阿魏酸稀土配合物的合成及抗凝血性能研究

采用溶剂热法,以阿魏酸与稀土氯化物RECl3·6H2O(RE=Nd3+、Ce3+、Eu3+)为原料在乙醇溶液中合成阿魏酸稀土配合物.采用傅立叶红外光谱分析、紫外可见吸收光谱分析、差热—热重分析等对配合物进行了表征,推测其结构为(C10H9O4)3RE·3H2O.同时对配体阿魏酸及其配合物的抗凝血性能进行了比较,结果发现...     

柠檬酸-邻菲啰啉-稀土三元配合物的合成与表征

在无水乙醇溶液中,以邻菲啰啉(Phen)、柠檬酸(H3Cit)为配体,合成了7种稀土三元固体配合物.通过元素分析、摩尔电导率测定、红外光谱和热重差热分析等手段确定配合物的组成为RE(Cit)·Phen·2H2O(RE=La3+,Pr3+,Nd3+,Sm3+, Eu3+,Tb3+,Dy3+).     

钐、镝-2-噻吩甲酸-2,2'-联吡啶三元配合物的合成及Dy3+的荧光性质研究

合成了钐、镝与2-噻吩甲酸-2,2'-联吡啶的三元配合物.通过元素分析、稀土配合滴定及TG-DTG分析,确定了配合物组成为:REL3L'·C2H5OH(RE=Sm,Dy;L=2-噻吩甲酸,L'=2,2'-联吡啶);摩尔电导数据表明,此配合物为非电解质;测定了配体及配合物的红外光谱,表明配体2-噻吩甲酸中的羧基氧与稀土离子配位,2,2'-联吡啶上两个氮原子与稀土离子配位.还研究了Dy3 配合物的荧光激发和发射光谱.     

掺杂铽的稀土酒石酸配合物的合成及其荧光性能研究

采用溶液反应法合成了掺杂铽的稀土酒石酸配合物Ln2 -xTbxL3(Ln =Y、La、Gd) ,通过元素分析、X射线粉末衍射及红外光谱等对其组成进行了表征 ,测定了该系列配合物的荧光光谱。实验结果表明 ,该系列配合物的组成为Ln2 -xTbxL3·6H2 O(Ln =Y、La、Gd) ,该掺杂配合物比单纯配合物Tb2 L3 具有更好的发光性能 ,而且当x =0 .7～ 1.5时 ,该掺杂配合物的发光最强。据此探讨同多核稀土酒石酸配合物及杂多核稀土酒石酸配合物发光机理     

2,6-二乙酰基吡啶缩合苯磺酰肼铕配合物的合成及性质研究

合成了2,6-二乙酰基吡啶-苯磺酰肼Schiff碱(DAPBSH)及其与稀土Eu3+的配合物,采用元素分析、红外、核磁等表征手段确定了配体的结构,采用元素分析及热分析初步确定了配合物的结构Eu(DAPBSH)2(NO3)3·2H2O并对配合物的紫外、荧光性质做了初步研究。     

稀土-间苯二甲酸-乙酰丙酮三元配合物的合成及发光性能EI北大核心CSCD

在乙醇体系中,由双配体间苯二甲酸(H_(2)PIA)和乙酰丙酮(Hacac)与稀土硝酸盐反应合成了相应的4种稀土三元配合物[Ln_(2)(PIA)_(2)(acac)_(2)](Ln=Sm(1),Eu(2),Tb(3),Dy(4)),用元素分析、红外光谱、热重分析进行表征,并推断了其可能的结构.为便于比较三元配合物的发光性能,同时也制备了相应的稀土间苯二甲酸[Ln2(PIA)3(H_(2)O)_(4)]和稀土乙酰丙酮二元配合物[Ln(acac)_(3)(H_(2)O)].室温下,测定了三元和二元配合物的荧光光谱,结果表明,所有配合物均显示稀土中心离子特有的发射,三元配合物的发光强度好于二元配合物(除了镝配合物),说明双配体对中心离子有协同敏化作用,其实验结果用配体最低三重态能级T_(1)(来自Gauss理论计算)与中心金属离子最低激发态能级的匹配情况予以解释.     

稀土-蛋氨酸-邻菲咯啉配合物的合成、表征及抗菌活性研究

采用冷凝回流法合成了4种新型稀土(镧、铕、钐和钕)-蛋氨酸-邻菲咯啉三元配合物,通过元素分析、EDTA-滴定、摩尔电导、红外光谱,确定了配合物的组成为RE(Met)_3phenCl_3·3H_2O(RE:La~(3+)、Eu~(3+)、Sm~(3+)、Nd~(3+);Met=L-蛋氨酸;phen=邻菲咯啉).抗菌活性的研究表明,与配体相比,稀土三元配合物对大肠杆菌(Escherichia coli)和金黄色葡萄球菌(Staphylococcus aureus)均具有更强的抑菌能力.     

