分享阳光--比尔的公寓楼

这幢位于瑞士比尔郊区的公寓高三层,由8套大小不同的住宅单元所构成,所处位置能够俯瞰整个小镇,具有极佳的视野。下面的部分是跃层式的二层公寓,上面一层则是普通公寓。楼顶为公共活动区域,设有孩子们的游戏室,其屋顶形式与相邻的建筑风格颇为近似。基地东南向的陡坡非常理想地     

The band areas of proteins determined by fluorescent scanning in the commercial automated gel electrophoresis apparatus

An automated gel electrophoresis apparatus, recently available commercially, allows one to follow the band during electrophoresis in real time, and lends itself therefore to an evaluation of bandwidth as a function of migration time (the dispersion coefficient), resolution and band shape. These determinations assume the constancy of band area with migration time and at various gel concentrations. The purpose of the present study was to verify these assumptions. Representative proteins and sodium dodecyl sulfate (SDS)-proteins, either natively fluorescent or fluorescein carboxylate labeled, were found to exhibit band areas which approach constancy as a function of migration time in both agarose and polyacrylamide gel electrophoresis, provided that (i) the protein concentration under the band was low enough to obviate self-quenching of fluorescence; (ii) the separation of the protein of interest from contaminants had progressed sufficiently during the time at which band areas were measured; (iii) the baseline under the peak was sufficiently well defined. However, band areas decrease with increasing gel concentration. Protein peaks exhibited leading and trailing tails. The ratio of the combined tail area to total area appeared to be near-constant at varying migration times. However, that ratio increases with increasing gel concentration. The tail area does not appear to be an artifact of fluorometric detection since it is reproduced upon fluorimetric analysis of the protein eluted from gel slices after electrophoresis. However, it may be due to photochemical destruction under the conditions of repetitive fluorometric peak detection.     

Physiological actions of the neuropeptide Antho-RNamide on antagonistic muscle systems in sea anemones

Several studies have reported that the bulk aluminum (Al) concentration is increased in the brain in Alzheimer disease (AD), while other studies have failed to demonstrate an increase. Most of these investigations have had one or more methodological deficiencies, including lack of adequate neuropathological assessment; failure to age-match the control samples; small sample sizes, lacking statistical power; and geographical heterogeneity in the AD and control populations. The present population-based study of 92 clinically and histopathologically diagnosed AD patients and normal elderly nursing home residents was designed to avoid these potential biases. When a subsample of AD cases with the most severe brain pathology was compared with controls having no or minimal pathology, no statistically significant differences were found in the bulk aluminum concentration measured by graphite furnace atomic absorption spectrometry in frontal cortex (1.8 +/- 0.7 vs. 1.7 +/- 0.7 micrograms/g dry wt), temporal cortex (1.4 +/- 0.3 vs. 1.5 +/- 0.5 micrograms/g dry wt), liver (2.0 +/- 1.3 vs. 2.0 +/- 1.2 micrograms/g dry wt), or head of femur (2.4 +/- 1.6 vs. 2.2 +/- 1.0 micrograms/g ash wt). Within the whole series of 92 cases, there was no difference in the bulk aluminum concentration of the frontal cortex between individuals diagnosed as definite, probable, and possible cases of AD using the CERAD (Consortium to Establish a Registry for Alzheimer's Disease) criteria. The density of senile plaques and neurofibrillary tangles in frontal and temporal cortex showed no correlation with the bulk aluminum concentration. Logistic regression analyses, which controlled for age and sex, did not influence outcome for any of the comparisons. The data show conclusively that in AD, bulk aluminum concentration is not increased in two cortical brain regions that are selectively vulnerable to the neuropathological changes associated with this disorder.     

Recovery of SDS-protein and DNA using commercial automated gel electrophoresis apparatus

Forty-seven children afflicted with acute leukemia were studied at the Tata Memorial Hospital Bombay to record the occurrence of oral manifestations prior to and during chemotherapy. Lymphadenopathy was the most frequent single finding suggestive of leukemia during head and neck examination. Gingival abnormalities, bleeding gums and oral mucosal pallor were the other findings on initial oral examination. Due to immunosuppression caused by the chemotherapy drugs oral mucosal ulcerations, uncontrolled herpes, candidiasis and pseudomoniasis were observed.     

