ALDH2, ADH1B and alcohol expectancies: Integrating genetic and learning perspectives.

The present study evaluated associations of ALDH2 and ADH1B genotypes with alcohol expectancies and drinking behavior in a sample of Asian American young adults. In addition to assessing global alcohol expectancies, the authors developed a measure of physiological expectancies to evaluate an expectancy phenotype specific to the mechanism by which ALDH2 and ADH1B variations presumably influence drinking behavior. Compared with individuals with the ALDH2*1/*1 genotype, those with the ALDH2*2 allele reported greater negative alcohol expectancies, greater expectancies for physiological effects of alcohol and lower rates of alcohol use. ADH1B was not associated with alcohol expectancies or drinking behavior. Hierarchical models showed that demographic factors, ALDH2 genotype, and expectancy variables explained unique variance in drinking outcomes. Mediation tests showed significant indirect effects of ALDH2 on drinking frequency and peak lifetime consumption through expectancies. These results provide support for influences of genetic factors and alcohol sensitivity on alcohol-related learning and suggest the importance of developing biopsychosocial models of drinking behavior in Asian Americans. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Parental alcohol involvement and adolescent alcohol expectancies predict alcohol involvement in male adolescents.

Current models of adolescent drinking behavior hypothesize that alcohol expectancies mediate the effects of other proximal and distal risk factors. This longitudinal study tested the hypothesis that the effects of parental alcohol involvement on their children's drinking behavior in mid-adolescence are mediated by the children's alcohol expectancies in early adolescence. A sample of 148 initially 9–11 year old boys and their parents from a high-risk population and a contrast group of community families completed measures of drinking behavior and alcohol expectancies over a 6-year interval. We analyzed data from middle childhood (M age = 10.4 years), early adolescence (M age = 13.5 years), and mid-adolescence (M age = 16.5 years). The sample was restricted only to adolescents who had begun to drink by mid-adolescence. Results from zero-inflated Poisson regression analyses showed that 1) maternal drinking during their children's middle childhood predicted number of drinking days in middle adolescence; 2) negative and positive alcohol expectancies in early adolescence predicted odds of any intoxication in middle adolescence; and 3) paternal alcoholism during their children's middle childhood and adolescents' alcohol expectancies in early adolescence predicted frequency of intoxication in middle adolescence. Contrary to predictions, child alcohol expectancies did not mediate the effects of parental alcohol involvement in this high-risk sample. Different aspects of parental alcohol involvement, along with early adolescent alcohol expectancies, independently predicted adolescent drinking behavior in middle adolescence. Alternative pathways for the influence of maternal and paternal alcohol involvement and implications for expectancy models of adolescent drinking behavior were discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Alcohol expectancies and the risk for alcoholism.

The current study examined alcohol expectancies and drinking motives as correlates of alcohol involvement among adolescents at high and low risk for future alcoholism. Measures of alcohol expectancies, drinking motives, presumed personality risk for alcoholism, family history of alcoholism, and alcohol involvement were completed by 979 high school students. Alcohol expectancies and drinking motives were found to vary as a function of risk status. More important, the strength of the relations between alcohol expectancies or drinking motives and alcohol involvement varied as a function of risk status. Expectancies of altered social behavior were particularly associated with low-risk drinking. Expectancies of enhanced cognitive and motor functioning, expectancies of tension reduction, expectancies of deteriorated cognitive and behavioral functioning, personal motives, and power motives were particularly associated with high-risk drinking. These expectancies and motives are of potential prognostic significance in the development of alcoholism and may be important targets for modification in primary prevention programs. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Thinking and drinking: Alcohol-related cognitions across stages of adolescent alcohol involvement.

