Correlation of reactivity with chemical structure: Thermal hydrogenation of gas oils

The relationship between chemical structure and reactivity for thermal hydroprocessing was studied for five gas oils derived from Alberta bitumens. Chemical structure was characterized by combining data from ¹ H and ¹³ C nuclear magnetic resonance spectroscopy, class fractionation, and elemental analysis to calculate structural parameters. Thermal hydrotreating was performed in a continuous-flow stirred reactor at 420 and 440°C, 13.9 MPa hydrogen pressure, and 1.5 h¹ LHSV. Conversion of the 343–525°C boiling fraction of the gas oils was correlated with the concentration of naphthenic methylene groups in the feed. Formation of methane and ethane was dependent on the degree of condensation of the aromatic rings in the feed oils. Thermal desulfurization was highly correlated with the amount of saturates in the feed, and the aromaticity of the resin fraction. Hydrogen consumption increased with the aromaticity of the gas oil…     

Oxy210, a Semi-Synthetic Oxysterol,Exerts Anti-Inflammatory Effects in Macrophages via Inhibition of Toll-like Receptor (TLR) 4 and TLR2 Signaling and Modulation of Macrophage Polarization

Inflammatory responses by the innate and adaptive immune systems protect against infections and are essential to health and survival. Many diseases including atherosclerosis, osteoarthritis, rheumatoid arthritis, psoriasis, and obesity involve persistent chronic inflammation. Currently available anti-inflammatory agents, including non-steroidal anti-inflammatory drugs, steroids, and biologics, are often unsafe for chronic use due to adverse effects. The development of effective non-toxic anti-inflammatory agents for chronic use remains an important research arena. We previously reported that oral administration of Oxy210, a semi-synthetic oxysterol, ameliorates non-alcoholic steatohepatitis (NASH) induced by a high-fat diet in APOE*3-Leiden.CETP humanized mouse model of NASH and inhibits expression of hepatic and circulating levels of inflammatory cytokines. Here, we show that Oxy210 also inhibits diet-induced white adipose tissue inflammation in APOE*3-Leiden.CETP mice, evidenced by the inhibition of adipose tissue expression of IL-6, MCP-1, and CD68 macrophage marker. Oxy210 and related analogs exhibit anti-inflammatory effects in macrophages treated with lipopolysaccharide in vitro, mediated through inhibition of toll-like receptor 4 (TLR4), TLR2, and AP-1 signaling, independent of cyclooxygenase enzymes or steroid receptors. The anti-inflammatory effects of Oxy210 are correlated with the inhibition of macrophage polarization. We propose that Oxy210 and its structural analogs may be attractive candidates for future therapeutic development for targeting inflammatory diseases.     

A collaborative platform for buyer coalition: Introducing the Awareness-based Buyer Coalition (ABC) system

A variety of buyer coalition schemes already exist in the current e-Commerce literature by which buyers form some sort of coalition in order to enjoy added discounts as a result of purchasing in larger bundles. One major problem in all existing schemes is that none of those schemes explicitly treat the coalition process as a collaborative business process; and as a result, the awareness and knowledge-sharing requirements are not explicitly recognized in the design process of the existing systems. This study proposes a conceptual framework for a buyer coalition system called the Awareness-based Buyer Coalition (ABC) system that allows a buyer to bid on the basis of various levels of awareness that s/he may have about other roles’ actions/intentions. The study is an early attempt for explicitly considering awareness and knowledge-sharing requirements of various roles within the buyer coalition process. The theoretical foundations of the study are rooted in the fields of Game Theory, e-Commerce, and Knowledge Management. The research methodology adopted for the study is design science. Various existing buyer coalition algorithms were reviewed and their strengths and weaknesses identified in terms of addressing the information-sharing needs of collaborating buyers. Furthermore, the existing literature on Knowledge Management was reviewed in order to identify an appropriate process model for the proposed buyer coalition framework with specific emphasis on awareness and knowledge-sharing requirements of its collaborating actors. For validation of the proposed conceptual model simulation software was developed to demonstrate results of a variety of simulations for the proof of the concept.     

Quantitative characterization of carrier injection across metal–organic interfaces using Bardeen theory

We have investigated the contact between a metal and an organic/polymeric (o/p) material and we have introduced a relation for carrier injection using Bardeen theory. A series of narrow barriers is considered in the semiconductor side to account for the localized nature of the carriers in the o/p material. As an application of the model, we have calculated the hopping rate of carriers in terms of the contact parameters. Also, we have discussed the hopping of carriers deep into the organic dielectric. Finally, we have explored the hopping rate in practical contacts between polyfluorene-based polymers and different electrodes.     

