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991.
    
Human airway tree segmentation from computed tomography (CT) images is a very important step for virtual bronchoscopic applications. Imaging artifacts or thin airway walls decrease the contrast between the air and airway wall and make the segmented region to leak from inside of the airway to the parenchyma. This in turn begins the leakage phenomenon to build and then large parts of the lung parenchyma might be erroneously marked as the airway tree instead. Unfortunately, existing methods typically do not sufficiently extract the necessary peripheral airways needed to plan a procedure. In this article, we propose a new shape based human airway segmentation scheme to suppress the leakage into surrounding area which is based on fuzzy connectivity (FC) method. Complex medical image features such as weak boundary edges in the CT images of the lung parenchyma have fuzzy properties and can be described by FC in many extents. Our method aims to embed a mathematical shape optimization approach in a FC algorithm. Using the partial derivatives of the image data that is minimized with respect to the polar angle and cylindrical axis direction, a proper cost function based on cylindrical features of the airway branches is proposed. This approach retains the cylindrical properties of the airway branches during the segmentation process. The proposed cost function includes two parts named cylindrical‐shape feature and smoothed final error term. The former term arranges the underlying voxels on a cylindrical shape and the latter term controls and smoothes the final error considering the local minima's problem. To evaluate the efficiency of our proposed optimization technique in term of segmentation accuracy, the cost function is first applied to the simulated data with the spongy shape of leakage and the leakage origin. The impact of each term of the proposed cost function on the final error and the convergence of the algorithm are also evaluated. Then, the cost function with best proper parameters is applied to real image dataset. Comparisons of the results on multidetector CT chest scans show that our segmentation algorithm outperforms the fuzzy region growing algorithm. Quantitative comparisons with manually segmented airway trees also indicate high sensitivity of our segmentation algorithm on peripheral airways. On the basis of the results, it is concluded that the proposed method is able to detect more branches up to the sixth generation with no leakage which provides 2–3 more generations of airways than several other methods do. The extracted airway trees enable image‐guided bronchoscopy to go deeper into the human lung periphery than past studies. The novelty of our proposed method is to apply a shape optimization approach embedded in an efficient FC segmentation algorithm. Hence, our method prevents leakage from its origination in contrast to most previously published works that just set their algorithms to repeat the segmentation steps to reduce leakage. As our results indicate leakage suppression in human airway segmentation instead of readjusting the segmentation parameters, more airway branches can be extracted with correct shape. © 2013 Wiley Periodicals, Inc. Int J Imaging Syst Technol, 23, 71–84, 2013  相似文献   
992.
    
Magnetic resonance imaging (MRI), a non‐invasive, non‐radiative technique, is thought to lead to cellular or even molecular resolution if optimized targeted MR contrast agents are introduced. This would allow diagnosing progressive diseases in early stages. Here, it is shown that the high binding affinity of poly(ethylene glycol)‐gallol (PEG‐gallol) allows freeze drying and re‐dispersion of 9 ± 2‐nm iron oxide cores individually stabilized with ≈9‐nm‐thick stealth coatings, yielding particle stability for at least 20 months. Particle size, stability, and magnetic properties of PEGylated particles are compared to Feridex, a commercially available untargeted negative MR contrast agent. Biotin‐PEG(3400)‐gallol/methoxy‐PEG(550)‐gallol stabilized nanoparticles are further functionalized with biotinylated human anti‐VCAM‐1 antibodies using the biotin–neutravidin linkage. Binding kinetics and excellent specificity of these nanoparticles are demonstrated using quartz crystal microbalance with dissipation monitoring (QCM‐D). These MR contrast agents can be functionalized with any biotinylated ligand at controlled ligand surface density, rendering them a versatile research tool.  相似文献   
993.
    
Study of the thermodynamic behaviour of CaCl2-H2O-CO2 systems is important in different scientific areas in the chemical and petroleum engineering fields. For example, a system including salt- H20-CO2 is a common system in CO2 geological storage. During carbonate matrix acidizing, this mixture also appears as the spent acid. Hence, study of the behaviour of this system and the solubility of CO2 in CaCl2 brine in different thermodynamic conditions is critical. In this study, CO2 solubility in 0, 1.90 and 4.80 mol/L CaCl2 solutions at 328.15 to 375.15 K and 68.9 to 206.8 bar were measured. These values are normal for oil reservoirs. A popular thermodynamic model is available in the literature for estimating the CO2 solubility in pure water and NaC1 solutions. In this paper, the available model was modified by experimental work to be applicable for CaCl2 as well. Based on the measured data, the component interaction parameters in the base model were adjusted for a CaCl2-H2O-CO2 system. The developed model could predict CO2 solubility in different conditions with remarkable accuracy, particularly for high concentration solutions and at high pressures. This improvement is up to 65% better than in the base model. This model can be used in Darcy scale models for predicting wormhole propagation during carbonate matrix acidizing.  相似文献   
994.
    
