Visualization of Back Pain Data—A 3-D Solution

Traditional approaches to gathering and visualizing pain data rely on two-dimensional (2-D) human body models, where different types of sensation are recorded with various monochrome symbols. We propose an alternative that uses a three-dimensional (3-D) representation of the human body, which can be marked in color to visualize and record pain data.     

Methamphetamine impairs sexual motivation but not sexual performance in male Japanese quail.

The present study investigated the effects of chronic pre-exposure to methamphetamine on sexual motivation and performance in male Japanese quail. Quail were pre-exposed to methamphetamine (1.0 or 3.0 mg/kg ip) or saline (ip) once daily for 10 days and locomotor activity was measured. After a 10 day washout period, sexual motivation was measured in a straight-arm runway with visual access to a female at one end. Three to 5 hr after sexual motivation tests, males were allowed to copulate with a receptive female quail and copulatory behavior was assessed. Tests were conducted once per day for 10 days. Results showed that males pre-exposed to methamphetamine had decreased locomotor activity compared to saline controls. Males pre-exposed to METH later ran slower toward a female in the runway and spent less time near her. In contrast, methamphetamine pre-exposed males showed similar copulatory behavior as saline pre-exposed males. The findings suggest that chronic pre-exposure to methamphetamine may impair sexual motivation but not sexual performance. The findings are discussed from a comparative perspective and with regard to their clinical relevance. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

A novel hybridized metaheuristic technique in enhancing the diagnosis of cross-sectional dent damaged offshore platform members

Offshore jacket platforms are widely used for oil and gas extraction as well as transportation in shallow to moderate water depth. Tubular cross-sectional elements are used to construct offshore platforms. Tubular cross sections impart higher resistance against hydrodynamic forces and have high torsional rigidity. During operation, the members can be partially or fully damaged due to lateral impacts. The lateral impacts can be due to ship collisions or through the impact of falling objects. The impact forces can weaken some members that influence the overall performance of the platform. This demonstrates an urgent need to develop a framework that can accurately forecast dent depth as well as dent angle of the affected members. This study investigates the use of an adaptive metaheuristics algorithm to provide automatic detection of denting damage in an offshore structure. The damage information includes dent depth and the dent angle. A model is developed in combination with the percentage of the dent depth of the damaged member and is used to assess the performance of the method. It demonstrates that small changes in stiffness of individual damaged bracing members are detectable from measurements of global structural motion.     

Cloud based intelligent system for delivering health care as a service

The promising potential of cloud computing and its convergence with technologies such as mobile computing, wireless networks, sensor technologies allows for creation and delivery of newer type of cloud services. In this paper, we advocate the use of cloud computing for the creation and management of cloud based health care services. As a representative case study, we design a Cloud Based Intelligent Health Care Service (CBIHCS) that performs real time monitoring of user health data for diagnosis of chronic illness such as diabetes. Advance body sensor components are utilized to gather user specific health data and store in cloud based storage repositories for subsequent analysis and classification. In addition, infrastructure level mechanisms are proposed to provide dynamic resource elasticity for CBIHCS. Experimental results demonstrate that classification accuracy of 92.59% is achieved with our prototype system and the predicted patterns of CPU usage offer better opportunities for adaptive resource elasticity.     

Artificial bee colony based energy‐aware resource utilization technique for cloud computing

Cloud computing is a form of distributed computing, which promises to deliver reliable services through next‐generation data centers that are built on virtualized compute and storage technologies. It is becoming truly ubiquitous and with cloud infrastructures becoming essential components for providing Internet services, there is an increase in energy‐hungry data centers deployed by cloud providers. As cloud providers often rely on large data centers to offer the resources required by the users, the energy consumed by cloud infrastructures has become a key environmental and economical concern. Much energy is wasted in these data centers because of under‐utilized resources hence contributing to global warming. To conserve energy, these under‐utilized resources need to be efficiently utilized and to achieve this, jobs need to be allocated to the cloud resources in such a way so that the resources are used efficiently and there is a gain in performance and energy efficiency. In this paper, a model for energy‐aware resource utilization technique has been proposed to efficiently manage cloud resources and enhance their utilization. It further helps in reducing the energy consumption of clouds by using server consolidation through virtualization without degrading the performance of users’ applications. An artificial bee colony based energy‐aware resource utilization technique corresponding to the model has been designed to allocate jobs to the resources in a cloud environment. The performance of the proposed algorithm has been evaluated with the existing algorithms through the CloudSim toolkit. The experimental results demonstrate that the proposed technique outperforms the existing techniques by minimizing energy consumption and execution time of applications submitted to the cloud. Copyright © 2014 John Wiley & Sons, Ltd.     

