燕麦米对肥胖小鼠减肥降脂作用的研究

为了验证燕麦米的减肥降脂功能,以50只昆明种小鼠为试验动物,饲喂高脂饲料构建高脂模型后,分别饲喂含有10%、20%、40%燕麦米饲料,普通饲料组和高脂饲料组为对照组和模型组。测定相关指标的变化情况,得出以下结论:与高脂组相比,肥胖小鼠在食用燕麦米饲料后,饮食、饮水、排泄、体重增加量、Lee’s指数显著降低(P<0.05);血糖与总胆固醇(TC)、低密度脂蛋白浓度(LDL-C)均有所降低(P>0.05);胰岛素含量、胰岛素敏感性指数(IAI)显著升高,胰岛素抵抗(IR)显著降低(P<0.05);小鼠的肝系数、肝脏三酰甘油含量以及脂肪系数显著降低(P<0.05),肝脏的组织切片结果表明,燕麦米能明显降低肝脏的脂肪变性。不同添加量燕麦米组相比,中燕麦米组的体重、Lee’s、TC、TG、LDL-C、脂肪系数、肝系数最低;HDL-C、IAI最高;肝脏脂肪变性基本得到抑制。因此,燕麦米添加量为20%时,减肥效果最明显。     

胍基乙酸对建鲤生产性能、体成分及肌肉能量代谢关键酶的影响

研究胍基乙酸(guanidinoacetic acid,GAA)对建鲤生产性能、体成分及肌肉能量代谢的影响。选取600尾平均体重为(23.23±0.14)g的建鲤随机分为4组,每组5个重复,每个重复30尾,分别投喂基础饲料(对照组)和在基础饲料中添加250、500和1 000 mg/kg GAA的试验饲料,试验为期42 d。结果表明:与对照组相比,添加250、500 mg/kg GAA可显著降低饵料系数(P0.05),但对体重、特定生长率、增重率、平均日采食量和成活率均无显著影响(P0.05)。添加GAA可显著提高脏体指数(P0.05),对肝体指数无显著影响(P0.05)。GAA对肌肉中粗脂肪、粗蛋白和粗灰分含量无显著影响(P0.05)。250 mg/kg GAA组可显著降低肌肉中丙酮酸激酶活性(P0.05);250、500 mg/kg GAA组显著降低琥珀酸脱氢酶活性(P0.05);1 000 mg/kg GAA组显著降低肌酸激酶活性(P0.05);GAA组均显著提高肌糖原含量(P0.05)。结果表明,饲料中添加胍基乙酸可降低肌肉中能量代谢关键酶的活性来改善其能量代谢,提高饲料转化率,以添加250 mg/kg GAA效果较好。     

柠檬酸甘薯淀粉酯对齐口裂腹鱼肉品质的影响

目的：研究柠檬酸甘薯淀粉酯（citric acid-modified sweet potato starch,CSPS）对齐口裂腹鱼肉品质的影响。方法：将240 条体质量75 g左右的齐口裂腹鱼随机分为5 组,每组48 条。饲喂60 d,随机取每个池中8 条鱼测定齐口裂腹鱼鱼肉的品质指标。结果：齐口裂腹鱼饲料中CSPS添加量为14%和28%时能显著降低肌肉中脂肪含量（P＜0.05）;CSPS添加量为3.5%时能显著提高肌肉pH值,添加量为14%时可显著降低肌肉pH值（P＜0.05）;齐口裂腹鱼饲料中添加CSPS对鱼肌肉的蛋白质、灰分、水分、羟脯氨酸和胶原蛋白含量及失水率无显著影响（P＞0.05）;饲料中CSPS添加量为7%和14%时能够显著提高齐口裂腹鱼肌肉的硬度（P＜0.05）;CSPS添加量为28%时能够显著增加肌肉的黏附性（P＜0.05）;与对照组相比,CSPS添加量为14%时能够显著提高肌肉的胶着度（P＜0.05）;CSPS添加量为7%和14%能显著提高肌肉的咀嚼性（P＜0.05）;CSPS对齐口裂腹鱼肌肉的弹性、凝聚性和回复性无显著影响（P＞0.05）。结论：饲料中添加14%的CSPS能够降低齐口裂腹鱼肌肉中脂肪含量,提高肌肉的硬度、黏附性、胶着度和咀嚼性和肉质紧实度,改善鱼肉品质。     

