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排序方式: 共有234条查询结果,搜索用时 15 毫秒
1.
Keith Kenney 《The Journal of communication》1994,44(1):100-105
2.
Tresadern P.A. Thies S.B. Kenney L.P.J. Howard D. Goulermas J.Y. 《Pervasive Computing, IEEE》2008,7(2):62-69
The clinical set-up tool integrates fast parameter selection and a user-friendly interface to help electrical muscle stimulators more efficiently treat patients with neurological injuries. A key challenge in increasing functional electrical stimulation systems' clinical acceptance is facilitating or automating parameter selection, optimization, and programming to make the underlying engineering transparent to the user. To this end, we present the clinical set-up tool (CST), a finite-state-machine-based controller that integrates accurate, automatic parameter optimization in an intuitive user interface. Unlike other approaches, we employ a numerical algorithm that uses real-life data and well-defined criteria to rapidly optimize parameter values. 相似文献
3.
Hodgins D. Bertsch A. Post N. Frischholz M. Volckaerts B. Spensley J. Wasikiewicz J.M. Higgins H. von Stetten F. Kenney L. 《Pervasive Computing, IEEE》2008,7(1):14-21
Healthy Aims is a 23- million, four-year project, funded under the EU's information society technology sixth framework program to develop intelligent medical implants and diagnostic systems (www.healthyaims.org). The project has 25 partners from 10 countries, including commercial, clinical, and research groups. This consortium represents a combination of disciplines to design and fabricate new medical devices and components as well as to test them in laboratories and subsequent clinical trials. The project focuses on medical implants for nerve stimulation and diagnostic equipment based on strain-gauge technology. 相似文献
4.
Da Via C. Deile M. Hasi J. Kenney C. Kok A. Parker S. Watts S. Anelli G. Avati V. Bassetti V. Boccone V. Bozzo M. Eggert K. Ferro F. Inyakin A. Kaplon J. Bahilo J.L. Morelli A. Niewiadomski H. Noschis E. Oljemark F. Oriunno M. Osterberg K. Ruggiero G. Snoeys W. Tapprogge S. 《IEEE transactions on nuclear science》2009,56(2):505-518
3D detectors with electrodes penetrating through the silicon wafer and covering the edges were tested in the SPS beam line X5 at CERN in autumn 2003. Detector parameters including efficiency, signal-to-noise ratio, and edge sensitivity were measured using a silicon telescope as a reference system. The measured sensitive width and the known silicon width were equal within less than 10 mum. 相似文献
5.
Altering the association properties of insulin by amino acid replacement 总被引:12,自引:0,他引:12
Brems David N.; Alter Leila A.; Beckage Michael J.; Chance Ronald E.; DiMarchi Richard D.; Green L. Kenney; Long Harlan B.; Pekar Allen H.; Shields James E.; Frank Bruce H. 《Protein engineering, design & selection : PEDS》1992,5(6):527-533
The importance of ProB28 and LysB29 on the self-associationof insulin was established by systematically truncating theC terminus of the B chain. The relationship between structureand association was further explored by making numerous aminoacid replacements at B28 and B29 Association was studied bycircular dichroism, size-exclusion chromatography and ultracentrifugation.Our results show that the location of a prolyl residue at B28is critical for high-affinity self-association. Removal of ProB28in a series of C-terminal truncated insulins, or amino acidreplacement of Pro28, greatly reduced association. The largestdisruption to association was achieved by replacing LysB29 withPro and varying the amino acid at B28 Several of the analogswere predominantly monomers in solutions up to 3 mg/ml. Theseamino acid substitutions decreased association by primarilydisrupting the formation of dimers. Such amino acid substitutionsalso substantially reduced the Zn-induced insulin hexamer formation.The formation of monomeric insulins through amino acid replacementswas accompanied by conformational changes that may be the causefor decreased association. It is demonstrated that self-associationof insulin can be drastically altered by substitution of oneor two key amino acids. 相似文献
6.
