A PC program for diagnosing abnormal growth, growth velocity and acceleration from longitudinal observations

A human fibroblastic cell line transformed by the SV40-T antigen sequence and continuously cultured for 7 months displayed large periodic variations in cell proliferation. This contrasted with other characteristics of this cell line that remained constant: mosaic cell shape, absence of cell contact inhibition, and predominance of a hypodiploid population. Similar fluctuations in proliferative capacity were also found during the long-term growth of a transformed but nonimmortalized human fibroblastic line prior to senescence, and in the established hamster fibroblastic Nil cell line. This growth pattern suggests a recurrent stimulation of growth in these three transformed cell lines. The proliferation pattern from cultured transformed cells may thus be complex and requires further investigation. These variations presumably influence major cell functions. This observation has important implications for the analysis of data from such cell lines.     

Relation Between Texture and Quality Characteristics of Rolled Stock and Control of Continuous Plastic Deformation

Metal Science and Heat Treatment - The relation between the texture parameters suggested earlier for controlling the properties under heat treatment and the quality characteristics of deformable...     

Thermal Expansion of BaO · 2B<Subscript>2</Subscript>O<Subscript>3</Subscript> in the Vitreous and Crystalline States: I. Thermal Expansion and Density of Barium Diborate Prepared from Monolithic Glass of the Same Composition

The thermal expansion and density of vitreous and polycrystalline barium diborates prepared by crystallization of monolithic glasses of stoichiometric composition are investigated in the temperature range 20–700°C. The glass crystallizes in the form of the α and β modifications depending on the heat treatment conditions. The α phase nucleates on the surface of the monolithic sample and grows inward the sample in the form of textured layers. The β phase nucleates in the melt bulk and grows in the form of spherulites. Textured polycrystalline barium diborate in the form of the α phase possesses a pronounced anisotropy of thermal expansion with respect to the direction of crystalline-layer growth. This is associated with the negative expansion along one of the crystallographic axes. The effective temperature coefficients of thermal expansion in the temperature range 20–600°C increase in the order: α phase-glass-β phase. Upon heating above 690°C, the β phase transforms partially into the α phase. This is accompanied by a considerable increase in the volume. The densities of the glass and polycrystalline samples in the temperature range 20–700°C increase in the order: glass-α phase–β phase.