The results of complex social and ecologic study in the city of Ufa

The authors present results of social and ecologic study carried out in Ufa. The results describe the course of ecologically important processes and phenomena in correlation with the public subjective understanding. Public health is influenced by hygienic parameters of food and water quality as well as a complex of social, economic and psychologic factors. Weak correlation between those parameters and ambient air pollution necessitates more accurate approach to ecologic mapping of cities and to manipulation with data on lower atmosphere pollution with chemical hazards.     

Long-term prognosis for women with chronic pelvic pain without laparoscopically demonstrable cause

With the object of assessing the long-term prognosis and the frequencies of recurrence and remission in women chronic low abdominal pain without laparoscopically visible cause, questionnaire were sent in 1985 and 1991 to 55 women who had been submitted to laparoscopy in 1982-1984 for this reason. These women had been told that there was no demonstrable explanation of the pain experienced and were then discharged. 65% and 55% respectively had experienced and unfavourable course with considerable and continued symptoms. Only 22% stated in both investigations that they had experienced a favourable course and that they were, by and large, free from pain. 36% changed from an unfavourable to a favourable course or the reverse. The assessment made by the women was confirmed by a series of subordinate questions and this demonstrated a marked difference between the favourable and unfavourable courses of the condition. It is concluded that laparoscopy with exclusion of significant pathology is not, in itself, satisfactory as treatment of this patient group and that no improvement occurs in the course of time. The condition varies greatly with many recurrences and remissions and, for this reason, uncontrolled reports of the therapeutic effects are of no significance. When compared with the literature, it is suggested that this patient group should be referred early in the course of the condition to a therapist with specialist psychological/sexological insight and/or to a physiotherapist with interest in this patient group.     

The absorption of deuterium by carbon-based facing materials on components in contact with the plasma in a thermonuclear reactor

Conclusions The conditions have been proposed for performing modeling experiments making it possible to predict the accumulation of hydrogen isotopes in carbon materials which are in contact with a tokamak plasma acting as a source of particles having a flux density of between 3×10¹⁶ and 3×10¹⁹ cm⁻²·sec⁻¹. By analyzing the reemission fluxes formed in the stopping zone of the particles implanted from the plasma it is suggested that the action of the plasma as regards the sorption of hydrogen is identical to that of annealing the material in an atmosphere of hydrogen isotopes at a pressure of 1–10³ Pa and a temperature of 1200–1700 K. The quantity of absorbed deuterium in POCO, UAM, RGT-B, and USB increases as the temperature is lowered and the pressure is raised (1500 K, 0.66 Pa→1200 K, 133 Pa). As regards their sorption of deuterium, POCO, UAM, and RGT behave similarly. There is a tendency for the sorption capacity of materials doped with boron to be reduced. In a class of itself is the isotropic material USB, whose sorption capacity is a factor of 10–100 lower than that of undoped graphite. The introduction into these materials of radiation-induced defects (T=300 K) by means of ion irradiation in the range 0.1–1 dpa results in a continuous rise in the deuterium sorption capacity by a factor of 10–100 (up to 10⁻² atomic fraction). The USB graphite demonstrates record low increments in the sorption capacity. In the fluence range identical to 1–10 dpa the sorption capacity of carbon materials for hydrogen is almost constant. The process of the sorption of hydrogen isotopes can be described as the filling of two ensembles of traps, deep traps which are difficult to access and readily accessible Langmuir traps. In the RGT-B materials containing 0.1% of boron, the traps introduced by irradiation with 300-keV neon ions vanish on annealing in a vacuum (T=1800 K, t=1 min). Institute of Physical Chemistry, Russian Academy of Sciences. SINTEZ Scientific and Technical Center, Scientific-Research Institute of Electrophysical Apparatus. Graphite Scientific-Research Institute. National Scientific Center, Kharkov Physicotechnical Institute. Translated from Atomnaya énergiya, Vol. 82, No. 6, pp. 448–464, June, 1997.     

Pore force fields in carbon material and their interaction with gas molecules

It was shown that a pore in a solid has a force field that acts on molecules from the surrounding gas phase. The axial and radial distributions of forces were studied. The study showed that forces parallel to the pore axis operate at the entrance to and the exit from the pore. These forces can either impede or facilitate the entering of gas molecules into the inner space. Forces that have the radial direction act in the pore space and can either retain gas molecules on its central axis or increase the density of the gas in the space adjacent to pore walls. The influence of these forces alter the velocity distribution of gas filtration in the pore, thus leading to the situation that gas transport is realized along the walls under certain conditions. Equipotential field lines were obtained whose general view gives a clear illustration of the distribution of the field in the pore and in the adjacent environment.