Clinical diagnostic valuation cine magnetic resonance coronary angiography

OBJECTIVES: This biomechanical cadaver study was performed to compare the fixation stability of a standard lateral condylar buttress plate with a similar condylar buttress plate with the distal screws locked to the plate. Then the study was repeated with six additional matched femoral pairs to compare the locked plate with a standard 95-degree blade plate. DESIGN: Six matched pairs of mildly osteopenic femurs were selected, and each side was assigned randomly to fixation with either a standard lateral condylar buttress plate or a modified lateral condylar buttress plate with locked distal screws. The experiment was repeated with six additional matched pairs of femurs instrumented with either a modified lateral condylar buttress plate with locked distal screws or a standard 95-degree blade plate. INTERVENTION: The femurs were instrumented, and a gap osteotomy was created at the distal femoral metaphysis. The instrumented femurs were then mechanically tested in axial compression and bending/torsional loading to determine fixation stability; then they were loaded at 1,000 newtons for 10(5) cycles and retested for stability. MAIN OUTCOME MEASUREMENT: The displacement across the osteotomy gap at 100-newton and 1,000-newton axial loads was measured directly for each specimen before and after cycling. In addition, resistance to displacement in bending/torsional loading (newtons/centimeter) was determined from load/displacement curves, before and after cycling. RESULTS: The locked buttress plate provided significantly greater fixation stability than the standard plate both before and after cycling in axial loading. The locked buttress plate also proved significantly more stable in axial loading than the blade plate both before and after cycling. CONCLUSION: A condylar buttress plate with locked screws is a valid concept for improving fixation stability.     

Delayed surgical fixation of femur fractures is a risk factor for pulmonary failure independent of thoracic trauma

A recent retrospective analysis of femur fractures concluded that early surgical fixation in patients who have sustained blunt thoracic trauma (AIS score for Thorax > or = 2) was a risk factor for postoperative pulmonary failure. We conducted a review of all femur fractures admitted to a level I trauma center from November, 1988 to May, 1993. Inclusion criteria were ISS > or = 18, mid-shaft femur fractures treated with reamed intramedullary fixation, and no mortalities secondary to head trauma or hemorrhagic shock. One hundred thirty-eight patients met these criteria. Four patient groups were created: N1--no thoracic trauma (AIS score for thorax < 2), and early surgical fixation (< 24 hours after injury, n = 49); N2--no thoracic trauma and delayed fixation (> or = 24 hours, n = 8); T1--thoracic trauma (AIS score for Thorax > or = 2) and early fixation (n = 56); T2--thoracic trauma and delayed fixation (n = 25). There were no significant differences in age, Injury Severity Score, or Glasgow Coma Scale score between the four groups. Mortality rate, length of stay (LOS), LOS in the TICU, and duration of mechanical ventilation tended to be greater in patients with delayed fracture fixation, however, this was not statistically significant. The N2 patients had a pneumonia rate of 38% compared with 10% in group N1 (p = 0.07). The T2 patients had a pneumonia rate of 48% compared with 14% in group T1 (p = 0.002).(ABSTRACT TRUNCATED AT 250 WORDS)     

Effects of passive tilt and submaximal exercise on spectral heart rate variability in ventricular fibrillation patients without significant structural heart disease

It has been shown that tilt and exercise elicit significant changes in autonomic activity in normal subjects and that submaximal exercise causes a greater reduction in heart rate variability (HRV) in animals susceptible to ventricular fibrillation (VF). Whether there is an abnormal HRV response to tilt and exercise in patients at risk of sudden cardiac death (SCD) remains unknown. Short-term HRV before and during passive tilt and exercise was studied in 12 survivors of out-of-hospital cardiac arrest with documented VF and compared with 12 age- and sex-matched normal controls. No patient had significant structural heart disease or left ventricular dysfunction. HRV was computed as total-frequency (TF, 0.01 to 1.00 Hz), low-frequency (LF, 0.04 to 0.15 Hz) and high-frequency (HF, 0.15 to 0.40 Hz) components. There was no significant difference between normal controls and SCD survivors in HRV before or during tilt or submaximal exercise testing. The HF component was significantly decreased during tilt compared with that in the supine position in both normal controls (5.85 +/- 0.61 vs 5.08 +/- 0.95 In(msec2), p = 0.005) and patients (5.58 +/- 1.49 versus 4.74 +/- 1.18 In(msec2), p = 0.003). There was again no significant change in the TF or LF components during tilt in either patients or controls. All frequency components were significantly decreased during submaximal exercise testing in both patients and controls. However, there was no significant difference in any of these tilt- and exercise-induced changes in HRV between normal controls and SCD survivors.(ABSTRACT TRUNCATED AT 250 WORDS)     

