羟胺和苯肼与肉桂酰基Zhuo酚酮的成环反应

羟胺和苯肼作为亲核试剂与３－（３，４，５－三甲氧基）肉桂酰基Ｚｈｏｕ酚酮和３－（３，４－亚甲二氧基）肉桂酰基Ｚｈｏｕ酚酮发生缩合反应分别得到３－（３，４，５－三甲氧基）苯乙烯基异恶唑并［５，４ｂ］Ｚｈｏｕ酮、３－（３，４－亚甲二氧基）苯乙烯基异恶唑并［５，４ｂ］Ｚｈｏｕ酮、３－（３，４，５－三甲氧基）苯乙烯基吡唑并［５，４ｂ］Ｚｈｏｕ酮和３－（３，４－亚甲二氧基）苯乙烯基吡唑并［５，４－ｂ］Ｚｈｏ     

TMB等与乙酰基酚酮缩合反应的研究

本文探讨了酚酮领域内的羟醛结合反应，３－乙酰基酚酮与ＴＭＢ、丁香醛、胡椒醛等取代醛反应分别生成３－（３，４，５－三甲氧基）肉桔酰基酚酮、３－（４－羟基－３，５－二甲氧基）肉桂酰基酚酮和３－（３，４亚甲－３，４－二氧基）肉桂基酚酮．与桂皮醛反应生成３－（５－苯基－２，４－戊二烯酰基）酚酮等四种尚未见文献报道的新化合物．其结构经红外光谱、核磁共振谱及元素分析得以证实．     

3—肉桂酰基Zuo酚酮5位单溴代产物的合成研究

研究了３－肉桂酰基Ｚｕｏ酚酮的５位单溴代产物的合成。设计路线为：以２－肉桂酰基－７－甲氨基基Ｚｕｏ酮（１）为起始原料,首先进行溴化得一４－溴－２－肉桂酰基－７－甲氨基Ｚｕｏ酮（２）;化合物２在氢氧化钠碱性溶液中水解得到目标物５－溴－３－肉桂酰基Ｚｕｏ酚酮（３）,化合物２,３为尚未见文献报道的新化合物,它们的结构经物理性质的测定,光谱数据和元素分析得到证实。     

3－乙酰基酚酮还原新途径的研究

探讨了从３－乙酰基酚酮出发经甲胺基化、还原、水解合成了３－（２－羟乙基）酚酮的新合成路线，使总收率从原来的２０．５％提高到５９．２％。所合成的化合物３为尚未见文献报道的新化合物。其结构已经红外光谱、核磁共振谱及元素分析征实．     

3-肉桂酰基酚酮5位单溴代产物的合成研究

研究了３－肉桂酰基酚酮的５位单溴代产物的合成。设计路线为：以２－肉桂酰基－７－甲氨基酮（１）为起始原料,首先进行溴化得到４－溴－２肉桂酰基－７－甲氨基酮（２）;化合物２在氢氧化钠碱性溶液中水解得到目标物５－溴－３－肉桂酰基酚酮（３）。化合物２、３为尚未见文献报道的新化合物,它们的结构经物理性质的测定、光谱数据和元素分析得到证实。     

3－乙酸基酚酮与芳醛缩合反应的研究

本文探讨了３－乙酰基酚酮与ＴＭＢ等芳香醛的羟醛缩合反应。３－乙酰基酚酮与ＴＭＢ、、丁香醛、胡椒醛等取代醛反应分别生成３－（３，４，５－三甲氧基）肉桂酰基酚酮、３－（４－羟基－３，５－二甲氧基）肉桂酰基酚酮、３－（３，４－亚甲二氧基）肉桂酰基酚酮。与桂皮醛反应生成３－（５－苯基－２，４－戊二烯酰基）酚酮等４种尚未见文献报道的新化合物。其结构经红外光谱、核磁共振谱及元素分析得以证实。     

TMB等与乙酰基Zup酚酮缩合反应的研究

本文探讨了Ｚｕｏ酚酮领域内的羟醛缩合反应，３－乙酰基Ｚｕｏ酚酮与ＴＭＢ、丁香醛、胡椒醛等取代醛反应分别生成３－（３，４，５－三甲氧基）肉桔酰基Ｚｕｏ酚酮、３－（４－羟基－３，５－二甲氧基）肉桂酰基Ｚｕｏ酚酮和３－（３，４－亚甲－３，４－二氧基）肉桂基Ｚｕｏ酚酮。与桂皮醛反应生成３－（５－苯基－２，４－戊二烯酰基）Ｚｕｏ酚酮等四种尚未见文献报道的新化合物。其结构经红外光谱、核磁共振谱及元素分析得以证     

3—乙酰基Zuo酚酮与芳醛缩合反应的研究

本文探讨了３－乙酰基Ｚｕｏ酚酮与ＴＭＢ等芳香醛的羟醛缩合反应。３－乙酰基Ｚｕｏ酚酮与ＴＭＢ、丁香醛戎椒醛等取代醛反应分别生成３－（３，４，５－三甲氧基）肉桂酰基Ｚｕｏ酚酮、３－（４－羟基－３，５－二甲氧基）肉桂酰基Ｚｕｏ酚酮、３－（３，４－亚甲二氧基）肉桂酰基Ｚｕｏ酚酮。与桂皮醛反应生成３－（５－苯基－２，４－戊二烯酰基）Ｚｕｏ酚酮等４种尚未见文献报道的新化合物。其结构经红外光谱、核磁巫振谱及元素     

