共查询到20条相似文献,搜索用时 46 毫秒
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Concerns regarding bacteria in runoff entering Santa Monica Bay were validated by the isolation of human enteric virus in storm drain effluents. As an alternative to chlorination, ozonation was investigated for disinfection of dry-weather urban runoff. Ozone at 10-20 mg/L reduced coliform counts an average of 3.4-logs, with 6-log maximal disinfection. Although varying contaminant concentrations complicate the analyses, total organic carbon predicted ozone demand, and effluent coliform counts were correlated with ozone residuals. 相似文献
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Olga Kalinina Alexey Golovkin Ekaterina Zaikova Arthur Aquino Vadim Bezrukikh Olesya Melnik Elena Vasilieva Tatiana Karonova Igor Kudryavtsev Evgeny Shlyakhto 《International journal of molecular sciences》2022,23(16)
Hypercytokinemia, found in SARS-CoV-2 infection, contributes to multiple organ dysfunctions with acute respiratory distress syndrome, shock etc. The aim of this study was to describe cytokine storm signatures in patients with acute COVID-19 and to investigate their influence on severity of the infection. Plasma levels of 47 cytokines were investigated in 73 patients with moderate and severe COVID-19 (41 and 32, respectively) and 11 healthy donors (HD). The most elevated levels comparing patients and the HD were observed for seven pro-inflammatory cytokines (IL-6, IL-8, IL-15, IL-18, IL-27, IFNγ, TNFα), three chemokines (GROα, IP-10, MIG), two anti-inflammatory cytokines (IL-1RA, IL-10), and two growth factors (G-CSF, M-CSF). The patients with severe disease had significantly higher levels of FGF-2/FGF-basic, IL-1β, and IL-7 compared to the HD. The two groups of patients differed from each other only based on the levels of EGF, eotaxin, and IL-12 p40. Pneumonia lung injury, characterized by computer tomography, positively correlated with levels of EGF, IP-10, MCP-3 levels and negatively with IL-12 p40. Pro-inflammatory factors including IL-6, TNFα, and IP-10 negatively correlated with the frequency of the circulating T-helper17-like cells (Th17-like) and follicular Th cells that are crucial to develop SARS-CoV-2-specific plasma cells and memory B cells. Obtained data on the cytokine levels illustrate their influence on progression and severity of COVID-19. 相似文献
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Giulio Verna Marina Liso Elisabetta Cavalcanti Giusy Bianco Veronica Di Sarno Angelo Santino Pietro Campiglia Marcello Chieppa 《International journal of molecular sciences》2021,22(15)
Dendritic cells (DCs) can be divided by lineage into myeloid dendritic cells (mDCs) and plasmacytoid dendritic cells (pDCs). They both are present in mucosal tissues and regulate the immune response by secreting chemokines and cytokines. Inflammatory bowel diseases (IBDs) are characterized by a leaky intestinal barrier and the consequent translocation of bacterial lipopolysaccharide (LPS) to the basolateral side. This results in DCs activation, but the response of pDCs is still poorly characterized. In the present study, we compared mDCs and pDCs responses to LPS administration. We present a broad panel of DCs secreted factors, including cytokines, chemokines, and growth factors. Our recent studies demonstrated the anti-inflammatory effects of quercetin administration, but to date, there is no evidence about quercetin’s effects on pDCs. The results of the present study demonstrate that pDCs can respond to LPS and that quercetin exposure modulates soluble factors release through the same molecular pathway used by mDCs (Slpi, Hmox1, and AP-1). 相似文献
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《明肢科学与技术》创刊于1981年9月,走过了26年的风雨历程,到2006年岁末整整地出版了100期。这是中国明胶历史上的一件大事,在中国明胶历史上写下了闪光的一页。 相似文献
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针对城市放江雨水中微污染物的特征及风险控制需要,本文利用色谱-串联质谱法分析了上海市中心城区某雨水收集排放系统中挥发性有机微污染物及四大类抗生素(磺胺类、喹诺酮类、四环素类、大环内酯类)的赋存特征,并对其中的三种典型微污染物,采用生态风险模型评估了其对受纳水体的生态风险。结果显示:该雨水排放系统中共检测出129种挥发性有机微污染物及6种抗生素,其中邻苯二甲酸二丁酯、双酚A和氧氟沙星这三种典型微污染物对受纳水体均存在不同程度的生态风险,鉴于此,本文提出了从源头削减、过程控制及末端处理三方面的微污染物阻断措施,以期为降低微污染物入河生态风险、保障城市水环境生态安全提供参考和借鉴。 相似文献