Design and biomechanics of a plate for the distal radius

A dorsal plate for the distal radius was designed to provide rigid fixation and thus allow early motion. It functions as a blade plate, lessening the role of metaphyseal screws, and providing internal neutralization rather than compression. The rigidity and strength of the plate were compared to the existing T-plate in an unstable, extra-articular fracture model in paired, fresh-cadaver, axially loaded radii. The dorsal plate construct was significantly stronger and more rigid than the T-plate construct. The failure mode was similar for both plate types; 8 of 10 constructs failed with plate bending and screw loosening, while the oldest specimen pair showed primary bone failure. Compared to the T-plate, the dorsal plate transmitted a greater single axial load from the articular surface to the shaft.     

舞钢4100mm宽厚板生产线双边剪退刀拉杆断裂原因分析

针对舞钢公司4 100 mm宽厚板生产线双边剪退刀拉杆断裂事故,根据退刀机构的工作原理,对退刀拉杆进行了受力分析,最终找出断裂的主要原因并采取改进措施,避免了同类事故再次发生。     

Experimental Analysis of Crack Growth in GFRP Reinforced Concrete

For decades, bridge slabs have been troubled by the corrosion of steel reinforcement. The unique corrosion resistance of glass fiber-reinforced polymer (GFRP) bars makes them a promising alternative to steel bars. Experiments have been conducted to investigate the bond performance of GFRP reinforced concrete under constant amplitude cyclic fatigue loading. Each specimen was an identical length beam with a single GFRP bar at the bottom, intended to simulate a transverse strip of a typical bridge deck slab. The crack growth was monitored for specimens of different widths, simulating different transverse reinforcement spacings. Up to 2?million?cycles of cyclic loads were applied at 100% typical service load levels. No fatigue failure was encountered in the testing. The effects of moderate overloads were also investigated.     

Phase transformation of stainless steel during fatigue

Transformation of austenite during cyclic loading was studied in AISI 301 and 304 alloys whose stability was adjusted by heat treatment and temperature changes. Fatigue life was determined under controlled strain amplitude tension-compression conditions. The amount of transformation to α’ (bcc) martensite was continuously indicated magnetically during testing, and the α’ and ∈ (hcp) phases were observed metallographically at failure. It was found in room temperature testing that at strain amplitudes in excess of 0.4 pct the formation of α’ (bcc) martensite was detrimental to the fatigue life. At 200°F (366 K) the fatigue life of an unstable alloy was increased, while in a completely stable austenitic alloy (20Cr, 6Ni, 9Mn), the life at 200°F (366 K) was less than that at room temperature for the same cyclic strain amplitude. The differing effect of temperature on life of these two types of alloy is attributed to the alteration of the austenite stacking fault energy and the relative free energies of the α’ (bcc), ∈ (hcp) and γ (fcc) phases in the unstable alloys. It has been observed that within the standard composition ranges of the two 300 series stainless steel grades there can be marked differences in the degree of transformation resulting from cyclic loading. This has the implication that for fatigue applications modifications in the specifications for the different grades of stainless would be advantageous.     

Implant-supported overdenture therapy: a retrospective study

All patients (n = 46) treated with implant-supported overdentures at the Department of Prosthetic Dentistry, Dental and Medical Health Centre, Halmstad, Sweden, from 1986 to 1993 were studied. The clinical examination was completed in 1994. The material was divided into two subgroups: Group A had been initially treatment planned for an implant-supported overdenture, and Group B had been planned for fixed prostheses but because of loss of implants before loading, treatment with a fixed prosthesis was not possible. The authors present their experience and patient reactions to overdenture therapy in two defined groups of patients. The implant failure rate before loading for Group A (n = 12) was 15% (six implants out of 39), and the rate before loading for Group B (n = 29) was 43.6% (68 implants out of 156). After prosthodontic treatment in Group A, the implant success rate after loading was 87.9%, and the overdenture stability was 84.6%. In group B, 17 implants placed in the maxillae were lost after overdenture therapy, which resulted in an implant success rate of 79.3%. A total of eight overdentures, all of which had been placed in the maxillae, were lost, resulting in an overdenture stability of 73.3%. In this study "change of retentive clips" was the predominant prosthodontic complication related to the overdentures, especially in Group B. Most of these complications (62%) occurred in patients with clinical signs of bruxism. Patient reactions to treatment with an overdenture were positive regarding esthetics for both groups. More negative views were recorded in Group B than in Group A in response to function and retention of the overdenture.     