Abstract

The better understanding and estimation of reservoir fluids properties have straight effects on accuracy of different processes such as simulation, well testing, and material balance calculations, so importance of accurate estimation of PVT properties such as solution gas-oil ratio is obvious. To this end, in the present paper, multilayer perceptron artificial neural network (MLP-ANN) is used as a novel predictive tool to estimate solution gas-oil ratio in terms of temperature, bubble point pressure, oil American Petroleum Institute gravity API, and gas specific gravity. Therefore, a total number of 1,137 experimental solution gas-oil ratios has been gathered from reliable databank for evaluation of model outputs. The different graphical and statistical analyses such as determination of average absolute relative deviation (AARD), the coefficient of determination (R2) and root mean square error (RMSE) were used to evaluate the performance of MLP-ANN algorithm. The comparisons show that MLP-ANN algorithm has great accuracy in prediction of solution gas-oil ratio, so it can be used as a simple tool to predict phase behavior of reservoir fluids.  相似文献   
995.
    
In gas industry, gas hydrate formation has both advantages and disadvantages. The best advantage of gas hydrate is Persian Gulf water sweetening, carbon dioxide capture, and gas storage, and its drawbacks are pressure drop, plugging, and explosion in pipelines. In recent years, using the inhibitors to prevent hydrate formation is being considered among researchers. In this study, the new equilibrium data for hydrate formation of inlet natural gas to Gachsaran NGL-1200 refinery with addition of Tri ethylene glycol (TEG) with mass concentration of 5% and 15% in distilled and Persian Gulf waters were measured by constant-volume method. The experimental results show that the hydrate formation conditions will be hard with the increase of TEG concentration in distillated and Persian Gulf waters. In other words, TEG addition to Persian Gulf water had more inhibitory effect in hydrate formation than TEG addition to distilled water. The hydrate formation temperature, in pressure range of 28–29 bars, reduced 0.3°C and 2.7°C for distilled water and 2.8°C and 4.6°C for Persian Gulf water in presence of TEG with mass concentration of 5% and 15%, respectively.  相似文献   
996.
    
In petroleum engineering, the transport phenomenon of proppants in a fracture caused by hydraulic fracturing is captured by hyperbolic partial differential equations (PDEs). The solution of this kind of PDEs may encounter smooth transitions, or there can be large gradients of the field variables. The numerical challenge posed in a shock situation is that high-order finite difference schemes lead to significant oscillations in the vicinity of shocks despite that such schemes result in higher accuracy in smooth regions. On the other hand, first-order methods provide monotonic solution convergences near the shocks, while giving poorer accuracy in the smooth regions. Accurate numerical simulation of such systems is a challenging task using conventional numerical methods. In this paper, we investigate several shock-capturing schemes. The competency of each scheme was tested against onedimensional benchmark problems as well as published numerical experiments. The numerical results have shown good performance of high-resolution finite volume methods in capturing shocks by resolving discontinuities while maintaining accuracy in the smooth regions. These methods along with Godunov splitting are applied to model proppant transport in fractures. It is concluded that the proposed scheme produces non-oscillatory and accurate results in obtaining a solution for proppant transport problems.  相似文献   
997.
    
Wellhead chokes are widely used in the petroleum industry. Owning to the high sensitivity of oil and gas production to choke size, an accurate correlation to specify choke performance is vitally important. The aim of this contribution was to develop effective relationships among the liquid flow rate, gas liquid ratio, flowing wellhead pressure, and surface wellhead choke size using the support vector machines (SVMs). The accurate data set was gathered from the 15 different fields containing 100 production samples from the vertical wells at wide ranges of wellhead choke sizes. This computational model was compared with the previous developed correlations in order to investigate its applicability for subcritical two phase flow regimes through wellhead chokes. Results confirmed amazing capability of the SVM to predict liquid flow rates. The value of R2 obtained was 0.9998 for the SVM model. This developed predictive tool can be of massive value for petroleum engineer to have accurate estimations of liquid flow rates through wellhead chocks.  相似文献   
998.
    
Gas hydrates may form in the petroleum and gas industry and can lead to significant problems such as plugging the pipelines and increasing velocity movement of the hydrate plugs in the pipelines. In this contribution, a simple strategy based on principal component analysis and partial least square methods has been utilized in order to estimate hydrate formation condition of carbon dioxide and tetra butyl ammonium chloride. In this regard, the developed tool has been evaluated by some reported data points in order to obtain its accuracy. This tool was simple to apply and can be of great help for gas transmission engineers to have an accurate estimation of hydrate conditions.  相似文献   
999.
    
The resources of heavy oil and bitumen are more than those of conventional light crude oil in the world. Diluting the bitumen with liquid solvent can decrease viscosity and increase the empty space between molecules. Tetradecane is a candidate as liquid solvent to dilute the bitumen. Owning to the sensitivity of enhanced oil recovery process, the accurate approximation for the viscosity of aforementioned mixture is important to decrease uncertainty. The aim of this study was to develop an effective relation between the viscosity of Athabasca bitumen and heavy n-alkane mixtures based on temperature, pressure, and weight percentage of n-tetradecane using the least square support vector machine. This computational model was compared with the previous developed correlation and its accuracy was confirmed. The value of R2 and MSE obtained 1.00 and 1.02 for this model, respectively. This developed predictive tool can be applied as an accurate estimation for any mixture of heavy oil with liquid solvent.  相似文献   
1000.
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