蛹拟青霉发酵菌丝体对青脚土杂肉鸡屠宰性能和肌肉品质的影响

以青脚土杂肉鸡为试验对象,研究了蛹拟青霉液体发酵菌丝体作为饲料添加剂对肉鸡屠宰性能和肌肉品质的影响。结果表明:肉鸡日粮中添加0.25%和0.50%的蛹拟青霉菌丝体时,能显著提高肉鸡的活体重、肌肉中氨基酸、呈味氨基酸的含量,同时也显著提高了肉鸡胸肌肌间脂肪的含量(P<0.05),降低了肌肉的失水率(P<0.05)。但是日粮中添加蛹拟青霉菌丝体对肉鸡的屠宰性能未构成显著性影响。日粮添加蛹拟青霉菌丝体不影响肉鸡的屠宰性能,但可显著改善肉鸡的肌肉品质。     

苦杏仁对肉鸡生长性能和肉品质及肝脏抗氧化能力的影响

通过在肉鸡饲料中添加不同剂量的苦杏仁粉,评价其对肉鸡生长性能、肉品质及肝脏抗氧化能力的影响,探究苦杏仁在畜禽生产中应用及最适添加量,为饲料中抗营养因子的开发利用提供试验依据。试验将100只1日龄AA肉鸡,随机分为4组,每组25只;对照组(C组)饲喂基础全价饲料,低剂量组(L组)饲喂含4.5 g/kg苦杏仁粉的基础全价饲料,中剂量组(M组)饲喂含9 g/kg苦杏仁粉的基础全价饲料,高剂量组(H组)饲喂含17 g/kg苦杏仁粉的基础全价饲料,试验周期为45 d。结果表明,与C组相比,H组肉鸡的终末体重和平均日增重极显著降低(P<0.01),料重比极显著升高(P<0.01),而L组、M组肉鸡的末体重和平均日增重及料重比无显著差异(P>0.05);肌肉放置24 h和48 h后,H组肌肉肉色显著降低(P<0.05),肌肉剪切力极显著增加(P<0.01);L组胸肌粗蛋白质含量显著升高(P<0.05),M组、L组差异不显著(P>0.05)。饲料中添加不同剂量的苦杏仁粉均增强肉鸡肝脏中SOD、CAT和GSH-PX的活性(P<0.05)。试验说明,饲料中添加的低剂量(4.5 g/kg)和中剂量(9 g/kg)苦杏仁粉均可改善肉鸡肉品质和增强肝脏抗氧化性能,其中以添加9 g/kg苦杏仁的效果最佳。而添加高剂量(17 g/kg)的苦杏仁粉虽能增强肉鸡肝脏的抗氧化能力,但会导致肉鸡的生长性能和肉品质降低。     

牛磺酸对大鼠的减重降脂作用

目的:探讨牛磺酸饮水对高脂血症大鼠减重降脂的作用。方法:根据血清总胆固醇(TC)和体重将SD大鼠随机分为对照组、高脂模型组和牛磺酸(低、高)剂量组。对照组摄食普通饲料,其余三组摄食高脂饲料,牛磺酸组饮用牛磺酸水溶液。饲养12周后处死动物,检测血清TC、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、甘油三酯(TG)水平,血清谷胱甘肽过氧化物酶(GSH-PX)和超氧化物歧化酶(SOD)活力;粪便中总胆汁酸(TBA)含量;肝脏TC、TG、游离脂肪酸(FFA)、还原型谷胱甘肽(GSH)、肝糖原的含量和GSH-PX酶活力。结果:高剂量牛磺酸显著降低高脂饮食大鼠的体重,两个剂量牛磺酸都可以显著降低大鼠附睾脂肪垫指数;高剂量牛磺酸显著降低大鼠血清TC、LDL-C、肝脏FFA和肝糖原水平,两个剂量牛磺酸对肝脏TC和TG均无显著影响,但都可显著增加粪便TBA含量;两个剂量牛磺酸都可以显著升高大鼠血清GSH-PX和肝脏GSH-PX、还原型GSH。结论:牛磺酸主要通过促进胆固醇转化为胆汁酸,并随粪便排出、加强脂质代谢减少肝脏FFA堆积、提高机体抗氧化能力等途径发挥减重降脂功效,但其减重降脂机制还需深入研究。     

