共查询到20条相似文献,搜索用时 167 毫秒
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以D-氨基葡萄糖盐酸盐与对甲氧基苯甲醛、对甲基苯甲醛反应合成了两种新的D-氨基葡萄糖席夫碱(对甲氧基苯甲醛缩D-氨基葡萄糖席夫碱、对甲基苯甲醛缩D-氨基葡萄糖席夫碱),收率分别为67.9%、74.6%。使用UV1、HNMR和IR对产物进行了结构表征。测试了两种席夫碱甲醇饱和溶液对香蕉炭疽病菌、芒果炭疽病菌、芒果蒂腐病菌、芒果焦腐病菌、番木瓜炭疽病菌等植物病原真菌的抑菌性能。结果表明,对甲氧基苯甲醛缩D-氨基葡萄糖席夫碱对香蕉炭疽病菌、芒果蒂腐病菌、芒果焦腐病菌具有很强的抑菌活性,对甲基苯甲醛缩D-氨基葡萄糖席夫碱对香蕉炭疽病菌、芒果炭疽病菌具有很强的抑菌活性。 相似文献
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The inhibiting action of 4-amino-antipyrine (AAP) and its schiff bases 4-[(benzylidene)-amino]-antipyrine (BAAP), 4-[(4-hydroxy
benzylidene)-amino]-antipyrine (SAAP) and 4-[(4-methoxy benzylidene)-amino]-antipyrine (AAAP) which are derived from 4-amino-antipyrine
with benzaldehyde, salicylaldehyde and anisaldehyde, toward the corrosion behavior of mild steel in 1 M HCl solution was studied
using weight loss, potentiodynamic polarization, electrochemical impedance and FT-IR spectroscopic techniques. Although AAP
was found to retard the corrosion rate of mild steel, the synthesized schiff base compounds were seen to retard the corrosion
rate very effectively. The inhibitor efficiencies calculated from all the applied methods were in good agreement and were
found to be in the order: AAAP > SAAP > BAAP > AAP. 相似文献
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设计、合成吲哚席夫碱类衍生物并研究其抗HIV-1活性。以3-吲哚甲醛衍生物为原料,在碱催化下与芳香胺发生缩合反应合成吲哚席夫碱类化合物,并采用通过 MTT 法测试了目标化合物在MT-4 细胞内的抗 HIV-1病毒株的活性。 合成了32个吲哚席夫碱类衍生物,其结构均通过1H NMR和MS加以确证。初步的生物活性结果测试表明,所合成的吲哚席夫碱类化合物对HIV-1均有优秀的抑制活性,并具有广谱的抗HIV-1活性。其中化合物31 (EC50 = 0.06 mol/L)展现出了最强的抗HIV-1活性,与阳性药物地拉韦啶 (DLV, EC50 = 0.57 mol/L)相当;同时,化合物31具有非常低的毒性,选择指数 (SI)高达2500,明显高于地拉韦啶 (DLV, SI = 1272.9)和依法韦仑 (EFV, SI = 321)。将吲哚和席夫碱两个药效团,能够得到高效、低毒的HIV-1逆转录酶抑制剂,为今后发展新型的HIV-1抑制剂提供了新思路。 相似文献
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酰腙类化合物是由酰肼与醛或酮缩合而成的一类Schiff碱类化合物,具有独特的生物活性和较强的的抑菌、抗病毒和抗肿瘤的生物活性。本文以甲基丙烯酸甲酯、乙酰乙酸乙酯为反应物,分别与水合肼反应,生成了甲基丙烯酰肼与二乙酰肼,进一步缩合,得到未见报道的环戊酮甲基丙烯酰腙和丙酮二乙酰腙。 相似文献
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Hydroxyapatite (HAp) has prospective applications in the field of biomaterials as it has good biocompatibility and mechanical reliability. HAp has been synthesized using surfactants and organic modifiers, which follow the mechanism of chelating the calcium and phosphate precursors to form the calcium phosphate mineral mimicking the mineral in native human bone. The method followed in this work exploits schiff’s base which follows the same mechanism of chelating the reactants necessary for HAp formation. Needle-like nanostructures were formed in the presence of the schiff’s base derived from salicylaldehyde and 1, 4-diaminobutane. The synthesized schiff’s base and HAp were characterized using FT-NMR, XRD and FT-IR to confirm their chemical structure and crystallinity. The cytotoxic evaluation of the synthesized HAp was performed using MTT assay with murine fibroblast (L929) cells, which proved the proliferation activity of the cells in presence of HAp was found to be directly proportional to the time of exposure and HAp concentration, hence, inferring that the synthesized HAp is not only biocompatible but also promotes cell proliferation. 相似文献
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根据α,β-不饱和醛酮亲核加成反应原理合成化合物L{[3-(4-N,N-dimethyl-pyenyl)-5-Anthracen-9-yl]-Pyrazoline}和化合物M[3-ferroceny-5-(Anthracen-9-yl)-Pyrazoline]。利用~1H NMR和~(13)C NMR对化合物进行结构表征,通过抑菌实验研究化合物抑菌生物活性。探析新型吡唑啉衍生物对革兰氏阳性菌、革兰氏阴性菌和真菌的抑菌效果,研究其结构变化对活性的影响。结果表明,化合物L和M对典型革兰氏阳性菌和典型革兰氏阴性菌有一定的抑菌效果,对真核细胞型微生物作用不明显。通过比较两者对细菌的作用结果(抑菌圈直径的大小),化合物L的抑菌作用明显强于化合物M,化合物L吡唑啉环连接N、N-二甲基苯环可能增强了抑菌生物活性。 相似文献