Alcohol-related cognitions, particularly expectancies for drinking and nondrinking and motives for nondrinking, are involved in the initiation, maintenance, and cessation of alcohol use and are hypothesized to play key roles in adolescent decision making. This study explored (a) the relationships between alcohol use expectancies, nondrinking expectancies, and nondrinking motives; (b) the roles of these cognitions across hypothesized developmental stages of adolescent alcohol use; and (c) the relationships between these cognitions and recent or intended future changes in drinking behavior in a cross-sectional sample. Surveys assessing alcohol use behaviors and attitudes were administered to 1,648 high school students. Heavier drinkers reported more positive alcohol use expectancies and fewer nondrinking motives than did lighter drinkers or nondrinkers; however, nondrinking expectancies only differed between nondrinkers and rare drinkers and all subsequent drinking classes. Alcohol use expectancies, nondrinking expectancies, and nondrinking motives differentiated students who recently initiated alcohol from those who had not, while nondrinking expectancies and nondrinking motives differentiated binge-drinking students who had made recent efforts to reduce/stop their drinking from those who had not. Intentions to initiate or reduce drinking in the coming month were also associated with these alcohol-related cognitions. Drinking and nondrinking expectancies and motives for not drinking may play critical roles in decisions to alter alcohol-use behavior during adolescence. Future exploration of temporal relationships between changes in alcohol-related cognitions and behavioral decision making will be useful in the refinement of effective prevention and intervention strategies. (PsycINFO Database Record (c) 2011 APA, all rights reserved)     

Perceived exposure to peer and adult drinking as predictors of growth in positive alcohol expectancies during adolescence.

This study investigated the effects of change in exposure to peer and adult drinking on changes in positive alcohol expectancies during adolescence. Covariance and mean structure analysis were used to model change in the predictors and in alcohol expectancies in a sample of southern California schoolchildren followed from Grades 5 to 10 (N?=?3,580). The sample was gender balanced and was predominantly White (51 %) and Hispanic (28%). Exposure to peer drinking and rate of change in exposure to peer and adult drinking were found to predict the rate of change in alcohol expectancies. These effects were particularly strong between Grades 5 and 7, suggesting the need for early intervention aimed to prevent the increase in positive alcohol expectancies. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Analysis of item response and differential item functioning of alcohol expectancies in middle school youths.

Drinking behavior in preadolescence is a significant predictor of both short- and long-term negative consequences. This study examined the psychometric properties of 1 known risk factor for drinking in this age group, alcohol expectancies, within an item response theory framework. In a sample of middle school youths (N = 1,273), the authors tested differential item functioning (DIF) in positive and negative alcohol expectancies across grade, gender, and ethnicity. Multiple-indicator multiple-cause model analyses tested differences in alcohol use as a potential explanation for observed DIF across groups. Results showed that most expectancy items did not exhibit DIF. For items where DIF was indicated, differences in alcohol use did not explain differences in item parameters. Positive and negative expectancies also systematically differed in the location parameter. Latent variable scale scores of both positive and negative expectancies were associated with drinking behavior cross-sectionally, while only positive expectancies predicted drinking prospectively. Improving the measurement of alcohol expectancies can help researchers better assess this important risk factor for drinking in this population, particularly the identification of those with either very high positive or very low negative alcohol expectancies. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

In search of the seven dwarves: Issues of measurement and meaning in alcohol expectancy research.

Discusses substantive issues in predicting drinking patterns from expectancies, as well as issues of content and measurement of the scales developed to measure these expectancies. In recent years, much research has suggested that alcohol expectancies—or the beliefs that individuals hold about the effects of alcohol on their behavior, moods, and emotions—are an important factor in motivating drinking behavior. Although measures of these expectancies have consistently been shown to be correlated with measures of alcohol use, conceptual and methodological problems remain to be addressed. In order to progress in understanding this potentially important psychosocial factor in abusive and nonabusive drinking, alcohol expectancy research, which has been atheoretical in nature, should attend to potential contributions from other areas of research in psychology. (PsycINFO Database Record (c) 2011 APA, all rights reserved)     

Activation of alcohol expectancies in memory in relation to limb of the blood alcohol curve.