Prediction of fatigue screw loosening in anterior spinal fixation using dual energy x-ray absorptiometry

STUDY DESIGN: A biomechanical study was performed to investigate a relation between the bone mineral density of the vertebral body and the number of loading cycles to induce fatigue loosening of an anterior vertebral screw. OBJECTIVES: The objective of this study was to investigate the potential usefulness of dual energy x-ray absorptiometry of measuring bone mineral density of the vertebral body in predicting the fatigue loosening of th anterior vertebral screw. SUMMARY OF BACKGROUND DATA: Loosening of the vertebral body screw is a well know failure in spinal instrumentation, and more commonly observed than pullout failure. The relation between bone mineral density and pullout strength of the screw has been investigated previously, but no studies are available on the fatigue loosening in anterior spinal fixation. METHODS: Bone mineral density was measured using dual energy x-ray absorptiometry and the screw loosening was produce by a cyclic loading in the cephalad-caudal direction. Screw loosening was defined as 1 mm displacement of the screw relative to bone, and the number of loading cycles to induce the screw loosening was obtained and statistically correlated with bone mineral density. RESULTS: There was a positive correlation between the number of loading cycles to induce screw loosening and bone mineral density (R = 0.8, P < 0.01). The average number of loading cycles to induce screw loosening was significantly less for specimens with bone mineral density < 0.45 g/cm2 compared to those with bone mineral density > or = g/cm2. CONCLUSIONS: These findings suggest that bone mineral density may be a good predictor of anterior vertebral screw loosening. Bone mineral density < 0.45 g/cm2 may be critical value of loosening of the anterior vertebral body screw. However, further biomechanical and clinical studies are required before using threshold value clinically.     

The evolution of femoral shaft plating technique

There has been an evolution in the AO/Association for the Study of Internal Fixation plating technique during the past 3 decades that includes the use of longer plates and fewer plate screws, fewer lag screws outside the plate, fewer unicortical screws at the plate periphery, and greater use of the 95 degrees blade plate to achieve balanced fixation of proximal and distal shaft fractures. These changes reflect an evolving technique of plate osteosynthesis that emphasizes indirect reduction techniques, biologic internal fixation, and improved biomechanics. Outcome data suggest that there has been an improvement with time that is reflected by shorter time to union, a decrease in the frequency of implant failures, delayed unions, nonunions, malunions, number of reoperations, and in overall rate of failure. The best predictor of success was the length of plate by logistic regression analysis. With the evolution of plating techniques and a greater emphasis on biology of fracture healing, the incidence of complications and failures has decreased after femoral shaft plating. Plate osteosynthesis of the femoral shaft is particularly advantageous in many situations and can be quite successful (87% success rate in Group III).     

阻尼器用低屈服点钢BLY160的低周疲劳性能

对BLY160低屈服点钢低周疲劳性能进行了研究。采用轴向应变控制方法,在MTS809电液伺服疲劳试验机上开展低周疲劳试验,分别研究了在循环载荷作用下试验材料的循环应力响应特征、循环应力与应变的关系以及应变幅和应变速率对材料低周疲劳性能的影响。试验结果表明,BLY160钢具有良好的低周疲劳性能,完全满足耗能阻尼器用钢的需要。     

Phase transformation of stainless steel during fatigue

Transformation of austenite during cyclic loading was studied in AISI 301 and 304 alloys whose stability was adjusted by heat treatment and temperature changes. Fatigue life was determined under controlled strain amplitude tension-compression conditions. The amount of transformation to α’ (bcc) martensite was continuously indicated magnetically during testing, and the α’ and ∈ (hcp) phases were observed metallographically at failure. It was found in room temperature testing that at strain amplitudes in excess of 0.4 pct the formation of α’ (bcc) martensite was detrimental to the fatigue life. At 200°F (366 K) the fatigue life of an unstable alloy was increased, while in a completely stable austenitic alloy (20Cr, 6Ni, 9Mn), the life at 200°F (366 K) was less than that at room temperature for the same cyclic strain amplitude. The differing effect of temperature on life of these two types of alloy is attributed to the alteration of the austenite stacking fault energy and the relative free energies of the α’ (bcc), ∈ (hcp) and γ (fcc) phases in the unstable alloys. It has been observed that within the standard composition ranges of the two 300 series stainless steel grades there can be marked differences in the degree of transformation resulting from cyclic loading. This has the implication that for fatigue applications modifications in the specifications for the different grades of stainless would be advantageous. Formerly a Research Assistant     

Perception of expiratory flow by asthmatics and non-asthmatics during rest and exercise.

