleeping patterns. On the contrary, owls had the largest mean income and were more likely to have access to a car. There was also no evidence that larks were superior to those with other sleeping patterns with regard to their cognitive performance or their state of health. Both larks and owls had a slightly reduced risk of death compared with the rest of the study sample, but this was accounted for by the fact that they spent less time in bed at night. In the study sample as a whole, longer periods of time in bed were associated with increased mortality. After adjustment for age, sex, the presence of illness, and other risk factors, people who spent 12 or more hours in bed had a relative risk of death of 1.7 (1.2 to 2.5) compared with those who were in bed for 9 hours. The lowest risk occurred in people who spent 8 hours in bed (adjusted relative risk 0.8; 0.7 to 1.0). CONCLUSION: These findings do not support Franklin's claim. A "late to bed and late to rise" lifestyle does not seem to lead to socioeconomic, cognitive, or health disadvantage, but a longer time spent in bed may be associated with increased mortality.     

深云立交桥梁检测及加固改造

根据深云立交桥梁的检测结果，对该桥目前的整体状况、工作状态，及其使用情况做出综合评价，对桥的病害原因进行了分析，并提出合理的加固方案。     

关于摩尔浓度及其与硬度转换关系问题的讨论

众所周知，国际单位制物质的量采用摩尔(mol)表示，近几年出版的给排水专业书籍，为了与国际单位制接轨，逐渐将摩尔的使用频率不断提高，被给排水技术人员广泛应用的新版给排水设计手册，将表示物质浓度的单位“当量／升”或“毫克当量／升”．改为mol／l或mmol／l，虽然编者对其基本单元定义作了说明，但在实际运用上仍会出现误解，     

《儿子与情人》的语码转换与男女二元对立

劳伦斯小说《儿子与情人》一个鲜明的语言特色就是标准英语和当地方言频繁的语码转换。莫瑞尔用方言来对抗妻子,而妻子坚持用标准英语,偶尔也用方言来讽刺、挖苦丈夫。语码转换反映了劳伦斯男女二元对立的哲学思想。     

抗腐蚀高强耐磨涂料研发与应用

介绍了抗腐蚀高强度耐磨涂料的研制和开发，以及用作柳钢球团回转烘干机刮板保护涂层的应用效果。