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1.
This work contains the results of the aerosol mass size distribution and preliminary studies on concentrations and size distribution of heavy metals (Pb, Zn, Cu, Mn, Fe and Cd) in indoor and outdoor environment in Upper Silesia (the highly industrialized region in the southern part of Poland). In studies, the measurements of aerosol concentration, mass size distribution, and evaluation of heavy metals concentration were made from December 1992 to April 1994 in some apartments in five towns in Upper Silesia and in one village in the Beskidy Mountains in both indoor and outdoor environments. The particles were fractionated in Andersen cascade impactor. The sampling time was 6-7 days and 4-5 days for indoor and outdoor respectively. Aerosol particulates were collected on A-type glass fiber collection substrate used later for determination of heavy concentrations by atomic absorption spectrophotometry (AAS 3, Carl Zeiss Jena). The dust was mineralized by the means of the mixture of hydrofluoric and nitric acids. The results of mass size distribution as well as the measurements of TSP for indoor and outdoor aerosol show that the main source of particulate matter indoors, in this region, are heavy polluted outdoor air and cigarette smoking. It can be said that, except homes in Knurów and Sosnowiec with hard smokers, the indoor levels of particulate pollution were significant lower than the outdoors levels. Whenever in the indoor environment appear additional source of particulate emission situation can changed. When we compare mass size distribution for outdoor aerosol and indoor aerosol contaminated by tobacco smoke, we can observed considerable increase of indoor aerosol level in the 0.33-0.54 microns size range. Besides, indoor aerosol status may be changed by coal stove emission (displacement of maximum peak to direction of coarse particles). The observed differences in concentration of particulate matter may also indicate the important differences in chemical and physical nature of particles caused by the air filtration and absorption during migration of ambient air into the indoor environment. On the base of comparison of the heavy metals concentrations of fine and coarse fraction and their indoor/outdoor ratio in five selected towns in Upper Silesia it can be said that the level of heavy metals in indoor aerosol is lower than in outdoor (except Pb and Cd) what suggest that migration of ambient air into the homes is a major process which give indoor air contamination of heavy metals.(ABSTRACT TRUNCATED AT 400 WORDS)  相似文献   

2.
Passive measurements of outdoor radon and thoron concentrations were conducted from June 1992 to June 1993 at a monitoring station over a soil area (10 m x 6 m) in Chiba city, Japan. The measurement period was divided into 4 parts to investigate seasonal variations of radon and thoron concentrations. Ten passive radon-thoron discriminative dosimeters (R-T dosimeters) were placed in duplicate at 5 different altitudes to show the vertical distributions of outdoor radon and thoron concentrations. Outdoor radon concentrations showed no significant difference within 1.0 m above the ground, and the annual average of outdoor radon concentration was 3.85 +/- 0.19 (SE) Bq m-3. Annual averages of outdoor thoron concentrations at 0.04, 0.15, 0.25, 0.70, and 1.0 m above the ground were 40.5 +/- 4.4, 22.5 +/- 3.7, 13.9 +/- 3.1, 9.5 +/- 2.9 (SE) Bq m-3, and < 9.0 Bq m-3; the lower detection limit of the dosimeter, respectively, and their vertical profiles, n(z) (Bq m-3), were expressed well by the formula n(z) = alpha z beta. Vertical profiles of the atmospheric turbulent diffusion coefficient were also estimated from the observed thoron profiles, as expressed by the power function K(z) = AzB, of which B values were estimated to vary from 1.034 to 1.609 if averaged thoron exhalation rates during the measurement periods were within 0.3 to 2.8 (Bq m-2 s-1).  相似文献   

3.
A portable personal air pollution sampler was used to measure the exposure of twenty children to respirable particulates, sulfur dioxide, and nitrogen dioxide over a 24-hour period. Particulate exposures were significantly higher among children who lived with one or more smokers, and exceeded the primary air quality standard in nineteen of the twenty subjects. To a large extent, an individual's respirable particulate load appears to be determined by exposure to indoor rather than outdoor pollutants.  相似文献   

