共查询到20条相似文献,搜索用时 15 毫秒
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Physico‐chemical,antioxidant, and anti‐inflammatory properties and stability of hawthorn (Crataegus monogyna Jacq.) procyanidins microcapsules with inulin and maltodextrin 下载免费PDF全文
Dorota Wyspiańska Alicja Z Kucharska Anna Sokół‐Łętowska Joanna Kolniak‐Ostek 《Journal of the science of food and agriculture》2017,97(2):669-678
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B. Vogelgesang I. Bonnet N. Godard B. Sohm E. Perrier 《International journal of cosmetic science》2011,33(2):120-125
Most of adult women exhibit cellulite on the hips, buttock and thighs. Although extracellular matrix and lymphatic system disorders can increase its appearance, cellulite basically results from an excessive fat storage in the adipose tissue which exerts considerable pressure on the surrounding skin tissue and creates a dimpled irregular appearance. Caffeine, the most widely used anti‐cellulite ingredient, favours fat break‐down by inhibiting the phosphodiesterase enzyme and encouraging a high intracellular level of cAMP. A series of studies has shown that spermine and spermidine, two ubiquitous polyamines, encouraged fat storage and slowed fat break‐down in the adipose tissue. Besides, it was shown that heparan sulfate glycosaminoglycans had a strong affinity for polyamines. To design a new cosmetic ingredient with anti‐cellulite properties, we used molecular modelling to screen several ingredients with a structure similar to that of heparan sulfate glycosaminoglycans. This way, we identified sulfo‐carrabiose as a potent molecule for trapping spermine and spermidine. These virtual results were first confirmed in tubo where sulfo‐carrabiose was shown to dose‐dependently inactivate spermine and spermidine. In vitro, adipocytes cultured with sulfo‐carrabiose exhibited a significant reduction of lipogenesis and a significant increase of lipolysis. When sulfo‐carrabiose was incorporated in a cosmetic formula, significant improvements were observed in thigh circumference, with better results than those obtained with caffeine after 28 days of use. Furthermore, a combination of caffeine and sulfo‐carrabiose led to results significantly better than those obtained with caffeine alone. As measured by fringe projection, thigh volume was also significantly reduced after sulfo‐carrabiose treatment. Finally, the appearance of cellulite assessed by clinical evaluation was also significantly reduced within 28 days. 相似文献
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Therapeutic effects of silymarin and naringin on methotrexate‐induced nephrotoxicity in rats: Biochemical evaluation of anti‐inflammatory,antiapoptotic, and antiautophagic properties 下载免费PDF全文
Fatih Mehmet Kandemir Sefa Kucukler Cuneyt Caglayan Cihan Gur Annour Adoum Batil İlhami Gülçin 《Journal of Food Biochemistry》2017,41(5)
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Hepatoprotective effects of different combinations of sweet orange,Unshiu mikan,and mini tomato juice powders against tert‐butyl hydroperoxide‐induced oxidative stress in HepG2 cells 下载免费PDF全文
Susoma Jannat Md Yousof Ali Hyeung‐Rak Kim Prashamsa Koirala Hyun Ah Jung Jae Sue Choi 《Journal of Food Biochemistry》2017,41(3)
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In vitro anti‐inflammatory properties of fermented pepino (Solanum muricatum) milk by γ‐aminobutyric acid‐producing Lactobacillus brevis and an in vivo animal model for evaluating its effects on hypertension 下载免费PDF全文
Vincent Hung‐Shu Chang Tsai‐Hsin Chiu Szu‐Chieh Fu 《Journal of the science of food and agriculture》2016,96(1):192-198
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Young‐Ran Song Nam‐Sik Shin Sang‐Ho Baik 《International Journal of Food Science & Technology》2014,49(11):2491-2498