7''''-O-菊酰基井冈羟胺A的合成

将拟除虫菊酸酰化后,与井冈霉素A的水解产物井冈羟胺A反应,合成了3个未见报道的7'-O-菊酰基井冈羟胺A(4a￣4c),其结构经1HNMR、IR和MS确认。初步的生物活性测试显示,其中4a和4b均表现出一定的杀蚜虫活性,4b对纹枯病菌也表现出一定的抑制作用。     

AMAT的硝化反应及其MNCIO的合成

2－乙酰基－7－甲胺基Zhou酮（AMAT）（1）与硝酸反应，得到2－乙酰基－7－基胺基－4－硝基恶酮（2）。谷物化合物2在碱性条件下水解，得到3－乙酰基－5－硝基Zhou酚酮（3）。化合物3与盐酸羟胺反应，得到3－甲基－5－硝基－8H－环庚并[d]异恶唑－8－酮（MNCIO）（4）。它们的结构均经红外光谱、核磁共振谱得到证实。其中化合物2是未见文献报道的新化合物。     

甲酰基异长叶烯与酮的缩合反应研究

通过甲酰基异长叶烯与酮的缩合反应合成出六种具有香气的新化合物。研究了反应的催化剂,反应位置的选择性和加料方式等因素对反应的影响。所合成出来的化合物均经分离、提纯、分析测试。     

Reactions of dimethoxycarbene with xanthates

Dimethoxycarbene (DMC), generated by thermolysis of 2,2-dimethoxy-5,5-dimethyl–Δ³-1,3,4-oxadiazoline at 110 ^°C, in benzene in a sealed tube, reacted with most xanthates by formal insertion of the carbene into the S=C?SR single bond. The reaction course is probably attack of the carbene at carbon of the C= S function, concomitant with (or followed by) migration of the SR group. The products, all new, are mixed orthoesters (two methoxy and one SR at the same carbon), a functional group that has been reported for one case only. In the case where the R group was CO₂Me, the reaction became complicated, probably from initial attack at the carbonyl group.     

Progress of synthesis and application of hydroxylamine (salts)

简要介绍了生产羟胺（盐）的拉西法、硝酸根离子还原法等工业方法,以及一步合成羟胺的最新研究进展;概述了羟胺（盐）在合成环己酮肟、制备羟胺-O-磺酸等传统应用领域,以及在合成芳香烃胺类、芳香烃酚类化合物等清洁安全化工过程中的最新应用。在此基础上,指出随着羟胺的用途不断扩展,在温和的反应条件下、清洁高效的一步合成羟胺（盐）是今后的研究热点。     

二茂铁丙烯酰羟胺稀土金属配合物的合成与表征

合成了二茂铁丙烯酰羟胺FcCH=CHCONHOH(HL)，并以此为配体与氯化稀土（RECl3)反应，合成了14种稀土金属配合物，通过元素分析，红外光 谱，核磁共振氢谱及紫外光谱对化合物进行了表征。     

Reactions of hydroxyalkyl esters with phenyl isocyanate

In a reaction between 2‐hydroxyethyl methacrylate and phenyl isocyanate (PI), we did not obtain the expected urethane ester monomer but products of its subsequent conversion, namely, ethylene dimethacrylate and ethylene bis(phenylcarbamate). The effects of the structures of various hydroxyalkyl esters on the transformation of the products of their reaction with PI into their respective diesters and alkanediyl bis(phenylcarbamates) were observed with standard spectral methods (IR, ¹H‐NMR) and chromatographic and classical separation techniques. © 2005 Wiley Periodicals, Inc. J Appl Polym Sci 96: 1357–1367, 2005     

硫酸氢钠在催化反应中的应用

介绍了近年来硫酸氢钠在催化酯化和催化缩合反应中的应用 ,指出反应机理研究和开拓其应用领域是今后的研究方向     

Reactions of methylene and ether bridges

The reactions of model compounds containing methylene and ether bridges were examined, in the temperature range 350–400 °C. Aromatic displacement reactions, in which atomic hydrogen displaced the bridges, and homolysis via a keto-enol intermediate were the dominant modes of bridge decomposition. The aromatic displacement reactions of methylene-bridge compounds occurred with activation energies of ≈10 kcal mol^?1 and with A factors of 10^10.5–12 Is^?1 m^?1. The A factors vary with the size of the rings and the substituents on the rings connected by the methylene bridges. The activation energy is relatively independent of these effects. When phenolic substituents are present, methylene bridges can unimolecularly decompose via a keto-enol tautomerism, and the rate of product formation is solvent-dependent. Reactions for ether bridge decomposition were more complex and the rate parameters encompassed a much larger range of values.     

Study on the Reactions of 3-Benzoyl-2,4,5-pyrrolidinetrione with aliphatic diamines,phenylhydrazine, semicarbazide and guanidine derivatives

3-Benzoyl-2,4,5-pyrrolidinetrione ( 1a , b ) with aliphatic diamines, phenylhydrazine, semicarbazide, and guanidine derivatives yields mono and binary salts ( 4 , 7 , 10 , 11 - 14 ), enamines ( 2 , 3 ), imine ( 5 ), pyrrolo[3,4-c]pyrazole ( 6 ) and pyrrolo [3,4-e][1,4]diazepine ( 8 ), respectively. The influence of the reagents basicity on the route of cyclocondensation is studied.