4.
Concentrations of HCH and DDT in soil, water and whole blood were determined in two areas under malaria control. These were, (i) bioenvironmental control of malaria at BHEL, and (ii) residual spraying of insecticides in rural and urban area of Bahadrabad PHC of Hardwar district. Mean concentrations of HCH in soil and whole blood samples from BHEL was 2.26 micrograms/kg and 1.20 micrograms/l and from Bahadrabad 61.12 micrograms/kg and 24.3 micrograms/l respectively. Similarly, the mean concentration of DDT in soil and whole blood from BHEL was 3.68 micrograms/kg and 4.71 micrograms/l, while in Bahadrabad 270.51 micrograms/kg and 38.13 micrograms/l respectively. HCH and DDT were never detected in any water samples from BHEL area, while the mean concentration of these compounds in water of Bahadrabad area was 0.18 and 0.07 microgram/l respectively. Residual level of HCH and DDT were 27 and 73.5 times higher in soil and 20.2 and 8.1 times higher in whole blood samples from Bahadrabad as compared to their corresponding values from BHEL respectively.  相似文献   

5.
To investigate the validity of outdoor particulate matter with a 50% cutoff diameter of 10-microm (PM10) concentrations as a measure of exposure in time series studies, the association between personal and outdoor concentrations, within subjects, over time was investigated. Repeated measurements of personal, indoor, and outdoor PM10 were conducted among 37 nonsmoking, 50- to 70-year-old adults, living in Amsterdam, Netherlands, 1994. Regression analyses were conducted for each subject separately, and the distribution of the individual regression and correlation coefficients was investigated. Furthermore, the extent to which differences among personal, indoor, and outdoor concentrations could be explained was studied. The median Pearson's R between personal and outdoor concentrations was 0.50. Excluding days with exposure to environmental tobacco smoke (ETS) improved the correlation to a median R of 0.71. The estimated cross-sectional correlations were lower, 0.34 and 0.50, respectively. Outdoor concentrations (mean, 42 microg/m3) exceeded indoor concentrations (mean, 35 microg/m3) but underestimated personal exposures (mean, 62 microg/m3). The major part of the difference between personal and outdoor concentrations could be attributed to exposure to ETS, living along a busy road, and time spent in a vehicle. The results show a reasonably high correlation between personal and outdoor PM10 within individuals, providing support for the use of ambient PM10 concentrations as a measure of exposure in epidemiologic studies linking the day-to-day variation in particulate matter air pollution to the day-to-day variation in health endpoints such as mortality, hospital admissions, respiratory symptoms, and lung function.  相似文献   

6.
Nitrogen dioxide levels were measured in 80 homes in the Latrobe Valley, Victoria, Australia, using passive samplers. Some 148 children between 7 and 14 yr of age were recruited as study participants, 53 of whom had asthma. Health outcomes for the children were studied using a respiratory questionnaire, skin prick tests, and peak flow measurements. Nitrogen dioxide concentrations were low, with an indoor median of 11.6 microgram/m3 (6.0 ppb), and a maximum of 246 microgram/m3 (128 ppb). Respiratory symptoms were more common in children exposed to a gas stove (odds ratio 2.3 [95% CI 1. 0-5.2], adjusted for parental allergy, parental asthma, and sex). Nitrogen dioxide exposure was a marginal risk factor for respiratory symptoms, with a dose-response association present (p = 0.09). Gas stove exposure was a significant risk factor for respiratory symptoms even after adjusting for nitrogen dioxide levels (odds ratio 2.2 [1.0-4.8]), suggesting an additional risk apart from the average nitrogen dioxide exposure associated with gas stove use. Atopic children tended to have a greater risk of respiratory symptoms compared with nonatopic children with exposure to gas stoves or nitrogen dioxide, but the difference was not significant.  相似文献   

