Non-Gaussian Model for Ringing Phenomena in Offshore Structures

Significant interest has been shown in identifying the nonlinear mechanisms that induce a ringing type response in offshore structural systems. This high frequency transient type response has been observed in offshore systems, particularly in tension leg platforms (TLPs). Given the implications of this behavior on the fatigue life of TLP tendons, it is essential that ringing be considered in the overall response evaluation. This study presents two non-Gaussian probabilistic models of nonlinear viscous hydrodynamic wave forces that induce ringing. The response of a single-degree-of-freedom system exposed to these non-Gaussian wave force models is then evaluated using analytical and numerical studies based on the It? differentiation rule and the Monte Carlo simulation procedure, respectively. The results demonstrate that the proposed models induce ringing type response in a simplified structure. This study provides a probabilistic framework for modeling ringing type phenomenon which will serve as a building block for more refined hydrodynamic load models.     

Synthesis and Anti-Cancer Activity of New Pyrazolinyl-Indole Derivatives: Pharmacophoric Interactions and Docking Studies for Identifying New EGFR Inhibitors

Newly designed series of indole-containing pyrazole analogs, pyrazolinylindoles, were synthesized, and their structures were confirmed based on the spectral data of the ¹H NMR, ¹³C NMR, and HR-MS analyses. Preliminary anti-cancer activity testings were carried out by the National Cancer Institute, United States of America (NCI, USA). Compounds HD02, HD05, and HD12 demonstrated remarkable cytotoxic activities against nine categories of cancer types based cell line panels which included leukemia, colon, breast, melanoma, lungs, renal, prostate, CNS, and ovarian cancer cell lines. The highest cytotoxic effects were exhibited by the compounds HD02 [1-(5-(1-H-indol-3-yl)-3-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)-2-phenylethanone], HD05 [1-(3-(4-chlorophenyl)-5-(1H-indol-3-yl)-4,5-dihydro-1H-pyrazol-1-yl)-2-phenoxyethanone], and HD12 [(3-(4-chlorophenyl)-5-(1H-indol-3-yl)-4,5-dihydro-1H-pyrazol-1-yl)(pyridin-4-yl)methanone] against some of the 56 types of NCI-based cell lines in different panels. Compound HD05 showed the maximum range of cancer cell growth inhibitions against all categories of the cell lines in all nine panels. On average, in comparison to the referral standard, imatinib, at a dose level of 10 µM, the HD05 showed significant activity against leukemia in the range of 78.76%, as compared to the imatinib at 9% of cancer cells’ growth inhibitions. Molecular docking simulation studies were performed in silico on the epidermal growth factor receptor (EGFR) tyrosine kinase, in order to validate the activity.     

An effective back‐off selection technique for reliable beacon reception in VANETs

In safety‐critical scenarios, reliable reception of beacons transmitted by a subject vehicle is critical to avoid vehicle collision. According to the employed contention window sizes in IEEE 802.11p, beacons are transmitted with a small contention window size. As a result, multiple vehicles contend for the shared channel access by selecting the same back‐off slot. This is a perfect recipe for synchronous collisions wherein reliable beacon delivery cannot be guaranteed for any vehicle. We consider the problem of selecting the back‐off slots from the current contention window to provide reliable delivery of beacons transmitted by a subject vehicle to its neighbors. Given a safety scenario, we propose a Pseudo‐Random Number Generator (PRNG)‐inspired back‐off selection (PBS) technique. The proposed technique works on the hypothesis that synchronous collisions of beacons transmitted by a subject vehicle can be reduced if all its neighbors select different back‐off slots (ie, not the back‐off slot selected by the subject vehicle). The discrete‐event simulations demonstrate that PBS can increase the overall message reception from a subject vehicle, in comparison with the uniform random probability back‐off selection in IEEE 802.11p.     

A new design approach for dual‐band patch antenna serving Ku/K band satellite communications

A printed planar antenna with simple and intelligent geometrical structure has been proposed for Ku/K band satellite communication systems. The radiating patch of the antenna is formed by cutting rectangular slots and extending the radiating element to some extent. The final design of the antenna with optimized parameters is fabricated on ceramic–polytetrafluoroethylene substrate materials of dielectric constant ε_r = 10.2. The antenna is excited through a microstrip feed line and has reduced ground plane that covers only the non‐radiating portion of the antenna. The reduced complexity of the antenna is easy to fabricate and has overall dimension of 40 × 35 × 1.905 mm³. The results from experimental analysis show that the proposed antenna can guarantee a wide bandwidth of 12.0 to 16.4 GHz at lower band, and the upper band covers the frequency in the range of 17.53 to 19.5 GHz. The antenna has achieved appreciable gain in the range of 3.14 to 4.68 dBi for lower band and 2.03 to 3.65 dBi for upper band. The proposed antenna has offered almost symmetrical and directional radiation pattern that is essentially suitable for serving Ku/K band satellite applications. Copyright © 2015 John Wiley & Sons, Ltd.     

Effect of key process variables on mechanical properties of blended vortex spun yarns

A study of significant factors and their interaction during vortex yarn spinning has been carried out to achieve desired mechanical properties of the polyethylene terephthalate/cotton blended yarns which can offer process and performance advantages. The key significant factors, i.e. feed ratio, air pressure and spindle size were varied in a mixed-level factorial design. The mechanical properties (count lea strength product, tenacity and elongation at break) were studied and feed ratio was found to significantly affect the tenacity and elongation at break of spun yarns. A significant effect of these parameters was observed on the diameter and hairiness of the Muratec vortex spun yarn.     

Parallel query execution over encrypted data in database-as-a-service (DaaS)

The Journal of Supercomputing - The main challenge in database-as-a-service is the security and privacy of data because service providers are not usually considered as trustworthy. So, the data...     

Silicon Seed Priming Combined with Foliar Spray of Sulfur Regulates Photosynthetic and Antioxidant Systems to Confer Drought Tolerance in Maize (Zea mays L.)

Silicon - The present study evaluated the effect of silicon (Si) seed priming and sulfur (S) foliar spray on drought tolerance of two contrasting maize hybrids viz. drought tolerant Hi-Corn 11 and...     

Influence of Different Additives on the Interaction of Quinolone Antibiotic Drug with Surfactant: Conductivity and Cloud Point Measurement Study

Conductometric and cloud point (CP) measurement studies have been performed to investigate the interaction of tetradecyltrimethylammonium bromide (TTAB) and Triton® X-100 (TX-100) with ciprofloxacin hydrochloride (CFH) in different solvents over the temperature range of 295.15–315.15 K. CFH is used for the treatment of various bacterial infections. The observed critical micelle concentration (CMC) values of TTAB were found to be reduced in the presence of electrolytes (Na₂SO₄/Na₃PO₄), and this reduction proceeds with the elevation of salt concentration. The order of the CMC of TTAB follows the trend: > >. The observed CMC values of TTAB were found to increase with increasing temperature and decrease with increasing concentration of CFH in aqueous medium. The values of Gibbs free energy of micellization () for the TTAB/TTAB + CFH mixture were found to be negative, implying spontaneous micellization. The estimated CP of TX-100 decreases with increasing concentration of TX-100 in aqueous medium. The CP values first decrease with increasing concentration of CFH and then increase at higher concentration of CFH almost in all cases investigated. The values of free energy of clouding were found to be positive in all cases studied implying that phase separation of TX-100 was nonspontaneous. The other thermodynamic parameters associated with the micellization of TTAB and the phase separation of TX-100 were estimated and explained.