稀土配合物[Ln(C_3H_7NO_2)_x(C_3H_4N_2)(H_2O)](ClO_4)_3(Ln=La,x=3;Ln=Pr,Nd,Sm,x=2)的合成、表征与热分析

合成了稀土高氯酸盐与咪唑、DL α 丙氨酸的4种配合物晶体。经傅里叶变换红外光谱(FTIR)、元素分析和化学分析测定后确定其组成为[Ln(C3H7NO2)x(C3H4N2)(H2O)](ClO4)3(Ln=La,x=3;Ln=Pr,Nd,Sm,x=2)。用差示扫描量热法(DSC)测定了4种配合物的热分解数据,4个配合物开始熔化分解的温度分别为502 5K,532 4K,495 7K,516 7K,配合物有较高的热稳定性。     

稀土–间苯二甲酸–乙酰丙酮三元配合物的合成及发光性能（英文）

在乙醇体系中,由双配体间苯二甲酸(H_2PIA)和乙酰丙酮(Hacac)与稀土硝酸盐反应合成了相应的4种稀土三元配合物[Ln_2(PIA)_2(acac)_2](Ln=Sm (1),Eu (2),Tb (3),Dy (4)),用元素分析、红外光谱、热重分析进行表征,并推断了其可能的结构。为便于比较三元配合物的发光性能,同时也制备了相应的稀土间苯二甲酸[Ln_2(PIA)_3(H_2O)_4]和稀土乙酰丙酮二元配合物[Ln(acac)_3(H_2O)]。室温下,测定了三元和二元配合物的荧光光谱,结果表明,所有配合物均显示稀土中心离子特有的发射,三元配合物的发光强度好于二元配合物(除了镝配合物),说明双配体对中心离子有协同敏化作用,其实验结果用配体最低三重态能级T_(1 )(来自Gauss理论计算)与中心金属离子最低激发态能级的匹配情况予以解释。     

铕-苯并二氢吡喃酮类配合物的合成与荧光性质

合成了3-苯甲酰基-2-庚基苯并二氢吡喃-4-酮(L_1)、3-苯甲酰基-2-苯基苯并二氢吡喃-4-酮(L_2) 2种配体。分别以L_1和L_2为第1配体,水为第2配体在溶剂乙醇中与EuCl_3反应(pH=7～8),合成了2种新的稀土配合物。运用元素分析、红外光谱、荧光光谱、热重分析和扫描电子显微镜对相关物质进行了表征。结果表明:2种配合物的组成分别为Eu(L_1)_3·2H_2O和Eu(L_2)_3·2H_2O;荧光光谱表明,2种配合物都能发出很强的铕离子特征荧光,其中配合物Eu(L_2)_3·2H_2O的荧光强度更强,具有更好的荧光性能。     

纳米均苯三甲酸铽配合物的合成及荧光性质

本文以聚乙烯吡咯烷酮为表面活性剂,在水溶液中合成了纳米均苯三甲酸铽配合物.并通过红外光谱、透射电镜、荧光光谱等表征手段对其进行了表征.结果表明,纳米均苯三甲酸铽的荧光光谱在主要发射峰的峰位、峰强、半高宽和最强峰与次强峰的强度之比等方面与普通均苯三甲酸铽有明显差别.     

稀土三元配合物的合成、表征及其抗菌活性研究

以稀土氯化物、联咪唑和噻吩甲酰三氟丙酮为原料制备了一系列新型稀土三元配合物Ln(TTA)3L(Ln=Nd3+,Eu3+,Er3+;TTA=噻吩甲酰三氟丙酮;L=联咪唑),抗菌实验结果显示,三元配合物抑菌圈直径为12～17 mm,对大肠杆菌、金黄色葡萄球菌具有一定的抑制作用,且对大肠杆菌的抑制效果较好。     

Study on macromolecular lanthanide complexes (V): Synthesis,characterization, and fluorescence properties of lanthanide complexes with the copolymers of styrene and acrylic acid