7.
There are different ventilation control methods for outdoor air quantity in air-conditioned spaces to reduce the energy consumed in cooling the outdoor air. Demand controlled ventilation (DCV) is an important strategy to control the outdoor air quantity. However, the current practice in DCV systems creates several problems for air-conditioned office buildings. Although metabolic carbon dioxide (CO2) concentration is mainly used as a surrogate indicator for ventilation adequacy, the conventional DCV system does not seriously consider the placement location of the CO2 sensor, and it does not take into account the adverse effects of the consequential increase in pollutant concentrations in the indoor space when the fresh airflow rate is reduced. In this study, a long period of subjective and objective measurements were conducted in an occupied office to examine its suitability for conversion to a new demand controlled ventilation system (nDCV). After the feasibility investigation, an nDCV system was developed to optimize the energy consumed for outdoor air ventilation while providing the desirable thermal comfort and indoor air quality. The true optimization of this nDCV is achieved by a new concept of the optimized indoor air quality window which determines the most representative locations for the indicator sensors. A minimum ventilation rate is determined by a calibration procedure for the pollutant inventory of a building, taking into account the infiltration characteristics. Radon gas, which is a notorious carcinogenic indoor pollutant, is used as a reference to determine the minimum fresh airflow rate. The findings show that this nDCV system reduced 16% of fresh air cooling energy consumption without jeopardizing the thermal comfort and indoor air quality.  相似文献   

8.
BACKGROUND: In coastal Australia, mean house-dust-mite allergen concentration is 20-40 times higher in homes than in public buildings. Allergen concentrations in university colleges, which share some characteristics of both homes and public buildings, are not known. The study aimed to compare bed mite-allergen concentration in colleges with local homes. METHODS: Mattress dust was collected from three colleges (n = 60 in each) and local homes (n = 68) during summer. Der p 1 was measured by ELISA. Information was collected on the floor plan of the colleges, cleaning practices, age of building, and orientation of room. RESULTS: Most college mattresses (94%) had Der p 1 concentrations less than the mean of homes in the same climate. The geometric means of Der p 1 in the mattresses of the colleges were as follows: A, 8.9 micrograms Der p 1/g fine dust (95% CI 6.9, 11.5); B, 1.9 (1.5, 2.3); and C, 1.5 (1.2, 2.0), compared to homes, 22.5 (17.6, 28.7). The percentages of college mattresses with less than 2 micrograms/g were 7%, 48%, and 58%, respectively, compared to 4% for homes. Higher Der p 1 concentrations were weakly associated with age of building in college A, and orientation in college B. Der p 1 concentrations were independent of floor level and age of mattress. CONCLUSIONS: These findings indicate that low allergen concentrations are achievable without extreme hygiene and cleaning measures in a climate which supports mite proliferation in homes.  相似文献   

9.
Hydride generation atomic absorption spectrometry was used to determine the selenium concentrations in 130 samples of human serum from a control group of inhabitants in the southern part of the province of Granada (Spain). The mean selenium concentration in serum was 74.9 micrograms/l. This concentration did not vary significantly (P > 0.05) in relation to the sex of the subject, with concentrations of 80.6 micrograms/l in men and 70.7 micrograms/l in women. These mean values correspond to a mean daily dietary selenium intake of 50.4 micrograms per day in men and 44.6 micrograms per day in women. A considerable number of the individuals in the study area therefore have a daily selenium intake lower than the recommended dietary allowance of 70 micrograms per day for men and 55 micrograms per day for women. Likewise, the measured selenium concentrations in the basic health zones of the area were not statistically different (P > 0.05). The differences in selenium concentration between subjects in coastal zones and mountainous zones are therefore not significant.  相似文献   

10.
This study reports the first field measurements of airborne hexavalent chromium (Cr(vi)) in southwestern Ontario. Hexavalent chromium was identified as an inhalation carcinogen and an air toxic of concern during the 1991-93 Windsor Air Quality Study. The results of that study indicated that approximately 20% of the routinely monitored ambient airborne chromium (Cr) was in the hexavalent form. In addition, the range of carcinogenic health risks attributable to airborne Cr(vi) was determined to be between 1.4 x 10(-5) and 3.0 x 10(-4) for people living in the Windsor area. During the summer of 1993, analyses of concurrent indoor and outdoor 24-hour air quality samples taken at 33 residences in Hamilton resulted in geometric mean Cr(vi) concentrations of 0.20 ng/m3 and 0.55 ng/m3, respectively, and little or no relationship between the indoor and outdoor sample sets. During the summer of 1994, an airborne Cr(vi) size-fraction study was conducted in Hamilton, the results of which suggested that the majority of the Cr(vi) was in the inhalable fraction.  相似文献   