The perception of normal and asthmatic individuals was assessed using a magnitude production procedure in a series of 3 studies, testing 10 male and 10 female 20–30 yr old Ss during rest, then 9 female 20–35 yr old Ss during submaximal exercise (both groups with no history of respiratory disease), and 10 12–18 yr old male asthmatics using no steroid medication and 10 nonasthmatic age- and sex-matched controls during rest and submaximal exercise. Findings do not support an abnormality in perception occurring during exercise in asthma patients. (18 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Effect of Microfabric on Undrained Static and Cyclic Behavior of Kaolin Clay

Microfabric plays an important role in the engineering behavior of soils. Although many studies are available in the literature on the effect of microfabric on the static behavior of soils, the effect on the cyclic behavior is less understood. In the present study, samples with different microfabric were prepared in the laboratory by reconstituting commercially available kaolin clay with different pore fluids under a consolidation pressure of 100?kPa. Consolidated undrained triaxial tests were carried out on these samples under static and cyclic loading conditions. Dispersed samples were found to have monotonic stress-strain behavior with a peak deviatoric stress and higher peak undrained shear strength than the flocculated samples. However, the dispersed samples were found to offer less resistance to cyclic loading. When subjected to cyclic loading, dispersed samples failed within a few cycles under a cyclic stress ratio (defined as the ratio of cyclic deviatoric stress to the undrained shear strength) close to 0.6, whereas in flocculated samples, sudden failure was not observed even at a higher cyclic stress ratio of 0.9, although strains and pore pressures accumulated to higher values. Postcyclic monotonic tests conducted on samples that did not fail under cyclic loading showed an apparent overconsolidation effect caused by cyclic loading in a similar manner, as reported in the literature.     

Cyclic fatigue of a model feldspathic porcelain

OBJECTIVES: This study was conducted to evaluate the fatigue parameters of a model porcelain based on the Weinstein patent using cyclic fatigue and to compare the parametric values obtained from cyclic fatigue tests with those from dynamic fatigue tests previously reported by Fairhurst et al. (1993). METHODS: Cyclical biaxial flexure of 1 mm thick and 12 mm diameter disks was performed at 37 degrees C in distilled water at a frequency of 4 Hz with constant stressing rates between a minimum and maximum stress. Three groups of samples (50, 40, 40) were tested with a maximum stress of 51, 47, and 43 MPa, respectively. The crack growth exponent, n, and the scaling constant, sigma fo, were derived from the regression constants obtained from a linear regression of the logarithm of the median time to failure with the logarithm of the maximum stress. RESULTS: No significant differences were found between the cyclic fatigue parameters, n and sigma fo, derived from the median time to failure and those obtained from dynamic fatigue data. SIGNIFICANCE: Within the limits of error in this determination, the median cyclic fatigue life can be estimated by the use of fatigue parameters obtained from dynamic fatigue testing.     

Crack propagation in ceramic materials under cyclic loading conditions

An analysis is presented which enables crack propagation rates under cyclic loading condiditions to be predicted from static slow crack growth parameters. A comparison of the predicted times to failure under cyclic conditions with available measured failure times, for several ceramic materials at ambient temperatures, suggests that there is no significant enhancement of the slow crack growth rate due to cycling. This is verified in a series of measurements of slow crack growth rates under static and cyclic conditions.     

Monotonic and cyclic damage in metallic sheets

This paper aims to provide an account of some interesting features of damage in metallic sheets under monotonic and cyclic loading using the information and understanding developed through a series of experimental investigations conducted on interstitial free steels. The experiments primarily consisted of damage evaluation in un-notched and notched sheets vis-à-vis that in thick specimens under monotonic loading, and that on sheets by interrupted or continuous cyclic loading. Some salient observations indicate that: (i) void nucleation occurs in two different stages, originating from non-metallic inclusions and precipitates. The critical strain for void nucleation at precipitates (?_c) is lower for sheet metals than that in thick specimens. (ii) ?_c is a function of notch length in sheets, and the function assists to estimate the strength of particle/matrix interface, (iii) under cyclic loading, steel sheets exhibit non propagating microcracks below the endurance limit. Above the endurance limit slip bands promote formation of larger fatigue cracks primarily at ferrite grain boundaries. A series of grain boundary cracks link up to form meso-cracks, one of which grows to cause final failure and (iv) the growth of the macro-crack initially occurs in opening mode followed by its propagation in mixed mode through striations, intergranular cracking and through thickness necking prior to failure.     