Attempts to understand the mechanism by which alcohol expectancies might influence drinking have related activation of expectancies in memory to alcohol use. Limb of the blood alcohol curve, however, has not been considered. In the present study, 527 undergraduates completed the Anticipated Biphasic Alcohol Effects Scale and a drinking measure. Multidimensional scaling was used to map expectancies into memory network format, and likely activation of expectancies was empirically modeled. Heavier drinkers were most likely to activate positive and arousing expectancies associated with the ascending limb, whereas lighter drinkers were most likely to activate negative and sedating expectancies associated with the descending limb. These findings add to the literature suggesting that activation of expectancies in memory may be an important determinant of drinking behavior and a promising target for intervention strategies. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Coping With Distress by Eating or Drinking: Role of Trait Urgency and Expectancies.

The authors propose that trait urgency (the tendency to act rashly when distressed) is a risk factor for both alcohol abuse and bulimic symptoms, that disorder-specific expectancies influence whether one engages in one behavior or the other, and that expectancies moderate urgency's influence on those behaviors. Cross-sectional findings were consistent with the model. Problems from alcohol use were comorbid with binge eating and purging. Trait urgency was associated with both behaviors. Alcohol expectancies were associated with drinking levels and with problem drinking, but not with eating. Eating expectancies were associated with binge eating, but not with alcohol use or problems. Urgency's effect on binge eating was moderated by expectancies, but its effect on alcohol use and problem drinking was not. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Interactive effects of alcohol outcome expectancies and alcohol cues on nonconsumptive behavior.

Experimental research and popular belief suggest that, among its many effects, alcohol consumption reduces tension and facilitates aggression. Such observations could result from direct, pharmacological effects of alcohol on neural control of behavior but also may be accounted for by positing that drinking behavior activates mental representations of relaxation-related or aggression-related alcohol expectancies in long-term memory. Building on this latter view, in 2 experiments, the authors investigated whether rudimentary drinking-related cues, which presumably activate encoded alcohol expectancies, facilitate tension reduction and hostility in the complete absence of actual or placebo alcohol consumption. In Experiment 1, following contextual exposure to alcohol-related words, individuals with stronger expectancies that drinking reduces tension showed an increased willingness to meet with an opposite-gender stranger under relatively anxiety-provoking circumstances, suggesting that they experienced less apprehension regarding the meeting. Analogously, in Experiment 2, following near-subliminal exposure to alcohol-related words, individuals with stronger expectancies that drinking fosters aggression showed greater hostility toward a target person following an experimentally engineered provocation. Neither of the latter effects was obtained following exposure to nonalcoholic beverage words, which presumably did not activate alcohol outcome expectancy representations in long-term memory. Moreover, the strength of relevant, content-specific expectancies (i.e., for tension reduction or aggression, respectively) moderated alcohol cue exposure effects, but the strength of other expectancies (e.g., for sociability or sexual arousal) did not. Together, these findings demonstrate that exposure to rudimentary alcohol cues independently engenders expectancy-consistent behavior, thereby attesting to the remarkable breadth and subtlety of the behavioral impact of alcohol expectancy activation. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Alcohol expectancy priming and drinking behavior: The role of compatibility between prime and expectancy content.

According to information-processing models of alcohol use, alcohol expectancies constitute representations in long-term memory that may be activated in the presence of drinking-related cues, thereby influencing alcohol consumption. A fundamental implication of this approach is that primed expectancies should affect drinking only for those individuals who possess the specific expectancies primed. To test this notion, in the present study, participants were initially assessed on 3 distinct domains of positive alcohol expectancies. Approximately 1 week later, they completed an ad libitum drinking study during which only a single expectancy domain (sociability) was primed in the experimental condition. Consistent with predictions, following exposure to sociability primes but not control primes, individuals with stronger expectancies that alcohol would enhance sociability uniquely showed increased placebo consumption of nonalcoholic beer. These results, which demonstrate the moderating role of compatibility between the specific content of primes and that of underlying expectancies, offer new, direct support for memory network-based models of drinking behavior. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Alcohol-related expectancies predict quantity and frequency of heavy drinking among college students.