11.
An exploratory program was undertaken to determine the feasibility of measuring the indoor air concentration of 210Pb. Low flow rate pumps and membrane filters were used to collect samples in an office. The air filter samples were stored for 1.6 y and 210Po was chemically separated and measured by alpha spectrometry. Unsupported 210Po was also determined in air samples collected at a later time. The average air concentrations were 150 microBq 210 Pb m-3 and 12 microBq 210Po m-3. The average indoor to outdoor ratio of 210Pb in air is estimated to be 0.25.  相似文献   

12.
A Meta-analysis was conducted on 107 original epidemiological papers published between 1980 and 1993 on the respiratory health impact of suspended particles, sulfur dioxide, ozone and nitrogen dioxide. These are the usual air quality indicators that are monitored in urban ambient air. The range of exposures that were studied (averages and 90th percentiles are respectively up to 88, 83, 124 and 53 mu/m3 (averages) and 180, 147, 234 and 131 micrograms/m3 (90th percentile) for each of the four pollution indicators) allowed assessment of dose-response functions for irritative pulmonary conditions (cough and/or asthma episodes) and respiratory function (FEVI and peak expiratory flow). The dose-response functions seem linear in the range of observed concentrations, with nitrogen dioxide showing the least consistent association across different health indicators. When applied to exposures measured as a 100 micrograms/m3 increase of pollutant's concentrations compared to low background values, the average relative risks of airway irritation (cough and/or asthma épisodes) range, according to the pollutant, from 1.08 to 1.47; average relative decreases of respiratory function amount to 1.1 to 2.2%. The effects are most often stronger among young subjects. The results of this study, when applied to air pollution concentrations in the range of values that were observed in this study, should foster health risk assessment studies in places where population air pollution exposures are available.  相似文献   

13.
In this study, we investigated indoor air quality and symptoms of respiratory illness in 264 nursing workers at 28 day-care centers in Taipei. Geometric mean concentrations of indoor and outdoor bacteria were 735 colony-forming units in air (CFU/m3) and 384 CFU/m3, respectively. In addition, geometric mean concentrations of indoor and outdoor fungi were 1,212 CFU/m3 and 1,032 CFU/m3, respectively. Aspergillus, Cladosporium, and Penicillium-microfungi that occurred most commonly-were found indoors and outdoors. Geometric mean concentrations of house dust mite allergens, Der p I and Der p V, were 58 ng/g dust and 14 ng/g dust, respectively. In addition, the observed high prevalence of dampness or mold problems in the day-care centers indicated that dampness was very common in this subtropical region. We found a significant relationship between dampness and work-related sick building syndrome in the day-care-center workers. Furthermore, concentrations of fungi were lower in the day-care centers equipped with air conditioners/air cleaners than in centers that lacked such equipment. Also, Aspergillus was associated strongly with work-related sick building syndrome in the day-care-center workers.  相似文献   

