CPR artifact removal from human ECG using optimal multichannel filtering

The purpose of this study was to assess whether the artifacts presented by precordial compressions during cardiopulmonary resuscitation could be removed from the human electrocardiogram (ECG) using a filtering approach. This would allow analysis and defibrillator charging during ongoing precordial compressions yielding a very important clinical improvement to the treatment of cardiac arrest patients. In this investigation we started with noise-free human ECGs with ventricular fibrillation (VF) and ventricular tachycardia (VT) records. To simulate a realistic resuscitation situation, we added a weighted artifact signal to the human ECG, where the weight factor was chosen to provide the desired signal-to-noise ratio (SNR) level. As artifact signals we used ECGs recorded from animals in asystole during precordial compressions at rates 60, 90, and 120 compressions/min. The compression depth and the thorax impedance was also recorded. In a real-life situation such reference signals are available and, using an adaptive multichannel Wiener filter, we construct an estimate of the artifact signal, which subsequently can be subtracted from the noisy human ECG signal. The success of the proposed method is demonstrated through graphic examples, SNR, and rhythm classification evaluations.     

CPR Artifact Removal in Ventricular Fibrillation ECG Signals Using Gabor Multipliers

Background and objective: We present an algorithm for discarding cardiopulmonary resuscitation (CPR) components from ventricular fibrillation ECG (VF ECG) signals and establish a method for comparing CPR attenuation on a common dataset. Removing motion artifacts in ECG allows for uninterrupted rhythm analysis and reduces ldquohands-offrdquo time during resuscitation. Methods and results: The current approach assumes a multichannel setting where the information of the corrupted ECG is combined with an additional pressure signal in order to estimate the motion artifacts. The underlying algorithm relies on a localized time--frequency transformation, the Gabor transform, that reveals the perturbation components, which, in turn, can be attenuated. The performance of the method is evaluated on a small set of test signals in the form of error analysis and compared to two well-established CPR removal algorithms that use an adaptive filtering system and a state--space model, respectively. Conclusion: We primarily point out the potential of the algorithm for successful artifact removal; however, on account of the limited set of human VF and animal asystole CPR signals, we refrain from a statistical analysis of the efficiency of CPR attenuation. The results encourage further investigations in both the theoretical and the clinical setup.     

可穿戴心电信号监测中运动伪影消除技术研究

心电图(ECG)是心脏疾病诊断最有效的工具。噪声的去除和Q波、R波、S波的提取是心电信号检测中的两大主题。本文使用Savitzky-Golay滤波器对人体在弯腰、走路、坐下-站起等运动状态下采集的心电信号进行分析,去除信号中的基线漂移和运动伪影,并对滤波后信号的Q波、R波和S波进行检测。通过将本文提出的滤波方式与卡尔曼滤波、小波分解就时间复杂度和功率谱密度两个参数进行对比分析,评估Savitzky-Golay滤波器在心电信号中运动伪影去除的优势。实验结果表明,Savitzky-Golay滤波器能更加有效地适应心电信号的变化,有效地去除心电信号中的噪声,并且最大限度保持心电波形的形状和波峰。      

基于EEMD与多重分形的心电信号特征提取与分类

心电信号的快速分类在心脏病医学诊断领域具有至关重要的作用,为了降低人工识别的成本,提高心电信号分类的准确率。文章以正常搏动、房性早搏、室性早搏、左束支传导阻滞及右束支传导阻滞信号为研究对象,用集合经验模态分解分解心电信号,并结合相关系数来选取本征模态函数进行重构心电信号。从心电信号的非线性动力学角度出发,用多重分形理论进行分析,研究其质量指数曲线、广义分形维数和多重分形谱,提取合适的多重分形特征,用于支持向量机的训练。实验结果表明,用该方法训练测试30次得到的分类准确率平均值为96.09%,单次实验对正常搏动、左束支传导阻滞信号的分类精确率可达97%以上,证明该方法在心电信号分类中的有效性。     

Phase-rectified signal averaging used to estimate the dominant frequencies in ECG signals during atrial fibrillation

Phase-rectified signal averaging (PRSA) is a technique recently introduced to enhance quasi-periodic signal components. An important parameter that can be extracted from surface ECG is the dominant frequency (DF) of atrial fibrillation (AF). AF signal components are always highly contaminated by the ventricular complexes, and the cancellation of these components is never perfect. The remaining artifacts tend to induce erroneous DF estimates. In this paper, we report on the use of PRSA in the context of noninvasive AF classification procedures for improving DF estimation. The potential of PRSA is demonstrated by experiments both on synthetic and clinical ECG signals.     