Alcohol-related expectancies covary consistently with consumption patterns; limited research also suggests that expectancies can predict future drinking behavior. However, the ability of expectancies to predict high-risk drinking has not been evaluated among college students. Participants were 140 undergraduates who completed an alcohol use assessment at 2 points in time, separated by. 1 month. Using multiple regression analyses, the author determined that alcohol-related expectancies accounted for a small but significant percentage of variance in each of 2 alcohol consumption variables. Global positive expectancies predicted maximum daily quantity, and sexual enhancement expectancies predicted the frequency of intoxication, even when controlling for baseline levels of both variables. These findings support alcohol abuse prevention efforts designed to modify cognitive expectancies. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

What makes group MET work? A randomized controlled trial of college student drinkers in mandated alcohol diversion.

Nationally, college drinkers exhibit the highest rates of alcohol consumption and represent the largest percentage of problem drinkers. Group motivational enhancement therapy (GMET) has been found to catalyze problem drinking reductions among college student samples. Although research supporting the use of single-session GMET in college samples (general and mandated) is emergent, no studies have evaluated a comprehensive model of the potential active ingredients of this group intervention. College students (N = 206; 88% White; 63% men; M age = 18.6) mandated to a university alcohol diversion program were randomly assigned to 1 of 3 conditions: the standard-of-care 2-session “Focus on Alcohol Concerns” education group (FAC), a single GMET, or a single alcohol information-only control group (AI) to evaluate the role of 5 putative mediators: readiness to change, self-efficacy, perceived risk, norm estimates, and positive drinking expectancies. At 3- and 6-month follow-ups, GMET students demonstrated greater reductions in problem drinking outcomes (drinks per drinking day, hazardous drinking symptoms, and alcohol-related problems). Of the 5 mediators proposed, only self-efficacy emerged as a significant mediator. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Expectancies versus background in the prediction of college drinking patterns.

Examined the alcohol expectancies of 321 17–40 yr old undergraduates as a function of Ss' drinking patterns and Ss' expectancies to demographic/background variables for their ability to predict problematic and nonproblematic drinking patterns. Ss completed a demographic data sheet, alcohol expectancy questionnaire, and customary drinking record. Factor analysis of Ss' self-reported drinking yielded 3 drinking styles: nonproblematic social drinking, frequent drinking with alcohol-related problems, and contextually determined alcohol consumption. Optimal alcohol expectancy and demographic/background predictors of each drinking style were selected and compared via multiple regression procedures. Predictor equation efficiency was then examined in a new cross-validation sample of 176 Ss. Results indicate that alcohol expectancies increased the predictability of college drinking patterns and that alcohol expectancies were differentially related to problematic and nonproblematic features of college drinking. (12 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Elementary School Drinking: The Role of Temperament and Learning.

Drinking in elementary school, despite its low base rate, has been shown to predict alcohol use in middle school (Wilson, Battistich, Syme, & Boyce, 2002), which in turn predicts alcohol abuse or dependence in young adults (Guo, Collins, Hill, & Hawkins, 2000). The authors report 1 of the 1st examinations of the relationship between personality and psychosocial learning risk factors and drinking behavior among elementary school students. Fifth-grade students completed measures of disinhibition, positive and negative alcohol expectancies, and drinking. MIMIC modeling, tests of mediation, and tests of moderation were completed to test these relations. It was found that disinhibition and positive alcohol expectancies were each related to drinking in 5th graders. Disinhibition moderated the relation between positive alcohol expectancies and drinking in some cases. Mediation was not supported. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Sex-related alcohol expectancies predict sexual risk behavior among severely and persistently mentally ill adults.

