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排序方式: 共有290条查询结果,搜索用时 31 毫秒
1.
Ludger Brühl 《European Journal of Lipid Science and Technology》1996,98(11):380-383
The adulteration of cold pressed oils (CPO) by refining or by blending with refined oils leads to an increase in their trans fatty acid (TFA) contents. The regulations of the European Union (EU) lay down strict processing conditions without any steam treatment for native olive oils and provide limits for TFA. However, German regulations allow a “steam washing” for CPO other than native olive oil and do not limit TFA. Thus, the TFA contents of such oils might exceed the limits for native olive oil. Modern capillary GLC serves as a quick tool for the detection of TFA. However, care should be taken to avoid the formation of TFA as artefacts during analysis. We evaluated the TFA contents in several oils labelled as “cold pressed” and the formation of TFA during “steam washing” and deodorization. Analysis of some seeds indicates that preliminary drying of the seeds may also contribute to TFA content. 相似文献
2.
Michael Hausmann Martin Falk Charlotte Neitzel Andreas Hofmann Abin Biswas Theresa Gier Iva Falkova Dieter W. Heermann Georg Hildenbrand 《International journal of molecular sciences》2021,22(7)
In cancer therapy, the application of (fractionated) harsh radiation treatment is state of the art for many types of tumors. However, ionizing radiation is a “double-edged sword”—it can kill the tumor but can also promote the selection of radioresistant tumor cell clones or even initiate carcinogenesis in the normal irradiated tissue. Individualized radiotherapy would reduce these risks and boost the treatment, but its development requires a deep understanding of DNA damage and repair processes and the corresponding control mechanisms. DNA double strand breaks (DSBs) and their repair play a critical role in the cellular response to radiation. In previous years, it has become apparent that, beyond genetic and epigenetic determinants, the structural aspects of damaged chromatin (i.e., not only of DSBs themselves but also of the whole damage-surrounding chromatin domains) form another layer of complex DSB regulation. In the present article, we summarize the application of super-resolution single molecule localization microscopy (SMLM) for investigations of these structural aspects with emphasis on the relationship between the nano-architecture of radiation-induced repair foci (IRIFs), represented here by γH2AX foci, and their chromatin environment. Using irradiated HeLa cell cultures as an example, we show repair-dependent rearrangements of damaged chromatin and analyze the architecture of γH2AX repair clusters according to topological similarities. Although HeLa cells are known to have highly aberrant genomes, the topological similarity of γH2AX was high, indicating a functional, presumptively genome type-independent relevance of structural aspects in DSB repair. Remarkably, nano-scaled chromatin rearrangements during repair depended both on the chromatin domain type and the treatment. Based on these results, we demonstrate how the nano-architecture and topology of IRIFs and chromatin can be determined, point to the methodological relevance of SMLM, and discuss the consequences of the observed phenomena for the DSB repair network regulation or, for instance, radiation treatment outcomes. 相似文献
3.
Bronson D. Hausmann Emily M. Aaldenberg Minoru Tomozawa 《Journal of the American Ceramic Society》2021,104(7):3087-3096
Silica glass samples were given various heat treatments under stress at low temperatures and subsequently their residual stress distributions in terms of retardance were observed using a polarized light microscope, confirming previously reported fast surface stress relaxation while providing more detailed characterization. Retardance profiles of silica glass fibers heat-treated under a constant bending strain in the presence of atmospheric water vapor were measured and fit to a previously developed diffusion-based relaxation model. The retardance of a cross-section of a silica glass rod heat-treated at 650°C in lab air under applied torsional shear strain was also measured to confirm the presence of residual surface shear stress which was predicted by the decrease of torque with time for the rod. Together, these results confirm the low-temperature fast surface stress relaxation which occurs when water vapor is present for both bending and shear stresses. 相似文献
4.
Bernhard Esslinger Ludger Schmidt Benjamin Strenge Arno Wacker 《Datenschutz und Datensicherheit - DuD》2016,40(5):283-289
E-Mail-Verschlüsselung könnte längst flächendeckend Verwendung finden. Der Beitrag gibt eine Antwort auf die Frage, warum dies nicht der Fall ist–und macht Vorschläge, was getan werden sollte, um dies zu ändern. 相似文献
5.
Nesterov A König K Felgenhauer T Lindenstruth V Trunk U Fernandez S Hausmann M Bischoff FR Breitling F Stadler V 《The Review of scientific instruments》2008,79(3):035106
We examined the high precision deposition of toner and polymer microparticles with a typical size of approximately 10 microm on electrode arrays with electrodes of 100 microm and below using custom-made microelectronic chips. Selective desorption of redundant particles was employed to obtain a given particle pattern from preadsorbed particle layers. Microparticle desorption was regulated by dielectrophoretic attracting forces generated by individual pixel electrodes, tangential detaching forces of an air flow, and adhesion forces on the microchip surface. A theoretical consideration of the acting forces showed that without pixel voltage, the tangential force applied for particle detachment exceeded the particle adhesion force. When the pixel voltage was switched on, however, the sum of attracting forces was larger than the tangential detaching force, which was crucial for desorption efficiency. In our experiments, appropriately large dielectrophoretic forces were achieved by applying high voltages of up to 100 V on the pixel electrodes. In addition, electrode geometries on the chip's surface as well as particle size influenced the desorption quality. We further demonstrated the compatibility of this procedure to complementary metal oxide semiconductor chip technology, which should allow for an easy technical implementation with respect to high-resolution microparticle deposition. 相似文献
6.