14.
The diagnosis of GH deficiency (GHD) in the elderly is based at present on the peak GH concentration during a stimulation test. We have now evaluated the performance of urinary GH (uGH), urinary insulin-like growth factor I (uIGF-I), and urinary IGF-binding protein-3 (uIGFBP-3) in the diagnosis of GHD in this group. Twenty GHD elderly patients with a history of pituitary disease and a peak GH response to arginine stimulation of less than 3 ng/mL (15 men and 5 women; age, 61.1-83.4 yr) and 19 controls (12 men and 7 women; age, 60.8-87.5 yr) were studied. GH secretion was assessed by 24-h profile and expressed as the area under the curve (AUCGH). Serum (s) IGF-I and sIGFBP-3 were measured in a single morning, fasted sample. Urinary GH, uIGF-I, and uIGFBP-3 were measured in a 24-h urine sample collected over the same interval as the GH profile, and results were expressed as total amount excreted in 24 h (tuGH24, nanograms; tuIGF-I24, nanograms; tuIGFBP-3(24), micrograms). Data are presented as the mean +/- SD, except for AUCGH, tuGH24, and tuIGFBP-3(24), which are presented as the geometric mean (-1, +1 tolerance factor). AUCGH, sIGF-I, and sIGFBP-3 were significantly lower in GHD subjects than in controls. Total uGH24 was lower in GHD subjects, but tuIGF-I24 and tuIGFBP-3(24) excretion were not different in the two groups. AUCGH provided the best separation between GHD and control subjects, whereas there was substantial overlap for sIGF-I, sIGFBP-3, and tuGH24. In both groups sIGF-I was correlated to sIGFBP-3 (GHD, r = 0.75; controls, r = 0.65; both P < 0.01), whereas tuIGF-I24 was not correlated to tuIGFBP-3(24) in either group. Moreover, tuIGF-I24 and tuIGFBP-3(24) were not related to their respective serum concentrations in either group. Total uGH24 was correlated with AUCGH only in controls (r = 0.54; P < 0.05). These data demonstrate that urinary GH and urinary and serum IGF-I and IGFBP-3 are not suitable diagnostic markers for GHD in elderly subjects.  相似文献   

15.
An investigation of residences located above dry cleaning facilities was conducted to determine whether indoor and outdoor air concentrations of the dry cleaning solvent tetrachloroethene (perchloroethylene, PCE) were elevated compared to residences not near a dry cleaning facility. Data were also collected on the dry cleaners' operating conditions and equipment. Significantly elevated levels of PCE were found in the indoor air of each of six apartments located above dry cleaners compared to control residences for both day and night samples. The PCE concentrations in outdoor air near the dry cleaners were also significantly elevated compared to control locations and were lower than the concentrations measured indoors. The type of dry cleaning machine was significantly associated with the concentration of PCE found in the apartment above. A strong correlation was also found between the day and night PCE levels in the study apartments.  相似文献   

16.
Rat lung fibroblasts were cultured for 24 and 48 h with UICC standard reference asbestos samples of amosite, crocidolite or Canadian chrysotile at various concentrations, and thiobarbituric acid-reactive substances (TBARS) in the media and the cells were measured. Tests by the trypan blue dye-exclusion method showed that cell viability was 80 +/- 5% (mean +/- SD) and 71 +/- 6% when cultured for 48 h in the presence of 500 micrograms ml-1 of amosite and crocidolite, respectively, but was not affected by chrysotile. In cultures for 24 and 48 h, both chrysotile and crocidolite at > 250 micrograms ml-1 significantly increased TBARS in the medium, whereas amosite did so at > 500 micrograms ml-1. TBARS in the cells was not increased significantly by chrysotile at any concentration in the cultures for 24 and 48 h, but crocidolite at > 250 micrograms ml-1 significantly increased TBARS in the cells when cultured for 24 or 48 h. Although amosite at all concentrations tested did not increase significantly TBARS in the cells of the 24-h culture, it did increase TBARS significantly in the cells when cultured for 48 h at a concentration of 500 micrograms ml-1 amosite. The increases of TBARS in media of the cultures with asbestos were accompanied by increases of lactate dehydrogenase (LDH) activity in the media, indicating the leakage of the enzyme from the cell into the media. The activity of LDH and the amount of TBARS showed a good correlation with each other, with a significant correlation coefficient value of 0.655.(ABSTRACT TRUNCATED AT 250 WORDS)  相似文献   

17.
The aim of this study was to determine and compare lead concentrations in breast milk between urban and rural women. Colostrum from 51 women living in the city of Thessaloniki (exposed to increased air lead concentration, 0.54 micrograms/m3) and from 40 women living in rural areas (exposed to significantly lower air lead concentrations) was analyzed by atomic absorption spectrometry. Urban women showed slightly higher lead concentrations (mean +/- SD: 0.090 +/- 0.029 micrograms/ml) than rural women (mean +/- SD: 0.084 +/- 0.024 micrograms/ml). This difference was not statistically significant. These results suggest that the lead content of human milk is not influenced by the concentrations of this environmental pollutant in the air.  相似文献   

