影响煤质快速灰分仪测定准确性的因素分析

针对洗煤灰分常规测定方法时间长,不能及时反映洗煤质量的问题,采用了XL-6338A快速煤质分析仪测定洗煤灰分。分析了该仪器测定灰分时影响其准确性的因素。通过各因素下该仪器测定数据与重量法测定数据的多次对比,得出把洗煤试样粒度控制在≤3mm、水分控制在≤10%、堆密度控制在每桶(2.53±0.05)kg,可得到较准确的灰分测定数据。     

如何保证在线气相色谱仪的分析准确性

如何保护在线气相色谱仪能够得到准确的分析数据是个十分重要的问题,分析仪的温度、载气的流速和纯度、样品的气化程序、标准气体的混合均匀程度以及色谱处理参数等因素都将对此产生影响。结合聚丙烯生产过程中的丙烯中氢气含量在线气相色谱仪,对这一问题进行比较全面的讨论。     

Validation Study of a New Random-Access Chemiluminescence Immunoassay Analyzer i-TRACK10® to Monitor Infliximab and Adalimumab Serum trough Levels and Anti-Drug Antibodies

Background. Monitoring of biological TNF inhibitors is a very important tool to guide clinical decisions using specialized algorithms, especially in gastroenterology. A new chemiluminescent instrument (i-TRACK^10® from Theradiag) could replace ELISA techniques to calculate the dosage of drugs and anti-drug antibodies. In this bi-centric study, we explored the analytical performances of i-TRACK^10® using manual or automated (DS2^®) ELISA Lisa-Tracker^® assays, and compared the results. Patients and methods. Intra- and inter-run performances were evaluated with i-TRACK^10® in two different laboratories and for two different ranges of values for infliximab, adalimumab, and their respective antibodies. Patients’ samples were used in the labs to compare the results obtained between the new instrument and either the manual Lisa-Tracker^® or the automated DS2. Results. Intra- and inter-run performances were satisfactory, with values between 1.8% and 16.1% (for inter-run imprecision at low/medium values of infliximab). Results were generally comparable between assays. with the lowest value of correlation at 0.59 (anti-adalimumab dosage between i-TRACK^10® and manual ELISA). Most often, values of drugs and anti-drug antibodies were higher with i-TRACK^10® than with manual ELISA assay, and correlation values were better with automated ELISA. Agreements were globally acceptable, and the lowest coefficients of 0.7 was obtained for adalimumab values between i-TRACK^10® and the two ELISA methods, and for anti-adalimumab values between i-TRACK^10® and manual ELISA. The type of assay can potentially induce a change in the class of patients and lead to divergent therapeutic decisions. Conclusions. The new random-access instrument i-TRACK^10® presents many advantages in a routine laboratory: rapidity, the possibility of standardization, usability, and expansion of the measurement range. Despite the relatively good agreement of results, it is preferable to use the same assay in longitudinal follow-up of a patient, because quantitative results were not completely equivalent especially for anti-drug antibodies.     

元素分析仪法测定氧含量的研究

Vario ELⅢ元素分析仪在分析有机化合物中的C、H、O、N、S元素含量时能够达到相当高的精度。但对元素有机化合物的测量范围有限(由于其含有特殊的杂原子),为了解决其在测量有机元素化合物中氧元素方面的局限性,扩大仪器的使用范围,本研究以测定简单氧化物中的氧含量代替元素有机化合物,结果表明Vario ELⅢ元素分析仪也可以用来测定部分氧化物和元素有机化合物中的氧含量。并通过测定大量氧化物,结合元素周期表找出了可测元素的分布规律,对以后使用Vario ELⅢ元素分析仪测定样品的分析工作具有指导意义。     

浅对烟气分析仪在污染源监测中准确性的探讨

文章针对烟气分析仪在污染源监测中容易引起监测数据偏差的因素做系统分析,结合烟气成分、电化学气体传感器工作原理及适用性、气体交叉干扰特性、做好仪器的检查校准和仪器的正确操作与预处理等方面,提出使用过程中的质量控制要点,以保证烟气分析的准确性。     

基于物联网技术的环境空气质量自动监测站智能化建设与管理

文章综合目前我国环境空气质量自动监测工作需求和管理分析说明智能化在我国大气环境监测中的应用和发展趋势,为更好的将物联网技术应用在我国大气环境监测提供参考,为环境保护提供了新技术、新方法和新思路。     

An evaluation of the Diamat HPLC analyser for simultaneous determination of haemoglobins A2 and F

The authors describe a modification of the instrumental parameters of the Diamat fully automated HPLC system for Hb A₂ assay (Bio-Rad Laboratories, Milan, Italy) in order to obtain simultaneous determination of Hb A₂ and Hb F.Hb A₂ and Hb F measurements are reproducible (within-run CV 2.6%, with Hb A₂2.7%; 5.1%, with Hb F 1.3%) and accurate (from a comparison with two microchromatographic techniques for Hb A₂: r = 0.9639 and 0.9755; with two alkali denaturation procedures for Hb F: r = 0.9990 and 0.9952; with radial immunodiffusion, r = 0.9877). Assay linearity has been confirmed for Hb A₂ concentrations between 0 and 6.0%, and for Hb F between 0 and 60%. The data obtained from the analysis of some pathological samples for Hb Bart''s, Hb H, Hb J Sardegna, Hb Lepore and Hb S are in agreement with cellulose acetate electrophoresis analysis.The Hb A₂ reference intervals for normals (N = 597) and Beta-thalassemia carriers (N = 200) are respectively (95% limits) 2.02-3.27 and 3.92-5.90 in % units. Hb F values measured in normals (N = 968), in β-thal carriers (N = 302) and in δβ-thal carriers (N =3) have been found to be consistent with the usual diagnostic parameters.Some minor limitations emerged: the most relevant concerns Hb A_1c, which is overestimated with respect to a reference method (y = 1.217x + 0.16; N = 79; r = 0.9235). A probable interference from labile fractions is responsible for this Hb A_1c inaccuracy.     

