RESEARCH AND DEVELOPMENT OF BIOCERAMICS(Ⅱ)

The article describes the performance,properties and application of bioceramics in the medicalclinic and reviews and discusses the advance in the researchinto several typical bioceramics,such as aluminium oxidebioceramics,carbons,bioactive glassceramics,calcium phos-phate bioceramics,bioceramic com posite materials etc,andcomes to that bioceramics is the most promising bioactive ma-terial in the modern medical clinic application.     

Experimental Study on Polymer Artificial Bone with HA Coated and Fiber Liners

Layers of ante-polymerized PMMA （ Polymethylmethacrylate ） ore manually smeared on both sides of carbon fiber and polyester fiber to a certain thickness. It was pre-solidified, stripped and cut for sterilization. Based on the results of a series of experiments, HA coated artificial bone is considered to be a non-senshizing, non- irritant, and non- toxic biomaterial for medical applications. The artificial bone has excellent mechanical and biological property. And it conforms to the national standard requirement. Safety analysis guarantees h a prosperous future of clinical application.     

Biological analysis of woodpecker’s brain after impact experiments

Woodpeckers can withstand a fierce impact during pecking. Previous studies have focused on the biomechanical analysis of the pecking process, the properties of the beak and hyoid bone of woodpecker; however, the biological characteristics of the woodpecker brain are also important in resisting impact injuries. We employed impact experiments and biological analysis in normal and injured brains to reveal the impact-resistant biological characteristics of woodpecker brains, as well as the impact energy's biological effects on the woodpecker brain. The hoopoe, which has a similar size but only a slight pecking behavior, was selected as the control group to compare brain morphology and neuronal cells differences in normal brains between woodpecker and hoopoe by sectioning and staining. A loading device was designed to conduct a quantifiable impact energy to the woodpeckers' head. Four groups of woodpeckers were impacted with the same energy on the forehead, beak, tempus and occiput,respectively. Biological changes in the injured brains were evaluated by Nissl staining and enzyme-linked immunosorbent assay.The results showed that:(1) woodpeckers had a larger cerebellum and a higher density of Nissl bodies than hoopoe;(2) Nissl apoptosis appeared in the brain samples after the forehead and the occiput impact experiments, but no obvious Nissl body apoptosis was observed after impact on the tempus and the beak;(3) β-amyloid protein accumulated in the normal status woodpecker brain. This study reveals that: woodpecker brain morphology is well-adapted to impact, woodpecker heads display location-dependent protective performance, with beak and tempus regions having a better protective performance than the forehead and occiput, Nissl apoptosis appears in injured woodpecker brains, and that the accumulation of β-amyloid protein does not show a direct relationship with the injury state of woodpecker's brain tissue in our study.     

Preface

<正>Fibers have been closely related to the human civilization ever since the origin of mankind. As they evolved from natural fibers such as cotton, hemp, silk and wool which are widely used on the daily basis, to the synthetic fibers with designated properties and high performance targeted for aerospace and military usage, fibers are even more closely connected to human society than ever. Nowadays, with the integration of physics, chemistry, biology, medical science, and information technology, fiber science     

Pilot study on combined process of catalytic ozonation and biological activated carbon for organic pollutants removal

A combined process of catalytic ozonation in the presence of a novel heterogeneous catalyst and biological activated carbon was investigated for the removal of priority control organic pollutants, the reduction of genotoxicity, and the improvement of biodegradable dissolved organic carbon (BDOC). Results confirm that the catalytic ozonation has higher effectiveness for the removal of refractory harmful organic pollutants, the reduction of genotoxicity and the increase of bio-degradability of organics than ozonation alone, which results in lower pollution load for subsequent biological activated carbon process, and then leads to less organic pollutants penetrating biological activated carbon. The novel catalytic ozonation with this combined process exhibits excellent performance to guarantee the safety of drinking water.     

