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排序方式: 共有101条查询结果,搜索用时 10 毫秒
1.
Bravo-Montes J. A. Martín-Toledano A. Sánchez-Macián A. Ruano O. Garcia-Herrero F. 《The Journal of supercomputing》2022,78(6):8056-8080
The Journal of Supercomputing - CMOS technology is facing physical limitations in scaling the manufacturing process. Therefore, to deepen the development of better designs in a smaller area, it is... 相似文献
2.
Catalyst substrate foils of the highly oxidation resistant Fe-25Cr-5Al alloy (mass contents in %) with a thickness ranging from 40 to 180 μm have been produced by planar flow casting. The rapidly solidified ribbons showed a monophase ferritic microstructure of columnar grains. The grain size determined over a section parallel to the ribbon wheel side ranged from 5 μm for the thin ribbons (40 μm) to 18 μm for the thicker ones {180 μm). This anisotropic columnar solidification microstructure exhibits a strong <100> fiber texture, with the fiber axis nearly perpendicular to the plane of the ribbon. The position of the maximum in the pole figure was tilted from the center point toward the casting direction. Results of uniaxial tensile tests showed that only the yield stress data of the ribbons in the as-cast condition are reproducible, whereas the ultimate tensile strength and the elongation to failure data show a wide scatter band. The fracture mode exhibits ductile features such as glide bands and dimples. 相似文献
3.
Silva Khodjoyan Deborha Morissette Fortune Hontonnou Luis Checa Ruano Charles-Adrien Richard Olivier Sperandio Jean-Franois Elouët Marie Galloux Philippe Durand Stphanie Deville-Foillard Christina Sizun 《International journal of molecular sciences》2023,24(1)
The interaction between Respiratory Syncytial Virus phosphoprotein P and nucleoprotein N is essential for the formation of the holo RSV polymerase that carries out replication. In vitro screening of antivirals targeting the N-P protein interaction requires a molecular interaction model, ideally consisting of a complex between N protein and a short peptide corresponding to the C-terminal tail of the P protein. However, the flexibility of C-terminal P peptides as well as their phosphorylation status play a role in binding and may bias the outcome of an inhibition assay. We therefore investigated binding affinities and dynamics of this interaction by testing two N protein constructs and P peptides of different lengths and composition, using nuclear magnetic resonance and fluorescence polarization (FP). We show that, although the last C-terminal Phe241 residue is the main determinant for anchoring P to N, only longer peptides afford sub-micromolar affinity, despite increasing mobility towards the N-terminus. We investigated competitive binding by peptides and small compounds, including molecules used as fluorescent labels in FP. Based on these results, we draw optimized parameters for a robust RSV N-P inhibition assay and validated this assay with the M76 molecule, which displays antiviral properties, for further screening of chemical libraries. 相似文献
4.
5.
César A Teixeira Maria Gra?a Ruano António E Ruano Wagner C A Pereira 《IEEE transactions on bio-medical engineering》2008,55(2):572-580
The safe and effective application of thermal therapies is restricted due to lack of reliable noninvasive temperature estimators. In this paper, the temporal echo-shifts of backscattered ultrasound signals, collected from a gel-based phantom, were tracked and assigned with the past temperature values as radial basis functions neural networks input information. The phantom was heated using a piston-like therapeutic ultrasound transducer. The neural models were assigned to estimate the temperature at different intensities and points arranged across the therapeutic transducer radial line (60 mm apart from the transducer face). Model inputs, as well as the number of neurons were selected using the multiobjective genetic algorithm (MOGA). The best attained models present, in average, a maximum absolute error less than 0.5 degrees C, which is pointed as the borderline between a reliable and an unreliable estimator in hyperthermia/diathermia. In order to test the spatial generalization capacity, the best models were tested using spatial points not yet assessed, and some of them presented a maximum absolute error inferior to 0.5 degrees C, being "elected" as the best models. It should be also stressed that these best models present implementational low-complexity, as desired for real-time applications. 相似文献
6.
7.
The high-temperature deformation behavior of a dispersion-strengthened Al-8.4Fe-3.6Ce material studied by Yaney and Nix[1] has been reanalyzed using concepts used in the analysis of the creep behavior of Al-Fe-V-Si materials. The Al-8.4Fe-3.6Ce
material presents a high volume fraction of submicron dispersoids. The stress exponent and the activation energy values are
anomalously high-temperature dependent, as it is usually found in most reinforced materials. Although the creep behavior of
this material has been described by the deformation of dispersoids, however, direct evidence of the deformation of the second-phase
precipitates was not obtained. In this work, a new approach is further developed. This approach is based on the constant substructure
slip creep equation modified by the presence of an interaction between dislocations and dispersoids. This approach is able
to satisfactorily predict the creep behavior of the Al-8.4Fe-3.6Ce material. 相似文献
8.
Silvia Baena‐Ruano Carlos Jiménez‐Ot Inés M. Santos‐Dueñas Jorge E. Jiménez‐Hornero José L. Bonilla‐Venceslada Carmen Álvarez‐Cáliz Isidoro García‐García 《Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986)》2010,85(7):908-912
BACKGROUND: The acetification process needs an overall study of the variables influencing it in order to establish their optimum values. Based on industrial experience and available literature, including a recently proposed model by the authors, among the variables most strongly influencing the acetification process are the ethanol concentration at the time the reactor is unloaded, the unloaded volume and the loading rate. To ensure economically efficient industrial production of vinegar, and to check the predictions of the aforementioned model, the influence of the final ethanol concentration at unloading time on the mean acetification rate and on productivity has been studied in this work. RESULTS: An increase in the final ethanol concentration from 0.5 to 3.5% (v/v) increased the mean overall acetification rate and acetic acid production by 38 and 26%, respectively. The increase was established mainly during the loading phase. CONCLUSIONS: The final ethanol concentration is a key variable for process optimization. If a high rate is desired then a product containing much unused substrate will be obtained, which may be industrially unacceptable. These results suggest the necessity to investigate other possibilities when high values for yield and productivity must to be achieved. Copyright © 2010 Society of Chemical Industry 相似文献
9.
Rieiro Ignacio Carsí Manuel Ruano Oscar A. 《Metallurgical and Materials Transactions A》2017,48(7):3445-3460
Metallurgical and Materials Transactions A - In the present work, a new stability criterion is presented that uses the single sine hyperbolic equation of Garofalo for all values of the... 相似文献
10.
G. Ruano J. Ferrón 《Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms》2008,266(22):4888-4890
We present measurements of secondary electron emission from Cu induced by low energy bombardment (1-5 keV) of noble gas (He+, Ne+ and Ar+) and Li+ ions. We identify different potential and kinetic mechanisms and find the presence of high energetic secondary electrons for a couple of ion-target combinations. In order to understand the presence of these fast electrons we need to consider the Fermi shuttle mechanism and the different ion neutralization efficiencies. 相似文献