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排序方式: 共有293条查询结果,搜索用时 46 毫秒
1.
Luc Rochette Loubna Mazini Gabriel Malka Marianne Zeller Yves Cottin Catherine Vergely 《International journal of molecular sciences》2020,21(23)
The potential use of stem cell-based therapies for the repair and regeneration of various tissues and organs is a major goal in repair medicine. Stem cells are classified by their potential to differentiate into functional cells. Compared with other sources, adipose-derived stem cells (ADSCs) have the advantage of being abundant and easy to obtain. ADSCs are considered to be tools for replacing, repairing, and regenerating dead or damaged cells. The capacity of ADSCs to maintain their properties depends on the balance of complex signals in their microenvironment. Their properties and the associated outcomes are in part regulated by reactive oxygen species, which mediate the oxidation-reduction state of cells as a secondary messenger. ADSC therapy has demonstrated beneficial effects, suggesting that secreted factors may provide protection. There is evidence that ADSCs secrete a number of cytokines, growth factors, and antioxidant factors into their microenvironment, thus regulating intracellular signaling pathways in neighboring cells. In this review, we introduce the roles of ADSCs in the protection of cells by modulating inflammation and immunity, and we develop their potential therapeutic properties. 相似文献
2.
Dealing with discrepancies in data is still a big challenge in data integration systems. The problem occurs both during eliminating duplicates from semantic overlapping sources as well as during combining complementary data from different sources. Though using SQL operations like grouping and join seems to be a viable way, they fail if the attribute values of the potential duplicates or related tuples are not equal but only similar by certain criteria. As a solution to this problem, we present in this paper similarity-based variants of grouping and join operators. The extended grouping operator produces groups of similar tuples, the extended join combines tuples satisfying a given similarity condition. We describe the semantics of this operator, discuss efficient implementations for the edit distance similarity and present evaluation results. Finally, we give examples of application from the context of a data reconciliation project for looted art. 相似文献
3.
Rehana Yasmin Eike Ritter Guilin Wang 《International Journal of Information Security》2014,13(5):453-465
Designing efficient as well as secure cryptographic protocols for resource-constrained applications is a challenging task. In this paper, we formally analyze the security of an efficient one-pass authenticated key establishment protocol, the 1P-AKE protocol, which is primarily proposed for resource-constrained sensor nodes devices in wireless sensor networks (WSNs). In contrast to the existing identity-based one-pass key establishment protocols, the 1P-AKE protocol does not require any bilinear pairing computation in order to establish a key. This feature makes it really attractive for resource-constrained application environments, such as WSNs, where pairing computations are too expensive. We show that in the random oracle model, the 1P-AKE protocol is a secure authenticated one-pass key establishment protocol under the computational Diffie–Hellman assumption. The performance of the 1P-AKE protocol is also discussed and compared with the existing relevant protocols. 相似文献
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5.
Andreas Zeller 《Datenschutz und Datensicherheit - DuD》2016,40(8):519-522
Moderne Testgeneratoren finden Schwachstellen in Eingabeschnittstellen von Programmen, indem sie in Sekunden tausende Eingaben zufällig erzeugen. Die Werkzeuge lassen sich leicht von jedermann einsetzen–zum Angriff oder zur Verteidigung. 相似文献
6.
Aminuddin A. Kayani Adam F. Chrimes Khashayar Khoshmanesh Vijay Sivan Eike Zeller Kourosh Kalantar-zadeh Arnan Mitchell 《Microfluidics and nanofluidics》2011,11(1):93-104
This work demonstrates an optofluidic system, where dielectrophoretically controlled suspended nanoparticles are used to manipulate
the properties of an optical waveguide. This optofluidic device is composed of a multimode polymeric rib waveguide and a microfluidic
channel as its upper cladding. This channel integrates dielectrophoretic (DEP) microelectrodes and is infiltrated with suspended
silica and tungsten trioxide nanoparticles. By applying electrical signals with various intensities and frequencies to the
DEP microelectrodes, the nanoparticles can be concentrated close to the waveguide surface significantly altering the optical
properties in this region. Depending on the particle refractive indices, concentrations, positions and dimensions, the light
remains confined or is scattered into the surrounding media in the microfluidic channel. 相似文献
7.
Termeer M Oliván Bescós J Breeuwer M Vilanova A Gerritsen F Gröller ME Nagel E 《IEEE transactions on visualization and computer graphics》2008,14(6):1595-1602
Visually assessing the effect of the coronary artery anatomy on the perfusion of the heart muscle in patients with coronary artery disease remains a challenging task. We explore the feasibility of visualizing this effect on perfusion using a numerical approach. We perform a computational simulation of the way blood is perfused throughout the myocardium purely based on information from a three-dimensional anatomical tomographic scan. The results are subsequently visualized using both three-dimensional visualizations and bull's eye plots, partially inspired by approaches currently common in medical practice. Our approach results in a comprehensive visualization of the coronary anatomy that compares well to visualizations commonly used for other scanning technologies. We demonstrate techniques giving detailed insight in blood supply, coronary territories and feeding coronary arteries of a selected region. We demonstrate the advantages of our approach through visualizations that show information which commonly cannot be directly observed in scanning data, such as a separate visualization of the supply from each coronary artery. We thus show that the results of a computational simulation can be effectively visualized and facilitate visually correlating these results to for example perfusion data. 相似文献
8.
A formal model of atomicity in asynchronous systems 总被引:1,自引:0,他引:1
Summary We propose a generalisation of occurrence graphs as a formal model of computational structure. The model is used to define the atomic occurrence of a program, to characterise interference freeness between programs, and to model error recovery in a decentralised system. 相似文献
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