Spectral Measurement of the Film-Substrate Index Difference in Proton-Exchanged LiNbO(3) Waveguides

We report the spectral characterization of proton-exchanged lithium niobate (PE:LiNbO(3)) waveguides in terms of the variation of the refractive-index difference between the waveguiding layer and the substrate. The dispersion of the extraordinary refractive-index increase (deltan(e)) is measured from 405 to 1319 nm with several light sources. Two types of proton-exchanged waveguide, prepared under different conditions, are studied. These measurements should be of use in the optimization of PE:LiNbO(3) waveguides for nonlinear optical applications, particularly in second-harmonic generation in the blue-green wavelength region.     

Relaxed constraints support vector machines for noisy data

Real-world data collected for computer-based applications are frequently impure. Differentiation of outliers and noisy data from normal ones is a major task in data mining applications. On the other hand, elimination of noisy and outlier data from training samples of a dataset may lead to over-fitting or information loss. A fuzzy support vector machine (FSVM) provides an effective means to deal with this problem. It reduces the effect of the noisy data and outliers by using a fuzzy membership functions. In this paper, a new formation for SVMs is introduced that considers importance degrees for training samples. The constraints of the SVM are converted to fuzzy inequalities. The proposed method, RSVM, shows better efficiency in the classification of data in different domains. Especially, using the proposed RSVM for multi-class classification of arrhythmia disease is presented at the end of this paper as a practical case study to show the effectiveness of the proposed system.     

Adaptation of Oxidative Phosphorylation Machinery Compensates for Hepatic Lipotoxicity in Early Stages of MAFLD

Alterations in mitochondrial function are an important control variable in the progression of metabolic dysfunction-associated fatty liver disease (MAFLD), while also noted by increased de novo lipogenesis (DNL) and hepatic insulin resistance. We hypothesized that the organization and function of a mitochondrial electron transport chain (ETC) in this pathologic condition is a consequence of shifted substrate availability. We addressed this question using a transgenic mouse model with increased hepatic insulin resistance and DNL due to constitutively active human SREBP-1c. The abundance of ETC complex subunits and components of key metabolic pathways are regulated in the liver of these animals. Further omics approaches combined with functional assays in isolated liver mitochondria and primary hepatocytes revealed that the SREBP-1c-forced fatty liver induced a substrate limitation for oxidative phosphorylation, inducing enhanced complex II activity. The observed increased expression of mitochondrial genes may have indicated a counteraction. In conclusion, a shift of available substrates directed toward activated DNL results in increased electron flows, mainly through complex II, to compensate for the increased energy demand of the cell. The reorganization of key compounds in energy metabolism observed in the SREBP-1c animal model might explain the initial increase in mitochondrial function observed in the early stages of human MAFLD.     

Thermal and rheological properties of nanoparticle modified asphalt binder at low and intermediate temperature range

There is a paucity of knowledge regarding the effect of nanoparticles on the performance of asphalt binder against fatigue and low-temperature cracking. In this research, asphalt binders were modified using SiO₂, TiO₂, and CaCO₃ nanoparticles, and rheological and thermal properties of the modified binders were investigated. Differential scanning calorimetry was used to determine glass transition temperature, and rheological properties at low and intermediate temperatures were determined using bending beam and dynamic shear rheometers, respectively. The results suggested that the addition of these nanoparticles increases glass transition temperature and the low-temperature stiffness of asphalt binder. Furthermore, increase in complex shear modulus and decrease in phase angle values were observed at intermediate temperatures. It can be concluded that inferior performance at low and intermediate temperature is expected by the addition of nanoparticles to asphalt binder.     

Investigation of Crosstalk and Coupling Effects of Incident Plane Waves in Orthogonal Microstrips in High-Speed Integrated Circuits Using Full-Wave and Quasi-Static Methods

The crosstalk and coupling of the external fields on orthogonal microstrip transmission lines in different layers have significant effects on signal quality in MMIC and PCBs. In this paper the crosstalk is analyzed in detail using both full-wave and quasi-static methods. The used full wave method is mixed potential integral equation method of moment (MPIEMoM). Because of the weak coupling between lines, the effect of the incident plane-wave is studied by applying transmission line theory in a scattered voltage formulation uses quasi-TEM propagation model for each interconnection and the exact distribution of the incident electric field within the layers. Afterward, by using the predetermined lumped circuit model of the cross-region, the effect of coupling between two lines is calculated and then applied to terminal voltages in 1–20 GHz frequency range which results in the final terminal voltages.     

