A test of reciprocal inhibition: are anxiety and sexual arousal in women mutually inhibitory?

Tested J. Wolpe's (1958) prediction that autonomic sexual and anxiety arousal states are mutually inhibitory. Using a new physiological measure of female sexual arousal (vaginal blood volume), changes in 7 sexually experienced Ss (mean age 27 yrs) were compared during erotic video stimulation following anxiety and control stimulus preexposure and during anxiety and control stimulation following erotic stimulus preexposure. Consistent with reciprocal inhibition theory, when Ss were sexually aroused by erotic preexposure, anxiety arousal inhibited sexual arousal more rapidly than did an attention control stimulus. However, contrary to reciprocal inhibition theory, Ss became more rapidly aroused sexually following anxiety preexposure than following neutral preexposure. In the case of heart rate, changes were compared during erotic and neutral stimulation following anxiety preexposure and during anxiety arousal following erotic and neutral preexposure. Consistent with the literature to date, there were no heart rate changes that could be attributed to differential preexposure. Taken together, the results do not support Wolpe's reciprocal inhibition theory but do suggest a context interpretation: The way in which sexual and anxiety arousal states interact with each other may depend on the context in which Ss perceive the stimuli that generate these respective arousal states. The clinical implications of the findings are discussed. (27 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Effects of sex guilt, repression, sexual "arousability," and sexual experience on female sexual arousal during erotica and fantasy.

Hypothesized that, among women who were asked to fantasize about sex, erotic preexposure would facilitate arousal during the fantasy, and arousal would be greater among those who had less sex guilt, those who were more arousable, those who were more experienced, and sensitizers. 62 female Ss (aged 18–53 yrs) were randomly assigned to view either an erotic or a nonerotic videotape. All Ss then imagined and wrote out a sexual fantasy. Sexual arousal was measured subjectively by self-report ratings and physiologically by continuous vaginal photoplethysmograph recording. Ss high in sex guilt reported less arousal but showed significantly greater physiological arousal during the erotic videotape than did Ss low in sex guilt. For the high sex-guilt Ss, the erotic videotape facilitated physiological arousal during fantasy. Ss low in sexual arousability and low in sexual experience followed a similar pattern. No significant differences were found for repression-sensitization. Results point toward a pattern of behavioral inhibition that facilitates increased response to forbidden erotica. (36 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Genital and psychoaffective response to erotic stimulation in sexually functional and dysfunctional men.

To understand the sexual response patterns of men with premature ejaculation and erectile dysfunction, the authors compared genital and affective responses of sexually functional and dysfunctional men with 3 types of sexual stimulation: an erotic video, penile vibrotactile stimulation, and a combination of both. Genital response differed across both groups and stimulus conditions, with an interactive effect indicating that groups showed different response patterns depending on the stimulation. Affective responses also differed across groups and interacted with stimulus conditions. The combination genital and affective response was superior to either alone in distinguishing men with no sexual problems from those with erectile or ejaculatory problems (or both). These factors were particularly useful in discriminating men with premature ejaculation from those with combined premature ejaculation and erectile dysfunction. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Expectancies, alcohol, and sexual arousal in women.

A total of 40 university female volunteers, all social drinkers aged 18–35 yrs, were randomly assigned to 1 of 2 expectancy conditions in which they were led to believe that the beverage they were administered contained either vodka and tonic or tonic only. For half the Ss in each expectancy condition, the beverage actually contained vodka; for the other half, tonic only. After their drinks, measures of vaginal pressure pulse obtained with a vaginal photoplethysmograph were recorded during a nonerotic control film and 2 erotic films depicting a heterosexual or a homosexual interaction. The 2 groups that received alcohol, regardless of whether they believed that their drinks contained alcohol, showed significantly reduced sexual arousal during both erotic films. No effects of expectancy or an interaction between alcohol and expectancy were obtained. Ss' subjective estimates of intoxication were significantly correlated with their self-report of sexual arousal during both erotic films. The differences between these results and previous findings using similar procedures with male social drinkers are discussed. (31 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The menstrual cycle and response to erotic literature

133 undergraduate females responded to a pre-experimental questionnaire assessing their contraceptive use (28% on contraceptive pills), sexual experience (71% had had sexual intercourse), and present phase of menstrual cycle. Ss then read an erotic story intended to induce sexual arousal. Results of a self-report postexperimental questionnaire assessing sexual arousal and genital stimulation show no significant response differences based on menstrual cycle phases for Ss not using contraceptive pills. Greatest degree of arousal and sensation was experienced by Ss on contraceptive pills who were in the menstrual phase of the cycle; least arousal and sensation was experienced by Ss on contraceptive pills who were in the premenstrual phase of the cycle. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Effects of alcohol and cognitive set on sexual arousal to deviant stimuli.