A wrapper‐based feature selection for improving performance of intrusion detection systems

Along with expansion in using of Internet and computer networks, the privacy, integrity, and access to digital resources have been faced with permanent risks. Due to the unpredictable behavior of network, the nonlinear nature of intrusion attempts, and the vast number of features in the problem environment, intrusion detection system (IDS) is regarded as the main problem in the security of computer networks. A feature selection technique helps to reduce complexity in terms of both the executive load and the storage by selecting the optimal subset of features. The purpose of this study is to identify important and key features in building an IDS. To improve the performance of IDS, this paper proposes an IDS that its features are optimally selected using a new hybrid method based on fruit fly algorithm (FFA) and ant lion optimizer (ALO) algorithm. The simulation results on the dataset KDD Cup99, NSL‐KDD, and UNSW‐NB15 have shown that the FFA–ALO has an acceptable performance according to the evaluation criteria such as accuracy and sensitivity than previous approaches.     

Fault detection in analogue circuits using hybrid evolutionary algorithm and neural network

With the development of analog integrated circuits technology and due to the complexity, and various types of faults that occur in analog integrated circuits, fault detection is a new idea, has been studied in recent decades. In this paper a three amplifier state variable filter is used as circuit under test (CUT) and, a hybrid neural network is proposed for soft fault diagnosis of the CUT. Genetic algorithm (GA) has the powerful ability of searching the global optimal solution, and back propagation (BP) algorithm has the feature of rapid convergence on the local optima. The hybrid of two algorithm will improve the evolving speed of neural network. GA-BP scheme adopts GA to search the optimal combination of weights in the solution space, and then uses BP algorithm to obtain the accurate optimal solution quickly. Experiment results show that the proposed GA-BP scheme is more efficient and effective than BP algorithm.     

Low-voltage and low-power Ku-band CMOS LNA using capacitive feedback

Analog Integrated Circuits and Signal Processing - An ultra-wideband (12–18 GHz) low-noise amplifier (LNA) using a 65 nm CMOS technology is proposed, in which a...     

A Distance Based Communication Mode Selection Mechanism for M2M Communications Over Cellular Networks

The implementation of machine-to-machine (M2M) communications in fifth-generation (5G) cellular networks can facilitate with several benefits like enhancement of bandwidth utilization, accommodating large number of users and decreasing traffic load on evolved node B (eNB). Integration of location information of unknown machine in communication mode selection mechanism is the key feature of this research. In this paper, a distance based communication mode selection mechanism using non-orthogonal resource sharing scheme is adopted in the proposed system model. Under the proposed mechanism, the expressions of throughput and RBs utilization policy are derived, which are the key parameters to evaluate the performance in the proposed network. Depending on the mode selection condition, such as threshold distance and threshold SINR between M2M users and regular cellular users, a UE can automatically choose its communication mode in the network. It is supposed that selection of mode before data transfer can improve the system performance. On the other hand, designing of efficient distance assisted proposed resource blocks (RBs) utilization policy reduces the traffic load on the eNB. Extensive simulations are carried out for evaluating the performance of the proposed mechanisms. The system performance is compared with various changeable parameters, such as throughput, mode selection threshold SINR, threshold distance and RBs. Besides, the proposed mechanism provides better network performance as well as reduces the traffic load in the proposed network.

     

All-optical 6- and 8-channel demultiplexers based on photonic crystal multilayer ring resonators in Si/C rods

In this paper, we employed multilayer ring resonators in a silicon rod base structure to realize 6-channel and 8-channel demultiplexers based on two-dimensional photonic crystals. Both the main rings and basic structures are composed of silicon rods, and the interior rings of the multilayer rings are composed of carbon. Employing silicon and carbon rods of different radii in multilayer ring resonators enhanced the coupling efficiency between the rings and waveguides. The average quality factor and power transmission efficiency were 4320 and 93%, respectively. Crosstalk values from \(-11\) to ?46 dB in conjunction with the mentioned characteristics suggest the use of the device for optical communication applications. The compact size of the proposed structure and the materials used make the proposed demultiplexer suitable for optical integrated circuits.     

Design of bandpass–bandpass diplexers using rectangular-, T-, and L-shaped resonators for hybrid power amplifier and 5G applications

Analog Integrated Circuits and Signal Processing - In this paper, two bandpass–bandpass diplexers, based on L-, T- and rectangular-shaped resonators are designed and analyzed, which are used...