Pressure-sensitive acrylic adhesives for application to skin are made from 2-ethylhexyl acrylate, isooctyl acrylate or n-butyl acrylate copolymerized with polar functional monomers such as acrylic acid, methacrylic acid, vinyl acetate, methyl acrylate, N-vinylcaprolactam, or hydroxyethyl methacrylate. Functional comonomers increase cohesive strength, provide surface polarity, and enhance wear performance. Tack, adhesion to skin, adhesive transfer to skin, and wear performance of the adhesive are governed by the molecular weight, glass transition temperature, and the viscoelastic behavior of the adhesive. Viscoelastic properties of the adhesive as measured by the Williams plasticity number (WPN), dynamic storage modulus (G′), dynamic loss modulus (G″), and tan δ are important polymer properties for good wear performance. Sweating skin, a moist environment, and physical activity are the most important factors influencing the failure of an adhesive tape during wear. A medicalgrade adhesive for application to human skin should be hypoallergenic. Medical-grade adhesives are utilized in making surgical tapes for holding dressings in place, adhesive bandages, adhesive dressings to cover wounds, and surgical operating drapes. 相似文献
7.
Myofibrillar Protein Solubility of Model Beef Batters as Affected by Low Levels of Calcium, Magnesium and Zinc Chloride 总被引:1,自引:0,他引:1
Preblended composites of semimembranosus and adductor muscles were stored 12h at 4°C with 2.0% NaCl, 0 or 0.05% CaCl2, MgCl2, or ZnCl2 and 0 or 0.4% sodium tripolyphosphate (STPP). Model systems were formulated to contain 30% fat (high fat; HF) or 10% fat (low fat; LF). Divalent salts lowered extract pH and ZnCl2 elicited the greatest reduction. At both fat levels, CaCl2 increased and ZnCl2 decreased protein solubility, compared to the control (p<0.05). Myosin was not detected in ZnCl2-treated HF and LF batters without STPP and in the presence of STPP, MgCl2 and ZnCl2 increased myosin concentration at both fat levels (p<0.05). Zinc chloride increased actin concentration in HF batters; whereas, MgCl2 decreased soluble actin in LF batters (p<0.05). Magnesium chloride (0.05%) increased soluble proteins in LF batters containing 0.4% STPP by increasing myosin extractability. 相似文献
8.
Kenney CJ Segal JD Westbrook E Parker S Hasi J Da Via C Watts S Morse J 《Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment》2006,565(1):272-277
Many systems in medicine, biology, high-energy physics, and astrophysics require large area radiation sensors. In most of these applications, minimizing the amount of dead area or dead material is crucial. We have developed a new type of silicon radiation sensor in which the device is active to within a few microns of the mechanical edge. Their perimeter is made by a plasma etcher rather than a diamond saw. Their edges can be defined and also passivated by growing, in an intermediate step, a field oxide on the side surfaces. In this paper, the basic architecture and results from a synchrotron beam test are presented. 相似文献
9.
Weinlaender M. Beumer J. Kenney E. B. Moy P. K. Adar F. 《Journal of materials science. Materials in medicine》1992,3(6):397-401
The purpose of the current study was to evaluate the crystallographic properties of three commercially plasma-flame-sprayed hydroxyapatite (HAp) coatings on dental implants. For this purpose a Raman microprobe (MOLE U1000) was used. No preparation of the surfaces was necessary to examine the thin ceramic surface layers. Microspectra (5 µm) and macrospectra (100 µm) have been measured and compared to the spectra of crystalline and amorphous HAp as well as to the spectra of tricalciumphosphate. All implants showed spectra that were more like that of the amorphous phase of HAp than any of the other examined reference materials. However, the implant spectra exhibited an extra band that as yet has not been identified. This band is probably indicative of some structure within the sprayed amorphous phase. Such structural effects would result either directly from quenching from the plasma state or by incorporation of titanium into the lattice during plasma treatment. 相似文献
10.