In this study, the luminescent macromolecular lanthanide complexes Ln‐PSt/AA (Ln = Eu and Tb; St = styrene; AA = acrylic acid) have been synthesized, and an extensive characterization has been carried out by means of elemental analysis, FTIR, thermal analysis, and fluorescence determination. The results showed that the carboxylic groups on the chain of the polymers acted as bidentate ligands coordinated to lanthanide ions; and the coordination degree of ? COO^?/Ln³⁺ in the macromolecular complexes was closely dependent on both the pH value of the solution and the molar ratio of St to AA in the polymeric ligands. Thermal analysis manifested that these Ln‐PSt/AA (Ln = Eu and Tb) complexes had high thermal stability and solvent resistance, and these macromolecular complexes were highly crosslinked. The fluorescence determination indicated that Ln‐PSt/AA complexes could emit characteristic fluorescence with comparatively high brightness and good monochromaticity, and the fluorescence intensity changed with increasing lanthanide ions content. © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2009     

Mitochondrial Fragmentation Is an Important Cellular Event Induced by Ruthenium(II) Polypyridyl Complexes in Osteosarcoma Cells

A series of ruthenium(II) polypyridyl complexes were synthesized and evaluated for their in vitro anticancer activities. The results showed that ruthenium polypyridyl complexes, especially [Ru(bpy)₂(p‐tFPIP)]²⁺ ( 2 a ; bpy=bipyridine, tFPIP=2‐(2‐trifluoromethane phenyl)imidazole[4,5‐f][1,10]phenanthroline), exhibited novel anticancer activity against human cancer cell lines, but with less toxicity to a human normal cell line. The results of flow cytometry and caspase activities analysis indicated that the 2 a ‐induced growth inhibition against MG‐63 osteosarcoma cells was mainly caused by mitochondria‐mediated apoptosis. DNA fragmentation and nuclear condensation as detected by TUNEL–DAPI co‐staining further confirmed 2 a ‐induced apoptotic cell death. Further, fluorescence imaging revealed that ruthenium(II) polypyridyl complexes could target mitochondria to induce mitochondrial fragmentation, accompanied by depletion of mitochondrial membrane potential. Taken together, these findings suggest a potential application of theses ruthenium(II) complexes in the treatment of cancers.     

锌（Ⅱ）-色氨酸-邻菲咯啉配合物的合成及其与DNA的作用和生物毒性研究

合成了一种新的锌（Ⅱ）-色氨酸-邻菲咯啉配合物[Zn（Trp）（phen）2]Cl·7H2O（Ⅰ）（Trp为L-色氨酸离子,phen为邻菲咯啉）。通过元素分析、红外光谱及热重一差热分析对其进行了结构表征。采用电子吸收光谱法、荧光光谱法及琼脂糖凝胶电泳法考察了其与DNA的作用,研究了配合物对斑马鱼胚胎的生物毒性,并与2种已知结构的锌-邻菲咯啉配合物[zn（phen）2]Cl2·5H2O（Ⅱ）和[zn（phen）]Cl2（Ⅲ）进行了比较。结果表明,配合物与鲑鱼精DNA作用大小顺序为配合物Ⅰ〉配合物Ⅱ〉配合物Ⅲ．但作用方式不同;在抗坏血酸存在下,配合物Ⅰ对pBR322DNA的切割作用最强;配合物对斑马鱼胚胎毒性作用大小顺序为配合物Ⅱ〉配合物I〉配合物Ⅲ。     

N,N′-二(α-氨基吡啶)-3,6-二氧杂辛二酰胺轻稀土硝酸盐配合物的合成与表征

由轻稀土硝酸盐和开链冠醚 :N,N′-二 (α-氨基吡啶 ) - 3 ,6 -二氧杂辛二酰氨 (BDD)在非水介质中合成了组成为 Ln(NO3 ) 3 · BDD· (H2 O) n(M=La～ Eu,Pm除外 ,n=1 ,2 )的六种固体配合物。以元素分析 ,IR,1H NMR,摩尔电导及 TG- DTA等对配合物进行了表征。结果表明 ,配体在配合物中以六齿方式进行配位。     

Synthesis,characterization, and fluorescence properties of lanthanide complexes with the copolymers of 2‐butenedioic acid (z)‐mono‐ethyl ester and styrene

In this study, the luminescent macromolecular lanthanide complexes with the copolymers of styrene (St) and 2‐butenedioic acid (z)‐mono‐ethyl ester (BAME) have been synthesized, and an extensive characterization has been carried out by means of elemental analysis, FTIR, thermal analysis, and fluorescence determination. The results showed that the carboxylic groups on the chain of the polymers acted as bidentate ligands coordinated to lanthanide ions; and the coordination degree of ‐COO^?/Ln³⁺ in the macromolecular complexes was closely dependent on both the pH value of the solution and the molar ratio of St to BAME in the polymeric ligands. Thermal analysis manifested that the macromolecular complexes Ln‐PSt/BAME (Ln = Y, Sm, Dy, Eu, and Tb) were highly crosslinked and had high thermal stability and solvent resistance. The fluorescence determination indicated that Ln‐PSt/BAME complexes could emit characteristic fluorescence with comparatively high brightness and good monochromaticity, and the fluorescence intensity increased with an increasing of lanthanide content. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011     