48 undergraduate male social drinkers were randomly assigned to 1 of 2 expectancy set conditions in which they were led to believe that the beverage they were administered contained alcohol or no alcohol. For half of the Ss in each expectancy condition, the beverage was an alcoholic malt liquor; the others drank a nonalcoholic malt beverage. After their drinks, changes in penile tumescence (PT) in response to normal and deviant tape recordings and to self-generated fantasy were measured physiologically by a mercury-in-rubber strain gauge. The cognitive set (expectancy) significantly increased PT in response to the various erotic recordings. Alcohol did not significantly influence levels of sexual arousal. Ss who believed they had consumed an alcoholic beverage evidenced significantly more arousal to the forcible rape recording and to the sadistic stimuli than Ss who believed that they had consumed a nonalcoholic beverage, regardless of the actual contents of the beverage. The cognitive set, as well as the alcohol, significantly influenced heart rate, skin temperature, and subjective reports of sexual arousal. Self-report measures of sexual arousal were positively correlated with PT. Mosher Forced-Choice Guilt Inventory scores were not significantly correlated with PT, although the Sex Guilt subscore was negatively correlated with the subjective measure of sexual arousal for the heterosexual intercourse and forcible rape tapes. (35 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The effect of emotional arousal on subsequent sexual arousal in men.

The effect of emotional arousal on subsequent sexual arousal was assessed in 14 18–34 yr old men. Ss initially viewed either 1 of 2 emotionally arousing videotapes (depression-and-anger or anxiety-and-anger producing) or a neutral videotape (a travelogue), each of which was followed by an erotic videotape. Sexual arousal was measured physiologically with a penile strain gauge. Although there were no differences in the level of sexual arousal during the antecedent emotionally arousing or neutral videotapes, sexual arousal during the subsequent erotic videotapes was differentially affected by them. Sexual arousal following the anxiety-and-anger videotape was greater than that following either the depression-and-anger videotape or the travelogue. Prior exposure to the travelogue resulted in greater sexual arousal than did the videotape producing depression and anger. (10 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Self-directed treatment for premature ejaculation.

Tested the effects of self-administered treatment for premature ejaculation vs therapist-administered treatment by assigning 18 couples with premature ejaculation problems to (a) totally self-administered treatment, (b) self-administered treatment in conjunction with minimal therapist (telephone) contact, or (c) standard therapist-administered treatment. All Ss completed the Locke-Wallace Marital Adjustment Test and a sexual background inventory. Ss were successfully treated by therapists or by themselves when they maintained minimal contact with a therapist. Ss working without therapist contact failed to complete treatment successfully. Follow-up data indicate that although there was deterioration in therapeutic gain following the termination of treatment, improvement over pretreatment responses was maintained on all relevant measures. Data also indicate that greatest improvement in ejaculatory control occurred when Ss continued to use the squeeze or pause to delay ejaculation, but significant improvement in latency to ejaculation also occurred when Ss used neither technique to lengthen intercourse. (35 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Females' affective responses to reading erotic literature.

The affective states of sexual arousal, guilt, anxiety, and 11 Nowlis mood factors were studied in 72 college females before and after reading either an erotic or an academically oriented literary passage, with a female E either present or absent, and as a function of the personality disposition of sex guilt. Ss who read the erotic passage showed a significant increase in sexual arousal. High sex guilt Ss significantly increased their affective state of guilt when they read the erotic passage in comparison to the Ss in all of the other cells. Anxiety increased as a function of reading the erotic passage in the presence of E. Conceptual distinctions between sexual behavior and sexual arousal, between guilt as personality disposition and as state, and between affective states of fear and guilt are discussed. (16 ref.) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Differential effects of sympathetic activation on sexual arousal in sexually dysfunctional and functional women.

The effects of sympathetic nervous system (SNS) activation, induced via acute exercise, on sexual arousal in women was studied. In 2 experimental sessions, 36 women viewed a neutral film followed by an erotic film. In 1 session, the women were exposed to 20 min of intense exercise before viewing the films. Twelve women were sexually functional, 12 experienced significant impairments in sexual desire, and 12 experienced primary or secondary anorgasmia. Acute exercise significantly increased vaginal pulse amplitude (VPA) and vaginal blood volume (VBV) responses to an erotic film among sexually functional women and those with low sexual desire. Among anorgasmic women, exercise significantly decreased VPA but had no effect on VBV responses to an erotic film. Acute exercise had no significant effect on the women's perceptions of sexual arousal. Results suggest that increased SNS arousal may affect physiological sexual responding in women. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Treating premature ejaculation in the multi-modal therapeutic framework: a single case study

