The preferential mobilisation of C20 and C22 polyunsaturated fatty acids from the adipose tissue of the chick embryo: potential implications regarding the provision of essential fatty acids for neural development

The effects of 10 day clenbuterol administration on cardiac and skeletal muscle capillarities were studied, particularly in terms of the distribution of arteriolar and venular capillaries and their capillary density, in young (10-week-old) and middle-aged (37-week-old) male Wistar rats. Rats of the treated groups were fed a diet containing 2 mg kg-1 clenbuterol hydrochloride. In both young and middle aged rats, clenbuterol treatment increased the body wt and the weights of the heart and hindlimb muscles. The mean fibre cross-sectional area was significantly increased after the treatment in the left ventricle, soleus, plantaris and both deep and superficial portions of gastrocnemius (P < 0.01). In the left ventricle, the total capillary density and the density of venular capillaries were decreased after the treatment in both young (9 and 13%, respectively) and middle-aged rats (10 and 11%, respectively). A decrease in total capillary density was also observed in all skeletal muscles examined. In both young and middle-aged rats, the capillary-to-fibre (C:F) ratio and the proportion of each capillary did not change after the treatment in both the left ventricle and skeletal muscles. Clenbuterol significantly decreased the activity of succinate dehydrogenase in all skeletal muscles examined (P < 0.01). These results suggest that clenbuterol increased the diffusion distance for oxygen in the left ventricle and skeletal muscles. These changes may reduce the oxygen supply to tissues and increase muscle fatigability.     

Comparison of ribosomal DNA length and restriction site polymorphisms in Gremmeniella and Ascocalyx isolates

The small subunit (SSU) and the internal transcribed spacer (ITS) of nuclear ribosomal DNA genes from 27 specimens of the fungal genera Gremmeniella and Ascocalyx were amplified by PCR. Length polymorphisms were observed in the SSU and allowed the differentiation of four groups among the isolates tested: (i) Ascocalyx abietis; (ii) Gremmeniella isolates from Picea spp.; (iii) Gremmeniella isolates from Abies balsamea; and (iv) Gremmeniella isolates from Abies sacchalinensis, Larix spp., and Pinus spp. The amplified ITS was the same length for all Gremmeniella specimens and was 60 bp longer in A. abietis. Phylogenetic analysis of length polymorphisms and of 24 restriction sites in the SSU and ITS showed that Gremmeniella isolates were more related to each other than to the Ascocalyx isolate. Furthermore, seven groups were evident within the genus Gremmeniella. Our results confirm that Gremmeniella and Ascocalyx should be kept as different taxa and suggest that the taxonomy of the former could be revised to consider isolates from Abies balsamea and from Picea spp. to be two different varieties while incorporating Gremmeniella laricina into G. abietina, as a new variety.     

迈向纳米级芯片技术的IMEC研发——先进封装技术部分

近期、芯片制造工艺发展到了纳米时代(栅极宽度<100nm),IM E C发起并联合了全球七家主要半导体芯片制造商和几乎所有主要设备制造商,在刚建立起来的φ300m m硅片尺寸工艺中试线上,共同展开了45nm和32nm的芯片制造工艺的研究工作。虽然芯片封装技术也在快速发展,但其速度赶不上芯片制造工艺的迅猛发展。在先进的芯片制造技术和最新的PCB技术之间所谓的“互连技术壕沟”在不断扩大。而且,不断增加的工作频率,以及由于集成电路复杂程度提高而导致I O管脚的增加,都要求封装技术产生重大的技术变革,以保证在将纳米级的芯片与毫米级的系统相连…     

Data-parallel intra decoding for block-based image and video coding on massively parallel architectures

