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1.
M Huttova I Hartmanova K Kralinsky J Filka J Uher J Kurak S Krizan V Krcmery 《Canadian Metallurgical Quarterly》1998,17(11):1012-1015
PURPOSE OF THE STUDY: To assess efficacy and safety of fluconazole in neonates with Candida fungemia. STUDY DESIGN: Multicenter prospective protocol of all fungemias appearing between January 1, 1993, and December 31, 1997, in four major university hospitals. RESULTS: Forty neonates, 28 of them with very low birth weight (<1500 g; 30.5 median gestation week), with documented Candida albicans fungemia were treated with intravenous fluconazole in a daily dosage of 6 mg/kg once daily for 6 to 48 days. Thirty-four received fluconazole as monotherapy and 6 received it in combination with amphotericin B. Thirty-two (80%) were cured; 4 of them relapsed despite at least 14 days of therapy, but they were ultimately cured without sequelae. Eight other neonates died, 4 because of fungal infection and 4 because of prematurity or hemorrhage or lung failure, with fungemia (20% overall and 10% attributable mortality). Two neonates had elevated liver enzymes during fluconazole therapy and 2 others had elevated serum creatinine during fluconazole monotherapy. In none of them did these abnormalities necessitate discontinuation of antifungal therapy. In 8 neonates fungal meningitis developed as a complication of fungemia. All but 3 fungemias were C. albicans; 3 were Candida parapsilosis. CONCLUSIONS: Fluconazole was safe and effective antifungal therapy even in complicated or Candida fungemia in neonates and in infants with very low birth weight. 相似文献
2.
Thomas E. Uher 《Construction Management & Economics》2013,31(6):495-508
The use of non-standard, contractor-prepared subcontract conditions is widespread in the Australian construction industry. Many conditions in such subcontracts are harsh and are viewed by Australian subcontractors as the most critical risk for which they make risk allowances in the bid price. 相似文献
3.
Uher Richard A. Sathi Neena Sathi Arvind 《Industry Applications, IEEE Transactions on》1984,(3):472-483
An energy cost reduction study was conducted on the Washington Metropolitan Area Transit Authority Metrorail system. Its primary objectives were to classify primary energy end uses and identify conservation methods which have the highest potential for reducing the electric bill. The effort involved analyzing present energy costs, developing cost- effective conservation strategies, determining the savings associated with the strategies by simulation, recommending appropriate strategies for implementation and outlining a program for executing the recommendations. Although the effort involved both traction and support energy, only the traction energy aspects of the study are reported. It is the first time that the energy management model developed for the transit industry by the Rail Systems Center at Carnegie-Mellon University was comprehensively applied to a rapid transit property. The application was verified by comparing the simulated results to actual data. For anl practical purposes, the simulated results agree to within three percent of the actual energy consumption. Four traction energy conservation strategies were recommended for implementation based on high benefit and low cost. These are coasting, passenger load factor improvement, planned catch-up operation, and regeneration of braking energy. All of these strategies have payback periods of less than three years. 相似文献
4.
Bernsteen Stanley A. Uher Richard A. Romualdi James P. 《Industry Applications, IEEE Transactions on》1983,(5):802-817
Past efforts in railway improvement have focused on increased train stability and ride quality for safe and smooth operations at higher speed. The question of energy consumption has rarely been considered. In view of projections of higher fuel costs and increased rail traffic volume, energy effects caused by improved train resistance should be considered. First-order expressions for the rolling resistance of freight trains on level tangent track were derived from the basic principles of physics and engineering. The average power dissipated by the suspension system was obtained from a linear model of the track train system. Hysteresis in the soil is computed using basic principles of soil mechanics. Losses due to wheel rolling friction, imposed wheel sliding, and bearings were estimated from simple engineering and considerations. Rolling resistance as would be measured in coast down or drawbar pull tests on level tangent track is found to depend strongly on the quality of the track as well as weight and speed. On good track, most of the rolling resistance is due to bearing resistance, while on poor track, suspension losses predominate. Empirical expressions such as the Davis formula, which have been used in the past by the railroad industry, are unable to describe train rolling resistance adequately because of the way in which they are parameterized. Some of the parameter values obtained from fits to experimental data do not carry the physical meaning with which they were traditionally associated. 相似文献
5.
Nonstoichiometry of tetradymite-type crystals A2VB3VI that are grown from stoichiometric melts leads to the formation of native defects in the crystal lattice (predominantly antisite
defects, AB−1 and vacancies VB+2 in the anion sublattice). This paper summarizes the basic ideas concerning a point defect model in A2VB3VI crystals. It turns out that a variety of doping elements interact with the native defects. Such interactions alter the concentration
of free charge carriers, affect the doping efficiency, and modify the transport properties. Detailed understanding of the
defect structure in tetradymite-type crystals is very important as it impacts on the efficiency of these materials when used
as active elements in thermoelectric coolers. 相似文献
6.
Ba+Yb double-filled n-type skutterudites with a modest degree of charge compensation by Fe on the Co lattice have been synthesized and compacted
by spark-plasma sintering, and their thermoelectric properties evaluated at temperatures up to 800 K. Although this approach
to making n-type skutterudites seems counterintuitive, the presence of Fe leads to a reduction in the thermal conductivity while it
preserves a robust Seebeck coefficient. Consequently, a high ZT in excess of 1.3 was achieved at 800 K in these Fe-containing n-type skutterudite compounds. 相似文献
7.
A 180° nonreciprocal ferrite phase shifter with stepped dielectric impedance transformer sections at both ends is designed using the method of field expansion into eigenmodes. The rigorous optimisation method includes the higher-order mode interaction between the step discontinuities. The design achieves compact and simple components, as relatively thick, and consequently short, uniform ferrite slabs of standard dimensions may utilised. A computer-optimized design example provides about 180° ± 1° nonreciprocal differential phase shift between 12.2 and 12.8 GHz together with more than 24dB return loss. 相似文献
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