基于卷积长短时记忆网络的心律失常分类方法

心律失常等慢性心血管疾病严重影响人类健康,采用心电信号(ECG)实现心律失常自动分类可有效提高该类疾病的诊断效率,降低人工成本。为此,该文基于1维心电信号,提出一种改进的长短时记忆网络(LSTM)方法实现心律失常自动分类。该方法首先设计深层卷积神经网络(CNN)对心电信号进行深度编码,提取心电信号形态特征。其次,搭建长短时记忆分类网络实现基于心电信号特征的心律失常自动分类。基于MIT-BIH心律失常数据库进行的实验结果表明,该方法显著缩短分类时间,并获得超过99.2%的分类准确率,灵敏度等评价参数均得到不同程度的提高,满足心电信号自动分类实时高效的要求。     

Motion artifact reduction in photoplethysmography using independent component analysis

Removing the motion artifacts from measured photoplethysmography (PPG) signals is one of the important issues to be tackled for the accurate measurement of arterial oxygen saturation during movement. In this paper, the motion artifacts were reduced by exploiting the quasi-periodicity of the PPG signal and the independence between the PPG and the motion artifact signals. The combination of independent component analysis and block interleaving with low-pass filtering can reduce the motion artifacts under the condition of general dual-wavelength measurement. Experiments with synthetic and real data were performed to demonstrate the efficacy of the proposed algorithm.     

Removal of CPR artifacts from the ventricular fibrillation ECG by adaptive regression on lagged reference signals

BACKGROUND AND OBJECTIVE: Removing cardiopulmonary resuscitation (CPR)-related artifacts from human ventricular fibrillation (VF) electrocardiogram (ECG) signals provides the possibility to continuously detect rhythm changes and estimate the probability of defibrillation success. This could reduce "hands-off" analysis times which diminish the cardiac perfusion and deteriorate the chance for successful defibrillations. METHODS AND RESULTS: Our approach consists in estimating the CPR part of a corrupted signal by adaptive regression on lagged copies of a reference signal which correlate with the CPR artifact signal. The algorithm is based on a state-space model and the corresponding Kalman recursions. It allows for stochastically changing regression coefficients. The residuals of the Kalman estimation can be identified with the CPR-filtered ECG signal. In comparison with ordinary least-squares regression, the proposed algorithm shows, for low signal-to-noise ratio (SNR) corrupted signals, better SNR improvements and yields better estimates of the mean frequency and mean amplitude of the true VF ECG signal. CONCLUSIONS: The preliminary results from a small pool of human VF and animal asystole CPR data are slightly better than the results of comparable previous studies which, however, not only used different algorithms but also different data pools. The algorithm carries the possibility of further optimization.     

Directional diamond search pattern for fast block motion estimation

A new fast block matching algorithm (BMA) with a directional diamond search (DDS) pattern is proposed, which is designed to fit the directional centre-biased motion vector distribution. Simulation results show that the DDS algorithm has a significant computational speedup compared to other popular fast BMAs, with similar or even better performance.     

Image-based gating of intravascular ultrasound pullback sequences

Intravascularultrasound (IVUS) sequences recorded in vivo are subject to a wide array of motion artifacts as the majority of these studies are performed within the coronary arteries of a beating heart. To eliminate these artifacts, an electrocardiogram (ECG) signal is typically used to gate (collect) those frames recorded at the points in time associated with a particular fraction of the cardiac cycle. However, this technique may be suboptimal for a number of reasons, among which is the difficulty of determining the optimal fraction at which to gate. This value is generally nonobvious. To circumvent this problem, we introduce a frame-gating method for IVUS pullbacks that mimics ECG (i.e., in the sense that it selects only one frame per cardiac cycle), but will automatically choose the fraction of the cycle that renders the most stable gated frame set. Stability here is gauged by measuring interframe similarity. Our method operates exclusively on the imagery data and does not require ECG or any form of image segmentation or other high-level image analysis. To validate our algorithm, we compare its behavior versus true ECG gating.     