With the increasing number of processor cores available in modern computing architectures, task or data parallelism is required to maximally exploit the available hardware and achieve optimal processing speed. Current state-of-the-art data-parallel processing methods for decoding image and video bitstreams are limited in parallelism by dependencies introduced by the coding tools and the number of synchronization points introduced by these dependencies, only allowing task or coarse-grain data parallelism. In particular, entropy decoding and data prediction are bottleneck coding tools for parallel image and video decoding. We propose a new data-parallel processing scheme for block-based intra sample and coefficient prediction that allows fine-grain parallelism and is suitable for integration in current and future state-of-the-art image and video codecs. Our prediction scheme enables maximum concurrency, independent of slice or tile configuration, while minimizing synchronization points. This paper describes our data-parallel processing scheme for one- and two-dimensional prediction and investigates its application to block-based image and video codecs using JPEG XR and H.264/AVC Intra as a starting point. We show how our scheme enables faster decoding than the state-of-the-art wavefront method with speedup factors of up to 21.5 and 7.9 for JPEG XR and H.264/AVC Intra coding tools respectively. Using the H.264/AVC Intra coding tool, we discuss the requirements of the algorithm and the impact on decoded image quality when these requirements are not met. Finally, we discuss the impact on coding rate in order to allow for optimal parallel intra decoding.     

Coating quality as affected by core particle segregation in fluidized bed processing

Fluidized bed coating is an important technique in the food powder industry, where often particles of a wide size distribution are dealt with. In this paper, glass beads of different particle size distribution were coated with sodium caseinate in a top-spray fluid bed unit. Positron Emission Particle Tracking (PEPT) was used to visualize and quantify the particle motion in the fluidized bed. Confocal Laser Scanning Microscopy combined with image analysis were used to investigate the effect of core particle size and its distribution on the thickness and quality of the coating. Particle size significantly affected the thickness and quality of the coating, due to differences in the corresponding fluidization patterns, as corroborated by PEPT observations. As the particle size distribution becomes narrower, segregation is less likely to occur. This results in a thicker coating which is, however, less uniform compared to when cores of a wider particle size distribution are spray coated.     

Incidence and pathophysiological changes in chronic two-kidney hypertension in the dog

Unilateral renal artery plication in dogs reduced renal blood flow by 80% and produced a sustained elevation in arterial pressure whereas plasma renin activity increased for only 4 days. Sodium was retained for 3 days after plication, but this response is similar to that after a sham operation. Of seven dogs studied chronically, elevated arterial pressure was sustained for 27 days or longer in six animals. In three dogs hypertension continued for 2 mo before collateral vessels developed and arterial pressure fell; ligation of these collaterals restored hypertension. Arterial pressure was unaffected by an infusion of [1-sarcosine, 8-alanine] angiotensin II in chronic hypertensive dogs on a normal sodium intake. This angiotensin antagonist lowered arterial pressure after sodium depletion, but became ineffective following rapid sodium repletion. Chronic hypertensive dogs showed normal responses to deoxycorticosterone acetate. These findings suggest that the renin-angiotensin system is not critically involved in maintenace of chronic two-kidney renovascular hypertension in the dog. The data also show that the homeostatic role played by the renin-angiotensin system in the maintenance of arterial pressure remained intact in chronic hypertension.     

Synthesis and turnover of the regularly arranged surface protein of Acinetobacter sp. relative to the other components of the cell envelope

The formation of the components of the cell envelope of Acinetobacter sp. 199A was investigated by measuring the incorporation of [3H]leucine into protein, [14C]galactose into lipopolysaccharide, 32P into phospholipid, and [3H]diaminopimelic acid into peptidoglycan. Whereas the lipopolysaccharide and intrinsic protein of the outer membrane were stable, some of the regularly arranged surface protein, the alpha-protein, was lost into the growth medium. Only newly synthesized alpha-protein was lost. The peptidoglycan of the murein layer was also labile. Selective inhibition of the formation of individual components of the cell envelope with penicillin, chloramphenicol, and bacitracin showed that incorporation of protein into the outer membrane required the simultaneous formation of complete lipopolysaccharide. The converse was not true: protein synthesis was not required for lipopolysaccharide incorporation. Formation of the outer membrane and the murein layer proceeded independently.