Influence of Rubber Powder Movement on Properties of Asphalt Rubber from the Mesoscopic View

The research on asphalt performance mainly focused on the macro performance and micro mechanism. Mesoscopic analysis was introduced to study the effect of rubber powder movement on asphalt rubber properties. After the preparation parameters and the preparation process of asphalt rubber were determined, the modification mechanism and rheological properties were analyzed which revealed the compatible stability mechanism. Then, the analysis model of asphalt rubber was established to focus on simula...     

Study on Model for Assessmentof Quality Management Performance of Coal Preparation Plant in CIMS

In this paper the method to calculate intangible quality cost is put forward for the first time based on the production and management characteristics of coal preparaticn plant. A model for assessment of quality manage ment performance of coal preparation plant is established on the ground of quality cost. By using of CIMS integration environment the strategy to carry out the model and the applieation example are also offered. It provides a new and feasible way to assess performance quality management of coal preparation plant.     

Bionic surface design of cemented carbide drill bit

The development of a high-performance cemented carbide drill bit is of great significance to the reduction of rock drilling-cost. The non-smooth features of a biological surface provide an insight into how they can obtain low friction and good wear resistance with evolving surface morphology. By analyzing the mechanism of the surface of a dung beetle for reducing soil wear and adherence, we design a cemented carbide drill bit with a bionic surface, which is expected to have superior anti-wearing and anti-sticking properties for drilling the soft coal seam. Inspired from the characteristics of the head and pronotum surface of the dung beetle, optimized non-smooth surface of the drill bit was constructed. The working performance of this innovative drill was experimentally tested. With comparative experiments under the identical drilling conditions, the wear rates, drilling times of conventional drills and bionic drills were measured. Compared with the conventional counterpart, the drill designed exhibits better performance in reducing wear and sticking drilling-breaks, therefore achieving higher levels of efficiency. The diameter of the dome and pit on the bit surface is in the range of 0.8–1.2 mm, and the bionic drill bits could get better performance with preferable drilling speeds and wear rates.     

Effect of drawbead on forming performance of subsequent sheet

In order to research the plastic performance of sheet going through the drawbead and the simple tensile test of sheet, the influence of drawbead structure parameters on sheet performance and the subsequent performance of the sheet were performed to investigate the residual deformation characteristics of the sheet through different drawbead structures, and also the influences of drawbead structures and geometry parameters on pre-deformation and subsequent forming characters of sheet were analyzed. The results show that the pre-deformation decreases with the increase of the round corner radius, the pre-deformation increase with the increase of the height of drawbead, and the subsequent forming characteristics of sheet going through drawbead are remarkably different from undeformed sheet and these differences heavily depend on the pre-deformation. With the increases of pre-deformation, the yield ratio increases, but the subsequent elongation exponential decreases. These means deformability of the sheet is significantly reduced. As the structure of drawbead changes, the mechanical characteristics of material in different cyclic loading conditions also change. For the BUFDE+Z deep drawing steel sheet, the subsequent performance of the sheet is hardened when the pre-deformation is greater than 0.044. For the DC52D+ZF hot-galvanize steel sheet, the subsequent performance of the sheet begins to harden when the pre-deformation is greater than 0.079, and it presents that the pre-deformation is not bigger than 0.052.     

生物陶瓷材料的生物学性能评价

生物学性能评价是生物陶瓷材料研究中的重要部分，本文论述了生物学性能评价的发展和它在生物医学材料研究开发中的作用，并在分析和研究国际先进国家标准的基础上，提出了生物陶瓷材料生物学性能评价的试验项目和试验方法，从而保证我们所研究的生物陶瓷材料在临床应用中的安全性。     

用于大段骨缺损修复的TCP／HA基多孔生物陶瓷的研制

探索了ＴＣＰ／ＨＡ基多孔生物陶瓷的配料组成，确定了较优制备条件，并通过Ｘ－射线衍射分析及ＳＥＭ等揭示了材料的矿物组成及显微结构。制备出有望用于临床的多孔生物陶瓷材料     

利福平壳聚糖蛋白微球的制备及性能研究

选择生物相容性好,可生物降解的壳聚糖蛋白为药物载体,并测定了微球粒径,药物组分含量及载体自身结构和释药过程等主要物理性能,考察了制备工艺中的W/O型分散体系程度、投药量等物理量对形态、粒度、分布和体外降解等的作用.结果表明自制的利福平壳聚糖蛋白微球符合临床使用要求,可作为新型缓释药物临床应用.     