Three hundred three adults (57% male, average age 42 years) with severe and persistent mental illness receiving treatment at community mental health clinics completed a survey, which included B. C. Leigh's (1990) sex-related alcohol expectancy scale and measures of alcohol use and sexual risk behavior. Hierarchical logistic regression analyses, controlling for drinking behavior, revealed that participants with stronger expectancies that drinking would lead to enhanced sexual experience were more likely to have drank prior to intercourse and that, among participants who drank prior to intercourse, those with stronger expectancies that alcohol would lead to riskier sexual behavior were more likely to have engaged in sexual risk behavior. Implications for preventing HIV infection among people with severe mental illness are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Sex-related alcohol expectancies among adolescents: II. Prediction of drinking in social and sexual situations.

Used a measure developed by K. H. Dermen and M. L. Cooper (see record 1995-07934-001) to test the relationship between sex-related alcohol expectancies and drinking in social and sexual situations among a representative sample of 874 sexually experienced adolescents (aged 13–19 yrs) who had ever consumed alcohol. Regression analyses (in which demographics and a global measure of drinking were controlled for) revealed that sex-related alcohol expectancies were better predictors of drinking in sexual situations than were general alcohol expectancies, whereas the reverse was true for drinking in social situations. Different expectancies predicted whether respondents drank in these situations as compared with the frequency of drinking to intoxication in the same situations. Results highlight the value of assessing domain-specific alcohol expectancies when predicting alcohol use in particular situations. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Alcohol-related expectancies versus demographic/background variables in the prediction of adolescent drinking.

The best method currently available for predicting adolescent alcohol consumption is to use the significant relationship that has been found between this variable and demographic/background variables. To assess the theoretical and practical utility of adolescent alcohol expectancies, the present authors pitted these expectancies against important demographic/background variables in the prediction of adolescent drinking. This comparison required 3 procedural steps: (a) factor analytic derivation of 3 adolescent drinking styles, (b) multiple regression prediction of these drinking styles using demographic/background variables, and (c) assessment of the predictive power of alcohol expectancies. Ss were 1,580 12–19 yr olds. Results show that expectancies (as measured by the Alcohol Expectancy Questionnaire for Adolescents) at least equalled and even added to the predictive power of the background variables. Specifically, Ss who drank in a frequent, social manner expected alcohol to enhance their social behavior, whereas Ss who reported alcohol-related problems expected an improvement in their cognitive and motor functioning. Results suggest assessment and treatment strategies for high-risk adolescents and indicate a possible mediator of adolescent drinking problems. (27 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Alcohol-related expectancies: Defined by phase of intoxication and drinking experience.

Assessed common expectancies concerning the effects of alcohol by eliciting expectancy dimensions from 20 undergraduates in a pilot study and then having 253 undergraduates rate the effects they expected from drinking alcohol along these dimensions. Results show that Ss expected moderate drinking (Phase 1) to result in relatively greater stimulation/perceived dominance and pleasurable disinhibition, whereas for heavy drinking they expected a greater degree of behavioral impairment. Stimulation/perceived dominance and pleasurable disinhibition were linearly related to drinking habits for Phase 1 drinking, with heavier drinkers expecting greater stimulation and pleasure. Results suggest that expectancies are important in understanding drinking patterns as well as behavior in drinking situations. (19 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Detection of K-ras point mutations in the supernatants of peritoneal and pleural effusions for diagnosis complementary to cytologic examination

OBJECTIVE: The present study aimed to examine the discriminatory ability of alcohol expectancies and drinking refusal self-efficacy and to identify the differential role of these constructs in social and problem drinkers. METHOD: Drinkers (N = 276) were self-selected from general (n = 185) and clinical (n = 91) populations to complete a 40-minute questionnaire that asked about alcohol expectancies, drinking refusal self-efficacy, consumption, degree of dependence and demographics. RESULTS: The results showed that in social drinkers both the expectancy and self-efficacy constructs were reliably able to discriminate between types of drinker. Expectancy was related to consumption in social drinkers, but did not appear to account for a significant proportion of the variance in problem drinkers. CONCLUSIONS: The findings are discussed in terms of a two-process model of drinking behavior that suggests that expectancies operate differently in social and problem drinkers.