Clinical examination of visual and social responses in infant rhesus monkeys.

Obtained normative data from a battery of tests (e.g., pupillary response, sound localization, orienting, and face reaction) administered to evaluate simple visual functions in 15 infant rhesus monkeys. Visual responsiveness was limited to simple reflexes in the 1st days of life, but it developed rapidly. By the 2nd wk, Ss reached for objects and responded socially to faces with both gaze aversion and lipsmacking. However, social responsiveness developed differently in males and females: Males responded to faces with lipsmacking 4 days after responding with gaze aversion, while females showed both responses for the 1st time on the same day. (18 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Halasz syndrome revealed in the newborn infant by pulmonary arterial hypertension. Study of 4 cases

In the 4 studied patients presenting with an Halasz's syndrome, the disease was complicated since the neonatal period by pulmonary arterial hypertension and heart failure. Three out of the 4 infants rapidly died, one after pneumonectomy. The fourth is surviving and benefitted solely from medical cardiotonic treatment. The pathogenesis of early pulmonary arterial hypertension in Halasz's syndrome is complex. The possibly associated cardiac malformations, the persistance of fetal obstructive hypertension due to the increase of the flow in the left pulmonary artery, the left to right shunt induced by the abnormal venous return and predominantly by the systemic blood supply to the right lung, are responsible, at various degrees, for pulmonary hypertension. Among surgical procedures to be proposed, the simple ligation of abnormal arteries which take their origin from the aorta seems to be preferable to pneumonectomy.     

Dysentery in the newborn infant

DNA replication in eukaryotic cells is closely associated with protein synthesis. When protein synthesis is specifically inhibited, DNA synthesis stops quickly too. No precise knowledge has been so far available concerning the reasons of this coupling. The data presented confirm an earlier established for Chlorella fact that the inhibition of DNA synthesis in L-cells, due to a several hours treatment with hidroxyurea, results in a consequent stability of DNA synthesis in these cells to a protein synthesis inhibitor--cyclohexamide.     

Balanitis and infectious agents. A prospective study of 100 cases

INTRODUCTION: The aim of this study was: 1) to evaluate the rate of micro-organism isolation in 100 patients consulting for balanitis at the Centre of sexually transmitted diseases at the St. Louis Hospital in Paris in comparison with that of micro-organisms isolated in 60 men without balanitis; 2) to search for a possible correlation between the clinical aspect of the disease and the nature of the infectious agent identified. METHODS: One hundred consecutive patients were included in the study. All underwent a clinical examination and samples were taken for bacteriology, mycology and virology examinations. Sixty healthy volunteers served as controls. Two samples were taken from the balanopreputial groove in search for fungi and bacteria. RESULTS: Candida albicans (CA) was isolated in 33 p. 100 of the patients. A pathogenic bacteria (beta-haemolytic streptococci, Staphylococcus aureus, Klebsiella), or a potentially pathogenic germ (Haemophilus parainfluenzae, anaerobic bacteria, Gardnerella vaginalis, Streptococcus milleri, group HB5) was found without CA in 28 p. 100 of the cases, a commensal flora (enterobacteria, group D streptococci) was found without CA in 8 p. 100 and in 31 p. 100 of the cases non causal agent could be identified. DISCUSSION: This series confirms the non-pathogenic nature of commensal bacteria: the number of isolations was similar in the subjects with and without balanitis (p < 0.9). The role played by the other bacteria in the development of balanitis is discussed: saprophytic association or direct pathogenesis? The significant difference in the rate of bacteria isolations in patients with balanitis compared with controls (p < 0.001) is in favour of a pathogenic role. The clinical presentation was not predictive of the presence of any particular micro-organism excepting the presence of pustules which were highly suggestive of candidiasis.     

婴幼儿牛奶过敏162例临床分析

牛奶过敏(cow's milk allergy)是小儿最常见的食物过敏之一,在欧美发达国家,婴儿牛奶过敏发生率约2%～7.5%.牛奶过敏的婴儿还可能对其它食物过敏,如蛋类、豆类、花生仁等,50%牛奶过敏婴儿以后可能出现对吸人性过敏原,如尘螨、花粉等过敏,同时,牛奶过敏婴儿还存在着发生哮喘、湿疹、过敏性鼻炎等特应性疾病的风险.     

Sepsis in the very low-birth-weight newborn infant

Sepsis is a common pathology during the neonatal period. Low-birth weight is the most important isolated risk factor. With the purpose of determining the prevalence of nosocomial infection in newborns of very low birth weight (VLBW), finding the microbial flora and the mortality of these patients, the authors retrospectively analysed the clinical processes of the hospitalized VLBW in the Neonatal Intensive Care Unit (NICU) in S. Jo?o Hospital in 1993 and 1994. Of the 1091 newborns admitted to the hospital in these two years, 112 were VLBW (10%). Of these, 48 had sepsis-31 (28%) confirmed sepsis and 17 (15%) probable sepsis. The agents most commonly found were Staphylococcus epidermidis (44%) and Klebsiella pneumoniae (21%). Thirteen patients (27%) died, with infection as the cause of death in nine (19%). Our results confirm the importance of nosocomial neonatal infection, which should involve the strict observance of the asepsis norms and a proper policy of antibiotics.     

Predictive value of IGE in the newborn infant

To study the relationship of IgE titles to development of allergy disease in the nursing, it was quantified the levels of this immunoglobulin in blood of the umbilical cord in healthy term eutrofic infants born consecutively in a period of two months. A total of 74 infants were followed for six with monthly appointments. The mean of IgE was 0.08 IU/ml with standard deviation of 0.15. Only two infants developed allergy, this determined a negative predictive value for IgE of 94%. Our outputs agree with that of other authors with respect to high negative predictive value of the low or normal levels of IgE in blood of the umbilical cord and the development of allergy. We concluded that its determination should limit to infants with family antecedent of atopy in order to improve the capacity of prediction of this illness.     

Dynamic study of tissue circulation in the cervix uteri and the prognosis of the newborn infant

A new machine has been developed to measure heat dissipated in the tissues especially by convection linked to the blood flow. Its use is simple and without any danger as far as application to the pregnant cervix goes. New discoveries are presented. A new concept of the micro-circulation is considered together with the consequences. The practitioner may be able to draw conclusions as to the prognosis, as to whether a small-for-dates fetus together with or without premature labour is likely. This depends on the tracings obtained which register the intrinsic activity of the periarteriolar muscles.