不同棉粕和向日葵仁粕对草鱼生长、鱼体组成的影响

在相同条件下定量比较普通棉粕、高蛋白棉粕、棉籽蛋白和向日葵仁粕4种植物蛋白原料,以及硬颗粒与挤压膨化两种加工工艺对草鱼生长速度、饲料效率、形体、内脏指数及鱼体组成的影响。试验设计蛋白水平(29%)和脂肪水平(3.5%)基本一致的条件,同种原料分别设计低剂量和高剂量两个用量水平,并且相同配方下同时进行硬颗粒和挤压膨化两种加工处理的试验,共16个试验饲料组,于室内水泥池的网箱中喂养平均体重(39.4±1.8)g的草鱼56 d。结果表明:(1)4种植物蛋白原料对草鱼的特定增长率、内脏比、脾体比以及鱼体组成的影响都有显著性差异(P<0.05),而草鱼的饲料系数、蛋白质效率、体重体长比以及肝体比之间差异不显著(P>0.05);(2)同种原料的2种添加剂量对草鱼的特定增长率、饲料系数、蛋白质效率和形体指标的影响都没有显著性差异(P>0.05),但草鱼全鱼和肌肉的粗蛋白及粗脂肪含量差异显著(P<0.05);(3)采用不同的饲料加工工艺,草鱼的饲料系数、蛋白质效率、体重体长比、肾体比、脾体比,以及全鱼、肌肉、肝胰脏的粗蛋白和粗脂肪含量的差异均达到显著水平,而草鱼的特定增长率和肝体比差异不显著(P>0.05)。由此得出:草鱼日粮饲料配方中添加普通棉粕、向日葵仁粕、高蛋白棉粕和棉籽蛋白4种植物蛋白原料时,饲料利用率较高,能够取得良好的养殖效果;4种植物蛋白原料添加量分别控制在22%～32%、20%～28%、18.5%～26.5%、15.5%～22.5%之间为宜,在此添加量范围内,4种蛋白原料对草鱼生长的差异不显著性(P>0.05);硬颗粒饲料比膨化颗粒饲料更利于草鱼的生长及提高饲料的利用率。     

桑叶饲料添加剂对鸡蛋黄品质的影响

分析在蛋鸡饲料中分别添加2.5%、5.0%、7.5%、10.0%桑叶对鸡蛋黄品质的影响,结果表明：随桑叶添加量增加,蛋黄颜色加深;添加桑叶对蛋黄胆固醇含量影响不大;5.0%和7.5%桑叶组的蛋黄磷含量显著高于对照组(P＜0.05);添加桑叶各组的饱和脂肪酸含量比对照组显著降低(P＜0.05),单不饱和脂肪酸与多不饱和脂肪酸含量比对照组极显著提高(P＜0.01);5.0%和7.5%桑叶组的7种必需氨基酸总量显著高于对照组(P＜0.05);蛋黄VE含量随桑叶添加量增加而极显著增加(P＜0.01),其中10.0%桑叶组比对照组提高了近3倍。桑叶组蛋黄在气味和口感上都优于对照组,其中5.0%、7.5%桑叶组较其他桑叶组好(P＜0.05)。总之,饲料中添加桑叶能改善鸡蛋黄的品质,添加量在5.0%～7.5%比较合适。     

饱和脂肪酸对泌乳中期热应激奶牛产奶性能、采食量和能量代谢的影响

研究饱和脂肪酸对泌乳中期热应激奶牛产奶性能、采食量和能量代谢的影响。选择产后150~210 d的中国荷斯坦奶牛48头,采用完全随机区组试验设计,根据产奶量、分娩时间和胎次分为对照组、1.5%和3%饱和脂肪酸试验组。试验期间牛舍最小湿热指数(THI)在72以上。结果显示,日粮添加饱和脂肪酸显著提高奶牛产奶量(P0.05),1.5%与3%脂肪组之间差异不显著;乳脂和总固体产量,3%脂肪组显著高于1.5%脂肪组和对照组(P0.05),1.5%脂肪组显著高于对照组(P0.05)。饱和脂肪酸对DMI无影响,净能和粗脂肪采食量随脂肪添加量而呈线性增加(P0.01)。3%和1.5%脂肪组分别比对照组净能转化率提高5.69%和6.04%;粗蛋白转化率分别提高8.48%和6.20%,体重和体况三组间无差异。血液中NEFA含量,3%脂肪组显著低于对照组(P0.05);血糖、胆固醇、BHBA、胰岛素三组间无差异。饱和脂肪酸可以提高奶牛产奶性能和维持能量平衡,对能量代谢、采食量、体重和体况无明显影响。     

