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Background

Systems medicine is characterized by the integration of large amounts of data from manifold data sources and links approaches of systems biology and medical science with informatics and predictive methods of mathematical modeling. This results in a close cooperation of physicians and scientists. Therefore, the expertise of researchers becomes increasingly important regarding the processing and interpretation of patient data. This raises questions of how cooperation between the different actors is managed and to what extent and how the roles and ascribed responsibilities of physicians and scientists change in the context of systems medicine.

Methods

To answer these questions, we conducted a qualitative interview study with physicians and researchers from different fields of systems medicine in order to reconstruct their experiences and perceptions.

Results and conclusions

Based on the empirical analysis two conceptions of systems medicine can be identified. The first conception is characterized by a clear division of competences and tasks between physicians and researchers: researchers serve as service providers, physicians as translational, interdisciplinary trained experts. In the second conception, the division of competences and tasks between physicians and researchers can no longer strictly be drawn: professionals act as a multidisciplinary team, implying close mutual cooperation. Both conceptions indicate (potential) role conflicts of physicians and researchers particularly resulting from the discrepancy between medical and science ethos as well as their specific norms of conduct and objectives. As a consequence, from a normative perspective, it should be clarified which responsibilities legitimately can be attributed to physicians and researchers working in systems medicine. In this regard, it seems to be appropriate to differentiate between more patient-orientated contexts of medical care and fields of basic research.
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