Khartoum

Khartoum is the capital of a country whose creation resulted more from colonial politicians' desires for straight boundaries than from local social or political realities. This profile traces Khartoum's history of growth and planning legislation since its establishment as an administrative capital at the turn of the century. The city, developed from three separate towns, grew rapidly after independence as administrative functions grew and industrial development started. However, lack of an effective mechanism for planning and control of the city's growth has meant that a pattern of sprawling low-density land uses has developed, with inadequate services and deteriorating environmental standards. What planning control does exist operates through land-use zoning and building byelaws, though often arbitrarily applied. Planning problems are exacerbated by high population growth rates and national economic problems.     

A Specific Stability Indicating Hplc Method to Determine Diclofenac Sodium in Raw Materials and Pharmaceutical Solid Dosage Forms

A high performance liquid chromatography method is described for the determination of diclofenac sodium, its related compounds and degradation products in commercial sources of raw materials and solid dosage forms. This method is specific, accurate and stability indicating. The method employs a reverse-phase octylsilane (C18) column with a mobile phase composed of acetonitrile/methanol/pic B-6 (25:25:50) and detection at 229 nm. The method resolves six principal related compounds with quantitation in the range 0.3-1.5%. Assay recoveries by spiking commercial formulations with diclofenac sodium were 99.64 ± 1.30%. Drug content in several commercial formulations are reported. Accelerated stability tests were conducted on raw materials and drug products and 1-(2,6-dichlorophenyl)-2-indolin-2-one was identified for the first time as a degradation product in solid dosage forms which are stressed under humidity and heat.     

Sidechain liquid crystal polymers

Research has continued in the field sidechain liquid crystal polymers over recent years, but it is becoming clearer that this research is being directed away from the traditional technology areas of electro-optic devices and researchers are developing new and exciting applications for this novel state of matter.     

N.m.r. studies on the effect of water on the glass transition of polystyrene

These investigations are concerned with water-polymer interactions in polymer latices. It is known that water can act as a plasticizer for many solid polymers and cause a reduction in the glass transition temperature, T_g, of the amorphous regions. Experiments were carried out to determine whether pulsed n.m.r. techniques could be used to study the T_g of a polymer suspension and hence the influence of water and electrolyte on it. From T₁ and T₂ proton relaxation measurements as a function of temperature on polystyrene latex systems it was shown that the presence of water lowers the T_g of the polymer particles (by about 10°C), the effect being slightly greater in the presence of concentrated electrolyte. The extent of electrolyte penetration into the particles was deduced by studying relaxation as a function of particle diameter in latices containing paramagnetic Mn²⁺ ions. Using simple theories of relaxation and spin diffusion it was concluded that for all but the smallest particles electrolyte penetration is restricted to a very thin shell of the order of 1 nm. These conclusions were supported by the results of similar measurements on PTFE particles.     

Selective toxicity of hydroxyl-rich carbon nanodots for cancer research

Nano Research - The toxicity of nanoparticles in a biological system is an integration of effects arising from surface functionality, particle size, ionic dissolution, etc. This complexity suggests...     

Robust finite-time boundedness of multi-agent systems subject to parametric uncertainties and disturbances

In this paper, we consider finite-time control problems for linear multi-agent systems subject to exogenous constant disturbances and impulses. Some sufficient conditions are obtained to ensure the finite-time boundedness of the multi-agent systems, which could be then reduced to a feasibility problem involving linear matrix inequalities. Numerical examples are given to illustrate the results.     

Towards the next generation of artificial neural networks for civil engineering

The purpose of this paper is to stimulate interest within the civil engineering research community for developing the next generation of applied artificial neural networks. In particular, it identifies what the next generation of these devices needs to achieve, and provides direction in terms of how their development may proceed. An analysis of the current situation indicates that progress in the development of artificial neural network applications has largely stagnated. Suggestions are made for advancing the field to the next level of sophistication and application, using genetic algorithms and related techniques. It is shown that this approach will require the design of some very sophisticated genetic coding mechanisms in order to develop the required higher-order network structures, and will utilize development mechanisms observed in nature such as growth, self-organization, and multi-stage objective functions. The capabilities of such an approach and the way in which they can be achieved are explored with reference to the problems of: (a) determining truck attributes from the strain envelopes they induce in structural members when crossing a bridge, and; (b) developing a decision support system for dynamic control of industrialized manufacturing of houses.