鲤鱼肉蛋白水解物在熟猪肉糜中的抗氧化效果

研究鲤鱼肉蛋白的碱性蛋白酶(alcalase)水解物对肉糜的抗氧化作用。将肉糜分为6组,包括阴性对照组、2.0%的未水解鲤鱼肉蛋白组、1.0%、1.5%、2.0%的水解物(4h)添加组、0.02%的丁基羟基茴香醚(butylatedhydroxyanisole,BHA)的阳性对照,在冷藏7d过程中测定肉糜的红度值(a*)、硫代巴比妥酸值(TBARS)值和pH值的变化,并对产品的感官指标进行评定。结果表明:与对照组相比,添加水解物的处理组能显著抑制脂肪的氧化(P<0.05),其中2.0%水解物处理组效果最明显,能显著降低TBARS值、增加肉糜的红度值(a*)(P<0.05),但较添加BHA处理组的效果欠佳;感官评定得到同样的结果。     

Taurine is Involved in Energy Metabolism in Muscles,Adipose Tissue,and the Liver

Energy metabolism is a basic and general process, by which the body acquires and uses energy to maintain normal function, and taurine plays a vital role in energy metabolism. Taurine deficiency may cause a weak energy metabolism and energy metabolism dysfunction. Taurine biosynthetic ability is limited, and its supplementation in the diet can strengthen energy metabolism in muscle performance, cardiac function, liver activity, and adipose tissue. Combining taurine with other drugs may have a superior effect in energy metabolism. In many metabolic disorders, taurine, or the combination of taurine with other drugs, also functions as a repair treatment for damaged tissues, and acts as a promoter for the balance of energy metabolism. The present study discusses the potential roles of taurine in energy metabolism.     

牛磺酸对鹌鹑产蛋性能、脂肪代谢及免疫功能的影响

以鹌鹑为研究对象,在日粮中添加不同剂量的牛磺酸(Tau),考察Tau对鹌鹑产蛋性能、脂肪代谢及免疫功能的影响。将108只鹌鹑分为3个处理组,每个处理组4个重复,每个重复9只,进行试验4周。结果表明,添加质量分数为0.01%Tau显著降低破蛋率,添加质量分数为0.05%Tau显著提高产蛋率,显著降低料蛋比和破蛋率(P0.05);0.05%Tau组显著提高免疫球蛋白(IgG)含量和增强皮肤超敏反应(FWI)(P0.05);质量分数0.01%Tau显著降低动脉硬化指数(AI)和甘油三酯(TG)含量;质量分数0.05%Tau组可显著提高血清高密度脂蛋白(HDL-C)含量和脂蛋白酯酶(LPL)活性,显著降低TG含量和AI指数(P0.05)。结果提示,日粮中添加牛磺酸可提高鹌鹑的产蛋率和有效降低软破蛋率,牛磺酸提高了鹌鹑的免疫功能,通过提高血清LPL活性和HDL-C水平促进了脂肪代谢。     

牛磺酸对鹌鹑生产性能、免疫功能及抗氧化能力的影响

以鹌鹑为研究对象,于日粮中添加不同剂量(0,100,500 mg/kg)的牛磺酸(Tau),考察Tau对鹌鹑生产性能、免疫功能及抗氧化能力的影响.将300只1日龄鹌鹑分为3个处理组,每个处理组4个重复,每个重复25只,试验6周.结果表明,添加500 mg/kgTau可显著增加鹌鹑0～3 w体增重和3周龄体重,显著降低0～3、3～6、0～6 w的料重比(P＜0.05).Tau可显著增加鹌鹑外周血B淋巴细胞增殖能力,500 mg/kgTau可显著增加T淋巴细胞增殖能力(P＜0.05).Tau 可显著提高血清免疫球蛋白IgG质量浓度(P＜0.05).添加100 mg/kg Tau可显著提高鹌鹑血清总抗氧化能力,减少血清丙二醛的产生(P＜0.05).结果显示,日粮中添加牛磺酸可提高鹌鹑的生产性能,通过提高机体的淋巴细胞增殖能力和血清IgG含量增强鹌鹑的免疫功能,牛磺酸可提高鹌鹑的抗氧化能力.     