Noise cancellation signal processing method and computer system for improved real-time electrocardiogram artifact correction during MRI data acquisition

A system was developed for real-time electrocardiogram (ECG) analysis and artifact correction during magnetic resonance (MR) scanning, to improve patient monitoring and triggering of MR data acquisitions. Based on the assumption that artifact production by magnetic field gradient switching represents a linear time invariant process, a noise cancellation (NC) method is applied to ECG artifact linear prediction. This linear prediction is performed using a digital finite impulse response (FIR) matrix, that is computed employing ECG and gradient waveforms recorded during a training scan. The FIR filters are used during further scanning to predict artifacts by convolution of the gradient waveforms. Subtracting the artifacts from the raw ECG signal produces the correction with minimal delay. Validation of the system was performed both off-line, using prerecorded signals, and under actual examination conditions. The method is implemented using a specially designed Signal Analyzer and Event Controller (SAEC) computer and electronics. Real-time operation was demonstrated at 1 kHz with a delay of only 1 ms introduced by the processing. The system opens the possibility of automatic monitoring algorithms for electrophysiological signals in the MR environment.     

Strain-Isolating Materials and Interfacial Physics for Soft Wearable Bioelectronics and Wireless,Motion Artifact-Controlled Health Monitoring

Recent developments of micro-sensors and flexible electronics allow for the manufacturing of health monitoring devices, including electrocardiogram (ECG) detection systems for inpatient monitoring and ambulatory health diagnosis, by mounting the device on the chest. Although some commercial devices in reported articles show examples of a portable recording of ECG, they lose valuable data due to significant motion artifacts. Here, a new class of strain-isolating materials, hybrid interfacial physics, and soft material packaging for a strain-isolated, wearable soft bioelectronic system (SIS) is reported. The fundamental mechanism of sensor-embedded strain isolation is defined through a combination of analytical and computational studies and validated by dynamic experiments. Comprehensive research of hard-soft material integration and isolation mechanics provides critical design features to minimize motion artifacts that can occur during both mild and excessive daily activities. A wireless, fully integrated SIS that incorporates a breathable, perforated membrane can measure real-time, continuous physiological data, including high-quality ECG, heart rate, respiratory rate, and activities. In vivo demonstration with multiple subjects and simultaneous comparison with commercial devices captures the SIS's outstanding performance, offering real-world, continuous monitoring of the critical physiological signals with no data loss over eight consecutive hours in daily life, even with exaggerated body movements.     

Hardware Efficient Double Diamond Search Block Matching Algorithm for Fast Video Motion Estimation

Application of video in multimedia communication has become feasible due to efficient block matching algorithm (BMA) based motion estimation (ME) and motion compensation (MC) methods, that facilitate high data compression. To sustain visual quality of video, large amount of computation is involved in ME which can be reduced by fast search BMA and making fast search faster by various means like predicting initial search center (ISC) and early search termination. But more challenging work is to design an architecture which performs computation hungry search process in fewer clock cycles which will actually make fast search rapid for real time encoding. Implementations are available for matching multiple macroblocks in single clock cycle, but bottleneck is accessing macroblocks from memory while following sequential irregular search patterns of most of fast search algorithms. This paper proposes a novel, Hardware Efficient Double Diamond Search (HEDDS) algorithm which reaches far in search window more rapidly to identify best match and minimizes number of iterations of search pattern and hence diminish required clock cycles to read macroblocks from memory. From implementation perspective, HEDDS is up to 7.5 % to 33 % faster than existing BMAs and also offers reasonably good quality of encoding. With variable block size, HEDDS demonstrate average BD-PSNR improvement of 0.381, 0.088, 0.87 and 0.233 dB at BD-bitrate drop of 12.994 %, 2.499 %, 25.599 %, 6.887 % in comparison of HS, HMDS, LDPS and UMHS correspondingly. Proposed HEDDS architecture can process 259 HD frames per second in average case for fixed block size which is promising figure for real time encoding on devices having inadequate computational resources.     

Weighted conditional random fields for supervised interpatient heartbeat classification

This paper proposes a method for the automatic classification of heartbeats in an ECG signal. Since this task has specific characteristics such as time dependences between observations and a strong class unbalance, a specific classifier is proposed and evaluated on real ECG signals from the MIT arrhythmia database. This classifier is a weighted variant of the conditional random fields classifier. Experiments show that the proposed method outperforms previously reported heartbeat classification methods, especially for the pathological heartbeats.     