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以水杨醛和2,2-二氨基二苯二硫醚反应,合成了含有芳香二硫键的席夫碱,将合成的席夫碱和聚四氢呋喃醚二醇、异佛尔酮二异氰酸酯、2,2-二羟甲基丁酸和1,4-丁二醇反应,制备了席夫碱自愈合水性聚氨酯。通过1HNMR、FTIR、对合成的席夫碱和聚氨酯进行表征,结果表明合成了有芳香席夫碱和芳香二硫键的自愈合水性聚氨酯;通过划痕测试和愈合测试对聚氨酯自愈合能力进行了表征,结果表明,SWPU-2的划痕愈合效果和自愈率都是最佳,在室温下愈合12h后,SWPU-2划痕消失,室温下愈合24h后,聚氨酯的自愈率可以达到95.8% 相似文献
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新型视黄基席夫碱盐的合成与吸波性能研究 总被引:1,自引:0,他引:1
以维生素A乙酸酯为原料,通过水解、活性二氧化锰氧化得视黄醛,醛与联苯胺反应合成席夫碱,席夫碱掺杂金属银化合物制得新型视黄基席夫碱盐。研究了活性二氧化锰氧化试剂对产物产率的影响,并通过元素分析、红外光谱等对产物结构进行了表征。结果表明,以活性二氧化锰为氧化剂,在常温下氧化反应26 h;合成视黄基席夫碱银盐的条件为80℃,反应4 h;在2~18 GHz范围内测定掺杂银盐的吸波性能,最好的反射率为~16 dB。 相似文献
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《国际聚合物材料杂志》2012,61(4):489-499
Abstract Novel poly(schiff reagent)s (PSs) from diketo derivative of epoxy resin were synthesised and characterised. A series of epoxy resin based poly(schiff reagent)s were synthesised by reacting an epoxy resin, diglycidyl ether of bisphenol-A (DGEBA) with 4-amino acetophenone (4-AAP) in a 1:2 mole ratio to afford the corresponding diketo derivative, and subsequent reaction with various aliphatic diamines in the presence of a triethyl amine as a catalyst The resultant poly(schiff reagent)s were characterised by infrared spectroscopy (IR) and number average molecular weight (Mn) of PSs were estimated by non-aqueous conductometric titration. As produced, PSs having amine groups may act for curing of epoxy resins. Differential scanning calorimetric (DSC) curing kinetics of the epoxy resins viz., diglycidyl ether of bisphenol-A(DGEBA) and triglycidyl-p-amino phenol (TGPAP) have been investigated using PSs as a curing agent and triethyl amine as a catalyst. Thermal stability of the cured epoxy systems was studied by thermo-gravimetric analysis (TGA). The glass fiber reinforced composites of the produced PSs-epoxy system have been fabricated and were characterised by their mechanical properties and chemical resistance. 相似文献
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《国际聚合物材料杂志》2012,61(3-4):499-509
Abstract Novel poly(schiff reagent)s from diketo derivative of epoxy resin were synthesised and characterised. A series of epoxy resin based poly(schiff reagent)s were synthesised by reacting an epoxy resin, diglycidyl ether of bisphenol-A (DGEBA) with 4-amino acetophenone (4-AAP) in a 1:2 mole ratio to afford the corresponding diketo derivative, and subsequent reaction with various aliphatic diamines in a presence of a triethyl amino as a catalyst. The resultant poly(schiff reagent)s were characterised by infrared spectroscopy (IR) and number average molecular weight (Mn) of PSs were estimated by non-aqueous conductometric titration. As produced, PSs having amine groups may act for curing of epoxy resins. Differential scanning calorimetric (DSC) curing kinetics of the epoxy resins viz. diglycidyl ether of bisphenol-A(DGEBA) and triglytidyl-p-amino phenol (TGPAP) have been investigated using PSs as a curing agent and triethyl amine as a catalyst. Thermal stability of the cured epoxy systems were studied by thermogravimetric analysis (TGA). The glass fiber reinforced composites of the produced PSs-epoxy system have been fabricated and were characterised by their mechanical properties and chemical resistance. 相似文献