Differential optical absorption spectroscopy (DOAS) of atmospheric trace gases requires the detection of optical densities below 0.1%. Photodiode arrays are used more and more as detectors for DOAS because they allow one to record larger spectral intervals simultaneously. This type of optical multichannel analyzer (OMA), however, shows sensitivity differences among the individual photodiodes (pixels), which are of the order of 1%. To correct for this a sensitivity reference spectrum is usually recorded separately from the trace-gas measurements. Because of atmospheric turbulence the illumination of the detector while an atmospheric absorption spectrum is being recorded is different from the conditions during the reference measurement. As a result the sensitivity patterns do not exactly match, and the corrected spectra still show a residual structure that is due to the sensitivity difference. This effect usually limits the detection of optical densities to approximately 3 × 10(-4). A new method for the removal of the sensitivity pattern is presented in this paper: Scanning the spectrometer by small wavelength increments after each readout of the OMA allows one to separate the OMA-fixed pattern and the wavelength-fixed structures (absorption lines). The properties of the new method and its applicability are demonstrated with simulated spectra. Finally, first atmospheric measurements with a laser long-path instrument demonstrate a detection limit of 3 × 10(-5) of a DOAS experiment. 相似文献
7.
Andreas Förner Jan Vollhüter Anna Krapf Abdullah Jamjoom Daniel Hausmann Benjamin Wahlmann Zongwen Fu Carolin Körner Steffen Neumeier Mathias Göken 《Advanced Engineering Materials》2023,25(15):2300407
By increasing the density of interfaces in NiAl–CrMo in situ composites, the mechanical properties can be significantly improved compared to conventionally cast material. The refined microstructure is achieved by manufacturing through electron beam powder bed fusion (PBF-EB). By varying the process parameters, an equiaxed or columnar cell morphology can be obtained, exhibiting a plate-like or an interconnected network of the (Cr,Mo) reinforcement phase which is embedded in a NiAl matrix. The microstructure of the different cell morphologies is investigated in detail using scanning electron microscope, transmission electron microscopy, and atom probe tomography. For both morphologies, the mechanical properties at elevated temperatures are analyzed by compression and creep experiments parallel and perpendicular to the building direction. In comparison to cast NiAl and NiAl–(Cr, Mo), the yield strength of the PBF-EB fabricated specimens is significantly improved at temperatures up to 1,027 °C. While the columnar morphology exhibits the best improved mechanical properties at high temperatures, the equiaxial morphology shows nearly ideal isotropic mechanical behavior, which is a substantial advantage over directionally solidified material. 相似文献
8.
U. P. Hausmann Philipp Joerges J. Heinzl F. E. Talke 《Microsystem Technologies》2009,15(10-11):1747-1751
To increase the storage density of hard disk drives, the flying height of the slider needs to be reduced to <10 nm. This requires super-smooth surfaces of the disk and slider. As the roughness decreases, stiction and adhesion are found to increase substantially leading to failures of the head/disk interface. Texturing the slider surface is a well-known approach to this issue. In this study we investigated laser ablation as a potential process for texturing magnetic recording sliders. It was found that straight laser machining caused unwanted re-deposition of material. These deposits could be significantly reduced by using a chemical etching enhanced laser process. 相似文献
9.
Braun-Falco together with Marghescu described 1965 for the first time the clinical picture of bullous congenital poikilodermia. In reviewing 15 cases of the literature and one own case this disease is discussed here as an own nosological entity within the congenital poikilodermias and it is suggested to use the designation "Braun-Falco-Marghescu-Syndrome" according to the first describers. 相似文献
10.
Lars Wittmaack Bernhard Esslinger Ludger Schmidt Benjamin Strenge Arno Wacker 《Datenschutz und Datensicherheit - DuD》2016,40(5):271-277
Der ?elektronische Brief“ bzw. die elektronische Mail (E-Mail) ist seit über 30 Jahren im privaten wie beruflichen Umfeld im Einsatz. Behörden, Steuerbüros, Krankenhäuser, Finanzinstitute und viele weitere Gruppen versenden und empfangen E-Mails, um Informationen auszutauschen. Innerhalb kurzer Zeit findet eine E-Mail ihren Weg vom Sender in Deutschland zum Empfänger in beispielsweise den USA. Wie funktioniert das? Und was hat es mit E-Mail-Verschlüsselung auf sich? Dieser Artikel betrachtet die grundlegende technische Funktionsweise der E-Mail sowie Hintergründe und Funktionsweise der Verschlüsselung mit S/MIME und PGP. 相似文献