Preparation of novel lanthanide complexes with hindered amine via solid‐state reaction and preliminary evaluation of their efficiency as light stabilizers

In this research, a series of lanthanide complexes with a low molecular weight hindered amine have been synthesized for the first time from lanthanide chloride and bis‐(2,2,6,6‐tetramethyl‐4‐piperidinyl)‐decanedioicacid (L) by simply using a solvent‐free solid‐state reaction. Elemental and thermo analysis suggest that the component of the complexes is LnLCl₃ 2H₂O (Ln = Y, La, Nd, Sm, Eu, Gd, Dy, Er). Infrared spectra indicate that the lanthanide ions are coordinated with oxygen atoms of the carbonyl group in ligand. Polypropylene films containing the ligand and complexes were prepared by melt blending and compression molding, and were exposed to UV irradiation before and after ethanol extraction. The measurements of carbonyl index, thermal decomposition temperature, and tensile elongation at break reveal that these complexes have comparable photostabilizing efficiency and improved extraction resistance compared to the ligand alone. This study suggests that hindered‐amine lanthanide complexes can provide novel approach to the cheap and efficient light stabilizers. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2010     

Synthesis,characterization of the luminescent lanthanide complexes with copolymer of (Z)‐4‐oxo‐4‐phenyloxyl‐2‐butenoic acid and styrene

The copolymers of (Z)‐4‐oxo‐4‐phenoxyl‐2‐butenoic acid with styrene (PSt/OPBA) and their macromolecular luminous lanthanide complexes (Ln‐PSt/OPBA) have been synthesized and characterized by means of GPC, elemental analysis, FTIR, X‐ray powder diffraction, spectral analysis, and thermal analysis. The IR studies showed that the carboxylic groups on the side chain of the polymer were coordinated to lanthanide ions by bidentate manner. However, the ethereal oxygen, instead of carbonyl, also bonded to the central lanthanide ions, which was an intriguing phenomenon for ester‐coordinated complexes. X‐ray diffraction experiments revealed that these PSt/OPBA copolymers were amorphous, but Ln‐PSt/OPBA were crystalline, in which the complex Eu‐L^c belonged to a high symmetric structure of orthorhombic quadratic system, with a = 10.59 ± 0.02 Å, c = 8.02 ± 0.01 Å; c/a = 0.763. In addition, the value δ (the number of free carboxylic groups) in Ln‐PSt/OPBA complexes increased with the decreasing mole ratio of styrene in the copolymers, while it decreased with increasing pH values of the solution. Eu³⁺ and Tb³⁺ complexes exhibited characteristic fluorescence with comparatively high brightness and good monochromaticity, and the fluorescence intensity was enhanced with increasing the content of lanthanide up to around 18 wt % without typical fluorescence concentration quenching behavior in the solid state. So using polymers as a matrix, Ln‐PSt/OPBA are likely to provide new materials that possess specific properties and desired features. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012     

Co2O3/Co3O4掺杂量对BaBiO3基热敏陶瓷NTC特性的影响

采用X射线衍射、扫描电子显微镜和ρ-t特性测试仪,研究了不同Co2O3/Co3O4掺杂量对BaCoⅢxBi1-xO3(x=0.02, 0.04, 0.06, 0.08) 和BaCoⅡx/3CoⅢ2x/3Bi1-xO3(x=0.02, 0.04, 0.06, 0.08)热敏陶瓷的物相、显微结构及电性能的影响.结果表明:BaCoⅢxBi1-xO3和BaCoⅡx/3CoⅢ2x/3Bi1-xO3的基本相均为钙钛矿结构的连续固溶体;Co2O3/Co3O4的含量能直接影响电学性能.试样的室温电阻率ρ25和B25~85值均随着Co2O3/Co3O4的增加呈现先下降后回升的趋势;BaCoⅢ0.06Bi0.94O3陶瓷展现出较好的NTC特性,其ρ25和B25~85值分别为12.19 Ω·cm和717 K;BaCoⅡ0.02CoⅢ0.04Bi0.94O3也获得了良好的NTC特性,其ρ25和B25~85值分别为12.32 Ω·cm和1069 K.