全文获取类型
收费全文 | 1942篇 |
免费 | 4篇 |
专业分类
电工技术 | 2篇 |
综合类 | 1篇 |
化学工业 | 16篇 |
金属工艺 | 1篇 |
机械仪表 | 3篇 |
建筑科学 | 1篇 |
轻工业 | 5篇 |
冶金工业 | 1916篇 |
自动化技术 | 1篇 |
出版年
2020年 | 2篇 |
2018年 | 3篇 |
2017年 | 1篇 |
2015年 | 1篇 |
2014年 | 1篇 |
2013年 | 2篇 |
2011年 | 1篇 |
2010年 | 1篇 |
2007年 | 1篇 |
2006年 | 2篇 |
2005年 | 1篇 |
2003年 | 5篇 |
2000年 | 2篇 |
1999年 | 53篇 |
1998年 | 561篇 |
1997年 | 315篇 |
1996年 | 220篇 |
1995年 | 137篇 |
1994年 | 116篇 |
1993年 | 99篇 |
1992年 | 9篇 |
1991年 | 23篇 |
1990年 | 30篇 |
1989年 | 24篇 |
1988年 | 30篇 |
1987年 | 22篇 |
1986年 | 23篇 |
1985年 | 22篇 |
1984年 | 1篇 |
1983年 | 3篇 |
1982年 | 4篇 |
1981年 | 7篇 |
1980年 | 14篇 |
1979年 | 1篇 |
1978年 | 9篇 |
1977年 | 66篇 |
1976年 | 129篇 |
1975年 | 4篇 |
1964年 | 1篇 |
排序方式: 共有1946条查询结果,搜索用时 15 毫秒
1.
2.
Twenty-six patients with an intracardiac myxoma underwent surgical resection at our institution from 1977 through 1992. Left atrial myxoma was diagnosed in 22 patients, left ventricular in 1, right atrial in 2, and right ventricular in 1. Six patients were asymptomatic; preoperative symptoms included dyspnea, arrhythmias, embolic episodes, and syncope. The diagnosis was established with transthoracic echocardiography in all cases but one. Surgery was performed in all cases with the aid of cardiopulmonary bypass with moderate hypothermia and cold crystalloid cardioplegia. One patient with a left ventricular myxoma died in a comatose state during the immediate postoperative period. Long-term clinical and echocardiographic evaluation was performed in 19 patients; results were excellent (all the patients were in New York Heart Association functional class I or II), and no recurrences were documented. The clinical characteristics, diagnostic methods, and surgical approach are presented and discussed. 相似文献
3.
4.
D Cullinan F Johnson AP Grollman M Eisenberg C de los Santos 《Canadian Metallurgical Quarterly》1997,36(39):11933-11943
Vinyl chloride reacts with cellular DNA producing 3,N4-etheno-2'-deoxycytidine (epsilonC) along with other exocyclic adducts. The solution structure of an oligodeoxynucleotide duplex containing an epsilonC.dG base pair was determined by high-resolution NMR spectroscopy and molecular dynamics simulations. NMR data indicated that the duplex adopts a right-handed helical structure having all residues in anti orientation around the glycosylic torsion angle. The epsilonC adduct has a sugar pucker in the C3'-endo/C4'-exo region while the rest of the residues are in the C2'-endo/C3'-exo range. NOE interactions established Watson-Crick alignments for canonical base pairs of the duplex. The imino proton of the lesion-containing base pair resonated as a sharp signal that was resistant to water exchange, suggesting hydrogen bonding. Restrained molecular dynamics simulations generated three-dimensional models in excellent agreement with the spectroscopic data. The refined structures are slightly bent at the lesion site without major perturbations of the sugar-phosphate backbone. The adduct is displaced and shifted toward the major groove of the helix while its partner on the complementary strand remains stacked. The epsilonC(anti).dG(anti) base pair alignment is sheared and stabilized by the formation of hydrogen bonds. The biological implications of structures of epsilonC-containing DNA duplexes are discussed. 相似文献
5.
IuP Spizhenko AV Biliaiev AM Zaremba IV Nahorny? AP Tkachenko 《Canadian Metallurgical Quarterly》1997,43(5-6):42-48
Investigated all links of oxygen homeostasis of patients in early period afterwards surgical stoppage gastro-intestinal bleeding and urgent intravascular volume replacement. Macrodelivery of oxygen (DO2) was reduced in two and more time in comparison with norm predominant in connection with anemia. In spite of the infringement of transport of oxygen through alveolar-capillary membrane (especially in patients with complications and death in early postoperative period), little affected of degree of hemoglobin saturation by oxygen. Despite decrease of erythrocyte zeta-potential, largely expressed in cases of lethal outcome, considerable infringement of passage through microcirculation vessels is fixed was not. The increase of degree of morbidity and anaerobic metabolism in early postoperative period was accompanied of hyperdynamic hemodynamic reaction. The increase of degree of morbidity was accompanied of increase oxygen deficit owing to infringement of oxidoreduction in fabries also. 相似文献
6.
SD Shiian SV Kha?dukov AL Pukhal''ski? AP Toptygina NV Bovin 《Canadian Metallurgical Quarterly》1996,41(2):24-29
The interaction of human peripheral blood leukocytes with alpha 1-acid glycoprotein (AGP), its glycoforms as well as neoglyco-conjugates representing carbohydrate chains of AGP or its fragments was studied by flow cytometry. It was shown that the main target cells for AGP as well as for conjugates of its carbohydrate chains with polyacrylamide (PAA) are monocytes and polymorphonuclear leukocytes but not lymphocytes. The interaction of AGP with monocytes and granulocytes are mediated by its carbohydrate chains: the binding of AGP with cells was inhibited by AGP, AGP oligosaccharides as well as conjugates of oligosaccharides and its fragments with PAA. The data obtained show the existence of monocyte (and granulocyte) receptors which interact with complex type sialooligosaccharides of AGP. 相似文献
7.
Experimental results are presented to show that the adhesion force is the single most important limiting factor in high-resolution atomic force microscopy of DNA in air, prepared by the cytochrome-C-assisted spreading method. It is also shown that humidity plays a minor role in the control of probe force. Using a pure carbon film as the substrate to clean the AFM tip prior to imaging, it is demonstrated that 4-6 nm resolution on DNA can be routinely obtained by the atomic force microscope with commercial Si3N4 pyramid cantilevers. We also show that in organic solvents a resolution of up to 3 nm can be obtained under optimal conditions. 相似文献
8.
9.
FV Elmslie AJ Vivian H Gardiner C Hall AP Mowat RM Winter 《Canadian Metallurgical Quarterly》1995,32(4):264-268
Alagille syndrome (AGS) is one of the major forms of chronic liver disease in childhood with severe morbidity and a mortality of 10 to 20%. It is characterised by cholestasis of variable severity with paucity of interlobular bile ducts and anomalies of the cardiovascular system, skeleton, eyes, and face. Previous studies suggest a wide variation in the expression of the disease and a high incidence of new mutations. To determine more accurately the rate of new mutations and to develop criteria for detecting the disorder in parents we systematically investigated parents in 14 families with an affected child. Clinical examination was supplemented by liver function tests, echocardiography, radiographic examination of the spine and forearm, ophthalmological assessment, and chromosome analysis. Six parents had typical anomalies in two or more systems pointing to the presence of autosomal dominant inheritance. Systematic screening of parents for the features defined in this study should improve the accuracy of genetic counselling. 相似文献
10.