基于硅胶除湿法提高振荡天平法颗粒物分析仪准确性的方法研究

根据振荡天平法颗粒物分析仪浓度测值误差产生的原因,论述现有气体除湿方法的优缺点,自主研发一款气溶胶连续除湿装置。首次提出以硅胶除湿的方式提高振荡天平法颗粒物分析仪准确度的原理和方法,并论证该方法的技术可行性。     

Functional Validation of Glutamine synthetase and Glutamate synthase Genes in Durum Wheat near Isogenic Lines with QTL for High GPC

Durum wheat (Triticum turgidum L. ssp. durum) is a minor crop grown on about 17 million hectares of land worldwide. Several grain characteristics determine semolina’s high end-use quality, such as grain protein content (GPC) which is directly related to the final products’ nutritional and technological values. GPC improvement could be pursued by considering a candidate gene approach. The glutamine synthetase (GS)/glutamate synthase (GOGAT) cycle represents a bottleneck in the first step of nitrogen assimilation. QTL for GPC have been located on all chromosomes, and several major ones have been reported on 2A and 2B chromosomes, where GS2 and Fd-GOGAT genes have been mapped. A useful and efficient method to validate a putative QTL is the constitution of near-isogenic lines (NILs) by using the marker found to be associated to that QTL. Here, we present the development of two distinct sets of heterogeneous inbred family (HIF)- based NILs segregating for GS2 and Fd-GOGAT genes obtained from heterozygous lines at those loci, as well as their genotypic and phenotypic characterizations. The results allow the validation of the previously identified GPC QTL on 2A and 2B chromosomes, along with the role of these key genes in GPC control.     

Compositional and optical properties of SiO x films and (SiO x /SiO y ) junctions deposited by HFCVD

In this work, non-stoichiometric silicon oxide (SiO _x ) films and (SiO _x /SiO _y ) junctions, as-grown and after further annealing, are characterized by different techniques. The SiO _x films and (SiO _x /SiO _y ) junctions are obtained by hot filament chemical vapor deposition technique in the range of temperatures from 900°C to 1,150°C. Transmittance spectra of the SiO _x films showed a wavelength shift of the absorption edge thus indicating an increase in the optical energy band gap, when the growth temperature decreases; a similar behavior is observed in the (SiO _x /SiO _y ) structures, which in turn indicates a decrease in the Si excess, as Fourier transform infrared spectroscopy (FTIR) reveals, so that, the film and junction composition changes with the growth temperature. The analysis of the photoluminescence (PL) results using the quantum confinement model suggests the presence of silicon nanocrystal (Si-nc) embedded in a SiO _x matrix. For the case of the as-grown SiO _x films, the absorption and emission properties are correlated with quantum effects in Si-nc and defects. For the case of the as-grown (SiO _x /SiO _y ) junctions, only the emission mechanism related to some kinds of defects was considered, but silicon nanocrystal embedded in a SiO _x matrix is present. After thermal annealing, a phase separation into Si and SiO₂ occurs, as the FTIR spectra illustrates, which has repercussions in the absorption and emission properties of the films and junctions, as shown by the change in the A and B band positions on the PL spectra. These results lead to good possibilities for proposed novel applications in optoelectronic devices.

PACS

61.05.-a; 68.37.Og; 61.05.cp; 78.55.-m; 68.37.Ps; 81.15.Gh     

基于C8051F020单片机技术的在线多参数水质分析仪的设计与应用

应用同一个微处理器C8051F020高速单片机技术,完成了电力工业水处理在线分析电导率、pH和Na＋多参数的测量。提高了仪表的性价比,易于管理和仪器的维护,通过现场试验分析各参数的测量达到了现场分析的要求。     

Depigmenting effect of <Emphasis Type="Italic">Cinnamomum cassia</Emphasis> Presl in B16F10 melanoma cells

To find efficient depigmenting agents, we examined several Chinese herbs for melanogenesis inhibition and toxicity. Cinnamomum cassia Presl exhibited low cytotoxicity at even high concentration (200 μg/ml). The effects on melanogenesis of cultured B16 melanoma cells, mushroom tyrosinase activity, and free radical scavenging activity were further assessed. The methanol extracts of this plant showed the suppression of melanin synthesis. Melanin content was dose-dependently decreased by this herb extract as compared with control cells. It also showed good anti-oxidative activity (IC₅₀=3.7 μg/ml) but no inhibition of mushroom tyrosinase activity. This result showed that Cinnamomum cassia Presl extract might be useful and safe as a new whitening agent in cosmetics.