The aim of this study was to utilise by‐product pepper leaves for vinegar production due to its nutritional value. Changes in physicochemical and functional properties in four main process from raw material (leaves) to lactic acid (juice), alcohol (wine) and acetic acid (vinegar) fermentations were evaluated and compared. Their nutritional compositions were significantly different and particularly the wine and vinegar had higher total phenol content and their expanded diversity than the juice and then leaves (P < 0.05). Difference in values for phenolic compound was highly correlated with their α‐glucosidase inhibitory (AGI) and antioxidant capacities in DPPH and superoxide radical scavenging and reducing power assays (r = 0.919–0.981); vinegar ≥ wine > juice > leaves. Especially, AGI activity was greatly enhanced depending on fermentation steps beyond expectation. Thus, these data confirm that pepper leaves is a good functional source and the vinegar fermentation improved the functionality in stages. 相似文献
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Panchita Phuwamongkolwiwat Tohru Hira Hiroshi Hara 《Molecular nutrition & food research》2014,58(7):1581-1584
This study conducted in vivo and in situ experiments with rats to investigate the glucagon‐like peptide‐1 (GLP‐1) secretion in response to oral or ileal administration of α‐glucosyl‐isoquercitrin (20–40 mmol in 2 mL; Q3G), fructooligosaccharides (200 mmol in 2 mL; FOS) and Q3G + FOS. Direct effects on GLP‐1‐producing l ‐cells were also examined by an in vitro study using a murine enteroendocrine cell line, GLUTag. To evaluate the plasma GLP‐1 level, blood samples from jugular cannula for in vivo and portal cannula for in situ experiments were obtained before and after administration of Q3G, FOS, or Q3G + FOS. We found tendencies for increases but transient stimulation of GLP‐1 secretion by Q3G in in vivo and in situ experiments. Although FOS alone did not have any effects, Q3G + FOS enhanced and prolonged high plasma GLP‐1 level in both experiments. In addition, application of Q3G on GLUTag cells stimulated GLP‐1 secretion while FOS enhanced the effect of Q3G. Our results suggest that Q3G + FOS possess the potential for the management or prevention of Type 2 diabetes mellitus (T2DM) by enhancing and prolonging the GLP‐1 secretion via direct stimulation of GLP‐1 producing l ‐cell. 相似文献
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Cardamom supplementation improves inflammatory and oxidative stress biomarkers in hyperlipidemic,overweight, and obese pre‐diabetic women: a randomized double‐blind clinical trial 下载免费PDF全文
Shiva Kazemi Fatemeh Yaghooblou Fereydoun Siassi Abbas Rahimi Foroushani Mahsa Ghavipour Fariba Koohdani Gity Sotoudeh 《Journal of the science of food and agriculture》2017,97(15):5296-5301
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Anti‐inflammatory potential of black carrot (Daucus carota L.) polyphenols in a co‐culture model of intestinal Caco‐2 and endothelial EA.hy926 cells 下载免费PDF全文
Senem Kamiloglu Charlotte Grootaert Esra Capanoglu Ceren Ozkan Guy Smagghe Katleen Raes John Van Camp 《Molecular nutrition & food research》2017,61(2)
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Solid‐phase extraction and spectrophotometric determination of Allura Red (E129) in foodstuff,soft drink,syrup and energy drink samples: a comparison study 下载免费PDF全文
Abdullah Taner Bişgin Yavuz Sürme Mustafa Uçan İbrahim Narin 《International Journal of Food Science & Technology》2016,51(11):2367-2375
Amberlite XAD‐7 and XAD‐8 resins were used as adsorbents for preconcentration and determination of Allura Red (AR) food dye in aqueous medium. The effects of pH, sample volume, sample and eluent flow rates on the extraction of AR were optimised. The determination of dye was performed at 506.0 nm using spectrophotometry. Interference effects of matrix ions and some dyes were also investigated under optimised conditions. The methods permitted low detection limits which were 1.2 and 0.6 μg L?1 for XAD‐7 and XAD‐8, respectively. Adsorption behaviours were investigated by adsorption isotherms and zero charge pH experiments. Validations of the method were performed by determination of AR contents in some foodstuffs. AR contents of liquid samples were found between 58 and 440 μg mL?1. AR concentrations of solid samples were between 416 and 432 μg g?1. The XAD‐7 and XAD‐8 resins presented a fast and reliable potential to determine AR dye in real samples. 相似文献