Dietary taurine reduces zinc-induced toxicity in male Wistar rats

Taurine is an agent for treating the heavy metal intoxication and presence of metals such as zinc, copper, and iron may have a role in heavy metal toxicity, a study was undertaken to investigate the effect of taurine on the toxicity of zinc in male Wistar rats. The rats were divided into 8 groups and fed different diets with or without supplement of 5% taurine and 150 to 600 ppm zinc for 2 mo. It was found that the body weight of rats, the ratios of liver and kidney weight to body weight, and the level of glutathione in the liver were decreased with increasing the dose of zinc. The levels of zinc in the liver, kidney, and plasma, the levels of malondialdehyde in the plasma, the levels of thiobarbiture acid-reactive substances in the liver, the activities of aspartate transaminase, alanine transaminase in the plasma, the levels of blood urea nitrogen and creatinine in the plasma of rats were increased with the increasing dose of zinc. Hence, symptoms of zinc toxicity in rats included loss of body weight, hepatotoxicity, and nephrotoxicity. However, these toxic effects of zinc were significantly reduced when the rats fed diet with supplement of taurine. Furthermore, the level of zinc in the feces of rats treated with taurine and zinc was higher than that of rats treated with zinc alone. It indicated that taurine thereby leading to a decreased absorption of dietary zinc and promoted excretion.     

Protective effects of taurine against hepatic abnormality in NZB/W F1 mice fed a hypercholesterolemic diet

A hypercholesterolemic diet has been associated with the hepatic abnormalities and the pathological processes of systemic lupus erythematosus (SLE). To investigate the effects of taurine on the hepatic abnormality in SLE, NZB/W F1 mice were used as an animal model by receiving control, cholesterol, or cholesterol + taurine diets, respectively. Reductions (P < 0.05) of liver-to-body weight ratio, lipid deposit, mean arterial pressure, serum total cholesterol (TC), triacylglycerol (TAG), AST, ALT and hepatic CRP levels were detected in the cholesterol + taurine group as compared to those of the cholesterol group. In addition, stress-related molecules in livers, including HSP70, HSP90, MMP9 and iNOS, were also lower (P < 0.05) in the cholesterol + taurine group compared to the cholesterol group. These findings demonstrated the protective effects of taurine on the hepatic abnormality in NZB/W F1 mice fed a hypercholesterolemic diet and may suggest taurine as a dietary supplementation for SLE patients.     

亚麻籽和茶多酚对肉鸭生长性能、屠宰性能、血液抗氧化能力和肌肉不饱和脂肪酸含量的影响

研究以亚麻籽为n-3 PUFA来源的肉鸭饲粮中添加茶多酚(TP),对其生长性能、屠宰性能、抗氧化能力和肌肉不饱和脂肪酸含量的影响。选用240只1日龄樱桃谷肉鸭,随机分为4组,其中对照组饲喂基础饲粮,实验组一、二、三分别饲喂含3%亚麻籽、3%亚麻籽+100 mg/kg TP、3%亚麻籽+200 mg/kg TP的实验饲粮。实验期为40d。结果表明:实验组一的平均日采食量(ADFI)和料重比(F/G)显著高于对照组(P 0.05);实验组二、三的ADFI和F/G与对照组差异不显著(P 0. 05)。屠宰率、半净膛率和全净膛率各组间均差异不显著(P 0. 05)。实验组三血浆的总抗氧化能力(T-AOC)、总超氧化物歧化酶(T-SOD)活力显著高于对照组(P 0. 01),丙二醛(MDA)含量显著低于对照组(P 0. 01)。各实验组腿肌中n-3 PUFA的含量均显著高于对照组(P 0. 05)。因此,饲粮中添加3%亚麻籽会显著增加樱桃谷肉鸭的料重比,以及肌肉中n-3PUFA的含量,但对屠宰性能无显著影响。在肉鸭饲粮中添加3%亚麻籽用于生产富含n-3 PUFA肉产品时加入200 mg/kg TP对肉鸭生长性能及机体抗氧化效果最佳。     