Synthesis of lactosyl phosphate diester derivatives of nucleosides

It has been postulated that some arthroscopic shoulder stabilization failures may be due to knot slippage. In an effort to improve arthroscopic technique, we performed tensile testing on four arthroscopically tied knots with two commonly used suture materials. Handtied square knots served as controls. Sutures of No. 1 Maxon and No. 1 Ticron were used. Four types of sliding knot configurations were tested: the overhand loop, the Duncan loop, the Roeder knot, and the Snyder knot. Knots were tied via a knot pusher, and testing was performed in a normal saline-filled thermoplastic chamber. Knots were tied around two rings connected to a Bionix 858 materials testing apparatus. The knots were tested under conditions of cyclic loading and loading to failure. Results of the testing revealed that the most important factor in knot security was the type of suture material, although there were differences with the type of knot. With the Maxon suture, there was significantly decreased ultimate failure load of all of the arthroscopically tied knots compared with handtied square knots. Knots tied with Ticron were similar in strength for both arthroscopically and handtied groups. The surgeon who chooses a monofilament absorbable suture should be aware that a high percentage of knots fail under low load cyclic testing, and that all of these knots were inferior to handtied square knot controls in testing to failure.     

Effects of Principal Stress Rotation on Permanent Deformation in Rail Track Foundations

A realistic assessment of the whole life cost of rail track foundations requires analysis of the effects of the repeated loadings applied by trains. This paper reports the effects of principal stress rotation (PSR) during cyclic loading on the permanent deformations measured in a series of hollow cylinder tests. The tests were carried out on a number of reconstituted soils selected in order to simulate foundation materials on an existing heavy haul railway line. Typical loadings and track geometry together with dynamic finite-element analyses were used to define representative stress changes to be applied to these soils, which were then tested with and without principal stress rotation during loading. It is shown that principal stress rotation has a significant and deleterious impact on permanent deformation of some materials. Therefore, it is concluded that cyclic triaxial testing, which cannot impose principal stress rotation, will not necessarily give good estimates of the long-term performance of rail track foundations. As PSR cannot be ignored when evaluating permanent displacements of rail track foundations, the use of more appropriate (realistic) testing methods such as the cyclic hollow cylinder or the cyclic simple shear apparatus is required.     

Cyclic deformation behavior and microstructures of hydrided ZIRCALOY-4 under biaxial loading

Biaxial fatigue behavior of hydrided ZIRCALOY-4 (Zr-4) in the as-cold-worked (CW) and recrystallized (RZ) conditions under in-phase (IP) and out-of-phase (OP) cyclic loading was investigated. The CW Zr-4 showed cyclic softening followed by a saturation stage during biaxial cyclic loading. Additional cyclic softening was displayed in CW Zr-4 under OP loading with the phase lag of 30 and 60 deg. The additional softening level decreased as the phase lag increased. On the other hand, RZ Zr-4 showed cyclic hardening followed by a saturation stage, and additional cyclic hardening was obtained under OP loading. The additional hardening arose as the phase lag increased. Observation of the fracture surface showed that the biaxial fatigue failure of the CW Zr-4 under OP loading was controlled by crack initiation and propagation through the hydrides, while the nucleation and coalescence of microvoids were dominant in the failure of CW Zr-4 under IP loading and RZ Zr-4 under both IP and OP loading. The typical deformation substructure in CW Zr-4 specimens was composed of dislocation tangles together with parallel dislocation lines under IP and OP loading. Whereas the parallel dislocation lines were formed by prismatic slip for RZ Zr-4 under IP loading and OP loading with the lower phase lag, they developed into dislocation networks, loops, and debris as the phase lag increased under OP loading. The additional cyclic softening for CW Zr-4 was due to the relief of the anisotropic hardening mechanisms when the loading mode changed from IP to OP. The additional cyclic hardening of RZ Zr-4 under OP loading is attributed to an increase in the interaction between the primary dislocations and other dislocations from different slip systems.