18.
Asthma is an inflammatory disease of the airways, and exacerbations of this disease have been associated with high levels of air pollution. The objective of this study was to examine whether ambient air pollution and/or allergen exposure induces inflammatory changes in the upper airways of asthmatics. Sixty patients with intermittent to severe persistent asthma visited the Hospital's Out Patient Clinic every 2 wk for a period of 3 mo, and on each visit a nasal lavage was obtained. Associations between nasal inflammatory parameters and seasonal allergens and/or air pollution exposures were analyzed using linear regression analysis. The study ran from July 3 to October 6, 1995, during which period ozone (8-h mean: 80 micrograms/m3) and PM10 (24-h mean: 40 micrograms/m3) were the major air pollutants; the major aeroallergen was mugwort pollen (24-h mean: 27 pollen grains/m3). Effects on both cellular and soluble markers in nasal lavage were demonstrated for both ozone and mugwort pollen, but not for PM10. Ambient ozone exposure was associated with an increase in neutrophils (112% per 100 micrograms/m3 increase in 8-h average ozone concentration), eosinophils (176%), epithelial cells (55%), IL-8 (22%), and eosinophil cationic protein (ECP) (19%). Increases in environmental mugwort pollen counts were associated with an increase in nasal eosinophils (107% per 100 pollen/m3) and ECP (23%), but not with neutrophils, epithelial cells, or lL-8. This study demonstrated that both ambient ozone and allergen exposure are associated with inflammatory responses in the upper airways of subjects with asthma, although the type of inflammation is qualitatively different.  相似文献   

19.
The naturally radioactive but chemically inert gas, radon, is formed from the radioactive decay of radium which is part of the uranium series. Radon gas, which has a half life of 3.8 days, must escape from soil particles through air-filled pores in order to enter the atmosphere following the decay of radium. The concentration of radon in the atmosphere varies, depending on the place, time, height above the ground and meteorological conditions. It is thus an inescapable source of radiation exposure, both at home and at work. The potential hazards posed by exposure to radiation from indoor radon gas and its daughter products are of great concern worldwide. Noting of an excessive lung cancer risk among several groups of underground miners exposed to radon and its daughter products, studies on radon concentrations in the workplace and in dwellings have been conducted in many countries. The results have shown that the distribution of radon concentrations are approximately lognormal from which population weighted; the arithmetic mean of radon concentration of 40 Bq.m-3 has been adopted worldwide for dwellings and workplaces. The principal methods for reducing a high indoor radon concentration are: reducing the radon supply by reversing the pressure difference between the building and the soil; raising the resistance of the foundations to soil gas entry; removing the radon sources such as water or underlying soil; diluting the concentration by increasing the ventilation rate; and reducing the concentration of radon progeny by filtering and increasing the circulation of indoor air. Buildings which have a radon concentration higher than 200 Bq.m-3 should be investigated by the national authorities concerned; meanwhile, householders should be advised to take simple temporary precautions, such as increasing ventilation, until a permanent remedy can be effected.  相似文献   

20.
In 1996, 24-h food duplicate samples were collected from two groups of 50 non-smoking women each; one group was in Jinan, the capital city of Shandong Province in China, and the other in a farming village in the Zhangqiu area some 30 km away from the city. The people in the village took significantly more dietary lead (46 micrograms/day) than their counterparts in the city (26 micrograms/day), and blood lead concentrations (35 and 50 micrograms/l for the urban and the rural people, respectively) were in parallel with the dietary lead intake. Search for cereals as the determinants of dietary lead intake and blood lead concentration by multiple regression analysis showed that maize was the most influential source of dietary lead intake among the four common cereals of wheat, rice, foxtail millet (to be called just millet) and maize, whereas millet was the leading determinant of the blood lead level among the four cereals although the influential power was weaker than millet for dietary lead. Lead content in maize (47 ng/g) and millet (47 ng/g) was twice or even more times higher than the levels in wheat (26-30 ng/g) and rice (20-21 ng/g). The significant roles of non-rice/non-wheat cereals such as millet and maize as possible dietary lead sources for farming populations are discussed.  相似文献   

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