A Dempster–Shafer Based Tit-for-Tat Strategy to Regulate the Cooperation in VANET Using QoS-OLSR Protocol

In this paper, we address the problem of cooperation among vehicles in VANET using QoS-OLSR protocol in the presence of selfish nodes. QoS-OLSR is a proactive protocol that considers the Quality of Service (QoS) of the nodes while electing the cluster-heads and selecting the Multi-Point Relay (MPRs) nodes. Cluster-heads and MPRs might misbehave on the roads by over-speeding or under-speeding. Classical and generous Tit-for-Tats are proposed to analyze the interaction among vehicles. However, both strategies are not able to enforce the cooperation due the fact that they (1) count on individual watchdogs monitoring, (2) rely on the node-to-node cooperation decision, (3) and ignore the high mobility and packet collisions. Therefore, we propose a Dempster–Shafer based Tit-for-Tat strategy that is able to improve the decision and regulate the cooperation in the vehicular network. This is done by (1) launching a cooperative watchdogs monitoring, (2) correlating the observations of the different watchdogs using Dempster–Shafer theory, and (3) propagating the decisions among clusters. Thereafter, we compare the Dempster–Shafer based strategy with several strategies derived from the original Tit-for-Tat. Simulation results prove that the Dempster–Shafer based strategy is able to maintain the survivability of the vehicular network in the presence of high mobility and packet collisions with minimal time and overhead.     

A Finite Volumes-Based 3-D Low Dispersion FDTD Algorithm

An algorithm extension to three dimensions is developed and presented for the highly phase-coherent modified second-order in time, fourth-order in space (or M24) finite-difference time-domain (FDTD) algorithm. A finite-volumes approach in conjunction with Yee's standard FDTD lattice is used for algorithm development. The corresponding dispersion relation is also developed, analyzed and compared to both the standard second-order and fourth-order FDTD algorithms as well as to two closely related high-order phase-coherent algorithms. Wideband algorithm attributes are also presented as well as sets of ready to use optimized algorithm coefficients.     

Yellow–Orange Electroluminescence of Novel Tin Complexes

Novel tin complexes were synthesized for use as fluorescent materials in organic light-emitting diodes (OLEDs). The structures of these complexes were characterized by ultraviolet–visible, Fourier-transform infrared, and nuclear magnetic resonance spectroscopy methods and elemental analyses. The energy levels of the tin complexes were determined using cyclic voltammetry measurements. Devices were fabricated with an indium tin oxide (ITO)/PEDOT:PSS (90 nm)/PVK:PBD:tin complexes (75 nm)/Al (180 nm) structure; the resultant devices had peak emissions ranging from 537 nm to 580 nm. The tin complexes accounted for 8 wt.% of the blend in the PVK:PBD (100:40), which was used as a host. The electroluminescent spectra of the tin complexes were red-shifted as compared with the PVK:PBD blend. We believe that the electroluminescence performance of OLED devices based on tin complexes relies on overlaps between the absorption of the tin compounds and the emission of PVK:PBD.     

Compressive sensing based high-resolution passive bistatic radar

Passive bistatic radar (PBR) systems using different communication signals can only offer low-resolution target detection due to their inherent low bandwidth. In this paper, compressive sensing (CS) is applied to multichannel FM and GSM PBR to achieve improved range-Doppler resolutions and avoid some limitations of classical multiband PBR processing. In CS context, block-structured time-domain dictionary which is formed from multichannel signals suffers from coherence when fine range resolution is employed. To overcome such a pitfall, this work first transforms the dictionary to spectral domain where only the most important spectral components are retained. Principle component analysis followed by a whitening method are then applied to this spectrally transformed data in order to reduce the dimensionality of problem, thereby reducing the dictionary size and most importantly fulfilling the required condition of dictionary incoherence for better CS-based recovery. Two different block-structured dictionary formations are tested. The performance of the recovery of spatially close targets, in both FM and GSM PBR setups, are reported.     

Hybrid Paper–Plastic Microchip for Flexible and High‐Performance Point‐of‐Care Diagnostics

A low‐cost and easy‐to‐fabricate microchip remains a key challenge for the development of true point‐of‐care (POC) diagnostics. Cellulose paper and plastic are thin, light, flexible, and abundant raw materials, which make them excellent substrates for mass production of POC devices. Herein, a hybrid paper–plastic microchip (PPMC) is developed, which can be used for both single and multiplexed detection of different targets, providing flexibility in the design and fabrication of the microchip. The developed PPMC with printed electronics is evaluated for sensitive and reliable detection of a broad range of targets, such as liver and colon cancer protein biomarkers, intact Zika virus, and human papillomavirus nucleic acid amplicons. The presented approach allows a highly specific detection of the tested targets with detection limits as low as 10² ng mL^?1 for protein biomarkers, 10³ particle per milliliter for virus particles, and 10² copies per microliter for a target nucleic acid. This approach can potentially be considered for the development of inexpensive and stable POC microchip diagnostics and is suitable for the detection of a wide range of microbial infections and cancer biomarkers.