Generally, premature ejaculation is caused by organic, psychological, interpersonal factors and lay beliefs. It is defined as a lack of adequate voluntary ejaculatory control with the result that a patient climaxes involuntarily. An ejaculatory control may be said to be established when the patient can tolerate high levels of excitement which characterise the plateau stage of the sexual response cycle without ejaculating reflexly. The most effective treatment for premature ejaculation so far is the stop-start exercises that aim to help patients tolerate a prolonged period of intense pleasurable arousal and to enjoy sexual sensation before ejaculation. However, the stop-start exercises would be more effective if they are employed in a multi-modal therapeutic framework. This is because cases of premature ejaculation differ in terms of the aetiology, pathological patterns, and the patients' personal characteristics and background. A case is presented to illustrate how the conventional stop-start exercises are prescribed in this multi-modal framework.     

Sexual behavior in young adulthood: A population-based twin study.

Objective: With behavior genetic analyses of data from young adult twins, we evaluated theoretical perspectives that differentially emphasize biological dispositions, social/cultural factors, or universal pathways to explain individual differences in sexual behaviors. Design: We fit biometric sex limitation models to three aspects of sexual behavior reported by 4,925 Finnish twins ages 23-27. Main Outcome Measure: From a postal questionnaire, we obtained self-report information on initiation/abstinence of sexual intercourse, onset age, and number of sexual partners. Results: Genetic and non-shared environmental influences were significant for all three measures. There were trends for common environmental influences on initiation and, in females, age at first intercourse. Some differential effects in males and females were found. Results comparing onset age and number of partners among experienced twins from pairs concordant and discordant for initiation found genetic and environmental influences on initiation/abstinence overlapped those found for the other aspects of sexual behavior. Conclusions: These results document genetic variation in individual differences in sexual behavior of young adults. Incorporating genetic dispositions into integrated models of sexual behavior will facilitate more effective health promotion and risk taking intervention. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Effects of nicotine fading and relapse prevention on smoking cessation.

In a pilot study, a combined nicotine-fading/relapse-prevention program for 24 smokers (mean age 38.6 yrs) achieved a 46% abstinence rate at 6-mo follow-up. The combined program was then compared to conditions in which 46 smokers (mean age 34.8 yrs) received nicotine fading or relapse prevention only or combination treatment. There was no difference among groups in abstinence or rate at any follow-up point, and overall abstinence levels were only 15% and 9% at 6-mo and 1-yr follow-ups, respectively. Groups receiving nicotine fading tended to retain lower estimated nicotine intake levels. (3 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

A psychometric analysis of the Sexual Arousability Index.

The Sexual Arousability Index (SAI) assesses self-reported sexual arousal in women and was administered on four occasions to a group of normal sexually active women (n?=?57) and to another group undergoing surgical gynecologic treatment (n?=?66) that resulted in a predictable and clinical level of sexual dysfunction. These data were used for a psychometric analysis of the SAI. In terms of reliability, internal consistency estimates were in the .92–.96 range, and 4-month test–retest reliabilities ranged from .74 to .90. An evaluation of validity revealed both strengths and limitations of the SAI. The content analysis indicated that at least six domains are sampled, including seduction activities, body caressing, oral-genital and genital stimulation, intercourse, masturbation, and erotic media. To examine construct validity, we conducted a factor analysis that revealed a five-factor solution accounting for 85% of the variance. Furthermore, the factor solution was stable across groups and time, and the factors were sensitive to the occurrence of important behavior changes. The SAI, like other psychological measures, was poor in predicting a criterion (i.e., the occurrence of inhibited sexual excitement) concurrently or at the time of follow-up. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Effects of alcohol on sexual arousal in women.

During weekly experimental sessions each of 16 university females received in counterbalanced order 4 doses of beverage alcohol prior to viewing a control film and an erotic film. Half of the Ss were instructed beforehand that alcohol would increase their degree of sexual arousal in response to the erotic film; the other half were told that alcohol would decrease their sexual arousal. Measures of vaginal pressure pulse obtained by means of a vaginal photoplethysmograph showed a significant negative linear relation with alcohol doses. A significant Sessions * Instructional Set interaction indicated that Ss in the increase-set condition experienced less sexual arousal. This result is attributed to performance pressure induced by the demand characteristics of the instructional set. Additional measures of sexual arousal, including TAT responses and self-report, showed no differences. With increasing levels of intoxication, however, a greater proportion of Ss reported enhanced sexual arousal. (22 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Sexual function after major resections of the sacrum with bilateral or unilateral sacrifice of sacral nerves