利福平壳聚糖的制备及性能研究

选择生物相容性好，可生物降解的壳聚糖为药物载体，并通过体外释放试验和体外抗菌试验，从载体的自身结构和释药过程的两个方面，对其结构进行了测定和分析。结果表明，所合成的利福平壳聚糖体系；具有一定缓释性能，符合临床使用要求，可作为新型缓释药物临床应用。     

小波分析方法在医学图像融合中的应用

在临床的实际应用中,单模态的医学图像(CT,MRI)的3D重建不能提供医生所需要的足够信息. 由于成像机理不同和人体组织结构的高度复杂性,不同模态的医学图像提供了不互相覆盖的结构互补信息. 为此在医学图像配准的基础上提出基于小波变换的最大值融合规则,局部平均梯度融合规则,区域能量融合规则等算法. 通过对CT图像与MRI图像基于小波变换的不同融合规则及融合算子进行融合的实验结果比较表明,以区域能量融合规则作为准则的融合效果更好. 能够把这两种图像优点结合在一张图像上,这样能为病变提供准确的定位参照,能清晰地显示病变自身,对诊断和治疗更加有利.     

TCP－HA－BG多孔复合生物陶瓷降解性能研究

从物理化学、物质结构、热力学、断裂力学等观点出发，远用原子吸收光谱电子计算机图象分析仪等手段，考察了该系统复合陶瓷的体外静、动态溶解性能及动物体内降解性能，分析了影响材料降解能力的各种内在及外界因素。得出材料的降解机理主要是液体介导过程。     

关于加强高校保健工作的探讨

随着医学模式的转化，为了保护人才，对高级知识分子的身体保健是高校医务人员义不容辞的责任．本文从卫生、医疗、心理等不同保健内容提出以下建议：加强保健教育；开展心理咨询，重视师生员工的心理卫生；加强病例档案管理；加强卫生监督，提高医务人员医院外抢救水平．     

现代医学模式与医德在医疗中的作用论谈

传统的以“疾病为中心”的纯生物医学模式，因存在局限性，已不适应现代医疗卫生事业的发展．随着医学领域的逐渐开拓，新的以“病人为中心”的现代医学模式已形成，新的现代医学模式强调人类疾病的产生与生物、心理、社会、环境因素原因有直接关系．在现代医学模式理论形成的同时，医德医风建设是衡量医疗卫生领域工作的重要内容，是医务人员职业道德与社会关系的行为准则．     

The Bisphosphonate Clodronate Modifying Hydroxyapatite Bioceramics for Bone Scaffold

To investigate the efficiency of clodronate modifying HA bioceramics,and to evaluate the effect of clodronate modifying HA bioceramics on the cells in vitro,clodronate modified the porous HA bioceramics for bone scaffold by chelation .The outermost layer of the specimens was analyzd by XPS and FI-IR ,The depth profile was investigated by the argon-ion sputtering method.The cell culture test was conducted using MC3T3-E1 osteoblastic cells,The cells were inoculated and cultured on the scaffolds.Morphological observation of the cells,MTT test and ALP activity test evaluated the cell attachment ,proliferation and activity on the scaffolds.The cell culture test in cell quantity and morphology indicated active proliferation of the cells on the scaffolds.The ALP activity of the cells cultured for 3d and 7d on clodronate-HA bioceramics was slightly higher than that on HA bioceramics ,but the difference was not signifcant,This result indicated that clodronate-HA bioeramics had favorable cytocompatibility to be used as bone scaffold with potential ability to improve asteogensis.