Study of a BGO calorimeter using electron and hadron beams from 1 to 50 GeV

A calorimeter of 25 bismuth germanate (BGO) crystals equipped with silicon photodiode readout has been tested at the CERN SPS in the energy range 1–50 GeV. The response for electrons has been shown to be linear in this energy range and the rms resolution obtained ( ) is approximately 1%, for E > 4 GeV. The electron/pion separation was found to be better than 1:500 in the energy range 1–20 GeV. Data on lateral and longitudinal shower development were compared with the results of a Monte Carlo simulation using the SLAC-EGS program and found to be in good agreement.     

Development of calibration models for quality control in the production of ethylene/propylene copolymers by FTIR spectroscopy,multivariate statistical tools,and artificial neural networks

Principal component regression (PCR), partial least squares (PLS), StepWise ordinary least squares regression (OLS), and back‐propagation artificial neural network (BP‐ANN) are applied here for the determination of the propylene concentration of a set of 83 production samples of ethylene–propylene copolymers from their infrared spectra. The set of available samples was split into (a) a training set, for models calculation; (b) a test set, for selecting the correct number of latent variables in PCR and PLS and the end point of the training phase of BP‐ANN; (c) a production set, for evaluating the predictive ability of the models. The predictive ability of the models is thus evaluated by genuine predictions. The model obtained by StepWise OLS turned out to be the best one, both in fitting and prediction. The study of the breakdown number of samples to be included in the training set showed that at least 52 experiments are necessary to build a reliable and predictive calibration model. It can be concluded that FTIR spectroscopy and OLS can be properly employed for monitoring the synthesis or the final product of ethylene–propylene copolymers, by predicting the concentration of propylene directly along the process line. © 2008 Wiley Periodicals, Inc. J Appl Polym Sci, 2008     

Radical abdominopelvic lymphadenectomy: historic perspective and current role in the surgical management of rectal cancer

Radical abdominopelvic lymphadenectomy for rectal cancer is based on the tenet that removal of all potentially involved lymphatic tissue will yield a lower rate of locoregional failure and improve survival. At centers with extensive experience with the procedure, the operating time is only modestly prolonged compared with conventional resection. Blood loss and postoperative hospitalization are not significantly increased. Urinary dysfunction and impotence associated with radical abdominopelvic lymphadenectomy (as high as 80 percent and 76 percent, respectively, in recent series) have been major deterrents to its more routine application. Preservation of the hypogastric plexus and even selective preservation of a unilateral S4 nerve root have been shown to reduce the occurrence of genitourinary complications. Improved five-year survival of 68 percent and local recurrence rates of 5 to 20 percent for TNM Stage III cancers have been achieved with radical abdominopelvic lymphadenectomy. These results compare favorably with recent trials of adjuvant chemoradiation after conventional resection in stage-matched patients. The rationale, evolution, and application of radical abdominopelvic lymphadenectomy to the surgical management of rectal cancer are critically examined. The potential benefits of radical abdominopelvic lymphadenectomy, which have been demonstrated in nonrandomized trials, should be evaluated in a prospective and properly randomized study to clearly establish or refute its efficacy.     

Dental caries in nineteenth century upper Canada

This study examines the presence of dental caries in a large sample of adult skeletons from the 19th century cemetery of St. Thomas' Anglican Church in Belleville, Ontario. The cemetery was used from 1821 to 1874. Caries prevalence and frequencies of diseased and missing teeth were calculated both by observing summary statistics of individual rates and by the total sample of teeth. Postmortem tooth loss is low in this sample and antemortem tooth loss is highest in first mandibular molars, all other molars and then premolars. Age at death, but not sex, was found to be significantly related to the overall Caries Rate while both age and sex were significantly associated with the Diseased-Missing Index. The increase in diseased and missing teeth in older individuals is expected while the sex difference is not explained by simple dietary factors. When compared to reports on British and American samples, caries and antemortem tooth loss in the St. Thomas' sample is most similar to a pre-1850 British group and higher than American samples. Although there is undoubtedly a complex of factors contributing to caries prevalence in this sample, more data are required from large historic samples, particularly from the American northeast and late 19th century Britain, to have a clearer understanding of the influence of diet, cultural, and environmental factors affecting caries rates in historic populations.     

Frequency dependence of the spin-fluctuation spectrum in Pd: Calculations within the finite bandwidth model

The frequency dependence of the electron-paramagnon spectrumP() in Pd is calculated within the finite bandwidth model. It is found that for an almost full band, the magnitude, the range, and the position of the peak frequency inP() are dramatically reduced compared to their values in the usual paramagnon theory. Also, we find that the frequency dependence of the spin-fluctuation contribution to the electron self-energy is strongly affected by a close proximity of the Fermi level to the top of the band. We speculate that an unusually large value of the Coulomb pseudopotential is probably partially responsible for the absence of superconductivity in Pd.     

On the evolution of homogeneous two-robot teams: clonal versus aclonal approaches

This study compares two different evolutionary approaches (clonal and aclonal) to the design of homogeneous two-robot teams (i.e. teams of morphologically identical agents with identical controllers) in a task that requires the agents to specialise to different roles. The two approaches differ mainly in the way teams are formed during evolution. In the clonal approach, a team is formed from a single genotype within one population of genotypes. In the aclonal approach, a team is formed from multiple genotypes within one population of genotypes. In both cases, the goal is the synthesis of individual generalist controllers capable of integrating role execution and role allocation mechanisms for a team of homogeneous robots. Our results diverge from those illustrated in a similar comparative study, which supports the superiority of the aclonal versus the clonal approach. We question this result and its theoretical underpinning, and we bring new empirical evidence showing that the clonal outperforms the aclonal approach in generating homogeneous teams required to dynamically specialise for the benefit of the team. The results of our study suggest that task-specific elements influence the evolutionary dynamics more than the genetic relatedness of the team members. We conclude that the appropriateness of the clonal approach for role allocation scenarios is mainly determined by the specificity of the collective task, including the evaluation function, rather than by the way in which the solutions are evaluated during evolution.     

Computational study on the interaction of a ring-hydroxylating dioxygenase from Sphingomonas CHY-1 with PAHs

The massive computational resources available in the framework of a grid paradigm approach represent an emerging tool in the bioinformatics field. In this paper, we used the above approach in the rapid determination of the interactions between the ring-hydroxylating dioxygenase, comprised six enzymatic subunits, and polycyclic aromatic hydrocarbons (PAHs) in their optimal positions. The results were obtained by simulating enzyme dynamics at 300 K through molecular dynamics calculations. For the first time, the equilibrated structure of the dioxygenase revealed a network of channels throughout the enzyme that were sufficiently large to allow a flow of small ions or molecules from the inner core of the complex to its exterior surface. The ring-hydroxylating dioxygenase was able to interact with some of the studied PAHs. Additionally, not only the number of aromatic rings but also the PAH shape were critical in predicting the ability of the dioxygenase to interact with these types of molecules. Docking calculations shed light on a new possible binding site that is far from the enzymatic one, which is potentially interesting in considering the stability of the enzyme itself.     

Two Enhanced Fourth Order Diffusion Models for Image Denoising

This paper presents two new higher order diffusion models for removing noise from images. The models employ fractional derivatives and are modifications of an existing fourth order partial differential equation (PDE) model which was developed by You and Kaveh as a generalization of the well-known second order Perona-Malik equation. The modifications serve to cure the ill-posedness of the You-Kaveh model without sacrificing performance. Also proposed in this paper is a simple smoothing technique which can be used in numerical experiments to improve denoising and reduce processing time. Numerical experiments are shown for comparison.