纳米甘薯渣纤维素对糖尿病大鼠血糖及血脂水平的影响

目的：探讨纳米甘薯渣纤维素对糖尿病大鼠血糖及血脂的影响。方法：选用40 只雄性Sprague-Dawley（SD）大鼠随机分组为5 组,其中1 组大鼠喂食基础饲料作为空白组,另外4 组采用链脲佐菌素（streptozotocin,STZ）诱导大鼠建立糖尿病模型,分为模型对照组（MC组）、普通甘薯渣纤维素组（OC组）、微晶甘薯渣纤维素组（MCC组）和纳米甘薯渣纤维素组（CNC组）,实验期28 d,测定大鼠体质量、采食量、空腹血糖、糖化血清蛋白、血清胰岛素、肝糖原及血脂水平等指标。结果：模型对照组大鼠的采食量,空腹血糖、糖化血清蛋白、血脂水平均显著高于空白组（P＜0.05）,体质量、胰岛素和肝糖原含量明显下降（P＜0.05）,说明造模成功,糖尿病大鼠表现出相应的症状。喂食不同粒度甘薯渣纤维素的糖尿病大鼠,其体质量、血清胰岛素和肝糖原水平有所增加,而空腹血糖、糖化血清蛋白、血脂水平等都有所下降,其中喂食纳米甘薯纤维素的糖尿病大鼠指标变化具有显著性差异（P＜0.05）。结论：从甘薯渣纤维素粒度分析,可以看出随着甘薯渣纤维素粒度的减小,其对糖尿病大鼠血糖血脂的调节作用愈加明显,其中纳米甘薯渣纤维素具有较好的调节血糖血脂水平的作用。     

Dietary Tryptophan Enhanced the Expression of Tight Junction Protein ZO‐1 in Intestine

Dietary amino acids provide various beneficial effects for our health. The aim of the present study was to assess the effects of tryptophan (Trp) supplementation on barrier function. Ninety‐six healthy finishing pigs (initial body weight 51.49 ± 1.12 kg) were randomly allocated into 2 treatment groups, control group, and 0.2% Trp group. The control group was fed the basal diet, and 0.2% Trp group was fed basal diet plus 0.2% Trp. The trial period is 60 d. Compared with control group, the mRNA abundance of claudin‐3 and zonula occluden‐1 (ZO‐1) in the jejunum in 0.2% Trp group (P < 0.05) was increased. According to immunohistochemistry and immunoblotting test, the expression of ZO‐1 in jejunum in 0.2% Trp group was also significantly increased compared with the control group (P < 0.05). These results revealed that Trp enhanced the expression of tight junction protein ZO‐1 in the intestine of pig model. Trp may be potential and beneficial dietary functional factor for regulating the intestinal development and inhibiting intestinal aging.     

Effects of dietary supplementation with antimicrobial peptide‐P5 on growth performance,apparent total tract digestibility,faecal and intestinal microflora and intestinal morphology of weanling pigs

BACKGROUND: The increase in drug‐resistant bacteria and the ban on antibiotic growth promoters worldwide make the search for novel means of preventing bacterial infection and promoting growth performance imperative. In this sense, antimicrobial peptides are thought to be ideal candidates owing to their antimicrobial properties, broad spectrum of activity and low propensity for development of bacterial resistance. The aim of the present study was to investigate the effect of dietary supplementation with antimicrobial peptide‐P5 (AMP‐P5) on weanling pig nutrition. RESULTS: A total of 240 weanling pigs were allotted to four treatments on the basis of initial body weight. There were four replicates in each treatment, with 15 pigs per replicate. Dietary treatments were negative control (NC, basal diet without antimicrobial), positive control (PC, basal diet + 1.5 g kg^?1 apramycin), basal diet with 40 mg kg^?1 AMP‐P5 (P5‐40) and basal diet with 60 mg kg^?1 AMP‐P5 (P5‐60). Pigs fed the PC or P5‐60 diet showed improved (P < 0.05) overall growth performance, apparent total tract digestibility of dry matter, crude protein and gross energy and reduced (P < 0.05) faecal and intestinal coliforms compared with pigs fed the NC diet. CONCLUSION: The results obtained in this study indicate that dietary supplementation with 60 mg kg^?1 AMP‐P5 has the potential to improve the growth performance and apparent total tract digestibility of nutrients and reduce coliforms in weanling pigs. © 2012 Society of Chemical Industry