A review of the air oxidation of aqueous sulphide solutions

The oxidation by air or oxygen of aqueous solutions of sulphides is reviewed. Some additional data obtained by the authors is also included. A hypothesis is advanced explaining the widely accepted catalytic effects operative in this reaction in terms of a coupled pair of electrochemical reactions.     

Novel Peptide‐Heterocycle Hybrids: Synthesis and Preliminary Studies on Calpain Inhibition

New peptidic compounds, having peptide chains linked to bi‐ and tricyclic heterocycles (peptide‐heterocycle hybrids), have been synthesized. The heterocyclic components are derivatives of partially reduced isoquinoline and pyrido[1,2‐b]isoquinoline bearing α,β‐unsaturated carbonyl functionalities. The heterocyclic compounds have been used as acylating agents in coupling reactions with short N‐unprotected peptides. Based on our interest on potential calpain inhibitors, we have used short (2–4 amino acids) peptides with hydrophobic amino acids of the two enantiomeric series. We report preliminary studies on the inhibition of calpain, with some compounds having IC₅₀ values in the nanomolar range.     

Reliability-based settlement analysis of embankments over soft soils reinforced with T-shaped deep cement mixing piles

This paper presents a reliability-based settlement analysis of T-shaped deep cement mixing (TDM) pile-supported embankments over soft soils. The uncertainties of the mechanical properties of the in-situ soil, pile, and embankment, and the effect of the pile shape are considered simultaneously. The analyses are performed using Monte Carlo Simulations in combination with an adaptive Kriging (using adaptive sampling algorithm). Individual and system failure probabilities, in terms of the differential and maximum settlements (serviceability limit state (SLS) requirements), are considered. The reliability results for the embankments supported by TDM piles, with various shapes, are compared and discussed together with the results for conventional deep cement mixing pile-supported embankments with equivalent pile volumes. The influences of the inherent variabilities in the material properties (mean and coefficient of variation values) on the reliability of the piled embankments, are also investigated. This study shows that large TDM piles, particularly those with a shape factor of greater than 3, can enhance the reliability of the embankment in terms of SLS requirements, and even avoid unacceptable reliability levels caused by variability in the material properties.     

Prenatal determination of human platelet antigen type using DNA amplification following amniocentesis

OBJECTIVE: To assess the effectiveness of a newly developed individualised birthweight ratio (IBR), which corrects for physiological birthweight determinants, in identifying infants at risk from the complications of macrosomia. DESIGN: Prospective observational study. SETTING: Obstetric unit, Nottingham City Hospital. SUBJECTS: 2835 women delivered between December 1991 and July 1992 and the infants of 624 of these, selected by virtue of their birthweight for gestation and IBR centile positions. MAIN OUTCOME MEASURES: Skinfold thickness and ponderal index measurements, operative delivery, shoulder dystocia, fetal trauma, impaired glucose tolerance. RESULTS: Using an IBR above the 90th centile as a cut off results in 2.4% of infants being reclassified as normally grown and 3.1% are reclassified as large. The IBR does not result in the identification of any more infants with abnormal ponderal indices or skinfold thicknesses than birthweight for gestation. It does, however, identify more of the infants at risk of operative delivery, shoulder dystocia, fetal trauma and impaired glucose tolerance. CONCLUSION: The IBR significantly improves upon birthweight for gestation in identifying infants who suffer from the complications of relative macrosomia.