The sexual function of nine patients with severance of sacral nerves bilaterally (five patients) or unilaterally (four patients), performed during operations for radical extirpation of tumors of the sacrum or its vicinity, was studied. Sexual histories were obtained and sensibility tests were performed. In four of the five male patients an attempt was made to collect electromyographic recordings from the external urethral and anal sphincters during ejaculation. Bilateral loss of S3 to S5 nerves in two women seemed not to affect their sexual function. Bilateral loss of S2 to S5 nerves in one man was compatible with gratifying sexual intercourse, the stimulation for erection being purely psychogenic, and "ejaculation" of a dripping nature. Unilateral loss of all sacral nerves did not impair previously normal sexual function, although the penises and vulvae of these patients were anesthetic on one side. The sensibility of the penis seemed to be subserved by the second sacral nerve. The myoelectric activity of the striated urethral and anal sphincters during ejaculation recorded in one patient with unilateral total loss of sacral nerves was normal bilaterally considering the duration of, and intervals between, the clonic contractions.     

Sexual functioning after multimodality treatment for disseminated nonseminomatous testicular germ cell tumor

PURPOSE: We determined sexual functioning after chemotherapy for disseminated nonseminomatous testicular germ cell tumor, and evaluated the impact of resection of post-chemotherapy residual retroperitoneal tumor. MATERIALS AND METHODS: A total of 155 consecutive patients treated with chemotherapy for disseminated nonseminomatous testicular germ cell tumor (between 1980 and 1994) was questioned about their sexual functioning. The patients were divided in 2 subgroups: patients treated with or without resection of post-chemotherapy residual retroperitoneal tumor. Volume and location (divided into left para-aortal or right paracaval/interaortacaval) of the resected tumor were related to absence of ejaculation as well as decreased semen amount. In addition, libido, arousal, erection and orgasm were related to ejaculatory dysfunction. RESULTS: A total of 43 patients (27.7%) was treated with chemotherapy only and 112 (72.3%) had additional resection of post-chemotherapy residual retroperitoneal tumor mass. Overall, 22.4% reported loss of libido, 14.1% decreased arousal, 16% erectile dysfunction, 23.1% decreased orgasmic intensity, 17.4% decreased semen amount and 18.7% complete absence of antegrade ejaculation. With exception of absence of ejaculation, sexual dysfunctions were reported in similar frequencies in both treatment subgroups. In the resection of post-chemotherapy residual retroperitoneal tumor subgroup, 25.9% of the patients had complete absence of ejaculation. The other sexual dysfunctions were related neither to decreased semen amount nor to complete absence of ejaculation. The mean volume of resected tumor was higher (95 cm.3) in patients with absence of ejaculation than in those without (40 cm.3), and patients with right paracaval/interaortacaval tumor (20 of 58, 34.5%) reported more often absence of ejaculation than those with left para-aortal tumor (9 of 54, 16.7%). CONCLUSIONS: In patients treated for disseminated nonseminomatous testicular germ cell tumor, post-chemotherapy sexual morbidity cannot be neglected. Except for loss of antegrade ejaculation, sexual dysfunctions are not related to resection of post-chemotherapy residual retroperitoneal mass. A high volume of tumor and a right paracaval/interaortacaval location predispose to loss of antegrade ejaculation.     

Sex differences in emotional responses to erotic literature.

Compared the effect on male and female undergraduates (n = 112) of reading an erotic passage from a novel; control Ss (n = 112) read a passage from a psychology textbook. Men reported more sexual arousal, interest, and joy in response to the erotic passage, and women reported more disgust. Differences were significant but not large. The sexes did not differ as to fear or guilt reactions. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Phosphofructokinase interacts with molecular chaperonins GroEL and GroES

OBJECTIVE: The present investigation was designed to provide the first empirical examination of the effects of clonidine, a selective alpha 2-adrenergic agonist, on sexual arousal in women with and without prior sympathetic nervous system [SNS] stimulation by exercise. The purpose was to help elucidate the influence of adrenergic mechanisms on sexual function in women. METHODS: Thirty sexually functional women participated in two experimental sessions in which subjective (self-report) and physiological (vaginal photoplethysmograph) sexual responses to erotic stimuli were measured after either clonidine (0.2 mg) or placebo administration in a randomized, double-blind, crossover protocol. Before viewing the experimental films, 15 subjects engaged in 20 minutes of intense exercise designed to elicit significant SNS activation. RESULTS: Clonidine significantly decreased vaginal pulse amplitude, vaginal blood volume, and subjective sexual responses to the erotic films in subjects who were in a state of heightened (via exercise), but not baseline (no exercise) SNS arousal. CONCLUSIONS: Clonidine can significantly inhibit subjective and physiological sexual arousal in women. These findings have implications for deriving an etiological theory of sexual function in women and for understanding the effects of psychotherapeutic drugs on female sexual function.