ECG biometric analysis in cardiac irregularity conditions

Biometric traits offer direct solutions to the critical security concerns involved in identity authentication systems. In this paper, a systematic analysis of the electrocardiogram (ECG) signal for application in human recognition is reported, suggesting that cardiac electrical activity is highly personalized in a population. Features extracted from the autocorrelation of healthy ECG signals embed considerable diacritical power, and render fiducial detection unnecessary. The central consideration of this paper is the evaluation of an identification system that is robust to common cardiac irregularities such as premature ventricular contraction (PVC) and atrial premature contraction (APC). Criteria concerning the power distribution and complexity of ECG signals are defined to bring to light abnormal ECG recordings, which are not employable for identification. Experimental results indicate a recognition rate of 96.2% and render identification based on ECG signals rather promising.     

脑电信号预处理方法研究综述

脑电信号是一种复杂且重要的生物信号,被广泛应用于类脑智能技术和脑机接口领域的研究。文中介绍了干扰正常脑电信号的常见非生理性伪迹和生理性伪迹的类型及特点,并对生理性伪迹的产生原因进行了详细分析。通过对各种脑电信号去除伪迹方法的回顾以及应用现状的分析,比较并总结了传统去除伪迹方法和新型去除伪迹方法的研究进展,并进一步分析去除伪迹方法的优缺点。部分方法已经成功应用于处理脑电信号中的眼电、心电和肌电等伪迹中。文中还针对目前脑电信号去除伪迹的需求及所面临的问题给出了应对策略,并对未来的研究方向进行了分析和展望。     

Epilepsy analysis using open source EDF tools for information science and data analytics

Electroencephalogram (EEG) is the signals that measure the electrical variances of brain using metal electrodes. We observe the EEG signals by using European Data Format (EDF) BROWSER and EEG STUDIO. By using EDF BROWSER, we can get the mean and frequency from the filtered output signal using band‐pass filter. Using EDF BROWSER, we can also perform Root Mean Square (RMS) and signal samples. Using EEG STUDIO, we can analyze the average frequency and standard deviation. Epileptic seizure prediction and detection are done by spike detection, frequency domain analysis, and nonlinear methods. EEG signal contains different artifacts like electrooculography (EOG), EKG, and electrocardiogram (ECG). ECG signals are produced by heart. EOG signals are produced by eyes. EMG signals are produced by muscle coordination.     

Novel ECG Signal Classification Based on KICA Nonlinear Feature Extraction

Electrocardiogram (ECG) signal feature extraction is important in diagnosing cardiovascular diseases. This paper presents a new method for nonlinear feature extraction of ECG signals by combining principal component analysis (PCA) and kernel independent component analysis (KICA). The proposed method first uses PCA to decrease the dimensions of the ECG signal training set and then employs KICA to calculate the feature space for extracting the nonlinear features. Support vector machine (SVM) is utilized to determine the nonlinear features of the ECG signal classification. Genetic algorithm is also used to optimize the SVM parameters. The proposed method is advantageous because it does not require a huge amount of sampling data, and this technique is better than traditional strategies to select optimal features in the multi-domain feature space. Computer simulations reveal that the proposed method yields more satisfactory classification results on the MIT–BIH arrhythmia database, reaching an overall accuracy of 97.78 %.     

QRS feature extraction using linear prediction

This communication proposes a method called linear prediction (a high performant technique in digital speech processing) for analyzing digital ECG signals. There are several significant properties indicating that ECG signals have an important feature in the residual error signal obtained after processing by Durbin's linear prediction algorithm. This communication also indicates that the prediction order need not be more than two for fast arrhythmia detection. The ECG signal classification puts an emphasis on the residual error signal. For each ECG's QRS complex, the feature for recognition is obtained from a nonlinear transformation which transforms every residual error signal to a set of three states pulse-code train relative to the original ECG signal. The pulse-code train has the advantage of easy implementation in digital hardware circuits to achieve automated ECG diagnosis. The algorithm performs very well in feature extraction in arrhythmia detection. Using this method, our studies indicate that the PVC (premature ventricular contraction) detection has at least a 92 percent sensitivity for MIT/BIH arrhythmia database.     

在运动状态下脉搏信号的级联滤波算法

为了减小在剧烈环境中脉搏波信号产生的运动伪迹,采用mimic数据库中由光子器件构成的光电传感器采集的脉搏信号,通过陀螺仪信号和三轴加速度互补滤波来矫正三轴加速度的角度,运用奇异谱分析将矫正后的三轴加速度信号分组为不同频率成分的信号,作为三级快速横向递归最小二乘(FTRLS)算法的参考信号自适应消除运动伪迹.结果表明,与...